Publications 2018
- Aarts S, Reiche ME, den Toom M, Beckers L, Gijbels MJJ, Gerdes N, de Winther MPJ, Lutgens E. Macrophage CD40 plays a minor role in obesity-induced metabolic dysfunction. PLoS One 2018; 13(8): e0202150. https://www.ncbi.nlm.nih.gov/pubmed/30096208
- Ameti R, Melgrati S, Radice E, Cameroni E, Hub E, Thelen S, Rot A, Thelen M. Characterization of a chimeric chemokine as a specific ligand for ACKR3. J Leukoc Biol 2018; 104(2): 391-400. https://www.ncbi.nlm.nih.gov/pubmed/29601107
- Atzler D, de Winther MPJ. DARC matter(s) for inflammatory cells. Cardiovasc Res 2018; 114(2): e11-e13. https://www.ncbi.nlm.nih.gov/pubmed/29373721
- Baardman J, Verberk SGS, Prange KHM, van Weeghel M, van der Velden S, Ryan DG, Wust RCI, Neele AE, Speijer D, Denis SW, Witte ME, Houtkooper RH, O'Neill L A, Knatko EV, Dinkova-Kostova AT, Lutgens E, de Winther MPJ, Van den Bossche J. A Defective Pentose Phosphate Pathway Reduces Inflammatory Macrophage Responses during Hypercholesterolemia. Cell Rep 2018; 25(8): 2044-2052 e2045. https://www.ncbi.nlm.nih.gov/pubmed/30463003
- Baaten C, Meacham S, de Witt SM, Feijge MAH, Adams DJ, Akkerman JN, Cosemans J, Grassi L, Jupe S, Kostadima M, Mattheij NJA, Prins MH, Ramirez-Solis R, Soehnlein O, Swieringa F, Weber C, White JK, Ouwehand WH, Heemskerk JWM. A synthesis approach of mouse studies to identify genes and proteins in arterial thrombosis and bleeding. Blood 2018; 132(24): e35-e46. https://www.ncbi.nlm.nih.gov/pubmed/30275110
- Bahls M, Atzler D, Markus MRP, Friedrich N, Boger RH, Volzke H, Felix SB, Schwedhelm E, Dorr M. Low-Circulating Homoarginine is Associated with Dilatation and Decreased Function of the Left Ventricle in the General Population. Biomolecules 2018; 8(3): 63. https://www.ncbi.nlm.nih.gov/pubmed/30061520
- Baldassarri F, Schwedhelm E, Atzler D, Boger RH, Cordts K, Haller B, Pressler A, Muller S, Suchy C, Wachter R, Dungen HD, Hasenfuss G, Pieske B, Halle M, Edelmann F, Duvinage A. Relationship between exercise intervention and NO pathway in patients with heart failure with preserved ejection fraction. Biomarkers 2018; 23(6): 540-550. https://www.ncbi.nlm.nih.gov/pubmed/29619838
- Braza MS, van Leent MMT, Lameijer M, Sanchez-Gaytan BL, Arts RJW, Perez-Medina C, Conde P, Garcia MR, Gonzalez-Perez M, Brahmachary M, Fay F, Kluza E, Kossatz S, Dress RJ, Salem F, Rialdi A, Reiner T, Boros P, Strijkers GJ, Calcagno CC, Ginhoux F, Marazzi I, Lutgens E, Nicolaes GAF, Weber C, Swirski FK, Nahrendorf M, Fisher EA, Duivenvoorden R, Fayad ZA, Netea MG, Mulder WJM, Ochando J. Inhibiting Inflammation with Myeloid Cell-Specific Nanobiologics Promotes Organ Transplant Acceptance. Immunity 2018; 49(5): 819-828 e816. https://www.ncbi.nlm.nih.gov/pubmed/30413362
- Busygina K, Jamasbi J, Seiler T, Deckmyn H, Weber C, Brandl R, Lorenz R, Siess W. Oral Bruton tyrosine kinase inhibitors selectively block atherosclerotic plaque-triggered thrombus formation in humans. Blood 2018; 131(24): 2605-2616. https://www.ncbi.nlm.nih.gov/pubmed/29559479
- Caporali A, Back M, Daemen MJ, Hoefer IE, Jones EA, Lutgens E, Matter CM, Bochaton-Piallat ML, Siekmann AF, Sluimer JC, Steffens S, Tunon J, Vindis C, Wentzel JJ, Yla-Herttuala S, Evans PC. Future directions for therapeutic strategies in post-ischaemic vascularization: a position paper from European Society of Cardiology Working Group on Atherosclerosis and Vascular Biology. Cardiovasc Res 2018; 114(11): 1411-1421. https://www.ncbi.nlm.nih.gov/pubmed/30016405
- Casanova-Acebes M, Nicolas-Avila JA, Li JL, Garcia-Silva S, Balachander A, Rubio-Ponce A, Weiss LA, Adrover JM, Burrows K, N AG, Ballesteros I, Devi S, Quintana JA, Crainiciuc G, Leiva M, Gunzer M, Weber C, Nagasawa T, Soehnlein O, Merad M, Mortha A, Ng LG, Peinado H, Hidalgo A. Neutrophils instruct homeostatic and pathological states in naive tissues. J Exp Med 2018; 215(11): 2778-2795. https://www.ncbi.nlm.nih.gov/pubmed/30282719
- Chevre R, Silvestre-Roig C, Soehnlein O. Nutritional Modulation of Innate Immunity: The Fat-Bile-Gut Connection. Trends Endocrinol Metab 2018; 29(10): 686-698. https://www.ncbi.nlm.nih.gov/pubmed/30197155
- Curaj A, Wu Z, Rix A, Gresch O, Sternkopf M, Alampour-Rajabi S, Lammers T, van Zandvoort M, Weber C, Koenen RR, Liehn EA, Kiessling F. Molecular Ultrasound Imaging of Junctional Adhesion Molecule A Depicts Acute Alterations in Blood Flow and Early Endothelial Dysregulation. Arterioscler Thromb Vasc Biol 2018; 38(1): 40-48. https://www.ncbi.nlm.nih.gov/pubmed/29191926
- Daugherty A, Lu HS, Hegele RA, Mackman N, Rader DJ, Schmidt AM, Weber C. Response by Daugherty et al to Letter Regarding Article, "Consideration of Sex Differences in Design and Reporting of Experimental Arterial Pathology Studies: A Statement From the Arteriosclerosis, Thrombosis, and Vascular Biology Council". Arterioscler Thromb Vasc Biol 2018; 38(6): e101-e102. https://www.ncbi.nlm.nih.gov/pubmed/29793996
- den Harder AM, de Jong PA, de Groot MCH, Wolterink JM, Budde RPJ, Isgum I, van Solinge WW, Ten Berg MJ, Lutgens E, Veldhuis WB, Haitjema S, Hoefer IE, Leiner T. Commonly available hematological biomarkers are associated with the extent of coronary calcifications. Atherosclerosis 2018; 275: 166-173. https://www.ncbi.nlm.nih.gov/pubmed/29920437
- Di Francesco A, Fedrigo M, Santovito D, Natarelli L, Castellani C, De Pascale F, Toscano G, Fraiese A, Feltrin G, Benazzi E, Nocco A, Thiene G, Valente M, Valle G, Schober A, Gerosa G, Angelini A. MicroRNA signatures in cardiac biopsies and detection of allograft rejection. J Heart Lung Transplant 2018; 37(11): 1329-1340. https://www.ncbi.nlm.nih.gov/pubmed/30174164
- Dickhout A, Koenen RR. Extracellular Vesicles as Biomarkers in Cardiovascular Disease; Chances and Risks. Front Cardiovasc Med 2018; 5: 113. https://www.ncbi.nlm.nih.gov/pubmed/30186839
- Domschke G, Linden F, Pawig L, Hafner A, Akhavanpoor M, Reymann J, Doesch AO, Erbel C, Weber C, Katus HA, Noels H, Erfle H, Gleissner CA, Runz H. Systematic RNA-interference in primary human monocyte-derived macrophages: A high-throughput platform to study foam cell formation. Sci Rep 2018; 8(1): 10516. https://www.ncbi.nlm.nih.gov/pubmed/30002403
- Doring Y, van der Vorst EPC. Gouty Offense in Patients With Obstructive Coronary Artery Disease Despite State-of-the-Art Therapy. J Am Heart Assoc 2018; 7(16): e010322. https://www.ncbi.nlm.nih.gov/pubmed/30369331
- Dorn T, Kornherr J, Parrotta EI, Zawada D, Ayetey H, Santamaria G, Iop L, Mastantuono E, Sinnecker D, Goedel A, Dirschinger RJ, My I, Laue S, Bozoglu T, Baarlink C, Ziegler T, Graf E, Hinkel R, Cuda G, Kaab S, Grace AA, Grosse R, Kupatt C, Meitinger T, Smith AG, Laugwitz KL, Moretti A. Interplay of cell-cell contacts and RhoA/MRTF-A signaling regulates cardiomyocyte identity. EMBO J 2018; 37(12): e98133. https://www.ncbi.nlm.nih.gov/pubmed/29764980
- Eikendal ALM, Bots ML, Gohar A, Lutgens E, Hoefer IE, den Ruijter HM, Leiner T. Circulating levels of P-selectin and E-selectin relate to cardiovascular magnetic resonance-derived aortic characteristics in young adults from the general population, a cross-sectional study. J Cardiovasc Magn Reson 2018; 20(1): 54. https://www.ncbi.nlm.nih.gov/pubmed/30068374
- Evrard M, Kwok IWH, Chong SZ, Teng KWW, Becht E, Chen J, Sieow JL, Penny HL, Ching GC, Devi S, Adrover JM, Li JLY, Liong KH, Tan L, Poon Z, Foo S, Chua JW, Su IH, Balabanian K, Bachelerie F, Biswas SK, Larbi A, Hwang WYK, Madan V, Koeffler HP, Wong SC, Newell EW, Hidalgo A, Ginhoux F, Ng LG. Developmental Analysis of Bone Marrow Neutrophils Reveals Populations Specialized in Expansion, Trafficking, and Effector Functions. Immunity 2018; 48(2): 364-379 e368. https://www.ncbi.nlm.nih.gov/pubmed/29466759
- Faller KME, Atzler D, McAndrew DJ, Zervou S, Whittington HJ, Simon JN, Aksentijevic D, Ten Hove M, Choe CU, Isbrandt D, Casadei B, Schneider JE, Neubauer S, Lygate CA. Impaired cardiac contractile function in arginine:glycine amidinotransferase knockout mice devoid of creatine is rescued by homoarginine but not creatine. Cardiovasc Res 2018; 114(3): 417-430. https://www.ncbi.nlm.nih.gov/pubmed/29236952
- Girbl T, Lenn T, Perez L, Rolas L, Barkaway A, Thiriot A, Del Fresno C, Lynam E, Hub E, Thelen M, Graham G, Alon R, Sancho D, von Andrian UH, Voisin MB, Rot A, Nourshargh S. Distinct Compartmentalization of the Chemokines CXCL1 and CXCL2 and the Atypical Receptor ACKR1 Determine Discrete Stages of Neutrophil Diapedesis. Immunity 2018; 49(6): 1062-1076 e1066. https://www.ncbi.nlm.nih.gov/pubmed/30446388
- Gomez-Moreno D, Adrover JM, Hidalgo A. Neutrophils as effectors of vascular inflammation. Eur J Clin Invest 2018; 48 Suppl 2(S2): e12940. https://www.ncbi.nlm.nih.gov/pubmed/29682731
- Hinkel R, Klett K, Bahr A, Kupatt C. Thymosin beta4-mediated protective effects in the heart. Expert Opin Biol Ther 2018; 18(sup1): 121-129. https://www.ncbi.nlm.nih.gov/pubmed/30063857
- Hoogeveen RM, Nahrendorf M, Riksen NP, Netea MG, de Winther MPJ, Lutgens E, Nordestgaard BG, Neidhart M, Stroes ESG, Catapano AL, Bekkering S. Monocyte and haematopoietic progenitor reprogramming as common mechanism underlying chronic inflammatory and cardiovascular diseases. Eur Heart J 2018; 39(38): 3521-3527. https://www.ncbi.nlm.nih.gov/pubmed/29069365
- Horckmans M, Bianchini M, Santovito D, Megens RTA, Springael JY, Negri I, Vacca M, Di Eusanio M, Moschetta A, Weber C, Duchene J, Steffens S. Pericardial Adipose Tissue Regulates Granulopoiesis, Fibrosis, and Cardiac Function After Myocardial Infarction. Circulation 2018; 137(9): 948-960. https://www.ncbi.nlm.nih.gov/pubmed/29167227
- Jagschies L, Hirschvogel M, Matallo J, Maier A, Mild K, Brunner H, Hinkel R, Gee MW, Radermacher P, Wildhirt SM, Hafner S. Individualized Biventricular Epicardial Augmentation Technology in a Drug-Induced Porcine Failing Heart Model. ASAIO J 2018; 64(4): 480-488. https://www.ncbi.nlm.nih.gov/pubmed/29028694
- Kuipers EN, Kantae V, Maarse BCE, van den Berg SM, van Eenige R, Nahon KJ, Reifel-Miller A, Coskun T, de Winther MPJ, Lutgens E, Kooijman S, Harms AC, Hankemeier T, van der Stelt M, Rensen PCN, Boon MR. High Fat Diet Increases Circulating Endocannabinoids Accompanied by Increased Synthesis Enzymes in Adipose Tissue. Front Physiol 2018; 9: 1913. https://www.ncbi.nlm.nih.gov/pubmed/30687125
- Kusters PJH, Lutgens E, Seijkens TTP. Exploring immune checkpoints as potential therapeutic targets in atherosclerosis. Cardiovasc Res 2018; 114(3): 368-377. https://www.ncbi.nlm.nih.gov/pubmed/29309533
- Lameijer M, Binderup T, van Leent MMT, Senders ML, Fay F, Malkus J, Sanchez-Gaytan BL, Teunissen AJP, Karakatsanis N, Robson P, Zhou X, Ye Y, Wojtkiewicz G, Tang J, Seijkens TTP, Kroon J, Stroes ESG, Kjaer A, Ochando J, Reiner T, Perez-Medina C, Calcagno C, Fisher EA, Zhang B, Temel RE, Swirski FK, Nahrendorf M, Fayad ZA, Lutgens E, Mulder WJM, Duivenvoorden R. Efficacy and safety assessment of a TRAF6-targeted nanoimmunotherapy in atherosclerotic mice and non-human primates. Nat Biomed Eng 2018; 2(5): 279-292. https://www.ncbi.nlm.nih.gov/pubmed/30936448
- Langin M, Mayr T, Reichart B, Michel S, Buchholz S, Guethoff S, Dashkevich A, Baehr A, Egerer S, Bauer A, Mihalj M, Panelli A, Issl L, Ying J, Fresch AK, Buttgereit I, Mokelke M, Radan J, Werner F, Lutzmann I, Steen S, Sjoberg T, Paskevicius A, Qiuming L, Sfriso R, Rieben R, Dahlhoff M, Kessler B, Kemter E, Kurome M, Zakhartchenko V, Klett K, Hinkel R, Kupatt C, Falkenau A, Reu S, Ellgass R, Herzog R, Binder U, Wich G, Skerra A, Ayares D, Kind A, Schonmann U, Kaup FJ, Hagl C, Wolf E, Klymiuk N, Brenner P, Abicht JM. Consistent success in life-supporting porcine cardiac xenotransplantation. Nature 2018; 564(7736): 430-433. https://www.ncbi.nlm.nih.gov/pubmed/30518863
- Leoni G, Soehnlein O. (Re) Solving Repair After Myocardial Infarction. Front Pharmacol 2018; 9: 1342. https://www.ncbi.nlm.nih.gov/pubmed/30534069
- Lu HS, Schmidt AM, Hegele RA, Mackman N, Rader DJ, Weber C, Daugherty A. Reporting Sex and Sex Differences in Preclinical Studies. Arterioscler Thromb Vasc Biol 2018; 38(10): e171-e184. https://www.ncbi.nlm.nih.gov/pubmed/30354222
- Maas SL, Soehnlein O, Viola JR. Organ-Specific Mechanisms of Transendothelial Neutrophil Migration in the Lung, Liver, Kidney, and Aorta. Front Immunol 2018; 9: 2739. https://www.ncbi.nlm.nih.gov/pubmed/30538702
- Mederos YSM, Gudermann T, Storch U. Emerging Roles of Diacylglycerol-Sensitive TRPC4/5 Channels. Cells 2018; 7(11): 218. https://www.ncbi.nlm.nih.gov/pubmed/30463370
- Natarelli L, Geissler C, Csaba G, Wei Y, Zhu M, di Francesco A, Hartmann P, Zimmer R, Schober A. miR-103 promotes endothelial maladaptation by targeting lncWDR59. Nat Commun 2018; 9(1): 2645. https://www.ncbi.nlm.nih.gov/pubmed/29980665
- Neele AE, de Winther MPJ. Repressing the repressor: Ezh2 mediates macrophage activation. J Exp Med 2018; 215(5): 1269-1271. https://www.ncbi.nlm.nih.gov/pubmed/29691302
- Neele AE, Gijbels MJJ, van der Velden S, Hoeksema MA, Boshuizen MCS, Prange KHM, Chen HJ, Van den Bossche J, van Roomen C, Shami A, Levels JHM, Kroon J, Lucas T, Dimmeler S, Lutgens E, de Winther MPJ. Myeloid Kdm6b deficiency results in advanced atherosclerosis. Atherosclerosis 2018; 275: 156-165. https://www.ncbi.nlm.nih.gov/pubmed/29908485
- Nicolas-Avila JA, Hidalgo A, Ballesteros I. Specialized functions of resident macrophages in brain and heart. J Leukoc Biol 2018; 104(4): 743-756. https://www.ncbi.nlm.nih.gov/pubmed/29947422
- Niekamp C, Atzler D, Ojeda FM, Sinning CR, Lackner KJ, Boger RH, Munzel T, Beutel ME, Schmidtmann I, Pfeiffer N, Leuschner A, Blankenberg S, Wild PS, Zeller T, Schwedhelm E, Schnabel RB. Cross-Sectional Associations between Homoarginine, Intermediate Phenotypes, and Atrial Fibrillation in the Community-The Gutenberg Health Study. Biomolecules 2018; 8(3): 86. https://www.ncbi.nlm.nih.gov/pubmed/30200232
- Pacher P, Steffens S, Hasko G, Schindler TH, Kunos G. Cardiovascular effects of marijuana and synthetic cannabinoids: the good, the bad, and the ugly. Nat Rev Cardiol 2018; 15(3): 151-166. https://www.ncbi.nlm.nih.gov/pubmed/28905873
- Patel J, Lutgens E. Scientists on the Spot: Esther Lutgens on the immune system and atherosclerosis. Cardiovasc Res 2018; 114(14): e113. https://www.ncbi.nlm.nih.gov/pubmed/30476016
- Paulin N, Viola JR, Maas SL, de Jong R, Fernandes-Alnemri T, Weber C, Drechsler M, Doring Y, Soehnlein O. Double-Strand DNA Sensing Aim2 Inflammasome Regulates Atherosclerotic Plaque Vulnerability. Circulation 2018; 138(3): 321-323. https://www.ncbi.nlm.nih.gov/pubmed/30012706
- Pfeiler S, Gerdes N. Atherosclerosis: cell biology and lipoproteins - focus on anti-inflammatory therapies. Curr Opin Lipidol 2018; 29(1): 53-55. https://www.ncbi.nlm.nih.gov/pubmed/29298275
- Pircher J, Czermak T, Ehrlich A, Eberle C, Gaitzsch E, Margraf A, Grommes J, Saha P, Titova A, Ishikawa-Ankerhold H, Stark K, Petzold T, Stocker T, Weckbach LT, Novotny J, Sperandio M, Nieswandt B, Smith A, Mannell H, Walzog B, Horst D, Soehnlein O, Massberg S, Schulz C. Cathelicidins prime platelets to mediate arterial thrombosis and tissue inflammation. Nat Commun 2018; 9(1): 1523. https://www.ncbi.nlm.nih.gov/pubmed/29670076
- Poller W, Dimmeler S, Heymans S, Zeller T, Haas J, Karakas M, Leistner DM, Jakob P, Nakagawa S, Blankenberg S, Engelhardt S, Thum T, Weber C, Meder B, Hajjar R, Landmesser U. Non-coding RNAs in cardiovascular diseases: diagnostic and therapeutic perspectives. Eur Heart J 2018; 39(29): 2704-2716. https://www.ncbi.nlm.nih.gov/pubmed/28430919
- Rami M, Guillamat-Prats R, Rinne P, Salvermoser M, Ring L, Bianchini M, Blanchet X, Megens RTA, Doring Y, Walzog B, Soehnlein O, Weber C, Faussner A, Steffens S. Chronic Intake of the Selective Serotonin Reuptake Inhibitor Fluoxetine Enhances Atherosclerosis. Arterioscler Thromb Vasc Biol 2018; 38(5): 1007-1019. https://www.ncbi.nlm.nih.gov/pubmed/29567680
- Renz BW, Takahashi R, Tanaka T, Macchini M, Hayakawa Y, Dantes Z, Maurer HC, Chen X, Jiang Z, Westphalen CB, Ilmer M, Valenti G, Mohanta SK, Habenicht AJR, Middelhoff M, Chu T, Nagar K, Tailor Y, Casadei R, Di Marco M, Kleespies A, Friedman RA, Remotti H, Reichert M, Worthley DL, Neumann J, Werner J, Iuga AC, Olive KP, Wang TC. beta2 Adrenergic-Neurotrophin Feedforward Loop Promotes Pancreatic Cancer. Cancer Cell 2018; 33(1): 75-90 e77. https://www.ncbi.nlm.nih.gov/pubmed/29249692
- Rinne P, Guillamat-Prats R, Rami M, Bindila L, Ring L, Lyytikainen LP, Raitoharju E, Oksala N, Lehtimaki T, Weber C, van der Vorst EPC, Steffens S. Palmitoylethanolamide Promotes a Proresolving Macrophage Phenotype and Attenuates Atherosclerotic Plaque Formation. Arterioscler Thromb Vasc Biol 2018; 38(11): 2562-2575. https://www.ncbi.nlm.nih.gov/pubmed/30354245
- Rinne P, Kadiri JJ, Velasco-Delgado M, Nuutinen S, Viitala M, Hollmen M, Rami M, Savontaus E, Steffens S. Melanocortin 1 Receptor Deficiency Promotes Atherosclerosis in Apolipoprotein E(-/-) Mice. Arterioscler Thromb Vasc Biol 2018; 38(2): 313-323. https://www.ncbi.nlm.nih.gov/pubmed/29284608
- Rouwet E, Lutgens E. 2016 Jeffrey M. Hoeg Award Lecture. Arterioscler Thromb Vasc Biol 2018; 38(8): 1678-1688. https://www.ncbi.nlm.nih.gov/pubmed/29930003
- Salas-Perdomo A, Miro-Mur F, Urra X, Justicia C, Gallizioli M, Zhao Y, Brait VH, Laredo C, Tudela R, Hidalgo A, Chamorro A, Planas AM. T Cells Prevent Hemorrhagic Transformation in Ischemic Stroke by P-Selectin Binding. Arterioscler Thromb Vasc Biol 2018; 38(8): 1761-1771. https://www.ncbi.nlm.nih.gov/pubmed/29903733
- Salvermoser M, Pick R, Weckbach LT, Zehrer A, Lohr P, Drechsler M, Sperandio M, Soehnlein O, Walzog B. Myosin 1f is specifically required for neutrophil migration in 3D environments during acute inflammation. Blood 2018; 131(17): 1887-1898. https://www.ncbi.nlm.nih.gov/pubmed/29487067
- Schmitz C, Noels H, El Bounkari O, Straussfeld E, Megens RTA, Sternkopf M, Alampour-Rajabi S, Krammer C, Tilstam PV, Gerdes N, Burger C, Kapurniotu A, Bucala R, Jankowski J, Weber C, Bernhagen J. Mif-deficiency favors an atheroprotective autoantibody phenotype in atherosclerosis. FASEB J 2018; 32(8): 4428-4443. https://www.ncbi.nlm.nih.gov/pubmed/29543531
- Schonhoff M, Weineck G, Hoppe J, Hornig S, Cordts K, Atzler D, Gerloff C, Boger R, Neu A, Schwedhelm E, Choe CU. Cognitive performance of 20 healthy humans supplemented with L-homoarginine for 4 weeks. J Clin Neurosci 2018; 50: 237-241. https://www.ncbi.nlm.nih.gov/pubmed/29396070
- Schumski A, Winter C, Doring Y, Soehnlein O. The Ins and Outs of Myeloid Cells in Atherosclerosis. J Innate Immun 2018; 10(5-6): 479-486. https://www.ncbi.nlm.nih.gov/pubmed/29669334
- Seijkens TTP, Lutgens E. Cardiovascular oncology: exploring the effects of targeted cancer therapies on atherosclerosis. Curr Opin Lipidol 2018; 29(5): 381-388. https://www.ncbi.nlm.nih.gov/pubmed/30074493
- Seijkens TTP, van Tiel CM, Kusters PJH, Atzler D, Soehnlein O, Zarzycka B, Aarts S, Lameijer M, Gijbels MJ, Beckers L, den Toom M, Slutter B, Kuiper J, Duchene J, Aslani M, Megens RTA, van 't Veer C, Kooij G, Schrijver R, Hoeksema MA, Boon L, Fay F, Tang J, Baxter S, Jongejan A, Moerland PD, Vriend G, Bleijlevens B, Fisher EA, Duivenvoorden R, Gerdes N, de Winther MPJ, Nicolaes GA, Mulder WJM, Weber C, Lutgens E. Targeting CD40-Induced TRAF6 Signaling in Macrophages Reduces Atherosclerosis. J Am Coll Cardiol 2018; 71(5): 527-542. https://www.ncbi.nlm.nih.gov/pubmed/29406859
- Soehnlein O. [Atherothrombosis : Novel therapeutic strategies]. Herz 2018; 43(2): 103-108. https://www.ncbi.nlm.nih.gov/pubmed/29236146
- Soehnlein O. Decision shaping neutrophil-platelet interplay in inflammation: From physiology to intervention. Eur J Clin Invest 2018; 48(2). https://www.ncbi.nlm.nih.gov/pubmed/29226390
- Soehnlein O, Bazioti V, Westerterp M. A Pad 4 Plaque Erosion. Circ Res 2018; 123(1): 6-8. https://www.ncbi.nlm.nih.gov/pubmed/29929967
- Steven S, Dib M, Hausding M, Kashani F, Oelze M, Kroller-Schon S, Hanf A, Daub S, Roohani S, Gramlich Y, Lutgens E, Schulz E, Becker C, Lackner KJ, Kleinert H, Knosalla C, Niesler B, Wild PS, Munzel T, Daiber A. CD40L controls obesity-associated vascular inflammation, oxidative stress, and endothelial dysfunction in high fat diet-treated and db/db mice. Cardiovasc Res 2018; 114(2): 312-323. https://www.ncbi.nlm.nih.gov/pubmed/29036612
- Stocker TJ, Pircher J, Skenderi A, Ehrlich A, Eberle C, Megens RTA, Petzold T, Zhang Z, Walzog B, Muller-Taubenberger A, Weber C, Massberg S, Ishikawa-Ankerhold H, Schulz C. The Actin Regulator Coronin-1A Modulates Platelet Shape Change and Consolidates Arterial Thrombosis. Thromb Haemost 2018; 118(12): 2098-2111. https://www.ncbi.nlm.nih.gov/pubmed/30453345
- Trevino-Villarreal JH, Reynolds JS, Bartelt A, Langston PK, MacArthur MR, Arduini A, Tosti V, Veronese N, Bertozzi B, Brace LE, Mejia P, Trocha K, Kajitani GS, Longchamp A, Harputlugil E, Gathungu R, Bird SS, Bullock AD, Figenshau RS, Andriole GL, Thompson A, Heeren J, Ozaki CK, Kristal BS, Fontana L, Mitchell JR. Dietary protein restriction reduces circulating VLDL triglyceride levels via CREBH-APOA5-dependent and -independent mechanisms. JCI Insight 2018; 3(21): e99470. https://www.ncbi.nlm.nih.gov/pubmed/30385734
- Tunon J, Back M, Badimon L, Bochaton-Piallat ML, Cariou B, Daemen MJ, Egido J, Evans PC, Francis SE, Ketelhuth DF, Lutgens E, Matter CM, Monaco C, Steffens S, Stroes E, Vindis C, Weber C, Hoefer IE, Atherosclerosis ESCWGo, Vascular B. Interplay between hypercholesterolaemia and inflammation in atherosclerosis: Translating experimental targets into clinical practice. Eur J Prev Cardiol 2018; 25(9): 948-955. https://www.ncbi.nlm.nih.gov/pubmed/29759006
- Vajen T, Koenen RR, Werner I, Staudt M, Projahn D, Curaj A, Sonmez TT, Simsekyilmaz S, Schumacher D, Mollmann J, Hackeng TM, Hundelshausen PV, Weber C, Liehn EA. Blocking CCL5-CXCL4 heteromerization preserves heart function after myocardial infarction by attenuating leukocyte recruitment and NETosis. Sci Rep 2018; 8(1): 10647. https://www.ncbi.nlm.nih.gov/pubmed/30006564
- van der Tuin SJL, Li Z, Berbee JFP, Verkouter I, Ringnalda LE, Neele AE, van Klinken JB, Rensen SS, Fu J, de Winther MPJ, Groen AK, Rensen PCN, Willems van Dijk K, Wang Y. Lipopolysaccharide Lowers Cholesteryl Ester Transfer Protein by Activating F4/80(+)Clec4f(+)Vsig4(+)Ly6C(-) Kupffer Cell Subsets. J Am Heart Assoc 2018; 7(6): e008105. https://www.ncbi.nlm.nih.gov/pubmed/29525783
- van der Vorst EPC, Weber C, Donners M. A Disintegrin and Metalloproteases (ADAMs) in Cardiovascular, Metabolic and Inflammatory Diseases: Aspects for Theranostic Approaches. Thromb Haemost 2018; 118(7): 1167-1175. https://www.ncbi.nlm.nih.gov/pubmed/29874690
- van der Vorst EPC, de Jong RJ, Donners M. Message in a Microbottle: Modulation of Vascular Inflammation and Atherosclerosis by Extracellular Vesicles. Front Cardiovasc Med 2018; 5: 2. https://www.ncbi.nlm.nih.gov/pubmed/29404342
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