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Publications 2026

  1. Blaas L, Bartelt A. Fast & fuelious: the malate-aspartate shuttle in brown adipocyte lipid metabolism. FEBS J 2026

  2. Botman M, Huisman JMA, Drakaki A, Maas SL, Witalisz-Siepracka A, Stoiber D, van der Vorst EPC, Siebeler R, Hoeksema MA. Revealing an unconventional JAK1/2-STAT3 branch in macrophage IFN-gamma signaling. Cell Rep 2026

  3. Chong-Nguyen C, Fuentes Artiles R, Pilgrim T, Yilmaz B, Doring Y. The gut-heart axis in coronary artery disease: a scoping and narrative review of sex-based microbial and metabolic disparities. Biol Sex Differ 2026
  4. Cingir Koker S, Mhamane A, Geppert J, Shakir G, Guillamat-Prats R, Chen B, Katra P, Geiger M, Tsokanos FF, Wolff G, Szendrodi J, Rohm M, Daniel C, Maegdefessel L, Steffens S, Herzig S. Nuclear receptor co-factor TBL1X/TBL1XR1 T cell activity protects against atherosclerosis. Mol Metab 2026
  5. Cohen R, Duval V, Al-Rifai R, Maryam S, Santos-Zas I, Braik R, Diedisheim M, Jouve C, Nicoletti S, Thietart S, Guyon T, Chetrit L, Kral M, Doring Y, Weber C, Loupy A, Domenge O, Livrozet M, Hulot JS, Sakalli ET, Rizzo G, Saliba AE, Piollet M, Bruneval P, Tedgui A, Taleb S, Hermine O, Wicks I, Silvestre JS, Hayat S, Cochain C, Vivier E, Ait-Oufella H. NK cells promote cardiac cell death and regulate myelopoiesis in myocardial infarction. Nat Commun 2026
  6. Evans BR, Schulz J, Triantafyllidou V, Yerly A, Thakur M, Angliker N, Siegrist M, Jansen Y, Yan Y, Maas SL, Gold C, Farina FM, Bayer B, Bartelt A, Weber C, Wettich J, Maegdefessel L, Sachs N, Schindewolf M, Kotelis D, Noels H, Santovito D, van der Vorst EPC, Döring Y. ChemR23 prevents phenotypic switching of vascular smooth muscle cells into macrophage like foam cells in atherosclerosis. Cardiovasc Res 2025 
  7. Evans PC, Vilahur G, Kleinbongard P, Osto E, Remme CA, Madonna R, Aksentijevic D, Sourij H, Davidson SM, Santovito D, Gindlhuber J, Weber C, Linke WA, Lutgens E, Bertrand L, Dawson D, Bäck M, Norata GD, Wojta J, Perrino C. Novel cardiovascular metabolic risk factor mechanisms and therapeutic opportunities. Eur Heart J. 2026 
  8. Fell J, Pavez-Giani M, Koitka F, Kensah G, Santos GL, van der Vorst EPC, Lenz C, Salinas G, Busley AV, Fedorenko A, Hindmarsh R, Wolf CM, Lutz S, Hasenfuss G, Zimmermann WH, Wollnik B, Cyganek L. Targeting Interleukin-8-Mediated Cellular Crosstalk Reverses Hypertrophic Cardiomyopathy and Cardiac Fibrosis in Noonan Syndrome. Circulation 2026
  9. Haupt F, Tuleja A, Bernhard SM, Jung B, Rossler JK, Boon L, Vikkula M, Doring Y, Baumgartner I, Huber AT, von Tengg-Kobligk H. Volumetric perfusion fraction change in MR angiography for monitoring sclerotherapy-related changes in peripheral venous malformations. Eur J Radiol 2026
  10. Hense N, Gogels A, Mir B, van der Vorst EPC, Falgayrac G, Terliesner M, Goncalves I, Matic L, Edsfeldt A, Sun J, Hedin U, Hayat S, Thiel J, Ramirez-Torres MA, Barsoum M, Rauch A, Rauner M, Gombert A, Preisinger C, Noels H, Marx N, Goettsch C. 1-Phosphatidylinositol 3-Phosphate 5-Kinase Inhibition by Apilimod Promotes an Adipocyte-Like Vascular Smooth Muscle Cell Phenotype and Prevents Arterial Calcification. Circ Res 2026.
  11. Huchzermeier R, de Jong RJ, Rakateli L, Bonnin-Marquez A, Maas SL, Maassen-Pottgens C, Abschlag K, Jin H, Geiselhoringer AL, Triantafyllidou V, Santovito D, Jankowski J, Biessen EAL, Ohnmacht C, van der Vorst EPC. Whole-Body Knockout of the AhR (Aryl Hydrocarbon Receptor) Ameliorates Atherosclerosis Due to Altered Lipid Metabolism. Arterioscler Thromb Vasc Biol 2026
  12. Igl M, Haberbosch M, Hristov M, Reich F, van der Vorst EPC, Weber C, Bidzhekov K. miRNA-26b Is Associated with Increased Connexin-40 Expression in Endothelial Cells Under Flow Conditions. Int J Mol Sci 2026
  13. Li Y, Leberzammer J, Blanchet X, Duan R, Lacy M, Triantafyllidou V, Eckardt V, Briem E, Jung AS, Su R, Guerra J, Jansen Y, Hristov M, Enard W, Bernhagen J, Weber C, Atzler D, Bartelt A, Doring Y, Santovito D, Kaltner H, Ludwig AK, von Hundelshausen P. Galectin-1 induces macrophage immunometabolic reprogramming, modulates T cell immunity and attenuates atherosclerotic plaque formation. Atherosclerosis 2025

  14. Li N, Taherdangkoo K, Baatsch IM, Guduru T, Meng Q, Li S, Zhou Y, Li X, Zhu M, Polczer S, Geissler C, Briem E, Megens RTA, Na H, Kumbrink J, Richter D, Li Y, Jethwa C, Bartelt A, Doring Y, von Hundelshausen P, Enard W, Weber C, Nazari-Jahantigh M, Schober A. Mir147 Limits the Contribution of Non-Foamy Macrophages to Atherosclerosis. Circulation 2026

  15. Lip GYH, Rigby A, Weber C. Welcoming 2026: A Year of Innovation, Integrity, and Global Connection. Thromb Haemost. 2026
  16. Liskiewicz D, Novikoff A, Khalil A, Akindehin S, Campbell JE, Candela P, Castelino RL, Coupland C, Culot M, Dodson WS, Douros JD, Embring H, Feuchtinger A, Finan B, Garcia-Caceres C, Gao XB, Gosselet F, Grandl G, Gutgesell RM, Haas DT, Jastroch M, Karaoglu E, Kakimoto P, Kaltenbach AC, Keuper M, Kusminski CM, Leander DC, Liskiewicz A, Liu X, Maity-Kumar G, Martinez SM, Mowery SA, Nogueiras R, Paisley M, Perez-Tilve D, Petersen PSS, Pfluger PT, Prakash S, Steffens S, Cebrian-Serrano A, Tost M, Wean J, Weber C, Yoshida J, Gerhart-Hines Z, Horvath TL, Scherer PE, Seeley RJ, DiMarchi RD, Tschöp MH, Krahmer N, Knerr PJ, Müller TD. GLP-1R-GIPR-PPARα/γ/δ quintuple agonism corrects obesity and diabetes in mice. Nature. 2026 
  17. Meyer-Lindemann U, Borbil K, Schwab M, Moggio A, Shen R, Sharifi MA, Dang TA, Schories V, Rottenkolber R, Rapelius S, Hinterdobler J, Mauersberger C, von Scheidt M, Maegdefessel L, Wackerhage H, Köhler K, Berga-Švītiņa E, Vilne B, Hristov M, Weber C, Steffens S, McAlpine CS, Schunkert H, Kessler T, Sager HB. Exercise Reverses Mental Stress-Induced Vascular Inflammation and Builds Stress Resilience. JACC Basic Transl Sci. 2026

  18. Mohanta SK, Hong M, Deng X, Dou X, Xu X, Monjezi M, Li Y, Sun T, Wang Z, Habenicht AJR, Yin C. Artery Tertiary Lymphoid Organs Form Neuroimmune Cardiovascular Interfaces in Atherosclerosis. Immunol Rev 2026

  19. Muller JS, van der Vorst EPC. Macrophage-associated kinase signaling in atherosclerosis - a systematic review. Cell Commun Signal 2026. 

  20. Peters LJF, Bidzhekov K, Megens RTA, Jansen Y, Jin H, Jans A, Lin C, Haberbosch M, Bartneck M, Biessen EAL, Weber C, Doring Y, van der Vorst EPC. Nonhematopoietic MicroRNA-26b(-/-) Augments Atherosclerosis Development by Increasing Endothelial Inflammation and Leukocyte Adhesion-Brief Report. Arterioscler Thromb Vasc Biol 2026

  21. Santovito D, Weber C. Argonaute nuclear power: nuclear microRNAs control cardiac metabolism in heart failure with preserved ejection fraction. Eur Heart J 2026. 

  22. Schelemei P, Picard FSR, Park Y, Wollnitzke P, Nemade H, Lechner SK, Mehrkens D, Arkenberg P, Kobele AC, Wrobel J, Martinez Lagunas K, Wagner E, Guthoff H, Hof A, Cummings K, Al Zaidi M, Zimmer S, Roy J, Lindquist Liljeqvist M, Wolf D, Riffelmacher T, Ibing W, Wagenhauser MU, Schelzig H, Levkau B, Flogel U, Gerdes N, Karimpour M, Hillmer AM, Sengle G, Megens RTA, Weber C, Orecchioni M, Baldus S, Mollenhauer M, Winkels H. Olfr2 Promotes Recruitment of Monocytes via CX3CR1 in Abdominal Aortic Aneurysm. Circ Res 2026

  23. Schnidrig K, Thakur M, Tuleja A, Bernhard SM, Noels H, Kotelis D, Schindewolf M, Doring Y. Implications of inflammation and sex in lower extremity arterial disease. Eur J Clin Invest 2026
  24. Smudla A, Schochl H, Calatzis A, Gergely CR, Fazakas J. Is "Physiological Lysis" in Viscoelastometry a Plasmin-Mediated Process? Diagnostics (Basel) 2026

  25. Soehnlein O, Doring Y. Un-plexing atherosclerosis: how flow shapes arterial inflammation through PlexinD1. Eur Heart J 2026

  26. Sun T, Wang Z, Zhang C, Xu X, Zhang Y, Li Y, Yin C, Mohanta SK, Habenicht AJR. Artery Tertiary Lymphoid Organs Establish Biological Platforms to Connect Atherosclerotic Plaques to the Brain. Curr Atheroscler Rep 2026
  27. Takov K, Depuydt MAC, Stevens CAT, Fogacci F, Vico TA, Da Dalt L, Mussbacher M, Oleksiak A, Hendrikx T, Cutruzzola A, Diez Benavente E, Neele AE, Parma L, Maas SL. Bridging discovery and clinical science: A framework for advancing atherosclerosis research using innovative models. Atherosclerosis 2026
  28. Thakur M, Quillard T, Angliker N, Siegrist M, Jansen Y, Yan Y, Wollenhaupt J, Goettsch C, Maegdefessel L, Sachs N, Schindewolf M, Kotelis D, Noels H, Doring Y. DDR1 Regulates Femoral Arterial Calcification in Lower-Extremity Artery Disease Through NF-Kappa B Activation. Acta Physiol (Oxf) 2026

  29. von Hundelshausen P, Siess W, Duan R, Bohnert T, Hopkins BT, Weber C. Involvement of Btk in Cardiovascular Disease and Its Therapeutic Targeting. Circulation 2026

  30.  Wang Z, Sun T, Zhang Y, Li Y, Zhang C, Dou X, Deng X, Li Z, Zhu J, Hong M, Ran Y, Wang S, Li L, Zheng J, Wen C, Zhang X, Lu S, Sagar, Mohanta SK, Habenicht AJR, Yin C. Fitness Training for gammadelta T cells in mouse and human atherosclerosis takes place in plaques and artery tertiary lymphoid organs. Genome Med 2026

  31. Weber C, Rigby A, Lip GYH. Thrombosis and Haemostasis 2025 Editors' Choice. Thromb Haemost. 2026
  32. Weber CF, Zacharowski K, Calatzis A, Lindner ML. Monitoring unfractionated heparin in ECMO and cardiac surgery: the search for a valid reference standard. Front Med (Lausanne) 2026

Publications 2025

  1. Amoah BY, Yao Bayamina S, Gborsong C, Owusu H, Asare GA, Yeboah EK, Ablakwa J, Hammond G. Modifiable life style factors and male reproductive health: a cross-sectional study in IVF clinic attendees in Ghana. Front Reprod Health 2025

  2. Annamalai K, Dilliker S, Buchholz E, Castro-Hernandez R, Panyam N, Pommeranz A, Wiederhake P, Wery von Limont N, Hempel N, Ebner V, Swarnkar S, Mohamed BA, Streckfuss-Bomeke K, Steffens S, Herzig S, Ebert A, Fischer A, Toischer K. Deregulation of m6A-RNA methylation impairs adaptive hypertrophic response and drives maladaptation via mTORC1-S6K1-hyperactivation and autophagy impairment. Cell Commun Signal 2025

  3. Andreoti TA, Maiolo M, Tuleja A, Döring Y, Schaller A, Vassella E, Boon LM, Baumgartner I, Bernhard SM, Zweier C, Vikkula M, Rössler J. Non-Hotspot PIK3CA Variants Have Higher Variant Allele Frequency and are More Common in Syndromic Vascular Malformations. Am J Med Genet A. 2025

  4. Asare Y, Yan G, Schlegl C, Prestel M, van der Vorst EPC, Teunissen AJP, Aronova A, Tosato F, Naser N, Caputo J, Prevot G, Azzun A, Wefers B, Wurst W, Schneider M, Forne I, Bidzhekov K, Naumann R, van der Laan SW, Brandhofer M, Cao J, Roth S, Malik R, Tiedt S, Mulder WJM, Imhof A, Liesz A, Weber C, Bernhagen J, Dichgans M. A cis-regulatory element controls expression of histone deacetylase 9 to fine-tune inflammasome-dependent chronic inflammation in atherosclerosis. Immunity 2025

  5. Azarshin SZ, Marashi M, Abedi Kichi Z, Boroumand MA, Behmanesh M. Hyperglycemia Increased The Expression of CALCRL G Protein-Coupled Receptor in Monocytes from Diabetic Patients. Cell J 2025

  6. Ben-Aicha S, van der Vorst EPC. Shaping the future of cardiovascular research: a focus on cardioimmunology. Eur Heart J 2025

  7. Bonfiglio CA, Lacy M, Triantafyllidou V, Farina FM, Janjic A, Nitz K, Wu Y, Bazioti V, Avcilar-Kucukgoze I, Marques YFS, Joppich M, Kumkum M, Röß K, Venkatasubramani AV, Imhof A, Enard W, Maegdefessel L, de Winther M, Weber C, Santovito D, Lutgens E, Atzler D. Ezh2 Shapes T Cell Plasticity to Drive Atherosclerosis. Circulation 2025

  8. Bonneuil WV, Watson DJ, Mohanta SK, Habenicht AJR, Moore JE, Jr., Frattolin J. Atherosclerosis increases adventitial pressure and limits solute transport via fluid-balance mechanisms. Biomech Model Mechanobiol 2025

  9. Bonnin-Marquez A, Jankowski J, Maas SL, Hermann J, Kahles F, Lellig M, Fliser D, Schunk S, Stamellou E, Berger M, Speer T, Kalim S, Leong Wong DW, van der Vorst EPC, Jankowski V. Guanidinylation compromises the anti-inflammatory and anti-oxidative properties of apolipoprotein A-I in chronic kidney disease progression. Kidney Int 2025

  10. Bonnin-Marquez A, Maas SL, Corcini-Berndt M, Van der Vorst EPC. Unbiased kinome profiling identifies key and novel mediators of chronic kidney disease in hyperlipidemic mice. Front Physiol 2025;

  11. Brunetta HS, Mori MA, Bartelt A. Oxidative Phosphorylation in Uncoupled Mitochondria. Bioessays 2025 

  12. Camprubi-Rimblas M, Tantinya N, Artigas A, Guillamat-Prats R. Pharmacological inhibition of the CCL2-CCR2 axis fails to reduce inflammation in a rat model of acute lung injury. Sci Rep 2025 

  13. Chen Z, Li S, Song X, Diagel A, Li L, Moggio A, Li Z, Chen Y, Dang T, Li M, Shen R, Ma A, Schwab M, Barbera N, Lehertshuber C, Romer A, Brizzi LF, Krefting J, Krüger N, Sager H, Boon R, Civelek M, Romanoski C, Lusis A, Kessler T, Maegdefessel L, Schober A, von Scheidt M, Björkegren J, Nazari-Jahantigh M, Schunkert H. An interplay of non-coding RNAs regulates CDH13 expression and affects endothelial function and coronary artery disease risk. Res Sq [Preprint]. Res Sq 2025 

  14. Chevigne A, Legler DF, Rot A, Sozzani S, Szpakowska M, Thelen M. International Union of Basic and Clinical Pharmacology. CXVIII. Update on the nomenclature for atypical chemokine receptors, including ACKR5. Pharmacol Rev 2025

  15. Chong-Nguyen C, Yilmaz B, Coles B, Sokol H, MacPherson A, Siepe M, Reineke D, Mosbahi S, Tomii D, Nakase M, Atighetchi S, Ferro C, Wingert C, Grani C, Pilgrim T, Windecker S, Blasco H, Dupuy C, Emond P, Banz Y, Losmanova T, Doring Y, Siontis GCM. A scoping review evaluating the current state of gut microbiota and its metabolites in valvular heart disease physiopathology. Eur J Clin Invest 2025

  16. Davidson SM, Andreadou I, Antoniades C, Bartunek J, Basso C, Brundel B, Byrne RA, Chiva-Blanch G, da Costa Martins P, Evans PC, Girao H, Giricz Z, Gollmann-Tepekoylu C, Guzik T, Gyongyosi M, Hubner N, Joner M, Kleinbongard P, Krieg T, Liehn E, Madonna R, Maguy A, Paillard M, Pesce M, Petersen SE, Schiattarella GG, Sluijter JPG, Steffens S, Streckfuss-Bomeke K, Thielmann M, Tucker A, Van Linthout S, Wijns W, Wojta J, Wu JC, Perrino C. Opportunities and challenges for the use of human samples in translational cardiovascular research: a scientific statement of the ESC Working Group on Cellular Biology of the Heart, the ESC Working Group on Cardiovascular Surgery, the ESC Council on Basic Cardiovascular Science, the ESC Scientists of Tomorrow, the European Association of Percutaneous Cardiovascular Interventions of the ESC, and the Heart Failure Association of the ESC. Cardiovasc Res 2025

  17. de la Puente-Secades S, Mikolajetz D, Gayrard N, Hermann J, Jankowski V, Bhargava S, Meyer A, Argiles A, Saritas T, van der Vorst EPC, Wu Z, Noels H, Tepel M, Alghamdi K, Ward D, Zidek W, Wolf M, Floege J, Schurgers L, Orth-Alampour S, Jankowski J. Vasoconstriction-inhibiting factor: an endogenous inhibitor of vascular calcification as a calcimimetic of calcium-sensing receptor. Cardiovasc Res 2025

  18. Egea V. HypoxamiRs: the hidden architects of tissue adaptation in hypoxia. Cell Death Dis 2025

  19. El Bounkari O, Zan C, Yang B, Ebert S, Wagner J, Bugar E, Kramer N, Bourilhon P, Kontos C, Zarwel M, Sinitski D, Milic J, Jansen Y, Kempf WE, Sachs N, Maegdefessel L, Ji H, Gokce O, Riols F, Haid M, Gerra S, Hoffmann A, Brandhofer M, Avdic M, Bucala R, Megens RTA, Willemsen N, Messerer D, Schulz C, Bartelt A, Harm T, Rath D, Doring Y, Gawaz M, Weber C, Kapurniotu A, Bernhagen J. An atypical atherogenic chemokine that promotes advanced atherosclerosis and hepatic lipogenesis. Nat Commun 2025

  20. Ghiasvand T, Karimi J, Khodadadi I, Yazdi A, Khazaei S, Kichi ZA, Hosseini SK. The interplay of LDLR, PCSK9, and lncRNA- LASER genes expression in coronary artery disease: implications for therapeutic interventions. Prostaglandins Other Lipid Mediat 2025

  21. Gottschlich A, Grünmeier R, Hoffmann GV, Nandi S, Kavaka V, Müller PJ, Jobst J, Öner A, Kaiser R, Gärtig J, Piseddu I, Frenz-Wiessner S, Fairley SD, Schulz H, Igl V, Janert TA, di Fina L, Mulkers M, Thomas M, Briukhovetska D, Simnica D, Carlini E, Tsiverioti CA, Trefny MP, Lorenzini T, Märkl F, Mesquita P, Brabenec R, Strzalkowski T, Stock S, Michaelides S, Hellmuth J, Thelen M, Reinke S, Klapper W, Gelebart PF, Nicolai L, Marr C, Beltrán E, Megens RTA, Klein C, Baran-Marszak F, Rosenwald A, von Bergwelt-Baildon M, Bröckelmann PJ, Endres S, Kobold S. Dissection of single-cell landscapes for the development of chimeric antigen receptor T cells in Hodgkin lymphoma. Blood 2025

  22. Gutjahr JC, Hub E, Anderson CA, Samus M, Artinger K, Gomez EA, Ratswohl C, Wickli N, Raum M, Dufton N, Dalli J, Burden JJ, Duchene J, Rot A. Intracellular and nuclear CXCR4 signaling promotes terminal erythroblast differentiation and enucleation. Sci Signal 2025

  23. Gultom M, Lin L, Brandt CB, Milusev A, Despont A, Shaw J, Doring Y, Luo Y, Rieben R. Sustained Vascular Inflammatory Effects of SARS-CoV-2 Spike Protein on Human Endothelial Cells. Inflammation 2025

  24. Hristov M, Weber C. Monocyte Subsets in Cardiovascular Disease: A Biomarker Perspective. Thromb Haemost 2025

  25. Huchzermeier R, van der Vorst EPC. Aryl hydrocarbon receptor (AHR) and nuclear factor erythroid-derived 2-like 2 (NRF2): An important crosstalk in the gut-liver axis. Biochem Pharmacol 2025

  26. Jin H, Maas SL, Zou Y, Lu C, Yu B, Huchzermeier R, Nadeau S, Dos Santos J, Gijbels M, Mees BME, Smirnov E, Matic L, Hedin U, Maffia P, Monaco C, Sluimer JC, Martins GA, van der Vorst EPC, Biessen EAL. Identification of a PRDM1-regulated T cell network to regulate atherosclerotic plaque inflammation. Genome Med 2025

  27. Kang Z, Yang M, Liu Y, Gui Y, Dong Y, Zhou H, Zhang Z, Li M, Fan H, Li Z, Lu J, Li J, Zhu R, Yin C, Liu B, Jiang F, Huang K, Sarapultsev A, Li F, Zhang G, Zhao L, Wang Y, Ning Y, Cheng X, Mohanta SK, Yin C, Luo S, Habenicht AJR, Hu D. Myocardial mitochondrial antiviral signaling protein promotes heart Ischemia-reperfusion injury via RIG-I signaling in mice. Nat Commun 2025

  28. Katoozian F, Abedi Kichi Z, Sharifi R, Shirvani-Farsani Z. The Expression Analysis of Long Non-coding RNAs Related to Wnt/beta-Catenin Signaling in Pancreatic Cancer Patients. Biochem Genet 2025

  29. Kirmes K, Han J, Klug M, Bloxham CJ, Babyak O, Bernett J, Arend L, Manz Q, Raka L, Schwartz L, Hoffmann M, Rosenbaum M, Ruland J, Ciora OA, Louadi Z, Tsoy O, Newaz K, Modica J, Dioguardi CC, Peano C, Muller M, Santovito D, Viggiani G, Kuhne S, von Scheidt M, Nicolai L, Wu T, Baumbach J, Chiarito M, Laugwitz KL, Condorelli G, Raake PWJ, List M, Bernlochner I, Bongiovanni D. Reticulated platelets in coronary artery disease: a multidimensional approach unveils prothrombotic signalling and novel therapeutic targets. Eur Heart J 2025

  30. Koker SC, Tsokanos FF, El-Merahbi R, Jha AK, Cicatelli K, Weber P, Mhamane A, Kaltenecker D, Morigny P, Loft A, Klepac K, Maida A, Molocea CE, Hass D, Vogl ES, Alfaro AJ, Sun W, Zitzelsberger H, Unger K, Szendrodi J, Li Y, Diaz MB, Wolfrum C, Bartelt A, Herzig S, Georgiadi A. The TBLR1/TBL1 Co-Factor Complex Acts as a Transcriptional Checkpoint in the Brown Adipose Tissue Response to Prolonged Cold Exposure. FASEB J 2025

  31. Lauxen JS, Vondenhoff S, Junho CVC, Martin P, Fleig S, Schutt K, Schulze-Spate U, Soehnlein O, Prates-Roma L, Doring Y, Baaten C, Noels H. Neutrophil Function in Patients With Chronic Kidney Disease: A Systematic Review and Meta-Analysis. Acta Physiol (Oxf) 2025

  32. Lip GYH, Rigby A, Weber C. Welcoming 2025—A Year of Collaboration and Progress. Thromb Haemost 2025

  33. Martini E, Cremonesi M, Felicetta A, Serio S, Puccio S, Pelamatti E, van Beek JJP, Papadopoulou V, Catalano C, Fanuele F, Giuliano D, Basso G, Bonfiglio CA, Panico C, Vacchiano M, Carullo P, Papa L, D'Andrea C, Tuzger N, Marchini S, Magistroni P, Deaglio S, Amoroso A, Lugli E, Condorelli G, Kallikourdis M. Autoimmune-Like Mechanism in Heart Failure Enables Preventive Vaccine Therapy. Circ Res 2025

  34. Matta L, Blaas L, Gibis C, Guerra J. Functions require junctions: endurance exercise protects from age-induced alterations of the neuromuscular system. J Physiol 2025
  35. Matta L, Weber P, Erener S, Walth-Hummel A, Hass D, Buhler LK, Klepac K, Szendroedi J, Guerra J, Rohm M, Sterr M, Lickert H, Bartelt A, Herzig S. Chronic intermittent fasting impairs beta cell maturation and function in adolescent mice. Cell Rep 2025
  36. Möller-Ramon Z, Aslani M, Sobczak N, Hristov M, Weber C, Rot A, Duchêne J. The 129 strain-derived passenger mutations in ACKR1-deficient mice alter the expression of PYHIN and Fc-gamma receptor genes. Journal of Leukocyte Biology 2025
  37. Markwirth P, Selejan SR, Hohl M, Schunk SJ, Muller A, Wagenpfeil S, Wagmann L, Kahles F, Tokcan M, Therre M, van der Vorst EPC, Rau M, Noels H, Wollenhaupt J, Mahfoud F, Bohm M. Renal Denervation Improves Uremic Cardiomyopathy in Rats With Chronic Kidney Disease. J Am Heart Assoc 2025
  38. Metz F, Beilmann J, Bats SH, Latoscha A, Witte G, Megens RTA, Hopfner KP, Thorell K, Fischer W, Terradot L, Suerbaum S, Josenhans C. Functional and intricate interaction network connecting Helicobacter pylori Cag type 4 secretion system surface proteins with outer membrane proteins HopQ and HopZ. Microlife 2025
  39. Mohanta SK, Heron C, Klaus-Bergmann A, Horstmann H, Brakenhielm E, Giannarelli C, Habenicht AJR, Gerhardt H, Weber C. Metabolic and Immune Crosstalk in Cardiovascular Disease. Circulation Research 2025
  40. Nageswaran V, Carreras A, Reinshagen L, Beck KR, Steinfeldt J, Henricsson M, Ramezani Rad P, Peters L, Strassler ET, Lim J, Verhaar B, Doring Y, Weber C, Konig M, Steinhagen-Thiessen E, Demuth I, Krankel N, Leistner DM, Potente M, Nieuwdorp M, Knaus P, Kuebler WM, Ferrell M, Nemet I, Hazen SL, Landmesser U, Backhed F, Haghikia A. Gut Microbial Metabolite Imidazole Propionate Impairs Endothelial Cell Function and Promotes the Development of Atherosclerosis. Arterioscler Thromb Vasc Biol 2025
  41. Nahrendorf M, Kumowski N, Steffens S. Neutrophils in Myocardial Infarction. JACC Basic Transl Sci. 2025 

  42. Noels H, van der Vorst EPC, Rubin S, Emmett A, Marx N, Tomaszewski M, Jankowski J. Renal-Cardiac Crosstalk in the Pathogenesis and Progression of Heart Failure. Circ Res 2025

  43. Ofoghi A, Kotschi S, Lemmer IL, Haas DT, Willemsen N, Bayer B, Jung AS, Moller S, Haberecht-Muller S, Kruger E, Krahmer N, Bartelt A. Activating the NFE2L1-ubiquitin-proteasome system by DDI2 protects from ferroptosis. Cell Death Differ 2025

  44. Pannhausen J, Chughtai AA, Yuce CL, Melzer MK, Ma Y, Seillier L, van der Vorst EPC, Andrieux G, Wirtz J, Leypold S, Kuhnel MP, Hoffmann P, Heilmann-Heimbach S, Boerries M, Kleger A, Saar M, Eble MJ, Jonigk DD, Gaisa NT, Rose M. Targeting ATR offers multifaceted treatment strategies involving RAD51-mediated compensatory DNA repair in bladder cancer. J Exp Clin Cancer Res 2025

  45. Parma L, Sachs N, Sobczak N, Li Z, Merchant K, Pauli J, Depuydt MAC, Wezel A, Smeets HJ, Bot I, Slütter B, Maegdefessel L, Weber C, Duchêne J, Megens RTA. CXCL12 Derived From ACKR1+ Intraplaque Neovessels Mediates CD8 + T Cell Recruitment in Human Atherosclerosis. Circulation 2025

  46. Perrotta S, Carnevale L, Perrotta M, Pallante F, Mikolajczyk TP, Fardella V, Migliaccio A, Fardella S, Nejat S, Kapelak B, Zonfrilli A, Pacella J, Mastroiacovo F, Carnevale R, Bain C, Puhl SL, D'Agostino G, Epelman S, Guzik TJ, Lembo G, Carnevale D. A heart-brain-spleen axis controls cardiac remodeling to hypertensive stress. Immunity 2025

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Highlights

Atherosclerosis: how CD8+ T cells accumulate into plaques

25 Feb 2025 | News | Publication

CIRCULATION 2025 ➤ IPEK scientists from the Duchêne-Megens Lab identify a crucial signaling pathway – with therapeutic potential