Publications Tab Widgets
- Bherer C, Eveleigh R, Trajanoska K, St-Cyr J, Paccard A, Nadukkalam Ravindran P, Caron E, Bader Asbah N, McClelland P, Wei C, Baumgartner I, Schindewolf M, Doring Y, Perley D, Lefebvre F, Lepage P, Bourgey M, Bourque G, Ragoussis J, Mooser V, Taliun D. A cost-effective sequencing method for genetic studies combining high-depth whole exome and low-depth whole genome. NPJ Genom Med 2024; 9(1): 8.
- Bochenek ML, Saar K, Nazari-Jahantigh M, Gogiraju R, Wiedenroth CB, Munzel T, Mayer E, Fink L, Schober A, Hubner N, Guth S, Konstantinides S, Schafer K. Endothelial Overexpression of TGF-beta-Induced Protein Impairs Venous Thrombus Resolution: Possible Role in CTEPH. JACC Basic Transl Sci 2024; 9(1): 100-116.
- Chen W, Jin B, Cheng C, Peng H, Zhang X, Tan W, Tang R, Lian X, Diao H, Luo N, Li X, Fan J, Shi J, Yin C, Wang J, Peng S, Yu L, Li J, Wu RQ, Kuang DM, Shi GP, Zhou Y, Wang F, Jiang X. Single-cell profiling reveals kidney CD163(+) dendritic cell participation in human lupus nephritis. Ann Rheum Dis 2024.
- Christ A, Maas SL, Jin H, Lu C, Legein B, Wijnands E, Temmerman L, Otten J, Isaacs A, Zenke M, Stoll M, Biessen EAL, van der Vorst EPC. In situ lipid-loading activates peripheral dendritic cell subsets characterized by cellular ROS accumulation but compromises their capacity to prime naive T cells. Free Radic Biol Med 2024; 210: 406-415.
- Dong Y, Kang Z, Zhang Z, Zhang Y, Zhou H, Liu Y, Shuai X, Li J, Yin L, Wang X, Ma Y, Fan H, Jiang F, Lin Z, Ding C, Yun Jin K, Sarapultsev A, Li F, Zhang G, Xie T, Yin C, Cheng X, Luo S, Liu Y, Hu D. Single-cell profile reveals the landscape of cardiac immunity and identifies a cardio-protective Ym-1(hi) neutrophil in myocardial ischemia-reperfusion injury. Sci Bull (Beijing) 2024.
- Frenz-Wiessner S, Fairley SD, Buser M, Goek I, Salewskij K, Jonsson G, Illig D, Zu Putlitz B, Petersheim D, Li Y, Chen PH, Kalauz M, Conca R, Sterr M, Geuder J, Mizoguchi Y, Megens RTA, Linder MI, Kotlarz D, Rudelius M, Penninger JM, Marr C, Klein C. Generation of complex bone marrow organoids from human induced pluripotent stem cells. Nat Methods 2024.
- Guerra J, Matta L, Bartelt A. Cardiac proteostasis in obesity and cardiovascular disease. Herz 2024.
- Jia Y, Cheng L, Yang J, Mao J, Xie Y, Yang X, Zhang X, Wang D, Zhao Z, Schober A, Wei Y. miR-223-3p Prevents Necroptotic Macrophage Death by Targeting Ripk3 in a Negative Feedback Loop and Consequently Ameliorates Advanced Atherosclerosis. Arterioscler Thromb Vasc Biol 2024; 44(1): 218-237.
- Kosinski J, Sechi A, Hain J, Villwock S, Ha SA, Hauschulz M, Rose M, Steib F, Ortiz-Bruchle N, Heij L, Maas SL, van der Vorst EPC, Knoesel T, Altendorf-Hofmann A, Simon R, Sauter G, Bednarsch J, Jonigk D, Dahl E. ITIH5 as a multifaceted player in pancreatic cancer suppression, impairing tyrosine kinase signaling, cell adhesion and migration. Mol Oncol 2024.
- Lip GYH, Rigby A, Weber C. A Happy New Year 2024 from Thrombosis and Haemostasis! Thromb Haemost 2024; 124(1): 1-3.
- Samus M, Rot A. Atypical chemokine receptors in cancer. Cytokine 2024; 176: 156504.
- van der Vorst EPC, Kovacic JC. Therapeutic targeting of cell transition: ready for clinical prime-time? Cardiovasc Res 2024.
- Wang Y, Panicker IS, Anesi J, Sargisson O, Atchison B, Habenicht AJR. Animal Models, Pathogenesis, and Potential Treatment of Thoracic Aortic Aneurysm. Int J Mol Sci 2024; 25(2).
- Weber C, Rigby A, Lip GYH. Thrombosis and Haemostasis 2023 Editors' Choice Papers. Thromb Haemost 2024; 124(1): 80-87.
- Aghdassi A, Schwedhelm E, Atzler D, Nauck M, Kuhn JP, Kromrey ML, Volzke H, Felix SB, Dorr M, Ittermann T, Bahls M. The relationship between homoarginine and liver biomarkers: a combination of epidemiological and clinical studies. Sci Rep 2023; 13(1): 5230. https://www.ncbi.nlm.nih.gov/pubmed/36997574
- Baretella O, Buser L, Andres C, Haberli D, Lenz A, Doring Y, Baumgartner I, Schindewolf M. Association of sex and cardiovascular risk factors with atherosclerosis distribution pattern in lower extremity peripheral artery disease. Front Cardiovasc Med 2023; 10: 1004003. https://www.ncbi.nlm.nih.gov/pubmed/37441701
- Bazioti V, Halmos B, Westerterp M. T-cell Cholesterol Accumulation, Aging, and Atherosclerosis. Current Atherosclerosis Reports 2023; 25(9): 527-534. https://www.ncbi.nlm.nih.gov/pubmed/37395922
- Bianchini M, Moller-Ramon Z, Weber C, Megens RTA, Duchene J. Short-Term Western Diet Causes Rapid and Lasting Alterations of Bone Marrow Physiology. Thromb Haemost 2023; 123(11): 1100-1104. https://www.ncbi.nlm.nih.gov/pubmed/37549687
- Blanchet X, Weber C, von Hundelshausen P. Chemokine Heteromers and Their Impact on Cellular Function-A Conceptual Framework. Int J Mol Sci 2023; 24(13). https://www.ncbi.nlm.nih.gov/pubmed/37446102
- Bochenek ML, Saar K, Nazari-Jahantigh M, Gogiraju R, Wiedenroth CB, Münzel T, Mayer E, Fink L, Schober A, Hübner N, Guth S, Konstantinides S, Schäfer K. Endothelial Overexpression of TGF-β-Induced Protein Impairs Venous Thrombus Resolution. JACC: Basic to Translational Science Epub 2023. https://www.jacc.org/doi/abs/10.1016/j.jacbts.2023.08.005
- Bonfiglio CA, Weber C, Atzler D, Lutgens E. Immunotherapy and cardiovascular diseases: novel avenues for immunotherapeutic approaches. QJM 2023; 116(4): 271-278. https://www.ncbi.nlm.nih.gov/pubmed/34293177
- Bosmans LA, van Tiel CM, Aarts S, Willemsen L, Baardman J, van Os BW, Toom MD, Beckers L, Ahern DJ, Levels JHM, Jongejan A, Moerland PD, Verberk SGS, den Bossche JV, de Winther M, Weber C, Atzler D, Monaco C, Gerdes N, Shami A, Lutgens E. Myeloid CD40 deficiency reduces atherosclerosis by impairing macrophages' transition into a pro-inflammatory state. Cardiovasc Res 2023; 119(5): 1146-1160. https://www.ncbi.nlm.nih.gov/pubmed/35587037
- Christ A, Maas SL, Jin H, Lu C, Legein B, Wijnands E, Temmerman L, Otten J, Isaacs A, Zenke M, Stoll M, Biessen EAL, van der Vorst EPC. In situ lipid-loading activates peripheral dendritic cell subsets characterized by cellular ROS accumulation but compromises their capacity to prime naive T cells. Free Radic Biol Med 2024; 210: 406-415. https://www.ncbi.nlm.nih.gov/pubmed/38061606
- Briukhovetska D, Suarez-Gosalvez J, Voigt C, Markota A, Giannou AD, Schubel M, Jobst J, Zhang T, Dorr J, Markl F, Majed L, Muller PJ, May P, Gottschlich A, Tokarew N, Lucke J, Oner A, Schwerdtfeger M, Andreu-Sanz D, Grunmeier R, Seifert M, Michaelides S, Hristov M, Konig LM, Cadilha BL, Mikhaylov O, Anders HJ, Rothenfusser S, Flavell RA, Cerezo-Wallis D, Tejedo C, Soengas MS, Bald T, Huber S, Endres S, Kobold S. T cell-derived interleukin-22 drives the expression of CD155 by cancer cells to suppress NK cell function and promote metastasis. Immunity 2023; 56(1): 143-161 e111. https://www.ncbi.nlm.nih.gov/pubmed/36630913
- Brunetta HS, Jung AS, Francisco A, Castilho RF, Mori MA, Bartelt A. IF1 controls UCP1-dependent mitochondrial bioenergetics in brown adipocytes. bioRxiv 2023: 2023.2007.2027.550888. https://www.biorxiv.org/content/biorxiv/early/2023/07/27/2023.07.27.550888.full.pdf
- Cimen I, Natarelli L, Abedi Kichi Z, Henderson JM, Farina FM, Briem E, Aslani M, Megens RTA, Jansen Y, Mann-Fallenbuchel E, Gencer S, Duchene J, Nazari-Jahantigh M, van der Vorst EPC, Enard W, Doring Y, Schober A, Santovito D, Weber C. Targeting a cell-specific microRNA repressor of CXCR4 ameliorates atherosclerosis in mice. Sci Transl Med 2023; 15(720): eadf3357. https://www.ncbi.nlm.nih.gov/pubmed/37910599
- de Winther MPJ, Back M, Evans P, Gomez D, Goncalves I, Jorgensen HF, Koenen RR, Lutgens E, Norata GD, Osto E, Dib L, Simons M, Stellos K, Yla-Herttuala S, Winkels H, Bochaton-Piallat ML, Monaco C. Translational opportunities of single-cell biology in atherosclerosis. Eur Heart J 2023; 44(14): 1216-1230. https://www.ncbi.nlm.nih.gov/pubmed/36478058
- Duan R, Ni Q, Li Y, Zhu M, Li W, Wang P, Yuan K, von Hundelshausen P, Zhu J, Zhang L, Lv L. Lymphocytes, Mean Platelet Volume, and Albumin in Critically Ill COVID-19 Patients with Venous Thromboembolism. Clin Appl Thromb Hemost 2023; 29: 10760296231177676. https://www.ncbi.nlm.nih.gov/pubmed/37229645
- Ebert S, Zang L, Ismail N, Otabil M, Frohlich A, Egea V, Acs S, Hoeberg M, Berres ML, Weber C, Moreira JMA, Ries C, Bernhagen J, El Bounkari O. Tissue Inhibitor of Metalloproteinases-1 Interacts with CD74 to Promote AKT Signaling, Monocyte Recruitment Responses, and Vascular Smooth Muscle Cell Proliferation. Cells 2023; 12(14). https://www.ncbi.nlm.nih.gov/pubmed/37508563
- Egea V, Megens RTA, Santovito D, Wantha S, Brandl R, Siess W, Khani S, Soehnlein O, Bartelt A, Weber C, Ries C. Properties and fate of human mesenchymal stem cells upon miRNA let-7f-promoted recruitment to atherosclerotic plaques. Cardiovasc Res 2023; 119(1): 155-166. https://www.ncbi.nlm.nih.gov/pubmed/35238350
- Farina FM, Weber C, Santovito D. The emerging landscape of non-conventional RNA functions in atherosclerosis. Atherosclerosis 2023; 374: 74-86. https://www.ncbi.nlm.nih.gov/pubmed/36725418
- Ferraro B, Giustetto P, Schengel O, Weckbach LT, Maegdefessel L, Soehnlein O. Longitudinal In Vivo Monitoring of Atheroprogression in Hypercholesterolemic Mice Using Photoacoustic Imaging. Thromb Haemost 2023; 123(5): 545-554. https://www.ncbi.nlm.nih.gov/pubmed/36596447
- Gatsiou A, Tual-Chalot S, Napoli M, Ortega-Gomez A, Regen T, Badolia R, Cesarini V, Garcia-Gonzalez C, Chevre R, Ciliberti G, Silvestre-Roig C, Martini M, Hoffmann J, Hamouche R, Visker JR, Diakos N, Wietelmann A, Silvestris DA, Georgiopoulos G, Moshfegh A, Schneider A, Chen W, Guenther S, Backs J, Kwak S, Selzman CH, Stamatelopoulos K, Rose-John S, Trautwein C, Spyridopoulos I, Braun T, Waisman A, Gallo A, Drakos SG, Dimmeler S, Sperandio M, Soehnlein O, Stellos K. The RNA editor ADAR2 promotes immune cell trafficking by enhancing endothelial responses to interleukin-6 during sterile inflammation. Immunity 2023; 56(5): 979-997 e911. https://www.ncbi.nlm.nih.gov/pubmed/37100060
- Gencer S, van der Vorst EPC. Role of G-Protein-Coupled Receptors in Cardiovascular Diseases. Int J Mol Sci 2023; 24(9). https://www.ncbi.nlm.nih.gov/pubmed/37175466
- Ghiboub M, Bell M, Sinkeviciute D, Prinjha RK, de Winther MPJ, Harker NR, Tough DF, de Jonge WJ. The Epigenetic Reader Protein SP140 Regulates Dendritic Cell Activation, Maturation and Tolerogenic Potential. Curr Issues Mol Biol 2023; 45(5): 4228-4245. https://www.ncbi.nlm.nih.gov/pubmed/37232738
- Gigante B, Levy JH, van Gorp E, Bartoloni A, Bochaton-Piallat ML, Back M, Ten Cate H, Christersson C, Ferreiro JL, Geisler T, Lutgens E, Schulman S, Storey RF, Thachil J, Vilahur G, Liaw PC, Rocca B. Management of patients on antithrombotic therapy with severe infections: a joint clinical consensus statement of the ESC Working Group on Thrombosis, the ESC Working Group on Atherosclerosis and Vascular Biology, and the International Society on Thrombosis and Haemostasis. Eur Heart J 2023; 44(32): 3040-3058. https://www.ncbi.nlm.nih.gov/pubmed/37439553
- Giroud M, Kotschi S, Kwon Y, Le Thuc O, Hoffmann A, Gil-Lozano M, Karbiener M, Higareda-Almaraz JC, Khani S, Tews D, Fischer-Posovszky P, Sun W, Dong H, Ghosh A, Wolfrum C, Wabitsch M, Virtanen KA, Bluher M, Nielsen S, Zeigerer A, Garcia-Caceres C, Scheideler M, Herzig S, Bartelt A. The obesity-linked human lncRNA AATBC stimulates mitochondrial function in adipocytes. EMBO Rep 2023; 24(10): e57600. https://www.ncbi.nlm.nih.gov/pubmed/37671834
- Gomez AM, Bartelt A. Endocrine communication of endoplasmic reticulum stress. Bioessays 2023; 45(8): e2300093. https://www.ncbi.nlm.nih.gov/pubmed/37318317
- Gyongyosi M, Alcaide P, Asselbergs FW, Brundel B, Camici GG, Martins PDC, Ferdinandy P, Fontana M, Girao H, Gnecchi M, Gollmann-Tepekoylu C, Kleinbongard P, Krieg T, Madonna R, Paillard M, Pantazis A, Perrino C, Pesce M, Schiattarella GG, Sluijter JPG, Steffens S, Tschope C, Van Linthout S, Davidson SM. Long COVID and the cardiovascular system-elucidating causes and cellular mechanisms in order to develop targeted diagnostic and therapeutic strategies: a joint Scientific Statement of the ESC Working Groups on Cellular Biology of the Heart and Myocardial and Pericardial Diseases. Cardiovasc Res 2023; 119(2): 336-356. https://www.ncbi.nlm.nih.gov/pubmed/35875883
- Imamdin A, van der Vorst EPC. Exploring the Role of Serotonin as an Immune Modulatory Component in Cardiovascular Diseases. Int J Mol Sci 2023; 24(2). https://www.ncbi.nlm.nih.gov/pubmed/36675065
- Kocberber Z, Willemsen N, Bartelt A. The role of proteasome activators PA28alphabeta and PA200 in brown adipocyte differentiation and function. Front Endocrinol (Lausanne) 2023; 14: 1176733. https://www.ncbi.nlm.nih.gov/pubmed/37201100
- Kopp EL, Deussen DN, Cuomo R, Lorenz R, Roth DM, Mahata SK, Patel HH. Modeling and Phenotyping Acute and Chronic Type 2 Diabetes Mellitus In Vitro in Rodent Heart and Skeletal Muscle Cells. Cells 2023; 12(24). https://www.ncbi.nlm.nih.gov/pubmed/38132105
- Kral M, van der Vorst EPC, Surnov A, Weber C, Doring Y. ILC2-mediated immune crosstalk in chronic (vascular) inflammation. Front Immunol 2023; 14: 1326440. https://www.ncbi.nlm.nih.gov/pubmed/38179045
- Krammer C, Yang B, Reichl S, Besson-Girard S, Ji H, Bolini V, Schulte C, Noels H, Schlepckow K, Jocher G, Werner G, Willem M, El Bounkari O, Kapurniotu A, Gokce O, Weber C, Mohanta S, Bernhagen J. Pathways linking aging and atheroprotection in Mif-deficient atherosclerotic mice. FASEB J 2023; 37(3): e22752. https://www.ncbi.nlm.nih.gov/pubmed/36794636
- Leberzammer J, von Hundelshausen P. Chemokines, molecular drivers of thromboinflammation and immunothrombosis. Front Immunol 2023; 14: 1276353. https://www.ncbi.nlm.nih.gov/pubmed/37954596
- Lemmer IL, Bartelt A. Brown fat has a sweet tooth. Nat Metab 2023; 5(7): 1080-1081. https://www.ncbi.nlm.nih.gov/pubmed/37337121
- Lemmer IL, Haas DT, Willemsen N, Kotschi S, Toksöz I, Gjika E, Khani S, Rohm M, Diercksen N, Nguyen PBH, Menden MP, Egu DT, Waschke J, Larsen S, Ma T, Gerhart-Hines Z, Herzig S, Dyar K, Krahmer N, Bartelt A. Nfe2l1-mediated proteasome function controls muscle energy metabolism in obesity. bioRxiv 2023: 2023.2004.2020.537611. https://www.biorxiv.org/content/biorxiv/early/2023/05/15/2023.04.20.537611.full.pdf
- Lin C, Mostafa A, Jans A, Wolters JC, Mohamed MR, Van der Vorst EPC, Trautwein C, Bartneck M. Targeting Ligand Independent Tropism of siRNA-LNP by Small Molecules for Directed Therapy of Liver or Myeloid Immune Cells. Adv Healthc Mater 2023: e2202670. https://www.ncbi.nlm.nih.gov/pubmed/36617516
- Lip GYH, Rigby A, Weber C. A Happy New Year 2023 from Thrombosis and Haemostasis. Thromb Haemost 2023; 123(1): 1-5. https://www.ncbi.nlm.nih.gov/pubmed/36626897
- Louradour J, Ottersberg R, Segiser A, Olejnik A, Martinez-Salazar B, Siegrist M, Egle M, Barbieri M, Nimani S, Alerni N, Doring Y, Odening KE, Longnus S. Simultaneous assessment of mechanical and electrical function in Langendorff-perfused ex-vivo mouse hearts. Front Cardiovasc Med 2023; 10: 1293032. https://www.ncbi.nlm.nih.gov/pubmed/38028448
- Maas SL, Donners M, van der Vorst EPC. ADAM10 and ADAM17, Major Regulators of Chronic Kidney Disease Induced Atherosclerosis? Int J Mol Sci 2023; 24(8). https://www.ncbi.nlm.nih.gov/pubmed/37108478
- Maas SL, Megens RTA, van der Vorst EPC. Ex Vivo Perfusion System to Analyze Chemokine-Driven Leukocyte Adhesion. Methods Mol Biol 2023; 2597: 59-75. https://www.ncbi.nlm.nih.gov/pubmed/36374414
- Maas SL, van der Vorst EPC. In Vitro (Trans)Migration Experiment Using Chemokines as Stimulatory Factor. Methods Mol Biol 2023; 2597: 77-87. https://www.ncbi.nlm.nih.gov/pubmed/36374415
- Matta L, Blaas L, de Faria CC. From honeymoon to dysfunction: brown fat remodelling in obesity. J Physiol 2023; 601(4): 711-713. https://www.ncbi.nlm.nih.gov/pubmed/36617494
- Matta L, Breves C, Fonte Boa L, Domingos AE, Faria CC, Souza I, Correia Lima-Junior N, Rocha APT, Gregorio BM, Carvalho DP, Ferreira ACF, Nascimento JHM, Maciel L, Fortunato RS. Quercetin improves white adipose tissue redox homeostasis in ovariectomized rats. J Endocrinol 2023; 259(2). https://www.ncbi.nlm.nih.gov/pubmed/37566237
- Melgrati S, Radice E, Ameti R, Hub E, Thelen S, Pelczar P, Jarrossay D, Rot A, Thelen M. Atlas of the anatomical localization of atypical chemokine receptors in healthy mice. PLoS Biol 2023; 21(5): e3002111. https://www.ncbi.nlm.nih.gov/pubmed/37159457
- Mena Gómez A, Bartelt A. Live lean and CRISPR – Engineering metabolism with FGF21 and FNDC5. Clinical and Translational Discovery 2023; 3(5): e230. https://onlinelibrary.wiley.com/doi/abs/10.1002/ctd2.230
- Mohanta SK, Sun T, Lu S, Wang Z, Zhang X, Yin C, Weber C, Habenicht AJR. The Impact of the Nervous System on Arteries and the Heart: The Neuroimmune Cardiovascular Circuit Hypothesis. Cells 2023; 12(20). https://www.ncbi.nlm.nih.gov/pubmed/37887328
- Mohanta SK, Yin C, Weber C, Godinho-Silva C, Veiga-Fernandes H, Xu QJ, Chang RB, Habenicht AJR. Cardiovascular Brain Circuits. Circ Res 2023; 132(11): 1546-1565. https://www.ncbi.nlm.nih.gov/pubmed/37228235
- Mohanta SK, Yin C, Weber C, Habenicht AJR. Neuroimmune cardiovascular interfaces in atherosclerosis. Front Cell Dev Biol 2023; 11: 1117368. https://www.ncbi.nlm.nih.gov/pubmed/36793445
- Naeimzadeh Y, Ilbeigi S, Dastsooz H, Rafiee Monjezi M, Mansoori Y, Tabei SMB. Protooncogenic Role of ARHGAP11A and ARHGAP11B in Invasive Ductal Carcinoma: Two Promising Breast Cancer Biomarkers. Biomed Res Int 2023; 2023: 8236853. https://www.ncbi.nlm.nih.gov/pubmed/38046902
- Nording H, Baron L, Sauter M, Lubken A, Rawish E, Szepanowski R, von Esebeck J, Sun Y, Emami H, Meusel M, Saraei R, Schanze N, Gorantla SP, von Bubnoff N, Geisler T, von Hundelshausen P, Stellos K, Marquardt J, Sadik CD, Kohl J, Duerschmied D, Kleinschnitz C, Langer HF. Platelets regulate ischemia-induced revascularization and angiogenesis by secretion of growth factor-modulating factors. Blood Adv 2023; 7(21): 6411-6427. https://www.ncbi.nlm.nih.gov/pubmed/37257194
- Ofoghi A, Kotschi S, Lemmer IL, Haas DT, Willemsen N, Bayer B, Möller S, Haberecht-Müller S, Krüger E, Krahmer N, Bartelt A. Activating the NFE2L1-ubiquitin-proteasome system by DDI2 protects from ferroptosis. bioRxiv 2023: 2023.2007.2004.547652. https://www.biorxiv.org/content/biorxiv/early/2023/07/04/2023.07.04.547652.full.pdf
- Pan C, Herrero-Fernandez B, Borja Almarcha C, Gomez Bris R, Zorita V, Saez A, Maas SL, Perez-Olivares L, Herrero-Cervera A, Lemnitzer P, van Avondt K, Silvestre-Roig C, Gonzalez-Granado JM, Chevre R, Soehnlein O. Time-Restricted Feeding Enhances Early Atherosclerosis in Hypercholesterolemic Mice. Circulation 2023; 147(9): 774-777. https://www.ncbi.nlm.nih.gov/pubmed/36848415
- Pappritz K, Puhl SL, Matz I, Brauer E, Shia YX, El-Shafeey M, Koch SE, Miteva K, Mucha C, Duda GN, Petersen A, Steffens S, Tschope C, Van Linthout S. Sex- and age-related differences in the inflammatory properties of cardiac fibroblasts: impact on the cardiosplenic axis and cardiac fibrosis. Front Cardiovasc Med 2023; 10: 1117419. https://www.ncbi.nlm.nih.gov/pubmed/38054090
- Pavlic A, Poelman H, Wasilewski G, Wichapong K, Lux P, Maassen C, Lutgens E, Schurgers LJ, Reutelingsperger CP, Nicolaes GAF. Inhibition of Neutral Sphingomyelinase 2 by Novel Small Molecule Inhibitors Results in Decreased Release of Extracellular Vesicles by Vascular Smooth Muscle Cells and Attenuated Calcification. Int J Mol Sci 2023; 24(3). https://www.ncbi.nlm.nih.gov/pubmed/36768348
- Pekayvaz K, Gold C, Hoseinpour P, Engel A, Martinez-Navarro A, Eivers L, Coletti R, Joppich M, Dionisio F, Kaiser R, Tomas L, Janjic A, Knott M, Mehari F, Polewka V, Kirschner M, Boda A, Nicolai L, Schulz H, Titova A, Kilani B, Lorenz M, Fingerle-Rowson G, Bucala R, Enard W, Zimmer R, Weber C, Libby P, Schulz C, Massberg S, Stark K. Mural cell-derived chemokines provide a protective niche to safeguard vascular macrophages and limit chronic inflammation. Immunity 2023; 56(10): 2325-2341 e2315. https://www.ncbi.nlm.nih.gov/pubmed/37652021
- Petrick HL, Pinckaers PJM, Brunetta HS. Ketone body oxidation: glycogen-sparing yet glucose-dependent? J Physiol 2023; 601(12): 2237-2239. https://www.ncbi.nlm.nih.gov/pubmed/37070238
- Rakateli L, Huchzermeier R, van der Vorst EPC. AhR, PXR and CAR: From Xenobiotic Receptors to Metabolic Sensors. Cells 2023; 12(23). https://www.ncbi.nlm.nih.gov/pubmed/38067179
- Rega S, Farina F, Bouhuis S, de Donato S, Chiesa M, Poggio P, Cavallotti L, Bonalumi G, Giambuzzi I, Pompilio G, Perrucci GL. Multi-omics in thoracic aortic aneurysm: the complex road to the simplification. Cell Biosci 2023; 13(1): 131. https://www.ncbi.nlm.nih.gov/pubmed/37475058
- Reiche ME, Poels K, Bosmans LA, Vos WG, Van Tiel CM, Gijbels MJJ, Aarts S, Den Toom M, Beckers L, Weber C, Atzler D, Rensen PCN, Kooijman S, Lutgens E. Adipocytes control hematopoiesis and inflammation through CD40 signaling. Haematologica 2023; 108(7): 1873-1885. https://www.ncbi.nlm.nih.gov/pubmed/36475519
- Ren L, Li F, Tan X, Fan Y, Ke B, Zhang Y, Jiang H, Jia L, Wang Y, Du J. Abnormal plasma ceramides refine high-risk patients with worsening heart failure. Front Cardiovasc Med 2023; 10: 1185595. https://www.ncbi.nlm.nih.gov/pubmed/37456812
- Sachs S, Gotz A, Finan B, Feuchtinger A, DiMarchi RD, Doring Y, Weber C, Tschop MH, Muller TD, Hofmann SM. GIP receptor agonism improves dyslipidemia and atherosclerosis independently of body weight loss in preclinical mouse model for cardio-metabolic disease. Cardiovasc Diabetol 2023; 22(1): 217. https://www.ncbi.nlm.nih.gov/pubmed/37592302
- Santovito D, Fan Y, Elia L, Tan JTM, van der Vorst EPC. Editorial: Emerging roles of miRNAs in cardiovascular disease. Front Cardiovasc Med 2023; 10: 1144849. https://www.ncbi.nlm.nih.gov/pubmed/36926041
- Santovito D, Steffens S, Barachini S, Madonna R. Autophagy, innate immunity, and cardiac disease. Front Cell Dev Biol 2023; 11: 1149409. https://www.ncbi.nlm.nih.gov/pubmed/37234771
- Schonichen C, Montague SJ, Brouns SLN, Burston JJ, Cosemans J, Jurk K, Kehrel BE, Koenen RR, Ni Ainle F, O'Donnell VB, Soehnlein O, Watson SP, Kuijpers MJE, Heemskerk JWM, Nagy M. Antagonistic Roles of Human Platelet Integrin alphaIIbbeta3 and Chemokines in Regulating Neutrophil Activation and Fate on Arterial Thrombi Under Flow. Arterioscler Thromb Vasc Biol 2023; 43(9): 1700-1712. https://www.ncbi.nlm.nih.gov/pubmed/37409530
- Soehnlein O, Doring Y. Beyond association: high neutrophil counts are a causal risk factor for atherosclerotic cardiovascular disease. Eur Heart J 2023; 44(47): 4965-4967. https://www.ncbi.nlm.nih.gov/pubmed/37981833
- Steffens S, Schroder K, Kruger M, Maack C, Streckfuss-Bomeke K, Backs J, Backofen R, Baessler B, Devaux Y, Gilsbach R, Heijman J, Knaus J, Kramann R, Linz D, Lister AL, Maatz H, Maegdefessel L, Mayr M, Meder B, Nussbeck SY, Rog-Zielinska EA, Schulz MH, Sickmann A, Yigit G, Kohl P. The challenges of research data management in cardiovascular science: a DGK and DZHK position paper-executive summary. Clin Res Cardiol 2023. https://www.ncbi.nlm.nih.gov/pubmed/37847314
- Sun J, Singh P, Shami A, Kluza E, Pan M, Djordjevic D, Michaelsen NB, Kennback C, van der Wel NN, Orho-Melander M, Nilsson J, Formentini I, Conde-Knape K, Lutgens E, Edsfeldt A, Goncalves I. Spatial Transcriptional Mapping Reveals Site-Specific Pathways Underlying Human Atherosclerotic Plaque Rupture. J Am Coll Cardiol 2023; 81(23): 2213-2227. https://www.ncbi.nlm.nih.gov/pubmed/37286250
- Tahamtan A, Samadizadeh S, Salimi V, Natarelli L, Nakstad B. Editorial: miRNAs and inflammation: from biogenesis to therapeutic option. Front Immunol 2023; 14: 1296589. https://www.ncbi.nlm.nih.gov/pubmed/37854607
- Thakur M, Junho CVC, Bernhard SM, Schindewolf M, Noels H, Doring Y. NETs-Induced Thrombosis Impacts on Cardiovascular and Chronic Kidney Disease. Circ Res 2023; 132(8): 933-949. https://www.ncbi.nlm.nih.gov/pubmed/37053273
- Tufanli O, Citir M, Yin C, Van der Vorst EPC, Cimen I. Editorial: The connections of immune metabolic mechanisms with aging-related diseases. Front Cell Dev Biol 2023; 11: 1295264. https://www.ncbi.nlm.nih.gov/pubmed/37829186
- Tuleja A, Bernhard S, Hamvas G, Andreoti TA, Rossler J, Boon L, Vikkula M, Kammer R, Haupt F, Doring Y, Baumgartner I. Clinical phenotype of adolescent and adult patients with extracranial vascular malformation. J Vasc Surg Venous Lymphat Disord 2023; 11(5): 1034-1044 e1033. https://www.ncbi.nlm.nih.gov/pubmed/37030445
- van der Vorst EPC, Badimon L. The unknown functions of a known protein: the case of coagulation factor XI. Cardiovasc Res 2023; 119(7): e137-e139. https://www.ncbi.nlm.nih.gov/pubmed/37141257
- van der Vorst EPC, Maas SL, Theodorou K, Peters LJF, Jin H, Rademakers T, Gijbels MJ, Rousch M, Jansen Y, Weber C, Lehrke M, Lebherz C, Yildiz D, Ludwig A, Bentzon JF, Biessen EAL, Donners M. Endothelial ADAM10 controls cellular response to oxLDL and its deficiency exacerbates atherosclerosis with intraplaque hemorrhage and neovascularization in mice. Front Cardiovasc Med 2023; 10: 974918. https://www.ncbi.nlm.nih.gov/pubmed/36776254
- van Os BW, Kusters PJH, den Toom M, Beckers L, van Tiel CM, Vos WG, de Jong E, Kieser A, van Roomen C, Binder CJ, Reiche ME, de Winther MP, Bosmans LA, Lutgens E. Deficiency of germinal center kinase TRAF2 and NCK-interacting kinase (TNIK) in B cells does not affect atherosclerosis. Front Cardiovasc Med 2023; 10: 1171764. https://www.ncbi.nlm.nih.gov/pubmed/37215541
- van Os BW, Vos WG, Bosmans LA, van Tiel CM, Lith SC, den Toom MS, Beckers L, Levels JHM, van Wouw SAE, Zelcer N, Zaal EA, Berkers CR, van der Lest CHA, Helms JB, Weber C, Atzler D, de Winther MPJ, Baardman J, Lutgens E. Hyperlipidaemia elicits an atypical, T helper 1-like CD4(+) T-cell response: a key role for very low-density lipoprotein. Eur Heart J Open 2023; 3(2): oead013. https://www.ncbi.nlm.nih.gov/pubmed/36969380
- van Os BW, Vos WG, Bosmans LA, van Tiel CM, Toom MD, Beckers L, Admiraal M, Hoeksema MA, de Winther MP, Lutgens E. CD40L modulates CD4(+) T-cell activation through receptor for activated C kinase 1. Eur J Immunol 2023; 53(12): e2350520. https://www.ncbi.nlm.nih.gov/pubmed/37683186
- Wagner JUG, Tombor LS, Malacarne PF, Kettenhausen LM, Panthel J, Kujundzic H, Manickam N, Schmitz K, Cipca M, Stilz KA, Fischer A, Muhly-Reinholz M, Abplanalp WT, John D, Mohanta SK, Weber C, Habenicht AJR, Buchmann GK, Angendohr S, Amin E, Scherschel K, Klocker N, Kelm M, Schuttler D, Clauss S, Gunther S, Boettger T, Braun T, Bar C, Pham MD, Krishnan J, Hille S, Muller OJ, Bozoglu T, Kupatt C, Nardini E, Osmanagic-Myers S, Meyer C, Zeiher AM, Brandes RP, Luxan G, Dimmeler S. Aging impairs the neurovascular interface in the heart. Science 2023; 381(6660): 897-906. https://www.ncbi.nlm.nih.gov/pubmed/37616346
- Wang HF, Wang YX, Zhou YP, Wei YP, Yan Y, Zhang ZJ, Jing ZC. Protein O-GlcNAcylation in cardiovascular diseases. Acta Pharmacol Sin 2023; 44(1): 8-18. https://www.ncbi.nlm.nih.gov/pubmed/35817809
- Wang Z, Zhang X, Lu S, Zhang C, Ma Z, Su R, Li Y, Sun T, Li Y, Hong M, Deng X, Monjezi MR, Hristov M, Steffens S, Santovito D, Dornmair K, Ley K, Weber C, Mohanta SK, Habenicht AJR, Yin C. Pairing of single-cell RNA analysis and T cell antigen receptor profiling indicates breakdown of T cell tolerance checkpoints in atherosclerosis. Nat Cardiovasc Res 2023; 2(3): 290-306. https://www.ncbi.nlm.nih.gov/pubmed/37621765
- Weber C, Blanchet X, Lip GYH. Thrombosis and Haemostasis 2022 Editors' Choice Papers. Thromb Haemost 2023; 123(1): 123-130. https://www.ncbi.nlm.nih.gov/pubmed/36626900
- Weber C, Habenicht AJR, von Hundelshausen P. Novel mechanisms and therapeutic targets in atherosclerosis: inflammation and beyond. Eur Heart J 2023; 44(29): 2672-2681. https://www.ncbi.nlm.nih.gov/pubmed/37210082
- Xiao X, Deng X, Zhang G, Liu M, Fu D, Yang P, Li X, Jiang H. Monitoring of the regulatory ability and regulatory state of the autonomic nervous system and its application to the management of hypertensive patients: a study protocol for randomised controlled trials. BMJ Open 2023; 13(6): e063434. https://www.ncbi.nlm.nih.gov/pubmed/37286315
- Yerly A, van der Vorst EPC, Baumgartner I, Bernhard SM, Schindewolf M, Doring Y. Sex-specific and hormone-related differences in vascular remodelling in atherosclerosis. Eur J Clin Invest 2023; 53(1): e13885. https://www.ncbi.nlm.nih.gov/pubmed/36219492
- Ying Z, van Eenige R, Beerepoot R, Boon MR, Kloosterhuis NJ, van de Sluis B, Bartelt A, Rensen PCN, Kooijman S. Mirabegron-induced brown fat activation does not exacerbate atherosclerosis in mice with a functional hepatic ApoE-LDLR pathway. Pharmacol Res 2023; 187: 106634. https://www.ncbi.nlm.nih.gov/pubmed/36574856
- Zhou Y, Schober A. The Year of miR-223: How Platelets Can Kill Cardiomyocytes. Arterioscler Thromb Vasc Biol 2023; 43(2): 231-233. https://www.ncbi.nlm.nih.gov/pubmed/36579642
- Ziegler KA, Ahles A, Dueck A, Esfandyari D, Pichler P, Weber K, Kotschi S, Bartelt A, Sinicina I, Graw M, Leonhardt H, Weckbach LT, Massberg S, Schifferer M, Simons M, Hoeher L, Luo J, Erturk A, Schiattarella GG, Sassi Y, Misgeld T, Engelhardt S. Immune-mediated denervation of the pineal gland underlies sleep disturbance in cardiac disease. Science 2023; 381(6655): 285-290. https://www.ncbi.nlm.nih.gov/pubmed/37471539
- Asare Y, Shnipova M, Zivkovic L, Schlegl C, Tosato F, Aronova A, Brandhofer M, Strohm L, Beaufort N, Malik R, Weber C, Bernhagen J, Dichgans M. IKKbeta binds NLRP3 providing a shortcut to inflammasome activation for rapid immune responses. Signal Transduct Target Ther 2022; 7(1): 355. https://www.ncbi.nlm.nih.gov/pubmed/36257930
- Bazioti V, La Rose AM, Maassen S, Bianchi F, de Boer R, Halmos B, Dabral D, Guilbaud E, Flohr-Svendsen A, Groenen AG, Marmolejo-Garza A, Koster MH, Kloosterhuis NJ, Havinga R, Pranger AT, Langelaar-Makkinje M, de Bruin A, van de Sluis B, Kohan AB, Yvan-Charvet L, van den Bogaart G, Westerterp M. T cell cholesterol efflux suppresses apoptosis and senescence and increases atherosclerosis in middle aged mice. Nat Commun 2022; 13(1): 3799. https://www.ncbi.nlm.nih.gov/pubmed/35778407
- Bernhard SM, Adam L, Atef H, Haberli D, Bramer WM, Minder B, Doring Y, Laine JE, Muka T, Rossler J, Baumgartner I. A systematic review of the safety and efficacy of currently used treatment modalities in the treatment of patients with PIK3CA-related overgrowth spectrum. J Vasc Surg Venous Lymphat Disord 2022; 10(2): 527-538 e522. https://www.ncbi.nlm.nih.gov/pubmed/34358672
- Bozoglu T, Lee S, Ziegler T, Jurisch V, Maas S, Baehr A, Hinkel R, Hoenig A, Hariharan A, Kim CI, Decker S, Sami H, Koppara T, Oellinger R, Muller OJ, Frank D, Megens R, Nelson P, Weber C, Schnieke A, Sperandio M, Santamaria G, Rad R, Moretti A, Laugwitz KL, Soehnlein O, Ogris M, Kupatt C. Endothelial Retargeting of AAV9 In Vivo. Adv Sci (Weinh) 2022; 9(7): e2103867. https://www.ncbi.nlm.nih.gov/pubmed/35023328
- Brandhofer M, Hoffmann A, Blanchet X, Siminkovitch E, Rohlfing AK, El Bounkari O, Nestele JA, Bild A, Kontos C, Hille K, Rohde V, Frohlich A, Golemi J, Gokce O, Krammer C, Scheiermann P, Tsilimparis N, Sachs N, Kempf WE, Maegdefessel L, Otabil MK, Megens RTA, Ippel H, Koenen RR, Luo J, Engelmann B, Mayo KH, Gawaz M, Kapurniotu A, Weber C, von Hundelshausen P, Bernhagen J. Heterocomplexes between the atypical chemokine MIF and the CXC-motif chemokine CXCL4L1 regulate inflammation and thrombus formation. Cell Mol Life Sci 2022; 79(10): 512. https://www.ncbi.nlm.nih.gov/pubmed/36094626
- Carai P, Papageorgiou AP, Van Linthout S, Deckx S, Velthuis S, Lutgens E, Wijnands E, Tschope C, Schmuttermaier C, Kzhyshkowska J, Jones EAV, Heymans S. Stabilin-1 mediates beneficial monocyte recruitment and tolerogenic macrophage programming during CVB3-induced viral myocarditis. J Mol Cell Cardiol 2022; 165: 31-39. https://www.ncbi.nlm.nih.gov/pubmed/34968453
- Daugherty A, Hegele RA, Lu HS, Mackman N, Rader DJ, Weber C. Web of Science's Citation Median Metrics Overcome the Major Constraints of the Journal Impact Factor. Arterioscler Thromb Vasc Biol 2022; 42(4): 367-371. https://www.ncbi.nlm.nih.gov/pubmed/35109675
- Evans BR, Yerly A, van der Vorst EPC, Baumgartner I, Bernhard SM, Schindewolf M, Doring Y. Inflammatory Mediators in Atherosclerotic Vascular Remodeling. Front Cardiovasc Med 2022; 9: 868934. https://www.ncbi.nlm.nih.gov/pubmed/35600479
- Evans PC, Davidson SM, Wojta J, Back M, Bollini S, Brittan M, Catapano AL, Chaudhry B, Cluitmans M, Gnecchi M, Guzik TJ, Hoefer I, Madonna R, Monteiro JP, Morawietz H, Osto E, Padro T, Sluimer JC, Tocchetti CG, Van der Heiden K, Vilahur G, Waltenberger J, Weber C. From novel discovery tools and biomarkers to precision medicine-basic cardiovascular science highlights of 2021/22. Cardiovasc Res 2022; 118(13): 2754-2767. https://www.ncbi.nlm.nih.gov/pubmed/35899362
- Farina FM, Santovito D, Weber C. Two-Faced Janus: CCR2-Expressing Macrophages and Their Dual Role in Allograft Rejection of the Transplanted Heart. Circulation 2022; 146(8): 639-642. https://www.ncbi.nlm.nih.gov/pubmed/35994560
- Farina FM, Serio S, Hall IF, Zani S, Cassanmagnago GA, Climent M, Civilini E, Condorelli G, Quintavalle M, Elia L. The epigenetic enzyme DOT1L orchestrates vascular smooth muscle cell-monocyte crosstalk and protects against atherosclerosis via the NF-kappaB pathway. Eur Heart J 2022; 43(43): 4562-4576. https://www.ncbi.nlm.nih.gov/pubmed/35292818
- Faussner A, Deininger MM, Weber C, Steffens S. Direct addition of poly-lysine or poly-ethylenimine to the medium: A simple alternative to plate pre-coating. PLoS One 2022; 17(7): e0260173. https://www.ncbi.nlm.nih.gov/pubmed/35802710
- Ferdinandy P, Koller A, Weber C, Wojta J, Waltenberger J. Frontiers in CardioVascular Biomedicine (FCVB) 2022 Budapest is on in person! The excellent programme proves that scientists won against COVID-19. Cardiovasc Res 2022; 118(8): e59-e61. https://www.ncbi.nlm.nih.gov/pubmed/35438746
- Friess MC, Kritikos I, Schineis P, Medina-Sanchez JD, Gkountidi AO, Vallone A, Sigmund EC, Schwitter C, Vranova M, Matti C, Arasa J, Saygili Demir C, Bovay E, Proulx ST, Tomura M, Rot A, Legler DF, Petrova TV, Halin C. Mechanosensitive ACKR4 scavenges CCR7 chemokines to facilitate T cell de-adhesion and passive transport by flow in inflamed afferent lymphatics. Cell Rep 2022; 38(5): 110334. https://www.ncbi.nlm.nih.gov/pubmed/35108538
- Ganesh N, van der Vorst EPC, Spiesshofer J, He S, Burgmaier M, Findeisen H, Lehrke M, Swirski FK, Marx N, Kahles F. Gut immune cells-A novel therapeutical target for cardiovascular disease? Front Cardiovasc Med 2022; 9: 943214. https://www.ncbi.nlm.nih.gov/pubmed/36046186
- Gencer S, Doring Y, Jansen Y, Bayasgalan S, Yan Y, Bianchini M, Cimen I, Muller M, Peters LJF, Megens RTA, von Hundelshausen P, Duchene J, Lemnitzer P, Soehnlein O, Weber C, van der Vorst EPC. Endothelial ACKR3 drives atherosclerosis by promoting immune cell adhesion to vascular endothelium. Basic Res Cardiol 2022; 117(1): 30. https://www.ncbi.nlm.nih.gov/pubmed/35674847
- Georgakis MK, Bernhagen J, Heitman LH, Weber C, Dichgans M. Targeting the CCL2-CCR2 axis for atheroprotection. Eur Heart J 2022; 43(19): 1799-1808. https://www.ncbi.nlm.nih.gov/pubmed/35567558
- Giroud M, Jodeleit H, Prentice KJ, Bartelt A. Adipocyte function and the development of cardiometabolic disease. J Physiol 2022; 600(5): 1189-1208. https://www.ncbi.nlm.nih.gov/pubmed/34555180
- Guillamat-Prats R, Hering D, Derle A, Rami M, Hardtner C, Santovito D, Rinne P, Bindila L, Hristov M, Pagano S, Vuilleumier N, Schmid S, Janjic A, Enard W, Weber C, Maegdefessel L, Faussner A, Hilgendorf I, Steffens S. GPR55 in B cells limits atherosclerosis development and regulates plasma cell maturation. Nat Cardiovasc Res 2022; 1: 1056-1071. https://www.ncbi.nlm.nih.gov/pubmed/36523570
- Habenicht LKL, Wang Z, Zhang X, Li Y, Mogler C, Huspenina JS, Schmid RM, Weber C, Mohanta SK, Ma Z, Yin C. The C1q-ApoE complex: A new hallmark pathology of viral hepatitis and nonalcoholic fatty liver disease. Frontiers in Immunology 2022; 13: 970938. https://www.ncbi.nlm.nih.gov/pubmed/36304458
- Haghikia A, Zimmermann F, Schumann P, Jasina A, Roessler J, Schmidt D, Heinze P, Kaisler J, Nageswaran V, Aigner A, Ceglarek U, Cineus R, Hegazy AN, van der Vorst EPC, Doring Y, Strauch CM, Nemet I, Tremaroli V, Dwibedi C, Krankel N, Leistner DM, Heimesaat MM, Bereswill S, Rauch G, Seeland U, Soehnlein O, Muller DN, Gold R, Backhed F, Hazen SL, Haghikia A, Landmesser U. Propionate attenuates atherosclerosis by immune-dependent regulation of intestinal cholesterol metabolism. Eur Heart J 2022; 43(6): 518-533. https://www.ncbi.nlm.nih.gov/pubmed/34597388
- Hettwer J, Hinterdobler J, Miritsch B, Deutsch MA, Li X, Mauersberger C, Moggio A, Braster Q, Gram H, Robertson AAB, Cooper MA, Gross O, Krane M, Weber C, Koenig W, Soehnlein O, Adamstein NH, Ridker P, Schunkert H, Libby P, Kessler T, Sager HB. Interleukin-1beta suppression dampens inflammatory leucocyte production and uptake in atherosclerosis. Cardiovasc Res 2022; 118(13): 2778-2791. https://www.ncbi.nlm.nih.gov/pubmed/34718444
- Heuschkel MA, Babler A, Heyn J, van der Vorst EPC, Steenman M, Gesper M, Kappel BA, Magne D, Goueffic Y, Kramann R, Jahnen-Dechent W, Marx N, Quillard T, Goettsch C. Distinct role of mitochondrial function and protein kinase C in intimal and medial calcification in vitro. Front Cardiovasc Med 2022; 9: 959457. https://www.ncbi.nlm.nih.gov/pubmed/36204585
- Immler R, Nadolni W, Bertsch A, Morikis V, Rohwedder I, Masgrau-Alsina S, Schroll T, Yevtushenko A, Soehnlein O, Moser M, Gudermann T, Barnea ER, Rehberg M, Simon SI, Zierler S, Pruenster M, Sperandio M. The voltage-gated potassium channel KV1.3 regulates neutrophil recruitment during inflammation. Cardiovasc Res 2022; 118(5): 1289-1302. https://www.ncbi.nlm.nih.gov/pubmed/33881519
- Kahles F, Rau M, Reugels M, Foldenauer AC, Mertens RW, Arrivas MC, Schroder J, Idel P, Moellmann J, van der Vorst EPC, Marx N, Lehrke M. The gut hormone glucose-dependent insulinotropic polypeptide is downregulated in response to myocardial injury. Cardiovasc Diabetol 2022; 21(1): 18. https://www.ncbi.nlm.nih.gov/pubmed/35123462
- Kane J, Jansen M, Hendrix S, Bosmans LA, Beckers L, Tiel CV, Gijbels M, Zelcer N, Vries CJ, von Hundelshausen P, Vervloet M, Eringa E, Horrevoets AJ, Royen NV, Lutgens E. Anti-Galectin-2 Antibody Treatment Reduces Atherosclerotic Plaque Size and Alters Macrophage Polarity. Thromb Haemost 2022; 122(6): 1047-1057. https://www.ncbi.nlm.nih.gov/pubmed/34852377
- Karshovska E, Mohibullah R, Zhu M, Zahedi F, Thomas D, Magkrioti C, Geissler C, Megens RTA, Bianchini M, Nazari-Jahantigh M, Ferreiros N, Aidinis V, Schober A. Endothelial ENPP2 (Ectonucleotide Pyrophosphatase/Phosphodiesterase 2) Increases Atherosclerosis in Female and Male Mice. Arterioscler Thromb Vasc Biol 2022; 42(8): 1023-1036. https://www.ncbi.nlm.nih.gov/pubmed/35708027
- Kichi ZA, Natarelli L, Sadeghian S, Boroumand MA, Behmanesh M, Weber C. Orphan GPR26 Counteracts Early Phases of Hyperglycemia-Mediated Monocyte Activation and Is Suppressed in Diabetic Patients. Biomedicines 2022; 10(7). https://www.ncbi.nlm.nih.gov/pubmed/35885041
- Kichi ZA, Sabouri SG. Multiple Airy beam generation by a digital micro mirror device. Opt Express 2022; 30(13): 23025-23034. https://www.ncbi.nlm.nih.gov/pubmed/36224991
- Kichi ZA, Soltani M, Rezaei M, Shirvani-Farsani Z, Rojhannezhad M. The Emerging Role of EMT-related lncRNAs in Therapy Resistance and their Applications as Biomarkers. Curr Med Chem 2022; 29(26): 4574-4601. https://www.ncbi.nlm.nih.gov/pubmed/35352644
- Kleist CJ, Choe CU, Atzler D, Schonhoff M, Boger R, Schwedhelm E, Wicha SG. Population kinetics of homoarginine and optimized supplementation for cardiovascular risk reduction. Amino Acids 2022; 54(6): 889-896. https://www.ncbi.nlm.nih.gov/pubmed/35618975
- Koenen RR, Weber C. Jam-A Unleashed Incites Thromboinflammatory Coronary Artery Disease. JACC Basic Transl Sci 2022; 7(5): 462-464. https://www.ncbi.nlm.nih.gov/pubmed/35663635
- Kotschi S, Jung A, Willemsen N, Ofoghi A, Proneth B, Conrad M, Bartelt A. NFE2L1-mediated proteasome function protects from ferroptosis. Mol Metab 2022; 57: 101436. https://www.ncbi.nlm.nih.gov/pubmed/34999280
- Kou JJ, Shi JZ, He YY, Hao JJ, Zhang HY, Luo DM, Song JK, Yan Y, Xie XM, Du GH, Pang XB. Luteolin alleviates cognitive impairment in Alzheimer's disease mouse model via inhibiting endoplasmic reticulum stress-dependent neuroinflammation. Acta Pharmacol Sin 2022; 43(4): 840-849. https://www.ncbi.nlm.nih.gov/pubmed/34267346
- Leberzammer J, Agten SM, Blanchet X, Duan R, Ippel H, Megens RTA, Schulz C, Aslani M, Duchene J, Doring Y, Jooss NJ, Zhang P, Brandl R, Stark K, Siess W, Jurk K, Heemskerk JWM, Hackeng TM, Mayo KH, Weber C, von Hundelshausen P. Targeting platelet-derived CXCL12 impedes arterial thrombosis. Blood 2022; 139(17): 2691-2705. https://www.ncbi.nlm.nih.gov/pubmed/35313337
- Lecour S, Du Pre BC, Botker HE, Brundel B, Daiber A, Davidson SM, Ferdinandy P, Girao H, Gollmann-Tepekoylu C, Gyongyosi M, Hausenloy DJ, Madonna R, Marber M, Perrino C, Pesce M, Schulz R, Sluijter JPG, Steffens S, Van Linthout S, Young ME, Van Laake LW. Circadian rhythms in ischaemic heart disease: key aspects for preclinical and translational research: position paper of the ESC working group on cellular biology of the heart. Cardiovasc Res 2022; 118(12): 2566-2581. https://www.ncbi.nlm.nih.gov/pubmed/34505881
- Lesage A, Marceau F, Gibson C, Loenders B, Katzer W, Ambrosi HD, Saupe J, Faussner A, Pardali E, Knolle J. In vitro pharmacological profile of PHA-022121, a small molecule bradykinin B(2) receptor antagonist in clinical development. Int Immunopharmacol 2022; 105: 108523. https://www.ncbi.nlm.nih.gov/pubmed/35086057
- Lip GYH, Rigby A, Weber C. A Rollercoaster Plunge into 2022. Thrombosis and Haemostasis 2022; 122(01): 001-004. https://www.ncbi.nlm.nih.gov/pubmed/35038759
- Liu Y, Shi JZ, Jiang R, Liu SF, He YY, van der Vorst EPC, Weber C, Doring Y, Yan Y. Regulatory T Cell-Related Gene Indicators in Pulmonary Hypertension. Front Pharmacol 2022; 13: 908783. https://www.ncbi.nlm.nih.gov/pubmed/35712711
- Matta L, de Faria CC, De Oliveira DF, Andrade IS, Lima-Junior NC, Gregorio BM, Takiya CM, Ferreira ACF, Nascimento JHM, de Carvalho DP, Bartelt A, Maciel L, Fortunato RS. Exercise Improves Redox Homeostasis and Mitochondrial Function in White Adipose Tissue. Antioxidants (Basel) 2022; 11(9). https://www.ncbi.nlm.nih.gov/pubmed/36139762
- Mauersberger C, Sager HB, Wobst J, Dang TA, Lambrecht L, Koplev S, Stroth M, Bettaga N, Schlossmann J, Wunder F, Friebe A, Björkegren JLM, Dietz L, Maas SL, van der Vorst EPC, Sandner P, Soehnlein O, Schunkert H, Kessler T. Loss of soluble guanylyl cyclase in platelets contributes to atherosclerotic plaque formation and vascular inflammation. Nature Cardiovascular Research 2022; 1(12): 1174-1186. https://doi.org/10.1038/s44161-022-00175-w
- Mohanta SK, Peng L, Li Y, Lu S, Sun T, Carnevale L, Perrotta M, Ma Z, Forstera B, Stanic K, Zhang C, Zhang X, Szczepaniak P, Bianchini M, Saeed BR, Carnevale R, Hu D, Nosalski R, Pallante F, Beer M, Santovito D, Erturk A, Mettenleiter TC, Klupp BG, Megens RTA, Steffens S, Pelisek J, Eckstein HH, Kleemann R, Habenicht L, Mallat Z, Michel JB, Bernhagen J, Dichgans M, D'Agostino G, Guzik TJ, Olofsson PS, Yin C, Weber C, Lembo G, Carnevale D, Habenicht AJR. Neuroimmune cardiovascular interfaces control atherosclerosis. Nature 2022; 605(7908): 152-159. https://www.ncbi.nlm.nih.gov/pubmed/35477759
- Mohanta SK, Weber C, Yin C, Habenicht AJR. The dawn has come for new therapeutics to treat atherosclerosis: Targeting neuroimmune cardiovascular interfaces in artery brain circuits. Clin Transl Med 2022; 12(9): e1040. https://www.ncbi.nlm.nih.gov/pubmed/36052959
- Nagy M, van der Meijden PEJ, Glunz J, Schurgers L, Lutgens E, Ten Cate H, Heitmeier S, Spronk HMH. Integrating Mechanisms in Thrombotic Peripheral Arterial Disease. Pharmaceuticals (Basel) 2022; 15(11). https://www.ncbi.nlm.nih.gov/pubmed/36422558
- Nardi V, Franchi F, Prasad M, Fatica EM, Alexander MP, Bois MC, Lam J, Singh RJ, Meyer FB, Lanzino G, Xiong Y, Lutgens E, Lerman LO, Lerman A. Uric Acid Expression in Carotid Atherosclerotic Plaque and Serum Uric Acid Are Associated With Cerebrovascular Events. Hypertension 2022; 79(8): 1814-1823. https://www.ncbi.nlm.nih.gov/pubmed/35656807
- Natarelli L, Weber C. A Non-Canonical Link between Non-Coding RNAs and Cardiovascular Diseases. Biomedicines 2022; 10(2). https://www.ncbi.nlm.nih.gov/pubmed/35203652
- Nitz K, Lacy M, Bianchini M, Wichapong K, Kucukgoze IA, Bonfiglio CA, Migheli R, Wu Y, Burger C, Li Y, Forne I, Ammar C, Janjic A, Mohanta S, Duchene J, Heemskerk JWM, Megens RTA, Schwedhelm E, Huveneers S, Lygate CA, Santovito D, Zimmer R, Imhof A, Weber C, Lutgens E, Atzler D. The Amino Acid Homoarginine Inhibits Atherogenesis by Modulating T-Cell Function. Circ Res 2022; 131(8): 701-712. https://www.ncbi.nlm.nih.gov/pubmed/36102188
- Ouweneel AB, Reiche ME, Snip OSC, Wever R, van der Wel EJ, Schaftenaar FH, Kauerova S, Lutgens E, Van Eck M, Hoekstra M. Apolipoprotein A1 deficiency in mice primes bone marrow stem cells for T cell lymphopoiesis. J Cell Sci 2022; 135(5). https://www.ncbi.nlm.nih.gov/pubmed/34698355
- Pattarabanjird T, Marshall M, Upadhye A, Srikakulapu P, Garmey JC, Haider A, Taylor AM, Lutgens E, McNamara CA. B-1b Cells Possess Unique bHLH-Driven P62-Dependent Self-Renewal and Atheroprotection. Circ Res 2022; 130(7): 981-993. https://www.ncbi.nlm.nih.gov/pubmed/35209718
- Peters LJF, Baaten C, Maas SL, Lu C, Nagy M, Jooss NJ, Bidzhekov K, Santovito D, Moreno-Andres D, Jankowski J, Biessen EAL, Doring Y, Heemskerk JWM, Weber C, Kuijpers MJE, van der Vorst EPC. MicroRNA-26b Attenuates Platelet Adhesion and Aggregation in Mice. Biomedicines 2022; 10(5). https://www.ncbi.nlm.nih.gov/pubmed/35625720
- Poelman H, Ippel H, Gurkan B, Boelens R, Vriend G, Veer CV, Lutgens E, Nicolaes GAF. Structural anomalies in a published NMR-derived structure of IRAK-M. J Mol Graph Model 2022; 111: 108061. https://www.ncbi.nlm.nih.gov/pubmed/34837785
- Poels K, Schreurs M, Jansen M, Vugts DJ, Seijkens TTP, van Dongen G, Lutgens E, Beaino W. Immuno-PET Imaging of Atherosclerotic Plaques with [(89)Zr]Zr-Anti-CD40 mAb-Proof of Concept. Biology (Basel) 2022; 11(3). https://www.ncbi.nlm.nih.gov/pubmed/35336782
- Rot A, Gutjahr JC, Biswas A, Aslani M, Hub E, Thiriot A, von Andrian UH, Megens RTA, Weber C, Duchene J. Murine bone marrow macrophages and human monocytes do not express atypical chemokine receptor 1. Cell Stem Cell 2022; 29(7): 1013-1015. https://www.ncbi.nlm.nih.gov/pubmed/35803222
- Santovito D, Weber C. Non-canonical features of microRNAs: paradigms emerging from cardiovascular disease. Nat Rev Cardiol 2022; 19(9): 620-638. https://www.ncbi.nlm.nih.gov/pubmed/35304600
- Sauter M, Sauter RJ, Nording H, Lin C, Olbrich M, Autenrieth S, Gleissner C, Thunemann M, Otero N, Lutgens E, Aherrahrou Z, Wolf D, Zender L, Meuth S, Feil R, Langer HF. Apolipoprotein E derived from CD11c(+) cells ameliorates atherosclerosis. iScience 2022; 25(1): 103677. https://www.ncbi.nlm.nih.gov/pubmed/35036868
- Schober A, Maleki SS, Nazari-Jahantigh M. Regulatory Non-coding RNAs in Atherosclerosis. Handb Exp Pharmacol 2022; 270: 463-492. https://www.ncbi.nlm.nih.gov/pubmed/33454857
- Shah M, He Z, Rauf A, Beikoghli Kalkhoran S, Heiestad CM, Stenslokken KO, Parish CR, Soehnlein O, Arjun S, Davidson SM, Yellon D. Extracellular histones are a target in myocardial ischaemia-reperfusion injury. Cardiovasc Res 2022; 118(4): 1115-1125. https://www.ncbi.nlm.nih.gov/pubmed/33878183
- Soppert J, Frisch J, Wirth J, Hemmers C, Boor P, Kramann R, Vondenhoff S, Moellmann J, Lehrke M, Hohl M, van der Vorst EPC, Werner C, Speer T, Maack C, Marx N, Jankowski J, Roma LP, Noels H. A systematic review and meta-analysis of murine models of uremic cardiomyopathy. Kidney Int 2022; 101(2): 256-273. https://www.ncbi.nlm.nih.gov/pubmed/34774555
- Steffens S, Nahrendorf M, Madonna R. Immune cells in cardiac homeostasis and disease: emerging insights from novel technologies. Eur Heart J 2022; 43(16): 1533-1541. https://www.ncbi.nlm.nih.gov/pubmed/34897403
- Sun T, Li Y, Forstera B, Stanic K, Lu S, Steffens S, Yin C, Erturk A, Megens RTA, Weber C, Habenicht A, Mohanta SK. Tissue Clearing Approaches in Atherosclerosis. Methods Mol Biol 2022; 2419: 747-763. https://www.ncbi.nlm.nih.gov/pubmed/35237999
- Tas K, Volta BD, Lindner C, El Bounkari O, Hille K, Tian Y, Puig-Bosch X, Ballmann M, Hornung S, Ortner M, Prem S, Meier L, Rammes G, Haslbeck M, Weber C, Megens RTA, Bernhagen J, Kapurniotu A. Designed peptides as nanomolar cross-amyloid inhibitors acting via supramolecular nanofiber co-assembly. Nat Commun 2022; 13(1): 5004. https://www.ncbi.nlm.nih.gov/pubmed/36008417
- Tullemans BME, Fernandez DI, Veninga A, Baaten C, Peters LJF, Aarts MJB, Eble JA, Campello E, Spiezia L, Simioni P, van der Vorst EPC, van der Meijden PEJ, Heemskerk JWM, Kuijpers MJE. Tyrosine Kinase Inhibitor Sunitinib Delays Platelet-Induced Coagulation: Additive Effects of Aspirin. Thromb Haemost 2022; 122(1): 92-104. https://www.ncbi.nlm.nih.gov/pubmed/34130349
- van der Velden J, Asselbergs FW, Bakkers J, Batkai S, Bertrand L, Bezzina CR, Bot I, Brundel B, Carrier L, Chamuleau S, Ciccarelli M, Dawson D, Davidson SM, Dendorfer A, Duncker DJ, Eschenhagen T, Fabritz L, Falcao-Pires I, Ferdinandy P, Giacca M, Girao H, Gollmann-Tepekoylu C, Gyongyosi M, Guzik TJ, Hamdani N, Heymans S, Hilfiker A, Hilfiker-Kleiner D, Hoekstra AG, Hulot JS, Kuster DWD, van Laake LW, Lecour S, Leiner T, Linke WA, Lumens J, Lutgens E, Madonna R, Maegdefessel L, Mayr M, van der Meer P, Passier R, Perbellini F, Perrino C, Pesce M, Priori S, Remme CA, Rosenhahn B, Schotten U, Schulz R, Sipido KR, Sluijter JPG, van Steenbeek F, Steffens S, Terracciano CM, Tocchetti CG, Vlasman P, Yeung KK, Zacchigna S, Zwaagman D, Thum T. Animal models and animal-free innovations for cardiovascular research: current status and routes to be explored. Consensus document of the ESC Working Group on Myocardial Function and the ESC Working Group on Cellular Biology of the Heart. Cardiovasc Res 2022; 118(15): 3016-3051. https://www.ncbi.nlm.nih.gov/pubmed/34999816
- Van der Vorst EPC, Biessen EAL. Unwrapped and uNCORked: PPAR-gamma repression in atherosclerosis. Eur Heart J 2022; 43(7): e32-e34. https://www.ncbi.nlm.nih.gov/pubmed/31754688
- van der Vorst EPC, Doring Y. How slimming regulatory T cells limit atherosclerosis: Mechanistic insights into T cell lipid metabolism. Atherosclerosis 2022; 362: 23-25. https://www.ncbi.nlm.nih.gov/pubmed/36400604
- van der Vorst EPC, Lecour S. Finding the culprit for the failure of the immune clock as time goes by. Cardiovasc Res 2022; 118(13): e88-e90. https://www.ncbi.nlm.nih.gov/pubmed/36065125
- Vos WG, Lutgens E, Seijkens TTP. Statins and immune checkpoint inhibitors: a strategy to improve the efficacy of immunotherapy for cancer? Journal for ImmunoTherapy of Cancer 2022; 10(9).
- Wang S, Yan Y, Xu WJ, Gong SG, Zhong XJ, An QY, Zhao YL, Liu JM, Wang L, Yuan P, Jiang R. The Role of Glutamine and Glutaminase in Pulmonary Hypertension. Front Cardiovasc Med 2022; 9: 838657. https://www.ncbi.nlm.nih.gov/pubmed/35310969
- Wang Z, Zhang X, Zhang C, Li Y, Lu S, Mohanta S, Weber C, Habenicht A, Yin C. Combined Single-Cell RNA and Single-Cell alpha/beta T Cell Receptor Sequencing of the Arterial Wall in Atherosclerosis. Methods Mol Biol 2022; 2419: 727-746. https://www.ncbi.nlm.nih.gov/pubmed/35237998
- Weber C, Rigby A, Lip GYH. Thrombosis and Haemostasis 2021 Editors' Choice Papers. Thrombosis and Haemostasis 2022; 122(01): 163-170. https://www.ncbi.nlm.nih.gov/pubmed/35038760
- Weber E, Richter E, Holze R. o-Toluidine in electrochemistry – an overview. Journal of Solid State Electrochemistry 2022; 26(4): 1097-1114. <Go to ISI>://WOS:000763897400001
- Willemsen N, Arigoni I, Studencka-Turski M, Kruger E, Bartelt A. Proteasome dysfunction disrupts adipogenesis and induces inflammation via ATF3. Mol Metab 2022; 62: 101518. https://www.ncbi.nlm.nih.gov/pubmed/35636710
- Willemsen N, Kotschi S, Bartelt A. Fire up the pyre: inosine thermogenic signaling for obesity therapy. Signal Transduct Target Ther 2022; 7(1): 375. https://www.ncbi.nlm.nih.gov/pubmed/36357366
- Wollenhaupt J, Frisch J, Harlacher E, Wong DWL, Jin H, Schulte C, Vondenhoff S, Moellmann J, Klinkhammer BM, Zhang L, Baleanu-Curaj A, Liehn EA, Speer T, Kazakov A, Werner C, van der Vorst EPC, Selejan SR, Hohl M, Bohm M, Kramann R, Biessen EAL, Lehrke M, Marx N, Jankowski J, Maack C, Boor P, Prates Roma L, Noels H. Pro-oxidative priming but maintained cardiac function in a broad spectrum of murine models of chronic kidney disease. Redox Biol 2022; 56: 102459. https://www.ncbi.nlm.nih.gov/pubmed/36099852
- Worthmann A, Bartelt A. MALDI MSI for a fresh view on atherosclerotic plaque lipids. Pflugers Arch 2022; 474(2): 185-186. https://www.ncbi.nlm.nih.gov/pubmed/34928417
- Zhang X, Wang Z, Zhang C, Li Y, Lu S, Steffens S, Mohanta S, Weber C, Habenicht A, Yin C. Laser Capture Microdissection-Based mRNA Expression Microarrays and Single-Cell RNA Sequencing in Atherosclerosis Research. Methods Mol Biol 2022; 2419: 715-726. https://www.ncbi.nlm.nih.gov/pubmed/35237997
- Zhang Y, Garcia-Ibanez L, Ulbricht C, Lok LSC, Pike JA, Mueller-Winkler J, Dennison TW, Ferdinand JR, Burnett CJM, Yam-Puc JC, Zhang L, Alfaro RM, Takahama Y, Ohigashi I, Brown G, Kurosaki T, Tybulewicz VLJ, Rot A, Hauser AE, Clatworthy MR, Toellner K-M. Recycling of memory B cells between germinal center and lymph node subcapsular sinus supports affinity maturation to antigenic drift. Nature Communications 2022; 13(1): 2460. https://www.ncbi.nlm.nih.gov/pubmed/35513371
- Abdel Rahman F, d'Almeida S, Zhang T, Asadi M, Bozoglu T, Bongiovanni D, von Scheidt M, Dietzel S, Schwedhelm E, Hinkel R, Laugwitz KL, Kupatt C, Ziegler T. Sphingosine-1-Phosphate Attenuates Lipopolysaccharide-Induced Pericyte Loss via Activation of Rho-A and MRTF-A. Thromb Haemost 2021; 121(3): 341-350. https://www.ncbi.nlm.nih.gov/pubmed/33011963
- Alexander Y, Osto E, Schmidt-Trucksass A, Shechter M, Trifunovic D, Duncker DJ, Aboyans V, Back M, Badimon L, Cosentino F, De Carlo M, Dorobantu M, Harrison DG, Guzik TJ, Hoefer I, Morris PD, Norata GD, Suades R, Taddei S, Vilahur G, Waltenberger J, Weber C, Wilkinson F, Bochaton-Piallat ML, Evans PC. Endothelial function in cardiovascular medicine: a consensus paper of the European Society of Cardiology Working Groups on Atherosclerosis and Vascular Biology, Aorta and Peripheral Vascular Diseases, Coronary Pathophysiology and Microcirculation, and Thrombosis. Cardiovasc Res 2021; 117(1): 29-42. https://www.ncbi.nlm.nih.gov/pubmed/32282914
- Barkaway A, Rolas L, Joulia R, Bodkin J, Lenn T, Owen-Woods C, Reglero-Real N, Stein M, Vazquez-Martinez L, Girbl T, Poston RN, Golding M, Saleeb RS, Thiriot A, von Andrian UH, Duchene J, Voisin MB, Bishop CL, Voehringer D, Roers A, Rot A, Lammermann T, Nourshargh S. Age-related changes in the local milieu of inflamed tissues cause aberrant neutrophil trafficking and subsequent remote organ damage. Immunity 2021; 54(7): 1494-1510 e1497. https://www.ncbi.nlm.nih.gov/pubmed/34033752
- Bernlochner I, Klug M, Larasati D, Von Scheidt M, Santovito D, Hristov M, Weber C, Laugwitz KL, Bongiovanni D. Sorting and magnetic-based isolation of reticulated platelets from peripheral blood. Platelets 2021; 32(1): 113-119. https://www.ncbi.nlm.nih.gov/pubmed/32046562
- Bosmans LA, Bosch L, Kusters PJH, Lutgens E, Seijkens TTP. The CD40-CD40L Dyad as Immunotherapeutic Target in Cardiovascular Disease. J Cardiovasc Transl Res 2021; 14(1): 13-22. https://www.ncbi.nlm.nih.gov/pubmed/32222950
- Bosmans LA, Shami A, Atzler D, Weber C, Goncalves I, Lutgens E. Glucocorticoid induced TNF receptor family-related protein (GITR) - A novel driver of atherosclerosis. Vascul Pharmacol 2021; 139: 106884. https://www.ncbi.nlm.nih.gov/pubmed/34102305
- Chirivi RGS, van Rosmalen JWG, van der Linden M, Euler M, Schmets G, Bogatkevich G, Kambas K, Hahn J, Braster Q, Soehnlein O, Hoffmann MH, Es H, Raats JMH. Therapeutic ACPA inhibits NET formation: a potential therapy for neutrophil-mediated inflammatory diseases. Cell Mol Immunol 2021; 18(6): 1528-1544. https://www.ncbi.nlm.nih.gov/pubmed/32203195
- Chondronikola M, Bartelt A, Vidal-Puig A, Virtanen KA. Editorial: Brown Adipose Tissue: From Heat Production in Rodents to Metabolic Health in Humans. Front Endocrinol (Lausanne) 2021; 12: 739065. https://www.ncbi.nlm.nih.gov/pubmed/34381425
- Datta-Chaudhuri T, Zanos T, Chang EH, Olofsson PS, Bickel S, Bouton C, Grande D, Rieth L, Aranow C, Bloom O, Mehta AD, Civillico G, Stevens MM, Glowacki E, Bettinger C, Schuettler M, Puleo C, Rennaker R, Mohanta S, Carnevale D, Conde SV, Bonaz B, Chernoff D, Kapa S, Berggren M, Ludwig K, Zanos S, Miller L, Weber D, Yoshor D, Steinman L, Chavan SS, Pavlov VA, Al-Abed Y, Tracey KJ. The Fourth Bioelectronic Medicine Summit "Technology Targeting Molecular Mechanisms": current progress, challenges, and charting the future. Bioelectron Med 2021; 7(1): 7. https://www.ncbi.nlm.nih.gov/pubmed/34024277
- Davidson SM, Padro T, Bollini S, Vilahur G, Duncker DJ, Evans PC, Guzik T, Hoefer IE, Waltenberger J, Wojta J, Weber C. Progress in cardiac research: from rebooting cardiac regeneration to a complete cell atlas of the heart. Cardiovasc Res 2021; 117(10): 2161-2174. https://www.ncbi.nlm.nih.gov/pubmed/34114614
- Dickhout A, Kaczor DM, Heinzmann ACA, Brouns SLN, Heemskerk JWM, van Zandvoort M, Koenen RR. Rapid Internalization and Nuclear Translocation of CCL5 and CXCL4 in Endothelial Cells. Int J Mol Sci 2021; 22(14). https://www.ncbi.nlm.nih.gov/pubmed/34298951
- Dickhout A, Tullemans BME, Heemskerk JWM, Thijssen V, Kuijpers MJE, Koenen RR. Galectin-1 and platelet factor 4 (CXCL4) induce complementary platelet responses in vitro. PLoS One 2021; 16(1): e0244736. https://www.ncbi.nlm.nih.gov/pubmed/33411760
- Duan R, Goldmann L, Brandl R, Spannagl M, Weber C, Siess W, von Hundelshausen P. Effects of the Btk-Inhibitors Remibrutinib (LOU064) and Rilzabrutinib (PRN1008) With Varying Btk Selectivity Over Tec on Platelet Aggregation and in vitro Bleeding Time. Front Cardiovasc Med 2021; 8: 749022. https://www.ncbi.nlm.nih.gov/pubmed/34631841
- Duan R, Goldmann L, Li Y, Weber C, Siess W, von Hundelshausen P. Spontaneous Platelet Aggregation in Blood Is Mediated by FcgammaRIIA Stimulation of Bruton's Tyrosine Kinase. Int J Mol Sci 2021; 23(1). https://www.ncbi.nlm.nih.gov/pubmed/35008508
- Egea V, Kessenbrock K, Lawson D, Bartelt A, Weber C, Ries C. Let-7f miRNA regulates SDF-1alpha- and hypoxia-promoted migration of mesenchymal stem cells and attenuates mammary tumor growth upon exosomal release. Cell Death Dis 2021; 12(6): 516. https://www.ncbi.nlm.nih.gov/pubmed/34016957
- Evans P, Wojta J, Hoefer IE, Waltenberger J, Guzik T, Badimon L, Weber C. The year in basic vascular biology research: from mechanoreceptors and neutrophil extracellular traps to smartphone data and omics. Cardiovasc Res 2021; 117(8): 1814-1822. https://www.ncbi.nlm.nih.gov/pubmed/33744925
- Fasolo F, Jin H, Winski G, Chernogubova E, Pauli J, Winter H, Li DY, Glukha N, Bauer S, Metschl S, Wu Z, Koschinsky ML, Reilly M, Pelisek J, Kempf W, Eckstein HH, Soehnlein O, Matic L, Hedin U, Backlund A, Bergmark C, Paloschi V, Maegdefessel L. Long Noncoding RNA MIAT Controls Advanced Atherosclerotic Lesion Formation and Plaque Destabilization. Circulation 2021; 144(19): 1567-1583. https://www.ncbi.nlm.nih.gov/pubmed/34647815
- Fidler TP, Xue C, Yalcinkaya M, Hardaway B, Abramowicz S, Xiao T, Liu W, Thomas DG, Hajebrahimi MA, Pircher J, Silvestre-Roig C, Kotini AG, Luchsinger LL, Wei Y, Westerterp M, Snoeck HW, Papapetrou EP, Schulz C, Massberg S, Soehnlein O, Ebert B, Levine RL, Reilly MP, Libby P, Wang N, Tall AR. The AIM2 inflammasome exacerbates atherosclerosis in clonal haematopoiesis. Nature 2021; 592(7853): 296-301. https://www.ncbi.nlm.nih.gov/pubmed/33731931
- Gencer S, Doring Y, Jansen Y, Bayasgalan S, Schengel O, Muller M, Peters LJF, Weber C, van der Vorst EPC. Adipocyte-Specific ACKR3 Regulates Lipid Levels in Adipose Tissue. Biomedicines 2021; 9(4): 11. https://www.ncbi.nlm.nih.gov/pubmed/33917642
- Gencer S, Evans BR, van der Vorst EPC, Doring Y, Weber C. Inflammatory Chemokines in Atherosclerosis. Cells 2021; 10(2). https://www.ncbi.nlm.nih.gov/pubmed/33503867
- Georgakis MK, van der Laan SW, Asare Y, Mekke JM, Haitjema S, Schoneveld AH, de Jager SCA, Nurmohamed NS, Kroon J, Stroes ESG, de Kleijn DPV, de Borst GJ, Maegdefessel L, Soehnlein O, Pasterkamp G, Dichgans M. Monocyte-Chemoattractant Protein-1 Levels in Human Atherosclerotic Lesions Associate With Plaque Vulnerability. Arterioscler Thromb Vasc Biol 2021; 41(6): 2038-2048. https://www.ncbi.nlm.nih.gov/pubmed/33827260
- Ghiboub M, Elfiky AMI, de Winther MPJ, Harker NR, Tough DF, de Jonge WJ. Selective Targeting of Epigenetic Readers and Histone Deacetylases in Autoimmune and Inflammatory Diseases: Recent Advances and Future Perspectives. J Pers Med 2021; 11(5). https://www.ncbi.nlm.nih.gov/pubmed/33922725
- Giroud M, Tsokanos FF, Caratti G, Kotschi S, Khani S, Jouffe C, Vogl ES, Irmler M, Glantschnig C, Gil-Lozano M, Hass D, Khan AA, Garcia MR, Mattijssen F, Maida A, Tews D, Fischer-Posovszky P, Feuchtinger A, Virtanen KA, Beckers J, Wabitsch M, Uhlenhaut H, Bluher M, Tuckermann J, Scheideler M, Bartelt A, Herzig S. HAND2 is a novel obesity-linked adipogenic transcription factor regulated by glucocorticoid signalling. Diabetologia 2021; 64(8): 1850-1865. https://www.ncbi.nlm.nih.gov/pubmed/34014371
- Gissler MC, Scherrer P, Anto-Michel N, Pennig J, Hoppe N, Funer L, Hardtner C, Stachon P, Li X, Mitre LS, Marchini T, Madl J, Wadle C, Hilgendorf I, von Zur Muhlen C, Bode C, Weber C, Lutgens E, Wolf D, Gerdes N, Zirlik A, Willecke F. Deficiency of Endothelial CD40 Induces a Stable Plaque Phenotype and Limits Inflammatory Cell Recruitment to Atherosclerotic Lesions in Mice. Thromb Haemost 2021; 121(11): 1530-1540. https://www.ncbi.nlm.nih.gov/pubmed/33618394
- Goncalves RLS, Schlame M, Bartelt A, Brand MD, Hotamisligil GS. Cardiolipin deficiency in Barth syndrome is not associated with increased superoxide/H(2) O(2) production in heart and skeletal muscle mitochondria. FEBS Lett 2021; 595(3): 415-432. https://www.ncbi.nlm.nih.gov/pubmed/33112430
- Gutjahr JC, Crawford KS, Jensen DR, Naik P, Peterson FC, Samson GPB, Legler DF, Duchene J, Veldkamp CT, Rot A, Volkman BF. The dimeric form of CXCL12 binds to atypical chemokine receptor 1. Sci Signal 2021; 14(696). https://www.ncbi.nlm.nih.gov/pubmed/34404752
- Hall IF, Climent M, Viviani Anselmi C, Papa L, Tragante V, Lambroia L, Farina FM, Kleber ME, Marz W, Biguori C, Condorelli G, Elia L. rs41291957 controls miR-143 and miR-145 expression and impacts coronary artery disease risk. EMBO Mol Med 2021; 13(10): e14060. https://www.ncbi.nlm.nih.gov/pubmed/34551209
- He YY, Xie XM, Zhang HD, Ye J, Gencer S, van der Vorst EPC, Doring Y, Weber C, Pang XB, Jing ZC, Yan Y, Han ZY. Identification of Hypoxia Induced Metabolism Associated Genes in Pulmonary Hypertension. Front Pharmacol 2021; 12: 753727. https://www.ncbi.nlm.nih.gov/pubmed/34803695
- Henderson JM, Weber C, Santovito D. Beyond Self-Recycling: Cell-Specific Role of Autophagy in Atherosclerosis. Cells 2021; 10(3). https://www.ncbi.nlm.nih.gov/pubmed/33799835
- Hinkel R, Batkai S, Bahr A, Bozoglu T, Straub S, Borchert T, Viereck J, Howe A, Hornaschewitz N, Oberberger L, Jurisch V, Kozlik-Feldmann R, Freudenthal F, Ziegler T, Weber C, Sperandio M, Engelhardt S, Laugwitz KL, Moretti A, Klymiuk N, Thum T, Kupatt C. AntimiR-132 Attenuates Myocardial Hypertrophy in an Animal Model of Percutaneous Aortic Constriction. J Am Coll Cardiol 2021; 77(23): 2923-2935. https://www.ncbi.nlm.nih.gov/pubmed/34112319
- Hinterdobler J, Schott S, Jin H, Meesmann A, Steinsiek AL, Zimmermann AS, Wobst J, Muller P, Mauersberger C, Vilne B, Baecklund A, Chen CS, Moggio A, Braster Q, Molitor M, Krane M, Kempf WE, Ladwig KH, Hristov M, Hulsmans M, Hilgendorf I, Weber C, Wenzel P, Scheiermann C, Maegdefessel L, Soehnlein O, Libby P, Nahrendorf M, Schunkert H, Kessler T, Sager HB. Acute mental stress drives vascular inflammation and promotes plaque destabilization in mouse atherosclerosis. Eur Heart J 2021; 42(39): 4077-4088. https://www.ncbi.nlm.nih.gov/pubmed/34279021
- Kassiteridi C, Cole JE, Griseri T, Falck-Hansen M, Goddard ME, Seneviratne AN, Green PA, Park I, Shami AG, Pattarabanjird T, Upadhye A, Taylor AM, Handa A, Channon KM, Lutgens E, McNamara CA, Williams RO, Monaco C. CD200 Limits Monopoiesis and Monocyte Recruitment in Atherosclerosis. Circ Res 2021; 129(2): 280-295. https://www.ncbi.nlm.nih.gov/pubmed/33975450
- Kluza E, Beldman TJ, Shami A, Scholl ER, Malinova TS, Grootemaat AE, van der Wel NN, Goncalves I, Huveneers S, Mulder WJM, Lutgens E. Diverse ultrastructural landscape of atherosclerotic endothelium. Atherosclerosis 2021; 339: 35-45. https://www.ncbi.nlm.nih.gov/pubmed/34847419
- Koenen RR. Conformation-Crooking CXCL4 to Unravel Autoimmune Heparin-Induced Thrombocytopenia. Thromb Haemost 2021; 121(3): 258-260. https://www.ncbi.nlm.nih.gov/pubmed/33385179
- Kou J, Wang M, Shi J, Zhang H, Pu X, Song S, Yang C, Yan Y, Doring Y, Xie X, Pang X. Curcumin Reduces Cognitive Deficits by Inhibiting Neuroinflammation through the Endoplasmic Reticulum Stress Pathway in Apolipoprotein E4 Transgenic Mice. ACS Omega 2021; 6(10): 6654-6662. https://www.ncbi.nlm.nih.gov/pubmed/33748578
- Krammer C, Kontos C, Dewor M, Hille K, Dalla Volta B, El Bounkari O, Tas K, Sinitski D, Brandhofer M, Megens RTA, Weber C, Schultz JR, Bernhagen J, Kapurniotu A. A MIF-Derived Cyclopeptide that Inhibits MIF Binding and Atherogenic Signaling via the Chemokine Receptor CXCR2. Chembiochem 2021; 22(6): 1012-1019. https://www.ncbi.nlm.nih.gov/pubmed/33125165
- Lacy M, Burger C, Shami A, Ahmadsei M, Winkels H, Nitz K, van Tiel CM, Seijkens TTP, Kusters PJH, Karshovka E, Prange KHM, Wu Y, Brouns SLN, Unterlugauer S, Kuijpers MJE, Reiche ME, Steffens S, Edsfeldt A, Megens RTA, Heemskerk JWM, Goncalves I, Weber C, Gerdes N, Atzler D, Lutgens E. Cell-specific and divergent roles of the CD40L-CD40 axis in atherosclerotic vascular disease. Nat Commun 2021; 12(1): 3754. https://www.ncbi.nlm.nih.gov/pubmed/34145241
- Lee MW, Luo EW, Silvestre-Roig C, Srinivasan Y, Akabori K, Lemnitzer P, Schmidt NW, Lai GH, Santangelo CD, Soehnlein O, Wong GCL. Apolipoprotein Mimetic Peptide Inhibits Neutrophil-Driven Inflammatory Damage via Membrane Remodeling and Suppression of Cell Lysis. ACS Nano 2021; 15(10): 15930-15939. https://www.ncbi.nlm.nih.gov/pubmed/34586780
- Lemmer IL, Willemsen N, Hilal N, Bartelt A. A guide to understanding endoplasmic reticulum stress in metabolic disorders. Mol Metab 2021; 47: 101169. https://www.ncbi.nlm.nih.gov/pubmed/33484951
- Lesch S, Blumenberg V, Stoiber S, Gottschlich A, Ogonek J, Cadilha BL, Dantes Z, Rataj F, Dorman K, Lutz J, Karches CH, Heise C, Kurzay M, Larimer BM, Grassmann S, Rapp M, Nottebrock A, Kruger S, Tokarew N, Metzger P, Hoerth C, Benmebarek MR, Dhoqina D, Grunmeier R, Seifert M, Oener A, Umut O, Joaquina S, Vimeux L, Tran T, Hank T, Baba T, Huynh D, Megens RTA, Janssen KP, Jastroch M, Lamp D, Ruehland S, Di Pilato M, Pruessmann JN, Thomas M, Marr C, Ormanns S, Reischer A, Hristov M, Tartour E, Donnadieu E, Rothenfusser S, Duewell P, Konig LM, Schnurr M, Subklewe M, Liss AS, Halama N, Reichert M, Mempel TR, Endres S, Kobold S. T cells armed with C-X-C chemokine receptor type 6 enhance adoptive cell therapy for pancreatic tumours. Nat Biomed Eng 2021; 5(11): 1246-1260. https://www.ncbi.nlm.nih.gov/pubmed/34083764
- Lip GYH, Rigby A, Weber C. Looking Back on 2020, Looking Forward to 2021. Thromb Haemost 2021; 121(1): 1-3. https://www.ncbi.nlm.nih.gov/pubmed/33477196
- Lutgens E, Joffre J, van Os B, Ait-Oufella H. Targeting cytokines and immune checkpoints in atherosclerosis with monoclonal antibodies. Atherosclerosis 2021; 335: 98-109. https://www.ncbi.nlm.nih.gov/pubmed/34593238
- Maciuszek M, Ortega-Gomez A, Maas SL, Garrido-Mesa J, Ferraro B, Perretti M, Merritt A, Nicolaes GAF, Soehnlein O, Chapman TM. Design, synthesis, and biological evaluation of novel pyrrolidinone small-molecule Formyl peptide receptor 2 agonists. Eur J Med Chem 2021; 226: 113805. https://www.ncbi.nlm.nih.gov/pubmed/34536667
- Maciuszek M, Ortega-Gomez A, Maas SL, Perretti M, Merritt A, Soehnlein O, Chapman TM. Synthesis and evaluation of novel cyclopentane urea FPR2 agonists and their potential application in the treatment of cardiovascular inflammation. Eur J Med Chem 2021; 214: 113194. https://www.ncbi.nlm.nih.gov/pubmed/33548634
- Marquez AB, van der Vorst EPC, Maas SL. Key Chemokine Pathways in Atherosclerosis and Their Therapeutic Potential. J Clin Med 2021; 10(17). https://www.ncbi.nlm.nih.gov/pubmed/34501271
- Muley C, Bartelt A. Fuse your mitochondria, lose appetite: an anorexic, anti-obesity sphingolipid. EMBO Mol Med 2021; 13(8): e14618. https://www.ncbi.nlm.nih.gov/pubmed/34288516
- Muley C, Kotschi S, Bartelt A. Role of Ubiquilins for Brown Adipocyte Proteostasis and Thermogenesis. Front Endocrinol (Lausanne) 2021; 12: 739021. https://www.ncbi.nlm.nih.gov/pubmed/34650520
- Natarelli L, Parca L, Mazza T, Weber C, Virgili F, Fratantonio D. MicroRNAs and Long Non-Coding RNAs as Potential Candidates to Target Specific Motifs of SARS-CoV-2. Noncoding RNA 2021; 7(1). https://www.ncbi.nlm.nih.gov/pubmed/33670580
- Natarelli L, Virgili F, Weber C. SARS-CoV-2, Cardiovascular Diseases, and Noncoding RNAs: A Connected Triad. Int J Mol Sci 2021; 22(22). https://www.ncbi.nlm.nih.gov/pubmed/34830125
- Nording H, Baron L, Haberthur D, Emschermann F, Mezger M, Sauter M, Sauter R, Patzelt J, Knoepp K, Nording A, Meusel M, Meyer-Saraei R, Hlushchuk R, Sedding D, Borst O, Eitel I, Karsten CM, Feil R, Pichler B, Erdmann J, Verschoor A, Chavakis E, Chavakis T, von Hundelshausen P, Kohl J, Gawaz M, Langer HF. The C5a/C5a receptor 1 axis controls tissue neovascularization through CXCL4 release from platelets. Nat Commun 2021; 12(1): 3352. https://www.ncbi.nlm.nih.gov/pubmed/34099640
- Perrino C, Ferdinandy P, Botker HE, Brundel B, Collins P, Davidson SM, den Ruijter HM, Engel FB, Gerdts E, Girao H, Gyongyosi M, Hausenloy DJ, Lecour S, Madonna R, Marber M, Murphy E, Pesce M, Regitz-Zagrosek V, Sluijter JPG, Steffens S, Gollmann-Tepekoylu C, Van Laake LW, Van Linthout S, Schulz R, Ytrehus K. Improving translational research in sex-specific effects of comorbidities and risk factors in ischaemic heart disease and cardioprotection: position paper and recommendations of the ESC Working Group on Cellular Biology of the Heart. Cardiovasc Res 2021; 117(2): 367-385. https://www.ncbi.nlm.nih.gov/pubmed/32484892
- Pesce M, Agostoni P, Botker HE, Brundel B, Davidson SM, Caterina R, Ferdinandy P, Girao H, Gyongyosi M, Hulot JS, Lecour S, Perrino C, Schulz R, Sluijter JP, Steffens S, Tancevski I, Gollmann-Tepekoylu C, Tschope C, Linthout SV, Madonna R. COVID-19-related cardiac complications from clinical evidences to basic mechanisms: opinion paper of the ESC Working Group on Cellular Biology of the Heart. Cardiovasc Res 2021; 117(10): 2148-2160. https://www.ncbi.nlm.nih.gov/pubmed/34117887
- Peters LJF, Jans A, Bartneck M, van der Vorst EPC. Immunomodulatory Nanomedicine for the Treatment of Atherosclerosis. J Clin Med 2021; 10(14). https://www.ncbi.nlm.nih.gov/pubmed/34300351
- Poels K, Neppelenbroek SIM, Kersten MJ, Antoni ML, Lutgens E, Seijkens TTP. Immune checkpoint inhibitor treatment and atherosclerotic cardiovascular disease: an emerging clinical problem. J Immunother Cancer 2021; 9(6). https://www.ncbi.nlm.nih.gov/pubmed/34168005
- Puhl SL, Hilby M, Kohlhaas M, Keidel LM, Jansen Y, Hristov M, Schindler J, Maack C, Steffens S. Haematopoietic and cardiac GPR55 synchronize post-myocardial infarction remodelling. Sci Rep 2021; 11(1): 14385. https://www.ncbi.nlm.nih.gov/pubmed/34257332
- Reiche ME, Lutgens E. Lose the helpers... get 'remote' regulators! Cardiovasc Res 2021; 117(3): 635-636. https://www.ncbi.nlm.nih.gov/pubmed/32637996
- Reilly NA, Lutgens E, Kuiper J, Heijmans BT, Jukema JW. Effects of fatty acids on T cell function: role in atherosclerosis. Nat Rev Cardiol 2021; 18(12): 824-837. https://www.ncbi.nlm.nih.gov/pubmed/34253911
- Rossaint J, Thomas K, Mersmann S, Skupski J, Margraf A, Tekath T, Jouvene CC, Dalli J, Hidalgo A, Meuth SG, Soehnlein O, Zarbock A. Platelets orchestrate the resolution of pulmonary inflammation in mice by T reg cell repositioning and macrophage education. J Exp Med 2021; 218(7). https://www.ncbi.nlm.nih.gov/pubmed/34014253
- Santovito D, Steffens S. DNA damage and extranuclear DNA sensors: a dangerous duo in atherosclerosis. Eur Heart J 2021; 42(42): 4349-4351. https://www.ncbi.nlm.nih.gov/pubmed/34226940
- Santovito D, Toto L, De Nardis V, Marcantonio P, D'Aloisio R, Mastropasqua A, De Cesare D, Bucci M, Paganelli C, Natarelli L, Weber C, Consoli A, Mastropasqua R, Cipollone F. Plasma microRNA signature associated with retinopathy in patients with type 2 diabetes. Sci Rep 2021; 11(1): 4136. https://www.ncbi.nlm.nih.gov/pubmed/33602976
- Santovito D, Weber C. Not all myocardial infarctions are created equal: The potential of circulating microRNAs to discern coronary artery dissection. EBioMedicine 2021; 67: 103366. https://www.ncbi.nlm.nih.gov/pubmed/33965874
- Schindler L, Zwissler L, Krammer C, Hendgen-Cotta U, Rassaf T, Hampton MB, Dickerhof N, Bernhagen J. Macrophage migration inhibitory factor inhibits neutrophil apoptosis by inducing cytokine release from mononuclear cells. J Leukoc Biol 2021; 110(5): 893-905. https://www.ncbi.nlm.nih.gov/pubmed/33565160
- Schlein C, Fischer AW, Sass F, Worthmann A, Todter K, Jaeckstein MY, Behrens J, Lynes MD, Kiebish MA, Narain NR, Bussberg V, Darkwah A, Jespersen NZ, Nielsen S, Scheele C, Schweizer M, Braren I, Bartelt A, Tseng YH, Heeren J, Scheja L. Endogenous Fatty Acid Synthesis Drives Brown Adipose Tissue Involution. Cell Rep 2021; 34(2): 108624. https://www.ncbi.nlm.nih.gov/pubmed/33440156
- Schmohl J, Moebius S, Guenther T, Pepeldjyika E, Seidel CL, Sutanto W, Schuster F, Kraemer D, Salih H, Hartmann A, Tischer J, Ries C, Schmetzer H. Expression of Surface-associated 82 kDa proMMP-9 in Lymphatic Leukemia Blast Cells Differentially Correlates With Prognosis. Anticancer Res 2021; 41(8): 3891-3898. https://www.ncbi.nlm.nih.gov/pubmed/34281851
- Schober A, Blay RM, Saboor Maleki S, Zahedi F, Winklmaier AE, Kakar MY, Baatsch IM, Zhu M, Geissler C, Fusco AE, Eberlein A, Li N, Megens RTA, Banafsche R, Kumbrink J, Weber C, Nazari-Jahantigh M. MicroRNA-21 Controls Circadian Regulation of Apoptosis in Atherosclerotic Lesions. Circulation 2021; 144(13): 1059-1073. https://www.ncbi.nlm.nih.gov/pubmed/34233454
- Schoeps B, Eckfeld C, Prokopchuk O, Bottcher J, Haussler D, Steiger K, Demir IE, Knolle P, Soehnlein O, Jenne DE, Hermann CD, Kruger A. TIMP1 Triggers Neutrophil Extracellular Trap Formation in Pancreatic Cancer. Cancer Res 2021; 81(13): 3568-3579. https://www.ncbi.nlm.nih.gov/pubmed/33941611
- Schumacher D, Curaj A, Simsekyilmaz S, Schober A, Liehn EA, Mause SF. miR155 Deficiency Reduces Myofibroblast Density but Fails to Improve Cardiac Function after Myocardial Infarction in Dyslipidemic Mouse Model. Int J Mol Sci 2021; 22(11). https://www.ncbi.nlm.nih.gov/pubmed/34067440
- Schumacher D, Liehn EA, Singh A, Curaj A, Wijnands E, Lira SA, Tacke F, Jankowski J, Biessen EAL, van der Vorst EPC. CCR6 Deficiency Increases Infarct Size after Murine Acute Myocardial Infarction. Biomedicines 2021; 9(11). https://www.ncbi.nlm.nih.gov/pubmed/34829761
- Schumski A, Ortega-Gomez A, Wichapong K, Winter C, Lemnitzer P, Viola JR, Pinilla-Vera M, Folco E, Solis-Mezarino V, Volker-Albert M, Maas SL, Pan C, Perez Olivares L, Winter J, Hackeng T, Karlsson MCI, Zeller T, Imhof A, Baron RM, Nicolaes GAF, Libby P, Maegdefessel L, Kamp F, Benoit M, Doring Y, Soehnlein O. Endotoxinemia Accelerates Atherosclerosis Through Electrostatic Charge-Mediated Monocyte Adhesion. Circulation 2021; 143(3): 254-266. https://www.ncbi.nlm.nih.gov/pubmed/33167684
- Sebag SC, Zhang Z, Qian Q, Li M, Zhu Z, Harata M, Li W, Zingman LV, Liu L, Lira VA, Potthoff MJ, Bartelt A, Yang L. ADH5-mediated NO bioactivity maintains metabolic homeostasis in brown adipose tissue. Cell Rep 2021; 37(7): 110003. https://www.ncbi.nlm.nih.gov/pubmed/34788615
- Shami A, Edsfeldt A, Bengtsson E, Nilsson J, Shore AC, Natali A, Khan F, Lutgens E, Goncalves I. Soluble CD40 Levels in Plasma Are Associated with Cardiovascular Disease and in Carotid Plaques with a Vulnerable Phenotype. J Stroke 2021; 23(3): 367-376. https://www.ncbi.nlm.nih.gov/pubmed/34649381
- Silvestre-Roig C, Lemnitzer P, Gall J, Schwager S, Toska A, Yvan-Charvet L, Detmar M, Soehnlein O. Arterial Delivery of VEGF-C Stabilizes Atherosclerotic Lesions. Circ Res 2021; 128(2): 284-286. https://www.ncbi.nlm.nih.gov/pubmed/33210556
- Soehnlein O, Libby P. Targeting inflammation in atherosclerosis - from experimental insights to the clinic. Nat Rev Drug Discov 2021; 20(8): 589-610. https://www.ncbi.nlm.nih.gov/pubmed/33976384
- Soltani-Fard E, Taghvimi S, Abedi Kichi Z, Weber C, Shabaninejad Z, Taheri-Anganeh M, Hossein Khatami S, Mousavi P, Movahedpour A, Natarelli L. Insights into the Function of Regulatory RNAs in Bacteria and Archaea. International Journal of Translational Medicine 2021; 1(3): 403-423. https://www.mdpi.com/2673-8937/1/3/24
- Sundararaman SS, Doring Y, van der Vorst EPC. PCSK9: A Multi-Faceted Protein That Is Involved in Cardiovascular Biology. Biomedicines 2021; 9(7). https://www.ncbi.nlm.nih.gov/pubmed/34356856
- Sundararaman SS, Peters LJF, Jansen Y, Gencer S, Yan Y, Nazir S, Bonnin Marquez A, Kahles F, Lehrke M, Biessen EAL, Jankowski J, Weber C, Doring Y, van der Vorst EPC. Adipocyte calcium sensing receptor is not involved in visceral adipose tissue inflammation or atherosclerosis development in hyperlipidemic Apoe(-/-) mice. Sci Rep 2021; 11(1): 10409. https://www.ncbi.nlm.nih.gov/pubmed/34001955
- Sundararaman SS, Peters LJF, Nazir S, Marquez AB, Bouma JE, Bayasgalan S, Doring Y, van der Vorst EPC. PCSK9 Imperceptibly Affects Chemokine Receptor Expression In Vitro and In Vivo. Int J Mol Sci 2021; 22(23). https://www.ncbi.nlm.nih.gov/pubmed/34884827
- Sundararaman SS, van der Vorst EPC. Calcium-Sensing Receptor (CaSR), Its Impact on Inflammation and the Consequences on Cardiovascular Health. Int J Mol Sci 2021; 22(5). https://www.ncbi.nlm.nih.gov/pubmed/33804544
- Tahir S, Steffens S. Nonclassical monocytes in cardiovascular physiology and disease. Am J Physiol Cell Physiol 2021; 320(5): C761-C770. https://www.ncbi.nlm.nih.gov/pubmed/33596150
- Thakur M, Evans B, Schindewolf M, Baumgartner I, Doring Y. Neutrophil Extracellular Traps Affecting Cardiovascular Health in Infectious and Inflammatory Diseases. Cells 2021; 10(7). https://www.ncbi.nlm.nih.gov/pubmed/34359859
- Totzeck M, Lutgens E, Neilan TG. Are we underestimating the potential for cardiotoxicity related to immune checkpoint inhibitors? Eur Heart J 2021; 42(16): 1632-1635. https://www.ncbi.nlm.nih.gov/pubmed/33291139
- Tsokanos FF, Muley C, Khani S, Hass D, Fleming T, Wolff G, Bartelt A, Nawroth P, Herzig S. Methylglyoxal Drives a Distinct, Nonclassical Macrophage Activation Status. Thromb Haemost 2021; 121(11): 1464-1475. https://www.ncbi.nlm.nih.gov/pubmed/33966256
- Tullemans BME, Karel MFA, Leopold V, Ten Brink MS, Baaten C, Maas SL, de Vos AF, Eble JA, Nijziel MR, van der Vorst EPC, Cosemans J, Heemskerk JWM, Claushuis TAM, Kuijpers MJE. Comparison of inhibitory effects of irreversible and reversible Btk inhibitors on platelet function. EJHaem 2021; 2(4): 685-699. https://www.ncbi.nlm.nih.gov/pubmed/35845214
- van der Bruggen MM, Reesink KD, Spronck PJM, Bitsch N, Hameleers J, Megens RTA, Schalkwijk CG, Delhaas T, Spronck B. An integrated set-up for ex vivo characterisation of biaxial murine artery biomechanics under pulsatile conditions. Sci Rep 2021; 11(1): 2671. https://www.ncbi.nlm.nih.gov/pubmed/33514757
- van der Laan KWF, Reesink KD, van der Bruggen MM, Jaminon AMG, Schurgers LJ, Megens RTA, Huberts W, Delhaas T, Spronck B. Improved Quantification of Cell Density in the Arterial Wall-A Novel Nucleus Splitting Approach Applied to 3D Two-Photon Laser-Scanning Microscopy. Front Physiol 2021; 12: 814434. https://www.ncbi.nlm.nih.gov/pubmed/35095571
- van der Vorst EPC. c-Kit inhibition: From promising cancer therapy to culprit in atherosclerosis. Atherosclerosis 2021; 324: 115-116. https://www.ncbi.nlm.nih.gov/pubmed/33824002
- van der Vorst EPC, Doring Y. Tracing Endothelial CXCR4 May Pave the Way for Localized Lesional Treatment Approaches. Arterioscler Thromb Vasc Biol 2021; 41(2): 837-838. https://www.ncbi.nlm.nih.gov/pubmed/33955781
- van der Vorst EPC, Pepe MAA, Peters LJF, Haberbosch M, Jansen Y, Naumann R, Stathopoulos GT, Weber C, Bidzhekov K. Transcriptome signature of miRNA-26b KO mouse model suggests novel targets. BMC Genom Data 2021; 22(1): 23. https://www.ncbi.nlm.nih.gov/pubmed/34193044
- van Leent MMT, Beldman TJ, Toner YC, Lameijer MA, Rother N, Bekkering S, Teunissen AJP, Zhou X, van der Meel R, Malkus J, Nauta SA, Klein ED, Fay F, Sanchez-Gaytan BL, Perez-Medina C, Kluza E, Ye YX, Wojtkiewicz G, Fisher EA, Swirski FK, Nahrendorf M, Zhang B, Li Y, Zhang B, Joosten LAB, Pasterkamp G, Boltjes A, Fayad ZA, Lutgens E, Netea MG, Riksen NP, Mulder WJM, Duivenvoorden R. Prosaposin mediates inflammation in atherosclerosis. Sci Transl Med 2021; 13(584). https://www.ncbi.nlm.nih.gov/pubmed/33692130
- van Niekerk E, Botha Le Roux S, Atzler D, Schwedhelm E, Boger RH, van Rooyen JM, Moss SJ, Mels CMC. Blood pressure and nitric oxide synthesis capacity in physically active and inactive groups: the SABPA study. J Hum Hypertens 2021; 35(4): 325-333. https://www.ncbi.nlm.nih.gov/pubmed/32382032
- van Os B, Lutgens E. SPARCing the clot. Blood 2021; 137(11): 1441-1442. https://www.ncbi.nlm.nih.gov/pubmed/33734343
- von Hundelshausen P, Lorenz R, Siess W, Weber C. Vaccine-Induced Immune Thrombotic Thrombocytopenia (VITT): Targeting Pathomechanisms with Bruton Tyrosine Kinase Inhibitors. Thromb Haemost 2021; 121(11): 1395-1399. https://www.ncbi.nlm.nih.gov/pubmed/33851389
- von Hundelshausen P, Siess W. Bleeding by Bruton Tyrosine Kinase-Inhibitors: Dependency on Drug Type and Disease. Cancers (Basel) 2021; 13(5). https://www.ncbi.nlm.nih.gov/pubmed/33806595
- von Hundelshausen P, Wichapong K, Gabius HJ, Mayo KH. The marriage of chemokines and galectins as functional heterodimers. Cell Mol Life Sci 2021; 78(24): 8073-8095. https://www.ncbi.nlm.nih.gov/pubmed/34767039
- Weber C, Rigby A, Lip GYH. Thrombosis and Haemostasis 2020 Editors' Choice Papers. Thromb Haemost 2021; 121(1): 109-114. https://www.ncbi.nlm.nih.gov/pubmed/33477198
- Weber C, von Hundelshausen P, Siess W. VITT after ChAdOx1 nCoV-19 Vaccination. N Engl J Med 2021; 385(23): 2203-2204. https://www.ncbi.nlm.nih.gov/pubmed/34731556
- Werth K, Hub E, Gutjahr JC, Bosjnak B, Zheng X, Bubke A, Russo S, Rot A, Forster R. Expression of ACKR4 demarcates the "peri-marginal sinus," a specialized vascular compartment of the splenic red pulp. Cell Rep 2021; 36(2): 109346. https://www.ncbi.nlm.nih.gov/pubmed/34260918
- Wichapong K, Silvestre-Roig C, Braster Q, Schumski A, Soehnlein O, Nicolaes GAF. Structure-based peptide design targeting intrinsically disordered proteins: Novel histone H4 and H2A peptidic inhibitors. Comput Struct Biotechnol J 2021; 19: 934-948. https://www.ncbi.nlm.nih.gov/pubmed/33598107
- Yan Y, Thakur M, van der Vorst EPC, Weber C, Doring Y. Targeting the chemokine network in atherosclerosis. Atherosclerosis 2021; 330: 95-106. https://www.ncbi.nlm.nih.gov/pubmed/34247863
- Yang Y, Tetti M, Vohra T, Adolf C, Seissler J, Hristov M, Belavgeni A, Bidlingmaier M, Linkermann A, Mulatero P, Beuschlein F, Reincke M, Williams TA. BEX1 Is Differentially Expressed in Aldosterone-Producing Adenomas and Protects Human Adrenocortical Cells From Ferroptosis. Hypertension 2021; 77(5): 1647-1658. https://www.ncbi.nlm.nih.gov/pubmed/33745298
- Yola IM, Moser C, Duncan MS, Schwedhelm E, Atzler D, Maas R, Hannemann J, Boger RH, Vasan RS, Xanthakis V. Associations of circulating dimethylarginines with the metabolic syndrome in the Framingham Offspring study. PLoS One 2021; 16(9): e0254577. https://www.ncbi.nlm.nih.gov/pubmed/34492019
- Adrover JM, Aroca-Crevillen A, Crainiciuc G, Ostos F, Rojas-Vega Y, Rubio-Ponce A, Cilloniz C, Bonzon-Kulichenko E, Calvo E, Rico D, Moro MA, Weber C, Lizasoain I, Torres A, Ruiz-Cabello J, Vazquez J, Hidalgo A. Programmed 'disarming' of the neutrophil proteome reduces the magnitude of inflammation. Nat Immunol 2020; 21(2): 135-144. https://www.ncbi.nlm.nih.gov/pubmed/31932813
- Aroca-Crevillen A, Adrover JM, Hidalgo A. Circadian Features of Neutrophil Biology. Front Immunol 2020; 11: 576. https://www.ncbi.nlm.nih.gov/pubmed/32346378
- Asare Y, Campbell-James TA, Bokov Y, Yu LL, Prestel M, El Bounkari O, Roth S, Megens RTA, Straub T, Thomas K, Yan G, Schneider M, Ziesch N, Tiedt S, Silvestre-Roig C, Braster Q, Huang Y, Schneider M, Malik R, Haffner C, Liesz A, Soehnlein O, Bernhagen J, Dichgans M. Histone Deacetylase 9 Activates IKK to Regulate Atherosclerotic Plaque Vulnerability. Circ Res 2020; 127(6): 811-823. https://www.ncbi.nlm.nih.gov/pubmed/32546048
- Baardman J, Lutgens E. Regulatory T Cell Metabolism in Atherosclerosis. Metabolites 2020; 10(7): 279. https://www.ncbi.nlm.nih.gov/pubmed/32650487
- Baardman J, Verberk SGS, van der Velden S, Gijbels MJJ, van Roomen C, Sluimer JC, Broos JY, Griffith GR, Prange KHM, van Weeghel M, Lakbir S, Molenaar D, Meinster E, Neele AE, Kooij G, de Vries HE, Lutgens E, Wellen KE, de Winther MPJ, Van den Bossche J. Macrophage ATP citrate lyase deficiency stabilizes atherosclerotic plaques. Nat Commun 2020; 11(1): 6296. https://www.ncbi.nlm.nih.gov/pubmed/33293558
- Baehr A, Hinkel R, Kupatt C. Statins Make a Difference in Acute Myocardial Infarction: A Revival. J Am Coll Cardiol 2020; 75(12): 1403-1405. https://www.ncbi.nlm.nih.gov/pubmed/32216908
- Baehr A, Umansky KB, Bassat E, Jurisch V, Klett K, Bozoglu T, Hornaschewitz N, Solyanik O, Kain D, Ferraro B, Cohen-Rabi R, Krane M, Cyran C, Soehnlein O, Laugwitz KL, Hinkel R, Kupatt C, Tzahor E. Agrin Promotes Coordinated Therapeutic Processes Leading to Improved Cardiac Repair in Pigs. Circulation 2020; 142(9): 868-881. https://www.ncbi.nlm.nih.gov/pubmed/32508131
- Ballesteros I, Rubio-Ponce A, Genua M, Lusito E, Kwok I, Fernandez-Calvo G, Khoyratty TE, van Grinsven E, Gonzalez-Hernandez S, Nicolas-Avila JA, Vicanolo T, Maccataio A, Benguria A, Li JL, Adrover JM, Aroca-Crevillen A, Quintana JA, Martin-Salamanca S, Mayo F, Ascher S, Barbiera G, Soehnlein O, Gunzer M, Ginhoux F, Sanchez-Cabo F, Nistal-Villan E, Schulz C, Dopazo A, Reinhardt C, Udalova IA, Ng LG, Ostuni R, Hidalgo A. Co-option of Neutrophil Fates by Tissue Environments. Cell 2020; 183(5): 1282-1297 e1218. https://www.ncbi.nlm.nih.gov/pubmed/33098771
- Bartelt A, Weber C. Mitochondrial Ejection for Cardiac Protection: The Macrophage Connection. Cell Metab 2020; 32(4): 512-513. https://www.ncbi.nlm.nih.gov/pubmed/33027673
- Bartelt A, Widenmaier SB. Proteostasis in thermogenesis and obesity. Biol Chem 2020; 401(9): 1019-1030. https://www.ncbi.nlm.nih.gov/pubmed/32061163
- Bosch L, de Haan JJ, Seijkens TTP, van Tiel CM, Brans MAD, Pasterkamp G, Lutgens E, de Jager SCA. The therapeutic potential of targeting CD40-TRAF6 pathway in cardiovascular Diseases. Int J Cardiol 2020; 300: 220. https://www.ncbi.nlm.nih.gov/pubmed/31928651
- Butt E, Stempfle K, Lister L, Wolf F, Kraft M, Herrmann AB, Viciano CP, Weber C, Hochhaus A, Ernst T, Hoffmann C, Zernecke A, Frietsch JJ. Phosphorylation-Dependent Differences in CXCR4-LASP1-AKT1 Interaction between Breast Cancer and Chronic Myeloid Leukemia. Cells 2020; 9(2): 444. https://www.ncbi.nlm.nih.gov/pubmed/32075106
- Chen HJ, Tas SW, de Winther MPJ. Type-I interferons in atherosclerosis. J Exp Med 2020; 217(1). https://www.ncbi.nlm.nih.gov/pubmed/31821440
- Cribbs AP, Terlecki-Zaniewicz S, Philpott M, Baardman J, Ahern D, Lindow M, Obad S, Oerum H, Sampey B, Mander PK, Penn H, Wordsworth P, Bowness P, de Winther M, Prinjha RK, Feldmann M, Oppermann U. Histone H3K27me3 demethylases regulate human Th17 cell development and effector functions by impacting on metabolism. Proc Natl Acad Sci U S A 2020; 117(11): 6056-6066. https://www.ncbi.nlm.nih.gov/pubmed/32123118
- d'Alessandro E, Becker C, Bergmeier W, Bode C, Bourne JH, Brown H, Buller HR, Ten Cate-Hoek AJ, Ten Cate V, van Cauteren YJM, Cheung YFH, Cleuren A, Coenen D, Crijns H, de Simone I, Dolleman SC, Klein CE, Fernandez DI, Granneman L, van THA, Henke P, Henskens YMC, Huang J, Jennings LK, Jooss N, Karel M, van den Kerkhof D, Klok FA, Kremers B, Lammle B, Leader A, Lundstrom A, Mackman N, Mannucci PM, Maqsood Z, van der Meijden PEJ, van Moorsel M, Moran LA, Morser J, van Mourik M, Navarro S, Neagoe RAI, Olie RH, van Paridon P, Posma J, Provenzale I, Reitsma PH, Scaf B, Schurgers L, Seelig J, Siegbahn A, Siegerink B, Soehnlein O, Soriano EM, Sowa MA, Spronk HMH, Storey RF, Tantiwong C, Veninga A, Wang X, Watson SP, Weitz J, Zeerleder SS, Ten Cate H, Scientific Reviewer C. Thrombo-Inflammation in Cardiovascular Disease: An Expert Consensus Document from the Third Maastricht Consensus Conference on Thrombosis. Thromb Haemost 2020; 120(4): 538-564. https://www.ncbi.nlm.nih.gov/pubmed/32289858
- Daub S, Lutgens E, Munzel T, Daiber A. CD40/CD40L and Related Signaling Pathways in Cardiovascular Health and Disease-The Pros and Cons for Cardioprotection. Int J Mol Sci 2020; 21(22): 8533. https://www.ncbi.nlm.nih.gov/pubmed/33198327
- Denisov SS, Heinzmann ACA, Vajen T, Vries MHM, Megens RTA, Suylen D, Koenen RR, Post MJ, Ippel JH, Hackeng TM, Dijkgraaf I. Tick Saliva Protein Evasin-3 Allows for Visualization of Inflammation in Arteries through Interactions with CXC-Type Chemokines Deposited on Activated Endothelium. Bioconjug Chem 2020; 31(3): 948-955. https://www.ncbi.nlm.nih.gov/pubmed/32077689
- Depuydt MAC, Prange KHM, Slenders L, Ord T, Elbersen D, Boltjes A, de Jager SCA, Asselbergs FW, de Borst GJ, Aavik E, Lonnberg T, Lutgens E, Glass CK, den Ruijter HM, Kaikkonen MU, Bot I, Slutter B, van der Laan SW, Yla-Herttuala S, Mokry M, Kuiper J, de Winther MPJ, Pasterkamp G. Microanatomy of the Human Atherosclerotic Plaque by Single-Cell Transcriptomics. Circ Res 2020; 127(11): 1437-1455. https://www.ncbi.nlm.nih.gov/pubmed/32981416
- Doring Y, Jansen Y, Cimen I, Aslani M, Gencer S, Peters LJF, Duchene J, Weber C, van der Vorst EPC. B-Cell-Specific CXCR4 Protects Against Atherosclerosis Development and Increases Plasma IgM Levels. Circ Res 2020; 126(6): 787-788. https://www.ncbi.nlm.nih.gov/pubmed/32078474
- Doring Y, Libby P, Soehnlein O. Neutrophil Extracellular Traps Participate in Cardiovascular Diseases: Recent Experimental and Clinical Insights. Circ Res 2020; 126(9): 1228-1241. https://www.ncbi.nlm.nih.gov/pubmed/32324499
- Doring Y, Noels H, van der Vorst E, Weber C. Seeing is repairing: how imaging-based timely interference with CXCR4 could improve repair after myocardial infarction. Eur Heart J 2020; 41(37): 3576-3578. https://www.ncbi.nlm.nih.gov/pubmed/32918455
- Dweck MR, Maurovich-Horvat P, Leiner T, Cosyns B, Fayad ZA, Gijsen FJH, Van der Heiden K, Kooi ME, Maehara A, Muller JE, Newby DE, Narula J, Pontone G, Regar E, Serruys PW, van der Steen AFW, Stone PH, Waltenberger JL, Yuan C, Evans PC, Lutgens E, Wentzel JJ, Back M. Contemporary rationale for non-invasive imaging of adverse coronary plaque features to identify the vulnerable patient: a Position Paper from the European Society of Cardiology Working Group on Atherosclerosis and Vascular Biology and the European Association of Cardiovascular Imaging. Eur Heart J Cardiovasc Imaging 2020; 21(11): 1177-1183. https://www.ncbi.nlm.nih.gov/pubmed/32887997
- Eckardt V, Miller MC, Blanchet X, Duan R, Leberzammer J, Duchene J, Soehnlein O, Megens RT, Ludwig AK, Dregni A, Faussner A, Wichapong K, Ippel H, Dijkgraaf I, Kaltner H, Doring Y, Bidzhekov K, Hackeng TM, Weber C, Gabius HJ, von Hundelshausen P, Mayo KH. Chemokines and galectins form heterodimers to modulate inflammation. EMBO Rep 2020; 21(4): e47852. https://www.ncbi.nlm.nih.gov/pubmed/32080959
- Evans PC, Rainger GE, Mason JC, Guzik TJ, Osto E, Stamataki Z, Neil D, Hoefer IE, Fragiadaki M, Waltenberger J, Weber C, Bochaton-Piallat ML, Back M. Endothelial dysfunction in COVID-19: a position paper of the ESC Working Group for Atherosclerosis and Vascular Biology, and the ESC Council of Basic Cardiovascular Science. Cardiovasc Res 2020; 116(14): 2177-2184. https://www.ncbi.nlm.nih.gov/pubmed/32750108
- Ferdinandy P, Koller A, Weber C, Waltenberger J. Postponement of Frontiers in Cardiovascular Biomedicine (FCVB) 2020 due to COVID-19: a look forward to 2021. Cardiovasc Res 2020; 116(7): e78-e81. https://www.ncbi.nlm.nih.gov/pubmed/32347928
- Franke K, Pillai SY, Hoogenboezem M, Gijbels MJJ, Matlung HL, Geissler J, Olsman H, Pottgens C, van Gorp PJ, Ozsvar-Kozma M, Saito Y, Matozaki T, Kuijpers TW, Hendriks RW, Kraal G, Binder CJ, de Winther MPJ, van den Berg TK. SIRPalpha on Mouse B1 Cells Restricts Lymphoid Tissue Migration and Natural Antibody Production. Front Immunol 2020; 11: 570963. https://www.ncbi.nlm.nih.gov/pubmed/33162986
- Gencer S, Lacy M, Atzler D, van der Vorst EPC, Doring Y, Weber C. Immunoinflammatory, Thrombohaemostatic, and Cardiovascular Mechanisms in COVID-19. Thromb Haemost 2020; 120(12): 1629-1641. https://www.ncbi.nlm.nih.gov/pubmed/33124029
- Gomez I, Ward B, Souilhol C, Recarti C, Ariaans M, Johnston J, Burnett A, Mahmoud M, Luong LA, West L, Long M, Parry S, Woods R, Hulston C, Benedikter B, Niespolo C, Bazaz R, Francis S, Kiss-Toth E, van Zandvoort M, Schober A, Hellewell P, Evans PC, Ridger V. Neutrophil microvesicles drive atherosclerosis by delivering miR-155 to atheroprone endothelium. Nat Commun 2020; 11(1): 214. https://www.ncbi.nlm.nih.gov/pubmed/31924781
- Greiffo FR, Viteri-Alvarez V, Frankenberger M, Dietel D, Ortega-Gomez A, Lee JS, Hilgendorff A, Behr J, Soehnlein O, Eickelberg O, Fernandez IE. CX3CR1-fractalkine axis drives kinetic changes of monocytes in fibrotic interstitial lung diseases. Eur Respir J 2020; 55(2). https://www.ncbi.nlm.nih.gov/pubmed/31744836
- Groeneweg L, Hidalgo A, N AG. Emerging roles of infiltrating granulocytes and monocytes in homeostasis. Cell Mol Life Sci 2020; 77(19): 3823-3830. https://www.ncbi.nlm.nih.gov/pubmed/32248248
- Hamid SM, Citir M, Terzi EM, Cimen I, Yildirim Z, Dogan AE, Kocaturk B, Onat UI, Arditi M, Weber C, Traynor-Kaplan A, Schultz C, Erbay E. Inositol-requiring enzyme-1 regulates phosphoinositide signaling lipids and macrophage growth. EMBO Rep 2020; 21(12): e51462. https://www.ncbi.nlm.nih.gov/pubmed/33140520
- Hinkel R, Ramanujam D, Kaczmarek V, Howe A, Klett K, Beck C, Dueck A, Thum T, Laugwitz KL, Maegdefessel L, Weber C, Kupatt C, Engelhardt S. AntimiR-21 Prevents Myocardial Dysfunction in a Pig Model of Ischemia/Reperfusion Injury. J Am Coll Cardiol 2020; 75(15): 1788-1800. https://www.ncbi.nlm.nih.gov/pubmed/32299591
- Karshovska E, Wei Y, Subramanian P, Mohibullah R, Geissler C, Baatsch I, Popal A, Corbalan Campos J, Exner N, Schober A. HIF-1alpha (Hypoxia-Inducible Factor-1alpha) Promotes Macrophage Necroptosis by Regulating miR-210 and miR-383. Arterioscler Thromb Vasc Biol 2020; 40(3): 583-596. https://www.ncbi.nlm.nih.gov/pubmed/31996026
- Kessler T, Schunkert H, von Hundelshausen P. Novel Approaches to Fine-Tune Therapeutic Targeting of Platelets in Atherosclerosis: A Critical Appraisal. Thromb Haemost 2020; 120(11): 1492-1504. https://www.ncbi.nlm.nih.gov/pubmed/32772352
- Kiouptsi K, Pontarollo G, Todorov H, Braun J, Jackel S, Koeck T, Bayer F, Karwot C, Karpi A, Gerber S, Jansen Y, Wild P, Ruf W, Daiber A, Van Der Vorst E, Weber C, Doring Y, Reinhardt C. Germ-free housing conditions do not affect aortic root and aortic arch lesion size of late atherosclerotic low-density lipoprotein receptor-deficient mice. Gut Microbes 2020; 11(6): 1809-1823. https://www.ncbi.nlm.nih.gov/pubmed/32579470
- Kontos C, El Bounkari O, Krammer C, Sinitski D, Hille K, Zan C, Yan G, Wang S, Gao Y, Brandhofer M, Megens RTA, Hoffmann A, Pauli J, Asare Y, Gerra S, Bourilhon P, Leng L, Eckstein HH, Kempf WE, Pelisek J, Gokce O, Maegdefessel L, Bucala R, Dichgans M, Weber C, Kapurniotu A, Bernhagen J. Designed CXCR4 mimic acts as a soluble chemokine receptor that blocks atherogenic inflammation by agonist-specific targeting. Nat Commun 2020; 11(1): 5981. https://www.ncbi.nlm.nih.gov/pubmed/33239628
- Kuznetsova T, Prange KHM, Glass CK, de Winther MPJ. Transcriptional and epigenetic regulation of macrophages in atherosclerosis. Nat Rev Cardiol 2020; 17(4): 216-228. https://www.ncbi.nlm.nih.gov/pubmed/31578516
- Lip GYH, Rigby A, Weber C. A Toast to the Last Decade and a Very Happy 2020 from Thrombosis and Haemostasis! Thromb Haemost 2020; 120(1): 1-4. https://www.ncbi.nlm.nih.gov/pubmed/31931535
- Lu HS, Schmidt AM, Hegele RA, Mackman N, Rader DJ, Weber C, Daugherty A. Annual Report on Sex in Preclinical Studies: Arteriosclerosis, Thrombosis, and Vascular Biology Publications in 2018. Arterioscler Thromb Vasc Biol 2020; 40(1): e1-e9. https://www.ncbi.nlm.nih.gov/pubmed/31869272
- Lutgens E. rs1883832: a CD40 single-nucleotide polymorphism for predicting coronary heart disease in humans. Cardiovasc Res 2020; 116(6): 1095-1096. https://www.ncbi.nlm.nih.gov/pubmed/31722420
- Lutgens E, Seijkens TTP. Cancer patients receiving immune checkpoint inhibitor therapy are at an increased risk for atherosclerotic cardiovascular disease. J Immunother Cancer 2020; 8(1). https://www.ncbi.nlm.nih.gov/pubmed/32034065
- Marquez AB, Nazir S, van der Vorst EPC. High-Density Lipoprotein Modifications: A Pathological Consequence or Cause of Disease Progression? Biomedicines 2020; 8(12): 549. https://www.ncbi.nlm.nih.gov/pubmed/33260660
- Nazir S, Jankowski V, Bender G, Zewinger S, Rye KA, van der Vorst EPC. Interaction between high-density lipoproteins and inflammation: Function matters more than concentration! Adv Drug Deliv Rev 2020; 159: 94-119. https://www.ncbi.nlm.nih.gov/pubmed/33080259
- Neele AE, Chen HJ, Gijbels MJJ, van der Velden S, Hoeksema MA, Boshuizen MCS, Van den Bossche J, Tool AT, Matlung HL, van den Berg TK, Lutgens E, de Winther MPJ. Myeloid Ezh2 Deficiency Limits Atherosclerosis Development. Front Immunol 2020; 11: 594603. https://www.ncbi.nlm.nih.gov/pubmed/33574814
- Ortega-Gomez A, Soehnlein O. Lack of Proteinase 3 Stabilizes Advanced Atherosclerotic Lesions. Thromb Haemost 2020; 120(6): 994-997. https://www.ncbi.nlm.nih.gov/pubmed/32403136
- Peters LJF, Biessen EAL, Hohl M, Weber C, van der Vorst EPC, Santovito D. Small Things Matter: Relevance of MicroRNAs in Cardiovascular Disease. Front Physiol 2020; 11: 793. https://www.ncbi.nlm.nih.gov/pubmed/32733281
- Peters LJF, Floege J, Biessen EAL, Jankowski J, van der Vorst EPC. MicroRNAs in Chronic Kidney Disease: Four Candidates for Clinical Application. Int J Mol Sci 2020; 21(18). https://www.ncbi.nlm.nih.gov/pubmed/32906849
- Poels K, Schnitzler JG, Waissi F, Levels JHM, Stroes ESG, Daemen M, Lutgens E, Pennekamp AM, De Kleijn DPV, Seijkens TTP, Kroon J. Inhibition of PFKFB3 Hampers the Progression of Atherosclerosis and Promotes Plaque Stability. Front Cell Dev Biol 2020; 8: 581641. https://www.ncbi.nlm.nih.gov/pubmed/33282864
- Poels K, van Leent MMT, Boutros C, Tissot H, Roy S, Meerwaldt AE, Toner YCA, Reiche ME, Kusters PJH, Malinova T, Huveneers S, Kaufman AE, Mani V, Fayad ZA, de Winther MPJ, Marabelle A, Mulder WJM, Robert C, Seijkens TTP, Lutgens E. Immune Checkpoint Inhibitor Therapy Aggravates T Cell-Driven Plaque Inflammation in Atherosclerosis. JACC CardioOncol 2020; 2(4): 599-610. https://www.ncbi.nlm.nih.gov/pubmed/34396271
- Poels K, van Leent MMT, Reiche ME, Kusters PJH, Huveneers S, de Winther MPJ, Mulder WJM, Lutgens E, Seijkens TTP. Antibody-Mediated Inhibition of CTLA4 Aggravates Atherosclerotic Plaque Inflammation and Progression in Hyperlipidemic Mice. Cells 2020; 9(9). https://www.ncbi.nlm.nih.gov/pubmed/32872393
- Poels K, Vos WG, Lutgens E, Seijkens TTP. E3 Ubiquitin Ligases as Immunotherapeutic Target in Atherosclerotic Cardiovascular Disease. Front Cardiovasc Med 2020; 7: 106. https://www.ncbi.nlm.nih.gov/pubmed/32582770
- Priem B, van Leent MMT, Teunissen AJP, Sofias AM, Mourits VP, Willemsen L, Klein ED, Oosterwijk RS, Meerwaldt AE, Munitz J, Prevot G, Vera Verschuur A, Nauta SA, van Leeuwen EM, Fisher EL, de Jong KAM, Zhao Y, Toner YC, Soultanidis G, Calcagno C, Bomans PHH, Friedrich H, Sommerdijk N, Reiner T, Duivenvoorden R, Zupancic E, Di Martino JS, Kluza E, Rashidian M, Ploegh HL, Dijkhuizen RM, Hak S, Perez-Medina C, Bravo-Cordero JJ, de Winther MPJ, Joosten LAB, van Elsas A, Fayad ZA, Rialdi A, Torre D, Guccione E, Ochando J, Netea MG, Griffioen AW, Mulder WJM. Trained Immunity-Promoting Nanobiologic Therapy Suppresses Tumor Growth and Potentiates Checkpoint Inhibition. Cell 2020; 183(3): 786-801 e719. https://www.ncbi.nlm.nih.gov/pubmed/33125893
- Puhl SL. Cannabinoid-sensitive receptors in cardiac physiology and ischaemia. Biochim Biophys Acta Mol Cell Res 2020; 1867(3): 118462. https://www.ncbi.nlm.nih.gov/pubmed/30890410
- Remie CME, Roumans KHM, Moonen MPB, Connell NJ, Havekes B, Mevenkamp J, Lindeboom L, de Wit VHW, van de Weijer T, Aarts S, Lutgens E, Schomakers BV, Elfrink HL, Zapata-Perez R, Houtkooper RH, Auwerx J, Hoeks J, Schrauwen-Hinderling VB, Phielix E, Schrauwen P. Nicotinamide riboside supplementation alters body composition and skeletal muscle acetylcarnitine concentrations in healthy obese humans. Am J Clin Nutr 2020; 112(2): 413-426. https://www.ncbi.nlm.nih.gov/pubmed/32320006
- Rigby A, Lip GYH, Weber C. Documenting Sex and Sex Differences in Animal Studies. Thromb Haemost 2020; 120(6): 879-882. https://www.ncbi.nlm.nih.gov/pubmed/32369833
- Saar-Kovrov V, Donners M, van der Vorst EPC. Shedding of Klotho: Functional Implications in Chronic Kidney Disease and Associated Vascular Disease. Front Cardiovasc Med 2020; 7: 617842. https://www.ncbi.nlm.nih.gov/pubmed/33585584
- Sanchez-Diaz M, Nicolas-Avila JA, Cordero MD, Hidalgo A. Mitochondrial Adaptations in the Growing Heart. Trends Endocrinol Metab 2020; 31(4): 308-319. https://www.ncbi.nlm.nih.gov/pubmed/32035734
- Santovito D. From Beneficial to Detrimental: How Nicotine Hijacks the Autophagy Machinery. Arterioscler Thromb Vasc Biol 2020; 40(9): 1955-1957. https://www.ncbi.nlm.nih.gov/pubmed/32845772
- Santovito D, Egea V, Bidzhekov K, Natarelli L, Mourao A, Blanchet X, Wichapong K, Aslani M, Brunssen C, Horckmans M, Hristov M, Geerlof A, Lutgens E, Daemen M, Hackeng T, Ries C, Chavakis T, Morawietz H, Naumann R, Hundelshausen PV, Steffens S, Duchene J, Megens RTA, Sattler M, Weber C. Autophagy unleashes noncanonical microRNA functions. Autophagy 2020; 16(12): 2294-2296. https://www.ncbi.nlm.nih.gov/pubmed/33054575
- Santovito D, Egea V, Bidzhekov K, Natarelli L, Mourao A, Blanchet X, Wichapong K, Aslani M, Brunssen C, Horckmans M, Hristov M, Geerlof A, Lutgens E, Daemen M, Hackeng T, Ries C, Chavakis T, Morawietz H, Naumann R, von Hundelshausen P, Steffens S, Duchene J, Megens RTA, Sattler M, Weber C. Noncanonical inhibition of caspase-3 by a nuclear microRNA confers endothelial protection by autophagy in atherosclerosis. Sci Transl Med 2020; 12(546). https://www.ncbi.nlm.nih.gov/pubmed/32493793
- Santovito D, Marcantonio P, Mastroiacovo D, Natarelli L, Mandolini C, De Nardis V, Paganelli C, De Cesare D, Affaitati G, Giamberardino MA, Stellin L, Pinelli M, Weber C, De Blasis G, Occhiuzzi U, Bucci M, Desideri G, Cipollone F. High dose rosuvastatin increases ABCA1 transporter in human atherosclerotic plaques in a cholesterol-independent fashion. Int J Cardiol 2020; 299: 249-253. https://www.ncbi.nlm.nih.gov/pubmed/31409515
- Schilperoort M, van den Berg R, Bosmans LA, van Os BW, Dolle MET, Smits NAM, Guichelaar T, van Baarle D, Koemans L, Berbee JFP, Deboer T, Meijer JH, de Vries MR, Vreeken D, van Gils JM, Willems van Dijk K, van Kerkhof LWM, Lutgens E, Biermasz NR, Rensen PCN, Kooijman S. Disruption of circadian rhythm by alternating light-dark cycles aggravates atherosclerosis development in APOE*3-Leiden.CETP mice. J Pineal Res 2020; 68(1): e12614. https://www.ncbi.nlm.nih.gov/pubmed/31599473
- Schnitzler JG, Hoogeveen RM, Ali L, Prange KHM, Waissi F, van Weeghel M, Bachmann JC, Versloot M, Borrelli MJ, Yeang C, De Kleijn DPV, Houtkooper RH, Koschinsky ML, de Winther MPJ, Groen AK, Witztum JL, Tsimikas S, Stroes ESG, Kroon J. Atherogenic Lipoprotein(a) Increases Vascular Glycolysis, Thereby Facilitating Inflammation and Leukocyte Extravasation. Circ Res 2020; 126(10): 1346-1359. https://www.ncbi.nlm.nih.gov/pubmed/32160811
- Schnitzler JG, Poels K, Stiekema LCA, Yeang C, Tsimikas S, Kroon J, Stroes ESG, Lutgens E, Seijkens TTP. Short-term regulation of hematopoiesis by lipoprotein(a) results in the production of pro-inflammatory monocytes. Int J Cardiol 2020; 315: 81-85. https://www.ncbi.nlm.nih.gov/pubmed/32387421
- Serhan CN, Gupta SK, Perretti M, Godson C, Brennan E, Li Y, Soehnlein O, Shimizu T, Werz O, Chiurchiu V, Azzi A, Dubourdeau M, Gupta SS, Schopohl P, Hoch M, Gjorgevikj D, Khan FM, Brauer D, Tripathi A, Cesnulevicius K, Lescheid D, Schultz M, Sarndahl E, Repsilber D, Kruse R, Sala A, Haeggstrom JZ, Levy BD, Filep JG, Wolkenhauer O. The Atlas of Inflammation Resolution (AIR). Mol Aspects Med 2020; 74: 100894. https://www.ncbi.nlm.nih.gov/pubmed/32893032
- Shami A, Atzler D, Bosmans LA, Winkels H, Meiler S, Lacy M, van Tiel C, Ta Megens R, Nitz K, Baardman J, Kusters P, Seijkens T, Buerger C, Janjic A, Riccardi C, Edsfeldt A, Monaco C, Daemen M, de Winther MPJ, Nilsson J, Weber C, Gerdes N, Goncalves I, Lutgens E. Glucocorticoid-induced tumour necrosis factor receptor family-related protein (GITR) drives atherosclerosis in mice and is associated with an unstable plaque phenotype and cerebrovascular events in humans. Eur Heart J 2020; 41(31): 2938-2948. https://www.ncbi.nlm.nih.gov/pubmed/32728688
- Siess W, Hundelshausen PV, Lorenz R. Selective inhibition of thromboinflammation in COVID-19 by Btk inhibitors. Platelets 2020; 31(8): 989-992. https://www.ncbi.nlm.nih.gov/pubmed/32892684
- Silvestre-Roig C, Braster Q, Ortega-Gomez A, Soehnlein O. Neutrophils as regulators of cardiovascular inflammation. Nat Rev Cardiol 2020; 17(6): 327-340. https://www.ncbi.nlm.nih.gov/pubmed/31996800
- Steffens S, Van Linthout S, Sluijter JPG, Tocchetti CG, Thum T, Madonna R. Stimulating pro-reparative immune responses to prevent adverse cardiac remodelling: consensus document from the joint 2019 meeting of the ESC Working Groups of cellular biology of the heart and myocardial function. Cardiovasc Res 2020; 116(11): 1850-1862. https://www.ncbi.nlm.nih.gov/pubmed/32396608
- Sternkopf M, Nagy M, Baaten C, Kuijpers MJE, Tullemans BME, Wirth J, Theelen W, Mastenbroek TG, Lehrke M, Winnerling B, Baerts L, Marx N, De Meester I, Doring Y, Cosemans J, Daiber A, Steven S, Jankowski J, Heemskerk JWM, Noels H. Native, Intact Glucagon-Like Peptide 1 Is a Natural Suppressor of Thrombus Growth Under Physiological Flow Conditions. Arterioscler Thromb Vasc Biol 2020; 40(3): e65-e77. https://www.ncbi.nlm.nih.gov/pubmed/31893947
- Stiekema LCA, Prange KHM, Hoogeveen RM, Verweij SL, Kroon J, Schnitzler JG, Dzobo KE, Cupido AJ, Tsimikas S, Stroes ESG, de Winther MPJ, Bahjat M. Potent lipoprotein(a) lowering following apolipoprotein(a) antisense treatment reduces the pro-inflammatory activation of circulating monocytes in patients with elevated lipoprotein(a). Eur Heart J 2020; 41(24): 2262-2271. https://www.ncbi.nlm.nih.gov/pubmed/32268367
- Thiem K, Hoeke G, Zhou E, Hijmans A, Houben T, Boels MG, Mol IM, Lutgens E, Shiri-Sverdlov R, Bussink J, Kanneganti TD, Boon MR, Stienstra R, Tack CJ, Rensen PC, Netea MG, Berbee JF, van Diepen JA. Deletion of haematopoietic Dectin-2 or CARD9 does not protect from atherosclerosis development under hyperglycaemic conditions. Diab Vasc Dis Res 2020; 17(1): 1479164119892140. https://www.ncbi.nlm.nih.gov/pubmed/31868000
- Tilstam PV, Soppert J, Hemmers C, Harlacher E, Doring Y, van der Vorst EPC, Schulte C, Alampour-Rajabi S, Theelen W, Asare Y, de Winther MPJ, Lawrence T, Bernhagen J, Schober A, Zernecke A, Jankowski J, Weber C, Noels H. Non-activatable mutant of inhibitor of kappa B kinase alpha (IKKalpha) exerts vascular site-specific effects on atherosclerosis in Apoe-deficient mice. Atherosclerosis 2020; 292: 23-30. https://www.ncbi.nlm.nih.gov/pubmed/31733453
- van der Vorst EPC. High-Density Lipoproteins and Apolipoprotein A1. Subcell Biochem 2020; 94: 399-420. https://www.ncbi.nlm.nih.gov/pubmed/32189309
- van der Vorst EPC, Biessen EAL, Donners M. Letter by van der Vorst et al Regarding Article, "Anti-Inflammatory Effects of HDL (High-Density Lipoprotein) in Macrophages Predominate Over Proinflammatory Effects in Atherosclerotic Plaques". Arterioscler Thromb Vasc Biol 2020; 40(2): e31-e32. https://www.ncbi.nlm.nih.gov/pubmed/31967904
- van der Vorst EPC, Daissormont I, Aslani M, Seijkens T, Wijnands E, Lutgens E, Duchene J, Santovito D, Doring Y, Halvorsen B, Aukrust P, Weber C, Hopken UE, Biessen EAL. Interruption of the CXCL13/CXCR5 Chemokine Axis Enhances Plasma IgM Levels and Attenuates Atherosclerosis Development. Thromb Haemost 2020; 120(2): 344-347. https://www.ncbi.nlm.nih.gov/pubmed/31837653
- Weber C. The ESC Council on Basic Cardiovascular Science. Eur Heart J 2020; 41(12): 1227-1230. https://www.ncbi.nlm.nih.gov/pubmed/32198920
- Weber C, Rigby A, Lip GYH. Thrombosis and Haemostasis 2019 Editor's Choice Papers. Thromb Haemost 2020; 120(1): 184-190. https://www.ncbi.nlm.nih.gov/pubmed/31931536
- Willemsen L, de Winther MP. Macrophage subsets in atherosclerosis as defined by single-cell technologies. J Pathol 2020; 250(5): 705-714. https://www.ncbi.nlm.nih.gov/pubmed/32003464
- Zernecke A, Winkels H, Cochain C, Williams JW, Wolf D, Soehnlein O, Robbins CS, Monaco C, Park I, McNamara CA, Binder CJ, Cybulsky MI, Scipione CA, Hedrick CC, Galkina EV, Kyaw T, Ghosheh Y, Dinh HQ, Ley K. Meta-Analysis of Leukocyte Diversity in Atherosclerotic Mouse Aortas. Circ Res 2020; 127(3): 402-426. https://www.ncbi.nlm.nih.gov/pubmed/32673538
- Zhang D, Ebrahim M, Adler K, Blanchet X, Jamasbi J, Megens RTA, Uhland K, Ungerer M, Munch G, Deckmyn H, Weber C, Elia N, Lorenz R, Siess W. Glycoprotein VI is not a Functional Platelet Receptor for Fibrin Formed in Plasma or Blood. Thromb Haemost 2020; 120(6): 977-993. https://www.ncbi.nlm.nih.gov/pubmed/32492725
- Aarts S, Reiche M, den Toom M, Gijbels M, Beckers L, Gerdes N, Lutgens E. Depletion of CD40 on CD11c(+) cells worsens the metabolic syndrome and ameliorates hepatic inflammation during NASH. Sci Rep 2019; 9(1): 14702. https://www.ncbi.nlm.nih.gov/pubmed/31604965
- Aarts SA, Seijkens TT, Kusters PJ, van Tiel CM, Reiche ME, den Toom M, Beckers L, van Roomen CP, de Winther MP, Kooij G, Lutgens E. Macrophage CD40 signaling drives experimental autoimmune encephalomyelitis. J Pathol 2019; 247(4): 471-480. https://www.ncbi.nlm.nih.gov/pubmed/30471110
- Adrover JM, Del Fresno C, Crainiciuc G, Cuartero MI, Casanova-Acebes M, Weiss LA, Huerga-Encabo H, Silvestre-Roig C, Rossaint J, Cossio I, Lechuga-Vieco AV, Garcia-Prieto J, Gomez-Parrizas M, Quintana JA, Ballesteros I, Martin-Salamanca S, Aroca-Crevillen A, Chong SZ, Evrard M, Balabanian K, Lopez J, Bidzhekov K, Bachelerie F, Abad-Santos F, Munoz-Calleja C, Zarbock A, Soehnlein O, Weber C, Ng LG, Lopez-Rodriguez C, Sancho D, Moro MA, Ibanez B, Hidalgo A. A Neutrophil Timer Coordinates Immune Defense and Vascular Protection. Immunity 2019; 50(2): 390-402 e310. https://www.ncbi.nlm.nih.gov/pubmed/30709741
- Bartelt A, Leipsic J, Weber C. The new age of radiomic risk profiling: perivascular fat at the heart of the matter. Eur Heart J 2019; 40(43): 3544-3546. https://www.ncbi.nlm.nih.gov/pubmed/31605139
- Bekkering S, Stiekema LCA, Bernelot Moens S, Verweij SL, Novakovic B, Prange K, Versloot M, Roeters van Lennep JE, Stunnenberg H, de Winther M, Stroes ESG, Joosten LAB, Netea MG, Riksen NP. Treatment with Statins Does Not Revert Trained Immunity in Patients with Familial Hypercholesterolemia. Cell Metab 2019; 30(1): 1-2. https://www.ncbi.nlm.nih.gov/pubmed/31204280
- Beldman TJ, Malinova TS, Desclos E, Grootemaat AE, Misiak ALS, van der Velden S, van Roomen C, Beckers L, van Veen HA, Krawczyk PM, Hoebe RA, Sluimer JC, Neele AE, de Winther MPJ, van der Wel NN, Lutgens E, Mulder WJM, Huveneers S, Kluza E. Nanoparticle-Aided Characterization of Arterial Endothelial Architecture during Atherosclerosis Progression and Metabolic Therapy. ACS Nano 2019; 13(12): 13759-13774. https://www.ncbi.nlm.nih.gov/pubmed/31268670
- Bianchini M, Duchene J, Santovito D, Schloss MJ, Evrard M, Winkels H, Aslani M, Mohanta SK, Horckmans M, Blanchet X, Lacy M, von Hundelshausen P, Atzler D, Habenicht A, Gerdes N, Pelisek J, Ng LG, Steffens S, Weber C, Megens RTA. PD-L1 expression on nonclassical monocytes reveals their origin and immunoregulatory function. Sci Immunol 2019; 4(36). https://www.ncbi.nlm.nih.gov/pubmed/31227596
- Bijnen M, van de Gaar J, Vroomen M, Gijbels MJ, de Winther M, Schalkwijk CG, Wouters K. Adipose tissue macrophages do not affect atherosclerosis development in mice. Atherosclerosis 2019; 281: 31-37. https://www.ncbi.nlm.nih.gov/pubmed/30654169
- Boeltz S, Amini P, Anders HJ, Andrade F, Bilyy R, Chatfield S, Cichon I, Clancy DM, Desai J, Dumych T, Dwivedi N, Gordon RA, Hahn J, Hidalgo A, Hoffmann MH, Kaplan MJ, Knight JS, Kolaczkowska E, Kubes P, Leppkes M, Manfredi AA, Martin SJ, Maueroder C, Maugeri N, Mitroulis I, Munoz LE, Nakazawa D, Neeli I, Nizet V, Pieterse E, Radic MZ, Reinwald C, Ritis K, Rovere-Querini P, Santocki M, Schauer C, Schett G, Shlomchik MJ, Simon HU, Skendros P, Stojkov D, Vandenabeele P, Berghe TV, van der Vlag J, Vitkov L, von Kockritz-Blickwede M, Yousefi S, Zarbock A, Herrmann M. To NET or not to NET:current opinions and state of the science regarding the formation of neutrophil extracellular traps. Cell Death Differ 2019; 26(3): 395-408. https://www.ncbi.nlm.nih.gov/pubmed/30622307
- Bollenbach A, Cordts K, Hanff E, Atzler D, Choe CU, Schwedhelm E, Tsikas D. Evidence by GC-MS that lysine is an arginase-catalyzed metabolite of homoarginine in vitro and in vivo in humans. Anal Biochem 2019; 577: 59-66. https://www.ncbi.nlm.nih.gov/pubmed/31028716
- Bongiovanni D, Santamaria G, Klug M, Santovito D, Felicetta A, Hristov M, von Scheidt M, Aslani M, Cibella J, Weber C, Moretti A, Laugwitz KL, Peano C, Bernlochner I. Transcriptome Analysis of Reticulated Platelets Reveals a Prothrombotic Profile. Thromb Haemost 2019; 119(11): 1795-1806. https://www.ncbi.nlm.nih.gov/pubmed/31473989
- Bosch L, de Haan J, Seijkens T, van Tiel C, Brans M, Pasterkamp G, Lutgens E, de Jager S. Small molecule-mediated inhibition of CD40-TRAF6 reduces adverse cardiac remodelling in pressure overload induced heart failure. Int J Cardiol 2019; 279: 141-144. https://www.ncbi.nlm.nih.gov/pubmed/30612848
- Brandsma E, Kloosterhuis NJ, Koster M, Dekker DC, Gijbels MJJ, van der Velden S, Rios-Morales M, van Faassen MJR, Loreti MG, de Bruin A, Fu J, Kuipers F, Bakker BM, Westerterp M, de Winther MPJ, Hofker MH, van de Sluis B, Koonen DPY. A Proinflammatory Gut Microbiota Increases Systemic Inflammation and Accelerates Atherosclerosis. Circ Res 2019; 124(1): 94-100. https://www.ncbi.nlm.nih.gov/pubmed/30582442
- Busygina K, Denzinger V, Bernlochner I, Weber C, Lorenz R, Siess W. Btk Inhibitors as First Oral Atherothrombosis-Selective Antiplatelet Drugs? Thromb Haemost 2019; 119(8): 1212-1221. https://www.ncbi.nlm.nih.gov/pubmed/31087308
- Cassatella MA, Ostberg NK, Tamassia N, Soehnlein O. Biological Roles of Neutrophil-Derived Granule Proteins and Cytokines. Trends Immunol 2019; 40(7): 648-664. https://www.ncbi.nlm.nih.gov/pubmed/31155315
- Centa M, Jin H, Hofste L, Hellberg S, Busch A, Baumgartner R, Verzaal NJ, Lind Enoksson S, Perisic Matic L, Boddul SV, Atzler D, Li DY, Sun C, Hansson GK, Ketelhuth DFJ, Hedin U, Wermeling F, Lutgens E, Binder CJ, Maegdesfessel L, Malin SG. Germinal Center-Derived Antibodies Promote Atherosclerosis Plaque Size and Stability. Circulation 2019; 139(21): 2466-2482. https://www.ncbi.nlm.nih.gov/pubmed/30894016
- Chen HJ, Li Yim AYF, Griffith GR, de Jonge WJ, Mannens M, Ferrero E, Henneman P, de Winther MPJ. Meta-Analysis of in vitro-Differentiated Macrophages Identifies Transcriptomic Signatures That Classify Disease Macrophages in vivo. Front Immunol 2019; 10: 2887. https://www.ncbi.nlm.nih.gov/pubmed/31921150
- Chen PY, Qin L, Li G, Wang Z, Dahlman JE, Malagon-Lopez J, Gujja S, Cilfone NA, Kauffman KJ, Sun L, Sun H, Zhang X, Aryal B, Canfran-Duque A, Liu R, Kusters P, Sehgal A, Jiao Y, Anderson DG, Gulcher J, Fernandez-Hernando C, Lutgens E, Schwartz MA, Pober JS, Chittenden TW, Tellides G, Simons M. Endothelial TGF-beta signalling drives vascular inflammation and atherosclerosis. Nat Metab 2019; 1(9): 912-926. https://www.ncbi.nlm.nih.gov/pubmed/31572976
- Ciato D, Li R, Monteserin Garcia JL, Papst L, D'Annunzio S, Hristov M, Tichomirowa MA, Belaya Z, Rozhinskaya L, Buchfelder M, Theodoropoulou M, Paez-Pereda M, Stalla GK. Inhibition of Heat Shock Factor 1 Enhances Repressive Molecular Mechanisms on the POMC Promoter. Neuroendocrinology 2019; 109(4): 362-373. https://www.ncbi.nlm.nih.gov/pubmed/30995664
- Cimen I, Yildirim Z, Dogan AE, Yildirim AD, Tufanli O, Onat UI, Nguyen U, Watkins SM, Weber C, Erbay E. Double bond configuration of palmitoleate is critical for atheroprotection. Mol Metab 2019; 28: 58-72. https://www.ncbi.nlm.nih.gov/pubmed/31422082
- Cordts K, Grzybowski R, Lezius S, Luneburg N, Atzler D, Neu A, Hornig S, Boger RH, Gerloff C, Magnus T, Thomalla G, Schwedhelm E, Grant PJ, Choe CU. Guanidino compound ratios are associated with stroke etiology, internal carotid artery stenosis and CHA(2)DS(2)-VASc score in three cross-sectional studies. J Neurol Sci 2019; 397: 156-161. https://www.ncbi.nlm.nih.gov/pubmed/30640152
- Cossio I, Lucas D, Hidalgo A. Neutrophils as regulators of the hematopoietic niche. Blood 2019; 133(20): 2140-2148. https://www.ncbi.nlm.nih.gov/pubmed/30898859
- Cremer S, Michalik KM, Fischer A, Pfisterer L, Jae N, Winter C, Boon RA, Muhly-Reinholz M, John D, Uchida S, Weber C, Poller W, Gunther S, Braun T, Li DY, Maegdefessel L, Perisic Matic L, Hedin U, Soehnlein O, Zeiher A, Dimmeler S. Hematopoietic Deficiency of the Long Noncoding RNA MALAT1 Promotes Atherosclerosis and Plaque Inflammation. Circulation 2019; 139(10): 1320-1334. https://www.ncbi.nlm.nih.gov/pubmed/30586743
- de Juan A, Ince LM, Pick R, Chen CS, Molica F, Zuchtriegel G, Wang C, Zhang D, Druzd D, Hessenauer MET, Pelli G, Kolbe I, Oster H, Prophete C, Hergenhan SM, Albrecht U, Ripperger J, Montanez E, Reichel CA, Soehnlein O, Kwak BR, Frenette PS, Scheiermann C. Artery-Associated Sympathetic Innervation Drives Rhythmic Vascular Inflammation of Arteries and Veins. Circulation 2019; 140(13): 1100-1114. https://www.ncbi.nlm.nih.gov/pubmed/31401849
- de Winther MPJ, Dallinga-Thie GM. Introduction to the thematic review series on different levels of genetic regulation of cardiovascular disease. Atherosclerosis 2019; 281: 148-149. https://www.ncbi.nlm.nih.gov/pubmed/30658843
- de Winther MPJ, Glass CK. Leducq Epigenetics of Atherosclerosis Network. Circ Res 2019; 124(12): 1697-1700. https://www.ncbi.nlm.nih.gov/pubmed/31170047
- de Winther MPJ, Lutgens E. The Link between Hematopoiesis and Atherosclerosis. N Engl J Med 2019; 380(19): 1869-1871. https://www.ncbi.nlm.nih.gov/pubmed/31067380
- Dekkers KF, Neele AE, Jukema JW, Heijmans BT, de Winther MPJ. Human monocyte-to-macrophage differentiation involves highly localized gain and loss of DNA methylation at transcription factor binding sites. Epigenetics Chromatin 2019; 12(1): 34. https://www.ncbi.nlm.nih.gov/pubmed/31171035
- Denisov SS, Ippel JH, Heinzmann ACA, Koenen RR, Ortega-Gomez A, Soehnlein O, Hackeng TM, Dijkgraaf I. Tick saliva protein Evasin-3 modulates chemotaxis by disrupting CXCL8 interactions with glycosaminoglycans and CXCR2. J Biol Chem 2019; 294(33): 12370-12379. https://www.ncbi.nlm.nih.gov/pubmed/31235521
- Denzinger V, Busygina K, Jamasbi J, Pekrul I, Spannagl M, Weber C, Lorenz R, Siess W. Optimizing Platelet GPVI Inhibition versus Haemostatic Impairment by the Btk Inhibitors Ibrutinib, Acalabrutinib, ONO/GS-4059, BGB-3111 and Evobrutinib. Thromb Haemost 2019; 119(3): 397-406. https://www.ncbi.nlm.nih.gov/pubmed/30685871
- Doring Y, van der Vorst EPC, Duchene J, Jansen Y, Gencer S, Bidzhekov K, Atzler D, Santovito D, Rader DJ, Saleheen D, Weber C. CXCL12 Derived From Endothelial Cells Promotes Atherosclerosis to Drive Coronary Artery Disease. Circulation 2019; 139(10): 1338-1340. https://www.ncbi.nlm.nih.gov/pubmed/30865486
- Eckardt V, Weber C, von Hundelshausen P. Glycans and Glycan-Binding Proteins in Atherosclerosis. Thromb Haemost 2019; 119(8): 1265-1273. https://www.ncbi.nlm.nih.gov/pubmed/31266083
- Erdogmus S, Storch U, Danner L, Becker J, Winter M, Ziegler N, Wirth A, Offermanns S, Hoffmann C, Gudermann T, Mederos YSM. Helix 8 is the essential structural motif of mechanosensitive GPCRs. Nat Commun 2019; 10(1): 5784. https://www.ncbi.nlm.nih.gov/pubmed/31857598
- Ferraro B, Leoni G, Hinkel R, Ormanns S, Paulin N, Ortega-Gomez A, Viola JR, de Jong R, Bongiovanni D, Bozoglu T, Maas SL, D'Amico M, Kessler T, Zeller T, Hristov M, Reutelingsperger C, Sager HB, Doring Y, Nahrendorf M, Kupatt C, Soehnlein O. Pro-Angiogenic Macrophage Phenotype to Promote Myocardial Repair. J Am Coll Cardiol 2019; 73(23): 2990-3002. https://www.ncbi.nlm.nih.gov/pubmed/31196457
- Fisslthaler B, Zippel N, Abdel Malik R, Delgado Lagos F, Zukunft S, Thoele J, Siuda D, Soehnlein O, Wittig I, Heidler J, Weigert A, Fleming I. Myeloid-Specific Deletion of the AMPKalpha2 Subunit Alters Monocyte Protein Expression and Atherogenesis. Int J Mol Sci 2019; 20(12): 3005. https://www.ncbi.nlm.nih.gov/pubmed/31248224
- Garcia-Culebras A, Duran-Laforet V, Pena-Martinez C, Moraga A, Ballesteros I, Cuartero MI, de la Parra J, Palma-Tortosa S, Hidalgo A, Corbi AL, Moro MA, Lizasoain I. Role of TLR4 (Toll-Like Receptor 4) in N1/N2 Neutrophil Programming After Stroke. Stroke 2019; 50(10): 2922-2932. https://www.ncbi.nlm.nih.gov/pubmed/31451099
- Gencer S, van der Vorst EPC, Aslani M, Weber C, Doring Y, Duchene J. Atypical Chemokine Receptors in Cardiovascular Disease. Thromb Haemost 2019; 119(4): 534-541. https://www.ncbi.nlm.nih.gov/pubmed/30716778
- Goldmann L, Duan R, Kragh T, Wittmann G, Weber C, Lorenz R, von Hundelshausen P, Spannagl M, Siess W. Oral Bruton tyrosine kinase inhibitors block activation of the platelet Fc receptor CD32a (FcgammaRIIA): a new option in HIT? Blood Adv 2019; 3(23): 4021-4033. https://www.ncbi.nlm.nih.gov/pubmed/31809536
- Gonzalez-Ramos S, Paz-Garcia M, Rius C, Del Monte-Monge A, Rodriguez C, Fernandez-Garcia V, Andres V, Martinez-Gonzalez J, Lasuncion MA, Martin-Sanz P, Soehnlein O, Bosca L. Endothelial NOD1 directs myeloid cell recruitment in atherosclerosis through VCAM-1. FASEB J 2019; 33(3): 3912-3921. https://www.ncbi.nlm.nih.gov/pubmed/30496704
- Guillamat Prats R, Rami M, Ring L, Rinne P, Lauer E, Lenglet S, Thomas A, Pagano S, Vuilleumier N, Cravatt BF, Weber C, Faussner A, Steffens S. Deficiency of Monoacylglycerol Lipase Enhances IgM Plasma Levels and Limits Atherogenesis in a CB2-Dependent Manner. Thromb Haemost 2019; 119(2): 348-351. https://www.ncbi.nlm.nih.gov/pubmed/30609444
- Guillamat-Prats R, Rami M, Herzig S, Steffens S. Endocannabinoid Signalling in Atherosclerosis and Related Metabolic Complications. Thromb Haemost 2019; 119(4): 567-575. https://www.ncbi.nlm.nih.gov/pubmed/30769363
- Hackler E, 3rd, Lew J, Gore MO, Ayers CR, Atzler D, Khera A, Rohatgi A, Lewis A, Neeland I, Omland T, de Lemos JA. Racial Differences in Cardiovascular Biomarkers in the General Population. J Am Heart Assoc 2019; 8(18): e012729. https://www.ncbi.nlm.nih.gov/pubmed/31514563
- Hidalgo A, Chilvers ER, Summers C, Koenderman L. The Neutrophil Life Cycle. Trends Immunol 2019; 40(7): 584-597. https://www.ncbi.nlm.nih.gov/pubmed/31153737
- Hollander MR, Jansen MF, Hopman L, Dolk E, van de Ven PM, Knaapen P, Horrevoets AJ, Lutgens E, van Royen N. Stimulation of Collateral Vessel Growth by Inhibition of Galectin 2 in Mice Using a Single-Domain Llama-Derived Antibody. J Am Heart Assoc 2019; 8(20): e012806. https://www.ncbi.nlm.nih.gov/pubmed/31594443
- Hu D, Yin C, Luo S, Habenicht AJR, Mohanta SK. Vascular Smooth Muscle Cells Contribute to Atherosclerosis Immunity. Front Immunol 2019; 10: 1101. https://www.ncbi.nlm.nih.gov/pubmed/31164888
- Joppich M, Weber C, Zimmer R. Using Context-Sensitive Text Mining to Identify miRNAs in Different Stages of Atherosclerosis. Thromb Haemost 2019; 119(8): 1247-1264. https://www.ncbi.nlm.nih.gov/pubmed/31378854
- Ketelhuth DFJ, Lutgens E, Back M, Binder CJ, Van den Bossche J, Daniel C, Dumitriu IE, Hoefer I, Libby P, O'Neill L, Weber C, Evans PC. Immunometabolism and atherosclerosis: perspectives and clinical significance: a position paper from the Working Group on Atherosclerosis and Vascular Biology of the European Society of Cardiology. Cardiovasc Res 2019; 115(9): 1385-1392. https://www.ncbi.nlm.nih.gov/pubmed/31228191
- Kiouptsi K, Jackel S, Pontarollo G, Grill A, Kuijpers MJE, Wilms E, Weber C, Sommer F, Nagy M, Neideck C, Jansen Y, Ascher S, Formes H, Karwot C, Bayer F, Kollar B, Subramaniam S, Molitor M, Wenzel P, Rosenstiel P, Todorov H, Gerber S, Walter U, Jurk K, Heemskerk JWM, van der Vorst EPC, Doring Y, Reinhardt C. The Microbiota Promotes Arterial Thrombosis in Low-Density Lipoprotein Receptor-Deficient Mice. mBio 2019; 10(5): e02298-02219. https://www.ncbi.nlm.nih.gov/pubmed/31641089
- Koenen RR. Lysophosphatidylcholine in Platelet Microvesicles: The Grease for Cardiovascular Disease. Thromb Haemost 2019; 119(8): 1202-1204. https://www.ncbi.nlm.nih.gov/pubmed/31266081
- Kornhuber KTI, Seidel H, Pujol C, Meierhofer C, Roschenthaler F, Pressler A, Stockl A, Nagdyman N, Neidenbach RC, von Hundelshausen P, Halle M, Holdenrieder S, Ewert P, Kaemmerer H, Hauser M. Hemostatic abnormalities in adult patients with Marfan syndrome. Cardiovasc Diagn Ther 2019; 9(Suppl 2): S209-S220. https://www.ncbi.nlm.nih.gov/pubmed/31737529
- Lacy M, Atzler D, Liu R, de Winther M, Weber C, Lutgens E. Interactions between dyslipidemia and the immune system and their relevance as putative therapeutic targets in atherosclerosis. Pharmacol Ther 2019; 193: 50-62. https://www.ncbi.nlm.nih.gov/pubmed/30149100
- Leiria LO, Wang CH, Lynes MD, Yang K, Shamsi F, Sato M, Sugimoto S, Chen EY, Bussberg V, Narain NR, Sansbury BE, Darcy J, Huang TL, Kodani SD, Sakaguchi M, Rocha AL, Schulz TJ, Bartelt A, Hotamisligil GS, Hirshman MF, van Leyen K, Goodyear LJ, Bluher M, Cypess AM, Kiebish MA, Spite M, Tseng YH. 12-Lipoxygenase Regulates Cold Adaptation and Glucose Metabolism by Producing the Omega-3 Lipid 12-HEPE from Brown Fat. Cell Metab 2019; 30(4): 768-783 e767. https://www.ncbi.nlm.nih.gov/pubmed/31353262
- Lip GYH, Weber C. Thrombosis and Haemostasis Wishes You a Happy New Year Ahead! Thromb Haemost 2019; 119(1): 1-2. https://www.ncbi.nlm.nih.gov/pubmed/30597493
- Luque-Martin R, Van den Bossche J, Furze RC, Neele AE, van der Velden S, Gijbels MJJ, van Roomen C, Bernard SG, de Jonge WJ, Rioja I, Prinjha RK, Lewis HD, Mander PK, de Winther MPJ. Targeting Histone Deacetylases in Myeloid Cells Inhibits Their Maturation and Inflammatory Function With Limited Effects on Atherosclerosis. Front Pharmacol 2019; 10: 1242. https://www.ncbi.nlm.nih.gov/pubmed/31736752
- Lutgens E. Epigenetic Quenching of VSMC Inflammation in CVD: H3K9me2 in Control. Arterioscler Thromb Vasc Biol 2019; 39(11): 2199-2200. https://www.ncbi.nlm.nih.gov/pubmed/31644350
- Lutgens E, Atzler D, Doring Y, Duchene J, Steffens S, Weber C. Immunotherapy for cardiovascular disease. Eur Heart J 2019; 40(48): 3937-3946. https://www.ncbi.nlm.nih.gov/pubmed/31121017
- Mauler M, Hilgendorf I, Duerschmied D. Response by Mauler et al to Letter Regarding Article, "Platelet Serotonin Aggravates Myocardial Ischemia/Reperfusion Injury via Neutrophil Degranulation". Circulation 2019; 140(7): e292-e293. https://www.ncbi.nlm.nih.gov/pubmed/31403846
- Meeuwsen JAL, de Vries JJ, van Duijvenvoorde A, van der Velden S, van der Laan SW, van Koeverden ID, van de Weg SM, de Borst GJ, de Winther MPJ, Kuiper J, Pasterkamp G, Hoefer IE, de Jager SCA, Queen of Hearts C. Circulating CD14(+)CD16(-) classical monocytes do not associate with a vulnerable plaque phenotype, and do not predict secondary events in severe atherosclerotic patients. J Mol Cell Cardiol 2019; 127: 260-269. https://www.ncbi.nlm.nih.gov/pubmed/30629987
- Nagy M, van Geffen JP, Stegner D, Adams DJ, Braun A, de Witt SM, Elvers M, Geer MJ, Kuijpers MJE, Kunzelmann K, Mori J, Oury C, Pircher J, Pleines I, Poole AW, Senis YA, Verdoold R, Weber C, Nieswandt B, Heemskerk JWM, Baaten C. Comparative Analysis of Microfluidics Thrombus Formation in Multiple Genetically Modified Mice: Link to Thrombosis and Hemostasis. Front Cardiovasc Med 2019; 6: 99. https://www.ncbi.nlm.nih.gov/pubmed/31417909
- Natarelli L, Weber C. Next-Generation Therapeutic Concepts for Atherosclerosis: Focus on Cell Specificity and Noncoding RNAs. Thromb Haemost 2019; 119(8): 1199-1201. https://www.ncbi.nlm.nih.gov/pubmed/31378853
- Neidhart M, Pajak A, Laskari K, Riksen NP, Joosten LAB, Netea MG, Lutgens E, Stroes ESG, Ciurea A, Distler O, Grigorian M, Karouzakis E. Oligomeric S100A4 Is Associated With Monocyte Innate Immune Memory and Bypass of Tolerance to Subsequent Stimulation With Lipopolysaccharides. Front Immunol 2019; 10: 791. https://www.ncbi.nlm.nih.gov/pubmed/31037071
- Ng LG, Ostuni R, Hidalgo A. Heterogeneity of neutrophils. Nat Rev Immunol 2019; 19(4): 255-265. https://www.ncbi.nlm.nih.gov/pubmed/30816340
- Nicorescu I, Dallinga GM, de Winther MPJ, Stroes ESG, Bahjat M. Potential epigenetic therapeutics for atherosclerosis treatment. Atherosclerosis 2019; 281: 189-197. https://www.ncbi.nlm.nih.gov/pubmed/30340764
- Nitz K, Lacy M, Atzler D. Amino Acids and Their Metabolism in Atherosclerosis. Arterioscler Thromb Vasc Biol 2019; 39(3): 319-330. https://www.ncbi.nlm.nih.gov/pubmed/30650999
- Noels H, Weber C, Koenen RR. Chemokines as Therapeutic Targets in Cardiovascular Disease. Arterioscler Thromb Vasc Biol 2019; 39(4): 583-592. https://www.ncbi.nlm.nih.gov/pubmed/30760014
- Onat UI, Yildirim AD, Tufanli O, Cimen I, Kocaturk B, Veli Z, Hamid SM, Shimada K, Chen S, Sin J, Shah PK, Gottlieb RA, Arditi M, Erbay E. Intercepting the Lipid-Induced Integrated Stress Response Reduces Atherosclerosis. J Am Coll Cardiol 2019; 73(10): 1149-1169. https://www.ncbi.nlm.nih.gov/pubmed/30871699
- Paloschi V, Winter H, Viola J, Soehnlein O, Maegdefessel L. Mechanistic Links between Non-Coding RNAs and Myeloid Cell Inflammation in Atherosclerosis. Thromb Haemost 2019; 119(8): 1205-1211. https://www.ncbi.nlm.nih.gov/pubmed/31035303
- Pfeiler S, Thakur M, Grunauer P, Megens RTA, Joshi U, Coletti R, Samara V, Muller-Stoy G, Ishikawa-Ankerhold H, Stark K, Klingl A, Frohlich T, Arnold GJ, Wormann S, Bruns CJ, Algul H, Weber C, Massberg S, Engelmann B. CD36-triggered cell invasion and persistent tissue colonization by tumor microvesicles during metastasis. FASEB J 2019; 33(2): 1860-1872. https://www.ncbi.nlm.nih.gov/pubmed/30207797
- Pfeiler S, Winkels H, Kelm M, Gerdes N. IL-1 family cytokines in cardiovascular disease. Cytokine 2019; 122: 154215. https://www.ncbi.nlm.nih.gov/pubmed/29198612
- Puhl SL, Steffens S. Neutrophils in Post-myocardial Infarction Inflammation: Damage vs. Resolution? Front Cardiovasc Med 2019; 6: 25. https://www.ncbi.nlm.nih.gov/pubmed/30937305
- Puhl SL, Weeks KL, Guran A, Ranieri A, Boknik P, Kirchhefer U, Muller FU, Avkiran M. Role of type 2A phosphatase regulatory subunit B56alpha in regulating cardiac responses to beta-adrenergic stimulation in vivo. Cardiovasc Res 2019; 115(3): 519-529. https://www.ncbi.nlm.nih.gov/pubmed/30203051
- Rasmuson J, Kenne E, Wahlgren M, Soehnlein O, Lindbom L. Heparinoid sevuparin inhibits Streptococcus-induced vascular leak through neutralizing neutrophil-derived proteins. FASEB J 2019; 33(9): 10443-10452. https://www.ncbi.nlm.nih.gov/pubmed/31216421
- Reiche ME, den Toom M, Willemsen L, van Os B, Gijbels MJJ, Gerdes N, Aarts S, Lutgens E. Deficiency of T cell CD40L has minor beneficial effects on obesity-induced metabolic dysfunction. BMJ Open Diabetes Res Care 2019; 7(1): e000829. https://www.ncbi.nlm.nih.gov/pubmed/31908798
- Sager HB, Husser O, Steffens S, Laugwitz KL, Schunkert H, Kastrati A, Ndrepepa G, Kessler T. Time-of-day at symptom onset was not associated with infarct size and long-term prognosis in patients with ST-segment elevation myocardial infarction. J Transl Med 2019; 17(1): 180. https://www.ncbi.nlm.nih.gov/pubmed/31142323
- Schloss MJ, Horckmans M, Guillamat-Prats R, Hering D, Lauer E, Lenglet S, Weber C, Thomas A, Steffens S. 2-Arachidonoylglycerol mobilizes myeloid cells and worsens heart function after acute myocardial infarction. Cardiovasc Res 2019; 115(3): 602-613. https://www.ncbi.nlm.nih.gov/pubmed/30295758
- Seijkens TTP, Poels K, Meiler S, van Tiel CM, Kusters PJH, Reiche M, Atzler D, Winkels H, Tjwa M, Poelman H, Slutter B, Kuiper J, Gijbels M, Kuivenhoven JA, Matic LP, Paulsson-Berne G, Hedin U, Hansson GK, Nicolaes GAF, Daemen M, Weber C, Gerdes N, de Winther MPJ, Lutgens E. Deficiency of the T cell regulator Casitas B-cell lymphoma-B aggravates atherosclerosis by inducing CD8+ T cell-mediated macrophage death. Eur Heart J 2019; 40(4): 372-382. https://www.ncbi.nlm.nih.gov/pubmed/30452556
- Silvestre-Roig C, Braster Q, Wichapong K, Lee EY, Teulon JM, Berrebeh N, Winter J, Adrover JM, Santos GS, Froese A, Lemnitzer P, Ortega-Gomez A, Chevre R, Marschner J, Schumski A, Winter C, Perez-Olivares L, Pan C, Paulin N, Schoufour T, Hartwig H, Gonzalez-Ramos S, Kamp F, Megens RTA, Mowen KA, Gunzer M, Maegdefessel L, Hackeng T, Lutgens E, Daemen M, von Blume J, Anders HJ, Nikolaev VO, Pellequer JL, Weber C, Hidalgo A, Nicolaes GAF, Wong GCL, Soehnlein O. Externalized histone H4 orchestrates chronic inflammation by inducing lytic cell death. Nature 2019; 569(7755): 236-240. https://www.ncbi.nlm.nih.gov/pubmed/31043745
- Silvestre-Roig C, Fridlender ZG, Glogauer M, Scapini P. Neutrophil Diversity in Health and Disease. Trends Immunol 2019; 40(7): 565-583. https://www.ncbi.nlm.nih.gov/pubmed/31160207
- Soehnlein O. Neutrophil Research, Quo Vadis? Trends Immunol 2019; 40(7): 561-564. https://www.ncbi.nlm.nih.gov/pubmed/31133465
- Steffens S, Weber C. Immunotherapy for Atherosclerosis-Novel Concepts. Thromb Haemost 2019; 119(4): 515-516. https://www.ncbi.nlm.nih.gov/pubmed/30887489
- Teixido J, Hidalgo A, Fagerholm S. Editorial: Leukocyte Trafficking in Homeostasis and Disease. Front Immunol 2019; 10: 2560. https://www.ncbi.nlm.nih.gov/pubmed/31736975
- Thiem K, Hoeke G, van den Berg S, Hijmans A, Jacobs CWM, Zhou E, Mol IM, Mouktaroudi M, Bussink J, Kanneganti TD, Lutgens E, Stienstra R, Tack CJ, Netea MG, Rensen PCN, Berbee JFP, van Diepen JA. Deletion of hematopoietic Dectin-2 or CARD9 does not protect against atherosclerotic plaque formation in hyperlipidemic mice. Sci Rep 2019; 9(1): 4337. https://www.ncbi.nlm.nih.gov/pubmed/30867470
- Tunon J, Badimon L, Bochaton-Piallat ML, Cariou B, Daemen MJ, Egido J, Evans PC, Hoefer IE, Ketelhuth DFJ, Lutgens E, Matter CM, Monaco C, Steffens S, Stroes E, Vindis C, Weber C, Back M. Identifying the anti-inflammatory response to lipid lowering therapy: a position paper from the working group on atherosclerosis and vascular biology of the European Society of Cardiology. Cardiovasc Res 2019; 115(1): 10-19. https://www.ncbi.nlm.nih.gov/pubmed/30534957
- Van Avondt K, Maegdefessel L, Soehnlein O. Therapeutic Targeting of Neutrophil Extracellular Traps in Atherogenic Inflammation. Thromb Haemost 2019; 119(4): 542-552. https://www.ncbi.nlm.nih.gov/pubmed/30731493
- Van Avondt K, Nur E, Zeerleder S. Mechanisms of haemolysis-induced kidney injury. Nat Rev Nephrol 2019; 15(11): 671-692. https://www.ncbi.nlm.nih.gov/pubmed/31455889
- van Beek AA, Van den Bossche J, Mastroberardino PG, de Winther MPJ, Leenen PJM. Metabolic Alterations in Aging Macrophages: Ingredients for Inflammaging? Trends Immunol 2019; 40(2): 113-127. https://www.ncbi.nlm.nih.gov/pubmed/30626541
- van der Vorst EPC, Donners M. ADAM8 in the cardiovascular system: An innocent bystander with clinical use? Atherosclerosis 2019; 286: 147-149. https://www.ncbi.nlm.nih.gov/pubmed/31003630
- van der Vorst EPC, Mandl M, Muller M, Neideck C, Jansen Y, Hristov M, Gencer S, Peters LJF, Meiler S, Feld M, Geiselhoringer AL, de Jong RJ, Ohnmacht C, Noels H, Soehnlein O, Drechsler M, Weber C, Doring Y. Hematopoietic ChemR23 (Chemerin Receptor 23) Fuels Atherosclerosis by Sustaining an M1 Macrophage-Phenotype and Guidance of Plasmacytoid Dendritic Cells to Murine Lesions-Brief Report. Arterioscler Thromb Vasc Biol 2019; 39(4): 685-693. https://www.ncbi.nlm.nih.gov/pubmed/30786742
- van der Vorst EPC, Peters LJF, Muller M, Gencer S, Yan Y, Weber C, Doring Y. G-Protein Coupled Receptor Targeting on Myeloid Cells in Atherosclerosis. Front Pharmacol 2019; 10: 531. https://www.ncbi.nlm.nih.gov/pubmed/31191301
- van der Vorst EPC, Weber C. Novel Features of Monocytes and Macrophages in Cardiovascular Biology and Disease. Arterioscler Thromb Vasc Biol 2019; 39(2): e30-e37. https://www.ncbi.nlm.nih.gov/pubmed/30673349
- Varasteh Z, Mohanta S, Li Y, Lopez Armbruster N, Braeuer M, Nekolla SG, Habenicht A, Sager HB, Raes G, Weber W, Hernot S, Schwaiger M. Targeting mannose receptor expression on macrophages in atherosclerotic plaques of apolipoprotein E-knockout mice using (68)Ga-NOTA-anti-MMR nanobody: non-invasive imaging of atherosclerotic plaques. EJNMMI Res 2019; 9(1): 5. https://www.ncbi.nlm.nih.gov/pubmed/30666513
- Varasteh Z, Mohanta S, Robu S, Braeuer M, Li Y, Omidvari N, Topping G, Sun T, Nekolla SG, Richter A, Weber C, Habenicht A, Haberkorn UA, Weber WA. Molecular Imaging of Fibroblast Activity After Myocardial Infarction Using a (68)Ga-Labeled Fibroblast Activation Protein Inhibitor, FAPI-04. J Nucl Med 2019; 60(12): 1743-1749. https://www.ncbi.nlm.nih.gov/pubmed/31405922
- Vila-Caballer M, Gonzalez-Granado JM, Zorita V, Abu Nabah YN, Silvestre-Roig C, Del Monte-Monge A, Molina-Sanchez P, Ait-Oufella H, Andres-Manzano MJ, Sanz MJ, Weber C, Kremer L, Gutierrez J, Mallat Z, Andres V. Disruption of the CCL1-CCR8 axis inhibits vascular Treg recruitment and function and promotes atherosclerosis in mice. J Mol Cell Cardiol 2019; 132: 154-163. https://www.ncbi.nlm.nih.gov/pubmed/31121182
- Weber C, Lip GYH. Thrombosis and Haemostasis 2018 Editor's Choice Papers. Thromb Haemost 2019; 119(1): 183-186. https://www.ncbi.nlm.nih.gov/pubmed/30597513
- Welz PS, Zinna VM, Symeonidi A, Koronowski KB, Kinouchi K, Smith JG, Guillen IM, Castellanos A, Furrow S, Aragon F, Crainiciuc G, Prats N, Caballero JM, Hidalgo A, Sassone-Corsi P, Benitah SA. BMAL1-Driven Tissue Clocks Respond Independently to Light to Maintain Homeostasis. Cell 2019; 177(6): 1436-1447 e1412. https://www.ncbi.nlm.nih.gov/pubmed/31150620
- Wenstedt EF, Verberk SG, Kroon J, Neele AE, Baardman J, Claessen N, Pasaoglu OT, Rademaker E, Schrooten EM, Wouda RD, de Winther MP, Aten J, Vogt L, Van den Bossche J. Salt increases monocyte CCR2 expression and inflammatory responses in humans. JCI Insight 2019; 4(21): e130508. https://www.ncbi.nlm.nih.gov/pubmed/31672939
- Wichapong K, Poelman H, Ercig B, Hrdinova J, Liu X, Lutgens E, Nicolaes GA. Rational modulator design by exploitation of protein-protein complex structures. Future Med Chem 2019; 11(9): 1015-1033. https://www.ncbi.nlm.nih.gov/pubmed/31141413
- Willemsen L, Neele AE, van der Velden S, Prange KHM, den Toom M, van Roomen C, Reiche ME, Griffith GR, Gijbels MJJ, Lutgens E, de Winther MPJ. Peritoneal macrophages have an impaired immune response in obesity which can be reversed by subsequent weight loss. BMJ Open Diabetes Res Care 2019; 7(1): e000751. https://www.ncbi.nlm.nih.gov/pubmed/31798899
- Worthmann A, Schlein C, Berbee JFP, Rensen PCN, Heeren J, Bartelt A. Effects of Pharmacological Thermogenic Adipocyte Activation on Metabolism and Atherosclerotic Plaque Regression. Nutrients 2019; 11(2): 463. https://www.ncbi.nlm.nih.gov/pubmed/30813320
- Yin C, Ackermann S, Ma Z, Mohanta SK, Zhang C, Li Y, Nietzsche S, Westermann M, Peng L, Hu D, Bontha SV, Srikakulapu P, Beer M, Megens RTA, Steffens S, Hildner M, Halder LD, Eckstein HH, Pelisek J, Herms J, Roeber S, Arzberger T, Borodovsky A, Habenicht L, Binder CJ, Weber C, Zipfel PF, Skerka C, Habenicht AJR. ApoE attenuates unresolvable inflammation by complex formation with activated C1q. Nat Med 2019; 25(3): 496-506. https://www.ncbi.nlm.nih.gov/pubmed/30692699
- Aarts S, Reiche ME, den Toom M, Beckers L, Gijbels MJJ, Gerdes N, de Winther MPJ, Lutgens E. Macrophage CD40 plays a minor role in obesity-induced metabolic dysfunction. PLoS One 2018; 13(8): e0202150. https://www.ncbi.nlm.nih.gov/pubmed/30096208
- Ameti R, Melgrati S, Radice E, Cameroni E, Hub E, Thelen S, Rot A, Thelen M. Characterization of a chimeric chemokine as a specific ligand for ACKR3. J Leukoc Biol 2018; 104(2): 391-400. https://www.ncbi.nlm.nih.gov/pubmed/29601107
- Atzler D, de Winther MPJ. DARC matter(s) for inflammatory cells. Cardiovasc Res 2018; 114(2): e11-e13. https://www.ncbi.nlm.nih.gov/pubmed/29373721
- Baardman J, Verberk SGS, Prange KHM, van Weeghel M, van der Velden S, Ryan DG, Wust RCI, Neele AE, Speijer D, Denis SW, Witte ME, Houtkooper RH, O'Neill L A, Knatko EV, Dinkova-Kostova AT, Lutgens E, de Winther MPJ, Van den Bossche J. A Defective Pentose Phosphate Pathway Reduces Inflammatory Macrophage Responses during Hypercholesterolemia. Cell Rep 2018; 25(8): 2044-2052 e2045. https://www.ncbi.nlm.nih.gov/pubmed/30463003
- Baaten C, Meacham S, de Witt SM, Feijge MAH, Adams DJ, Akkerman JN, Cosemans J, Grassi L, Jupe S, Kostadima M, Mattheij NJA, Prins MH, Ramirez-Solis R, Soehnlein O, Swieringa F, Weber C, White JK, Ouwehand WH, Heemskerk JWM. A synthesis approach of mouse studies to identify genes and proteins in arterial thrombosis and bleeding. Blood 2018; 132(24): e35-e46. https://www.ncbi.nlm.nih.gov/pubmed/30275110
- Bahls M, Atzler D, Markus MRP, Friedrich N, Boger RH, Volzke H, Felix SB, Schwedhelm E, Dorr M. Low-Circulating Homoarginine is Associated with Dilatation and Decreased Function of the Left Ventricle in the General Population. Biomolecules 2018; 8(3): 63. https://www.ncbi.nlm.nih.gov/pubmed/30061520
- Baldassarri F, Schwedhelm E, Atzler D, Boger RH, Cordts K, Haller B, Pressler A, Muller S, Suchy C, Wachter R, Dungen HD, Hasenfuss G, Pieske B, Halle M, Edelmann F, Duvinage A. Relationship between exercise intervention and NO pathway in patients with heart failure with preserved ejection fraction. Biomarkers 2018; 23(6): 540-550. https://www.ncbi.nlm.nih.gov/pubmed/29619838
- Braza MS, van Leent MMT, Lameijer M, Sanchez-Gaytan BL, Arts RJW, Perez-Medina C, Conde P, Garcia MR, Gonzalez-Perez M, Brahmachary M, Fay F, Kluza E, Kossatz S, Dress RJ, Salem F, Rialdi A, Reiner T, Boros P, Strijkers GJ, Calcagno CC, Ginhoux F, Marazzi I, Lutgens E, Nicolaes GAF, Weber C, Swirski FK, Nahrendorf M, Fisher EA, Duivenvoorden R, Fayad ZA, Netea MG, Mulder WJM, Ochando J. Inhibiting Inflammation with Myeloid Cell-Specific Nanobiologics Promotes Organ Transplant Acceptance. Immunity 2018; 49(5): 819-828 e816. https://www.ncbi.nlm.nih.gov/pubmed/30413362
- Busygina K, Jamasbi J, Seiler T, Deckmyn H, Weber C, Brandl R, Lorenz R, Siess W. Oral Bruton tyrosine kinase inhibitors selectively block atherosclerotic plaque-triggered thrombus formation in humans. Blood 2018; 131(24): 2605-2616. https://www.ncbi.nlm.nih.gov/pubmed/29559479
- Caporali A, Back M, Daemen MJ, Hoefer IE, Jones EA, Lutgens E, Matter CM, Bochaton-Piallat ML, Siekmann AF, Sluimer JC, Steffens S, Tunon J, Vindis C, Wentzel JJ, Yla-Herttuala S, Evans PC. Future directions for therapeutic strategies in post-ischaemic vascularization: a position paper from European Society of Cardiology Working Group on Atherosclerosis and Vascular Biology. Cardiovasc Res 2018; 114(11): 1411-1421. https://www.ncbi.nlm.nih.gov/pubmed/30016405
- Casanova-Acebes M, Nicolas-Avila JA, Li JL, Garcia-Silva S, Balachander A, Rubio-Ponce A, Weiss LA, Adrover JM, Burrows K, N AG, Ballesteros I, Devi S, Quintana JA, Crainiciuc G, Leiva M, Gunzer M, Weber C, Nagasawa T, Soehnlein O, Merad M, Mortha A, Ng LG, Peinado H, Hidalgo A. Neutrophils instruct homeostatic and pathological states in naive tissues. J Exp Med 2018; 215(11): 2778-2795. https://www.ncbi.nlm.nih.gov/pubmed/30282719
- Chevre R, Silvestre-Roig C, Soehnlein O. Nutritional Modulation of Innate Immunity: The Fat-Bile-Gut Connection. Trends Endocrinol Metab 2018; 29(10): 686-698. https://www.ncbi.nlm.nih.gov/pubmed/30197155
- Curaj A, Wu Z, Rix A, Gresch O, Sternkopf M, Alampour-Rajabi S, Lammers T, van Zandvoort M, Weber C, Koenen RR, Liehn EA, Kiessling F. Molecular Ultrasound Imaging of Junctional Adhesion Molecule A Depicts Acute Alterations in Blood Flow and Early Endothelial Dysregulation. Arterioscler Thromb Vasc Biol 2018; 38(1): 40-48. https://www.ncbi.nlm.nih.gov/pubmed/29191926
- Daugherty A, Lu HS, Hegele RA, Mackman N, Rader DJ, Schmidt AM, Weber C. Response by Daugherty et al to Letter Regarding Article, "Consideration of Sex Differences in Design and Reporting of Experimental Arterial Pathology Studies: A Statement From the Arteriosclerosis, Thrombosis, and Vascular Biology Council". Arterioscler Thromb Vasc Biol 2018; 38(6): e101-e102. https://www.ncbi.nlm.nih.gov/pubmed/29793996
- den Harder AM, de Jong PA, de Groot MCH, Wolterink JM, Budde RPJ, Isgum I, van Solinge WW, Ten Berg MJ, Lutgens E, Veldhuis WB, Haitjema S, Hoefer IE, Leiner T. Commonly available hematological biomarkers are associated with the extent of coronary calcifications. Atherosclerosis 2018; 275: 166-173. https://www.ncbi.nlm.nih.gov/pubmed/29920437
- Di Francesco A, Fedrigo M, Santovito D, Natarelli L, Castellani C, De Pascale F, Toscano G, Fraiese A, Feltrin G, Benazzi E, Nocco A, Thiene G, Valente M, Valle G, Schober A, Gerosa G, Angelini A. MicroRNA signatures in cardiac biopsies and detection of allograft rejection. J Heart Lung Transplant 2018; 37(11): 1329-1340. https://www.ncbi.nlm.nih.gov/pubmed/30174164
- Dickhout A, Koenen RR. Extracellular Vesicles as Biomarkers in Cardiovascular Disease; Chances and Risks. Front Cardiovasc Med 2018; 5: 113. https://www.ncbi.nlm.nih.gov/pubmed/30186839
- Domschke G, Linden F, Pawig L, Hafner A, Akhavanpoor M, Reymann J, Doesch AO, Erbel C, Weber C, Katus HA, Noels H, Erfle H, Gleissner CA, Runz H. Systematic RNA-interference in primary human monocyte-derived macrophages: A high-throughput platform to study foam cell formation. Sci Rep 2018; 8(1): 10516. https://www.ncbi.nlm.nih.gov/pubmed/30002403
- Doring Y, van der Vorst EPC. Gouty Offense in Patients With Obstructive Coronary Artery Disease Despite State-of-the-Art Therapy. J Am Heart Assoc 2018; 7(16): e010322. https://www.ncbi.nlm.nih.gov/pubmed/30369331
- Dorn T, Kornherr J, Parrotta EI, Zawada D, Ayetey H, Santamaria G, Iop L, Mastantuono E, Sinnecker D, Goedel A, Dirschinger RJ, My I, Laue S, Bozoglu T, Baarlink C, Ziegler T, Graf E, Hinkel R, Cuda G, Kaab S, Grace AA, Grosse R, Kupatt C, Meitinger T, Smith AG, Laugwitz KL, Moretti A. Interplay of cell-cell contacts and RhoA/MRTF-A signaling regulates cardiomyocyte identity. EMBO J 2018; 37(12): e98133. https://www.ncbi.nlm.nih.gov/pubmed/29764980
- Eikendal ALM, Bots ML, Gohar A, Lutgens E, Hoefer IE, den Ruijter HM, Leiner T. Circulating levels of P-selectin and E-selectin relate to cardiovascular magnetic resonance-derived aortic characteristics in young adults from the general population, a cross-sectional study. J Cardiovasc Magn Reson 2018; 20(1): 54. https://www.ncbi.nlm.nih.gov/pubmed/30068374
- Evrard M, Kwok IWH, Chong SZ, Teng KWW, Becht E, Chen J, Sieow JL, Penny HL, Ching GC, Devi S, Adrover JM, Li JLY, Liong KH, Tan L, Poon Z, Foo S, Chua JW, Su IH, Balabanian K, Bachelerie F, Biswas SK, Larbi A, Hwang WYK, Madan V, Koeffler HP, Wong SC, Newell EW, Hidalgo A, Ginhoux F, Ng LG. Developmental Analysis of Bone Marrow Neutrophils Reveals Populations Specialized in Expansion, Trafficking, and Effector Functions. Immunity 2018; 48(2): 364-379 e368. https://www.ncbi.nlm.nih.gov/pubmed/29466759
- Faller KME, Atzler D, McAndrew DJ, Zervou S, Whittington HJ, Simon JN, Aksentijevic D, Ten Hove M, Choe CU, Isbrandt D, Casadei B, Schneider JE, Neubauer S, Lygate CA. Impaired cardiac contractile function in arginine:glycine amidinotransferase knockout mice devoid of creatine is rescued by homoarginine but not creatine. Cardiovasc Res 2018; 114(3): 417-430. https://www.ncbi.nlm.nih.gov/pubmed/29236952
- Girbl T, Lenn T, Perez L, Rolas L, Barkaway A, Thiriot A, Del Fresno C, Lynam E, Hub E, Thelen M, Graham G, Alon R, Sancho D, von Andrian UH, Voisin MB, Rot A, Nourshargh S. Distinct Compartmentalization of the Chemokines CXCL1 and CXCL2 and the Atypical Receptor ACKR1 Determine Discrete Stages of Neutrophil Diapedesis. Immunity 2018; 49(6): 1062-1076 e1066. https://www.ncbi.nlm.nih.gov/pubmed/30446388
- Gomez-Moreno D, Adrover JM, Hidalgo A. Neutrophils as effectors of vascular inflammation. Eur J Clin Invest 2018; 48 Suppl 2(S2): e12940. https://www.ncbi.nlm.nih.gov/pubmed/29682731
- Hinkel R, Klett K, Bahr A, Kupatt C. Thymosin beta4-mediated protective effects in the heart. Expert Opin Biol Ther 2018; 18(sup1): 121-129. https://www.ncbi.nlm.nih.gov/pubmed/30063857
- Hoogeveen RM, Nahrendorf M, Riksen NP, Netea MG, de Winther MPJ, Lutgens E, Nordestgaard BG, Neidhart M, Stroes ESG, Catapano AL, Bekkering S. Monocyte and haematopoietic progenitor reprogramming as common mechanism underlying chronic inflammatory and cardiovascular diseases. Eur Heart J 2018; 39(38): 3521-3527. https://www.ncbi.nlm.nih.gov/pubmed/29069365
- Horckmans M, Bianchini M, Santovito D, Megens RTA, Springael JY, Negri I, Vacca M, Di Eusanio M, Moschetta A, Weber C, Duchene J, Steffens S. Pericardial Adipose Tissue Regulates Granulopoiesis, Fibrosis, and Cardiac Function After Myocardial Infarction. Circulation 2018; 137(9): 948-960. https://www.ncbi.nlm.nih.gov/pubmed/29167227
- Jagschies L, Hirschvogel M, Matallo J, Maier A, Mild K, Brunner H, Hinkel R, Gee MW, Radermacher P, Wildhirt SM, Hafner S. Individualized Biventricular Epicardial Augmentation Technology in a Drug-Induced Porcine Failing Heart Model. ASAIO J 2018; 64(4): 480-488. https://www.ncbi.nlm.nih.gov/pubmed/29028694
- Kuipers EN, Kantae V, Maarse BCE, van den Berg SM, van Eenige R, Nahon KJ, Reifel-Miller A, Coskun T, de Winther MPJ, Lutgens E, Kooijman S, Harms AC, Hankemeier T, van der Stelt M, Rensen PCN, Boon MR. High Fat Diet Increases Circulating Endocannabinoids Accompanied by Increased Synthesis Enzymes in Adipose Tissue. Front Physiol 2018; 9: 1913. https://www.ncbi.nlm.nih.gov/pubmed/30687125
- Kusters PJH, Lutgens E, Seijkens TTP. Exploring immune checkpoints as potential therapeutic targets in atherosclerosis. Cardiovasc Res 2018; 114(3): 368-377. https://www.ncbi.nlm.nih.gov/pubmed/29309533
- Lameijer M, Binderup T, van Leent MMT, Senders ML, Fay F, Malkus J, Sanchez-Gaytan BL, Teunissen AJP, Karakatsanis N, Robson P, Zhou X, Ye Y, Wojtkiewicz G, Tang J, Seijkens TTP, Kroon J, Stroes ESG, Kjaer A, Ochando J, Reiner T, Perez-Medina C, Calcagno C, Fisher EA, Zhang B, Temel RE, Swirski FK, Nahrendorf M, Fayad ZA, Lutgens E, Mulder WJM, Duivenvoorden R. Efficacy and safety assessment of a TRAF6-targeted nanoimmunotherapy in atherosclerotic mice and non-human primates. Nat Biomed Eng 2018; 2(5): 279-292. https://www.ncbi.nlm.nih.gov/pubmed/30936448
- Langin M, Mayr T, Reichart B, Michel S, Buchholz S, Guethoff S, Dashkevich A, Baehr A, Egerer S, Bauer A, Mihalj M, Panelli A, Issl L, Ying J, Fresch AK, Buttgereit I, Mokelke M, Radan J, Werner F, Lutzmann I, Steen S, Sjoberg T, Paskevicius A, Qiuming L, Sfriso R, Rieben R, Dahlhoff M, Kessler B, Kemter E, Kurome M, Zakhartchenko V, Klett K, Hinkel R, Kupatt C, Falkenau A, Reu S, Ellgass R, Herzog R, Binder U, Wich G, Skerra A, Ayares D, Kind A, Schonmann U, Kaup FJ, Hagl C, Wolf E, Klymiuk N, Brenner P, Abicht JM. Consistent success in life-supporting porcine cardiac xenotransplantation. Nature 2018; 564(7736): 430-433. https://www.ncbi.nlm.nih.gov/pubmed/30518863
- Leoni G, Soehnlein O. (Re) Solving Repair After Myocardial Infarction. Front Pharmacol 2018; 9: 1342. https://www.ncbi.nlm.nih.gov/pubmed/30534069
- Lu HS, Schmidt AM, Hegele RA, Mackman N, Rader DJ, Weber C, Daugherty A. Reporting Sex and Sex Differences in Preclinical Studies. Arterioscler Thromb Vasc Biol 2018; 38(10): e171-e184. https://www.ncbi.nlm.nih.gov/pubmed/30354222
- Maas SL, Soehnlein O, Viola JR. Organ-Specific Mechanisms of Transendothelial Neutrophil Migration in the Lung, Liver, Kidney, and Aorta. Front Immunol 2018; 9: 2739. https://www.ncbi.nlm.nih.gov/pubmed/30538702
- Mederos YSM, Gudermann T, Storch U. Emerging Roles of Diacylglycerol-Sensitive TRPC4/5 Channels. Cells 2018; 7(11): 218. https://www.ncbi.nlm.nih.gov/pubmed/30463370
- Natarelli L, Geissler C, Csaba G, Wei Y, Zhu M, di Francesco A, Hartmann P, Zimmer R, Schober A. miR-103 promotes endothelial maladaptation by targeting lncWDR59. Nat Commun 2018; 9(1): 2645. https://www.ncbi.nlm.nih.gov/pubmed/29980665
- Neele AE, de Winther MPJ. Repressing the repressor: Ezh2 mediates macrophage activation. J Exp Med 2018; 215(5): 1269-1271. https://www.ncbi.nlm.nih.gov/pubmed/29691302
- Neele AE, Gijbels MJJ, van der Velden S, Hoeksema MA, Boshuizen MCS, Prange KHM, Chen HJ, Van den Bossche J, van Roomen C, Shami A, Levels JHM, Kroon J, Lucas T, Dimmeler S, Lutgens E, de Winther MPJ. Myeloid Kdm6b deficiency results in advanced atherosclerosis. Atherosclerosis 2018; 275: 156-165. https://www.ncbi.nlm.nih.gov/pubmed/29908485
- Nicolas-Avila JA, Hidalgo A, Ballesteros I. Specialized functions of resident macrophages in brain and heart. J Leukoc Biol 2018; 104(4): 743-756. https://www.ncbi.nlm.nih.gov/pubmed/29947422
- Niekamp C, Atzler D, Ojeda FM, Sinning CR, Lackner KJ, Boger RH, Munzel T, Beutel ME, Schmidtmann I, Pfeiffer N, Leuschner A, Blankenberg S, Wild PS, Zeller T, Schwedhelm E, Schnabel RB. Cross-Sectional Associations between Homoarginine, Intermediate Phenotypes, and Atrial Fibrillation in the Community-The Gutenberg Health Study. Biomolecules 2018; 8(3): 86. https://www.ncbi.nlm.nih.gov/pubmed/30200232
- Pacher P, Steffens S, Hasko G, Schindler TH, Kunos G. Cardiovascular effects of marijuana and synthetic cannabinoids: the good, the bad, and the ugly. Nat Rev Cardiol 2018; 15(3): 151-166. https://www.ncbi.nlm.nih.gov/pubmed/28905873
- Patel J, Lutgens E. Scientists on the Spot: Esther Lutgens on the immune system and atherosclerosis. Cardiovasc Res 2018; 114(14): e113. https://www.ncbi.nlm.nih.gov/pubmed/30476016
- Paulin N, Viola JR, Maas SL, de Jong R, Fernandes-Alnemri T, Weber C, Drechsler M, Doring Y, Soehnlein O. Double-Strand DNA Sensing Aim2 Inflammasome Regulates Atherosclerotic Plaque Vulnerability. Circulation 2018; 138(3): 321-323. https://www.ncbi.nlm.nih.gov/pubmed/30012706
- Pfeiler S, Gerdes N. Atherosclerosis: cell biology and lipoproteins - focus on anti-inflammatory therapies. Curr Opin Lipidol 2018; 29(1): 53-55. https://www.ncbi.nlm.nih.gov/pubmed/29298275
- Pircher J, Czermak T, Ehrlich A, Eberle C, Gaitzsch E, Margraf A, Grommes J, Saha P, Titova A, Ishikawa-Ankerhold H, Stark K, Petzold T, Stocker T, Weckbach LT, Novotny J, Sperandio M, Nieswandt B, Smith A, Mannell H, Walzog B, Horst D, Soehnlein O, Massberg S, Schulz C. Cathelicidins prime platelets to mediate arterial thrombosis and tissue inflammation. Nat Commun 2018; 9(1): 1523. https://www.ncbi.nlm.nih.gov/pubmed/29670076
- Poller W, Dimmeler S, Heymans S, Zeller T, Haas J, Karakas M, Leistner DM, Jakob P, Nakagawa S, Blankenberg S, Engelhardt S, Thum T, Weber C, Meder B, Hajjar R, Landmesser U. Non-coding RNAs in cardiovascular diseases: diagnostic and therapeutic perspectives. Eur Heart J 2018; 39(29): 2704-2716. https://www.ncbi.nlm.nih.gov/pubmed/28430919
- Rami M, Guillamat-Prats R, Rinne P, Salvermoser M, Ring L, Bianchini M, Blanchet X, Megens RTA, Doring Y, Walzog B, Soehnlein O, Weber C, Faussner A, Steffens S. Chronic Intake of the Selective Serotonin Reuptake Inhibitor Fluoxetine Enhances Atherosclerosis. Arterioscler Thromb Vasc Biol 2018; 38(5): 1007-1019. https://www.ncbi.nlm.nih.gov/pubmed/29567680
- Renz BW, Takahashi R, Tanaka T, Macchini M, Hayakawa Y, Dantes Z, Maurer HC, Chen X, Jiang Z, Westphalen CB, Ilmer M, Valenti G, Mohanta SK, Habenicht AJR, Middelhoff M, Chu T, Nagar K, Tailor Y, Casadei R, Di Marco M, Kleespies A, Friedman RA, Remotti H, Reichert M, Worthley DL, Neumann J, Werner J, Iuga AC, Olive KP, Wang TC. beta2 Adrenergic-Neurotrophin Feedforward Loop Promotes Pancreatic Cancer. Cancer Cell 2018; 33(1): 75-90 e77. https://www.ncbi.nlm.nih.gov/pubmed/29249692
- Rinne P, Guillamat-Prats R, Rami M, Bindila L, Ring L, Lyytikainen LP, Raitoharju E, Oksala N, Lehtimaki T, Weber C, van der Vorst EPC, Steffens S. Palmitoylethanolamide Promotes a Proresolving Macrophage Phenotype and Attenuates Atherosclerotic Plaque Formation. Arterioscler Thromb Vasc Biol 2018; 38(11): 2562-2575. https://www.ncbi.nlm.nih.gov/pubmed/30354245
- Rinne P, Kadiri JJ, Velasco-Delgado M, Nuutinen S, Viitala M, Hollmen M, Rami M, Savontaus E, Steffens S. Melanocortin 1 Receptor Deficiency Promotes Atherosclerosis in Apolipoprotein E(-/-) Mice. Arterioscler Thromb Vasc Biol 2018; 38(2): 313-323. https://www.ncbi.nlm.nih.gov/pubmed/29284608
- Rouwet E, Lutgens E. 2016 Jeffrey M. Hoeg Award Lecture. Arterioscler Thromb Vasc Biol 2018; 38(8): 1678-1688. https://www.ncbi.nlm.nih.gov/pubmed/29930003
- Salas-Perdomo A, Miro-Mur F, Urra X, Justicia C, Gallizioli M, Zhao Y, Brait VH, Laredo C, Tudela R, Hidalgo A, Chamorro A, Planas AM. T Cells Prevent Hemorrhagic Transformation in Ischemic Stroke by P-Selectin Binding. Arterioscler Thromb Vasc Biol 2018; 38(8): 1761-1771. https://www.ncbi.nlm.nih.gov/pubmed/29903733
- Salvermoser M, Pick R, Weckbach LT, Zehrer A, Lohr P, Drechsler M, Sperandio M, Soehnlein O, Walzog B. Myosin 1f is specifically required for neutrophil migration in 3D environments during acute inflammation. Blood 2018; 131(17): 1887-1898. https://www.ncbi.nlm.nih.gov/pubmed/29487067
- Schmitz C, Noels H, El Bounkari O, Straussfeld E, Megens RTA, Sternkopf M, Alampour-Rajabi S, Krammer C, Tilstam PV, Gerdes N, Burger C, Kapurniotu A, Bucala R, Jankowski J, Weber C, Bernhagen J. Mif-deficiency favors an atheroprotective autoantibody phenotype in atherosclerosis. FASEB J 2018; 32(8): 4428-4443. https://www.ncbi.nlm.nih.gov/pubmed/29543531
- Schonhoff M, Weineck G, Hoppe J, Hornig S, Cordts K, Atzler D, Gerloff C, Boger R, Neu A, Schwedhelm E, Choe CU. Cognitive performance of 20 healthy humans supplemented with L-homoarginine for 4 weeks. J Clin Neurosci 2018; 50: 237-241. https://www.ncbi.nlm.nih.gov/pubmed/29396070
- Schumski A, Winter C, Doring Y, Soehnlein O. The Ins and Outs of Myeloid Cells in Atherosclerosis. J Innate Immun 2018; 10(5-6): 479-486. https://www.ncbi.nlm.nih.gov/pubmed/29669334
- Seijkens TTP, Lutgens E. Cardiovascular oncology: exploring the effects of targeted cancer therapies on atherosclerosis. Curr Opin Lipidol 2018; 29(5): 381-388. https://www.ncbi.nlm.nih.gov/pubmed/30074493
- Seijkens TTP, van Tiel CM, Kusters PJH, Atzler D, Soehnlein O, Zarzycka B, Aarts S, Lameijer M, Gijbels MJ, Beckers L, den Toom M, Slutter B, Kuiper J, Duchene J, Aslani M, Megens RTA, van 't Veer C, Kooij G, Schrijver R, Hoeksema MA, Boon L, Fay F, Tang J, Baxter S, Jongejan A, Moerland PD, Vriend G, Bleijlevens B, Fisher EA, Duivenvoorden R, Gerdes N, de Winther MPJ, Nicolaes GA, Mulder WJM, Weber C, Lutgens E. Targeting CD40-Induced TRAF6 Signaling in Macrophages Reduces Atherosclerosis. J Am Coll Cardiol 2018; 71(5): 527-542. https://www.ncbi.nlm.nih.gov/pubmed/29406859
- Soehnlein O. [Atherothrombosis : Novel therapeutic strategies]. Herz 2018; 43(2): 103-108. https://www.ncbi.nlm.nih.gov/pubmed/29236146
- Soehnlein O. Decision shaping neutrophil-platelet interplay in inflammation: From physiology to intervention. Eur J Clin Invest 2018; 48(2). https://www.ncbi.nlm.nih.gov/pubmed/29226390
- Soehnlein O, Bazioti V, Westerterp M. A Pad 4 Plaque Erosion. Circ Res 2018; 123(1): 6-8. https://www.ncbi.nlm.nih.gov/pubmed/29929967
- Steven S, Dib M, Hausding M, Kashani F, Oelze M, Kroller-Schon S, Hanf A, Daub S, Roohani S, Gramlich Y, Lutgens E, Schulz E, Becker C, Lackner KJ, Kleinert H, Knosalla C, Niesler B, Wild PS, Munzel T, Daiber A. CD40L controls obesity-associated vascular inflammation, oxidative stress, and endothelial dysfunction in high fat diet-treated and db/db mice. Cardiovasc Res 2018; 114(2): 312-323. https://www.ncbi.nlm.nih.gov/pubmed/29036612
- Stocker TJ, Pircher J, Skenderi A, Ehrlich A, Eberle C, Megens RTA, Petzold T, Zhang Z, Walzog B, Muller-Taubenberger A, Weber C, Massberg S, Ishikawa-Ankerhold H, Schulz C. The Actin Regulator Coronin-1A Modulates Platelet Shape Change and Consolidates Arterial Thrombosis. Thromb Haemost 2018; 118(12): 2098-2111. https://www.ncbi.nlm.nih.gov/pubmed/30453345
- Trevino-Villarreal JH, Reynolds JS, Bartelt A, Langston PK, MacArthur MR, Arduini A, Tosti V, Veronese N, Bertozzi B, Brace LE, Mejia P, Trocha K, Kajitani GS, Longchamp A, Harputlugil E, Gathungu R, Bird SS, Bullock AD, Figenshau RS, Andriole GL, Thompson A, Heeren J, Ozaki CK, Kristal BS, Fontana L, Mitchell JR. Dietary protein restriction reduces circulating VLDL triglyceride levels via CREBH-APOA5-dependent and -independent mechanisms. JCI Insight 2018; 3(21): e99470. https://www.ncbi.nlm.nih.gov/pubmed/30385734
- Tunon J, Back M, Badimon L, Bochaton-Piallat ML, Cariou B, Daemen MJ, Egido J, Evans PC, Francis SE, Ketelhuth DF, Lutgens E, Matter CM, Monaco C, Steffens S, Stroes E, Vindis C, Weber C, Hoefer IE, Atherosclerosis ESCWGo, Vascular B. Interplay between hypercholesterolaemia and inflammation in atherosclerosis: Translating experimental targets into clinical practice. Eur J Prev Cardiol 2018; 25(9): 948-955. https://www.ncbi.nlm.nih.gov/pubmed/29759006
- Vajen T, Koenen RR, Werner I, Staudt M, Projahn D, Curaj A, Sonmez TT, Simsekyilmaz S, Schumacher D, Mollmann J, Hackeng TM, Hundelshausen PV, Weber C, Liehn EA. Blocking CCL5-CXCL4 heteromerization preserves heart function after myocardial infarction by attenuating leukocyte recruitment and NETosis. Sci Rep 2018; 8(1): 10647. https://www.ncbi.nlm.nih.gov/pubmed/30006564
- van der Tuin SJL, Li Z, Berbee JFP, Verkouter I, Ringnalda LE, Neele AE, van Klinken JB, Rensen SS, Fu J, de Winther MPJ, Groen AK, Rensen PCN, Willems van Dijk K, Wang Y. Lipopolysaccharide Lowers Cholesteryl Ester Transfer Protein by Activating F4/80(+)Clec4f(+)Vsig4(+)Ly6C(-) Kupffer Cell Subsets. J Am Heart Assoc 2018; 7(6): e008105. https://www.ncbi.nlm.nih.gov/pubmed/29525783
- van der Vorst EPC, Weber C, Donners M. A Disintegrin and Metalloproteases (ADAMs) in Cardiovascular, Metabolic and Inflammatory Diseases: Aspects for Theranostic Approaches. Thromb Haemost 2018; 118(7): 1167-1175. https://www.ncbi.nlm.nih.gov/pubmed/29874690
- van der Vorst EPC, de Jong RJ, Donners M. Message in a Microbottle: Modulation of Vascular Inflammation and Atherosclerosis by Extracellular Vesicles. Front Cardiovasc Med 2018; 5: 2. https://www.ncbi.nlm.nih.gov/pubmed/29404342
- van der Vorst EPC, Doring Y. Resistin keeps its Janus face. Int J Cardiol 2018; 272: 47-48. https://www.ncbi.nlm.nih.gov/pubmed/30180984
- van der Vorst EPC, Weber C. Metabolomic profiling of atherosclerotic plaques: towards improved cardiovascular risk stratification. Eur Heart J 2018; 39(24): 2311-2313. https://www.ncbi.nlm.nih.gov/pubmed/29562256
- Vinketova capital Ka C, Karagyozov I, Koleva V, Hristov M, Mourdjeva M, Sperandio M, Oreshkova T. Progesterone and cyclic adenosine monophosphate down-regulate CD90 in the stromal cells of human decidua. In vitro evidence and in situ findings. Am J Reprod Immunol 2018; 80(5): e13043. https://www.ncbi.nlm.nih.gov/pubmed/30151982
- Viola JR, Lemnitzer P, Paulin N, Drechsler M, Nazari-Jahantigh M, Maas S, De Jong RJ, Winter J, Schober A, Weber C, Atabai K, Soehnlein O. Deletion of MFGE8 Inhibits Neointima Formation upon Arterial Damage. Thromb Haemost 2018; 118(7): 1340-1342. https://www.ncbi.nlm.nih.gov/pubmed/29864782
- Wang W, Liu W, Fidler T, Wang Y, Tang Y, Woods B, Welch C, Cai B, Silvestre-Roig C, Ai D, Yang YG, Hidalgo A, Soehnlein O, Tabas I, Levine RL, Tall AR, Wang N. Macrophage Inflammation, Erythrophagocytosis, and Accelerated Atherosclerosis in Jak2 (V617F) Mice. Circ Res 2018; 123(11): e35-e47. https://www.ncbi.nlm.nih.gov/pubmed/30571460
- Wei Y, Corbalan-Campos J, Gurung R, Natarelli L, Zhu M, Exner N, Erhard F, Greulich F, Geissler C, Uhlenhaut NH, Zimmer R, Schober A. Dicer in Macrophages Prevents Atherosclerosis by Promoting Mitochondrial Oxidative Metabolism. Circulation 2018; 138(18): 2007-2020. https://www.ncbi.nlm.nih.gov/pubmed/29748186
- Wei Y, Zhu M, Schober A. Macrophage MicroRNAs as Therapeutic Targets for Atherosclerosis, Metabolic Syndrome, and Cancer. Int J Mol Sci 2018; 19(6): 1756. https://www.ncbi.nlm.nih.gov/pubmed/29899293
- Williams JW, Martel C, Potteaux S, Esaulova E, Ingersoll MA, Elvington A, Saunders BT, Huang LH, Habenicht AJ, Zinselmeyer BH, Randolph GJ. Limited Macrophage Positional Dynamics in Progressing or Regressing Murine Atherosclerotic Plaques-Brief Report. Arterioscler Thromb Vasc Biol 2018; 38(8): 1702-1710. https://www.ncbi.nlm.nih.gov/pubmed/29903736
- Winter C, Silvestre-Roig C, Ortega-Gomez A, Lemnitzer P, Poelman H, Schumski A, Winter J, Drechsler M, de Jong R, Immler R, Sperandio M, Hristov M, Zeller T, Nicolaes GAF, Weber C, Viola JR, Hidalgo A, Scheiermann C, Soehnlein O. Chrono-pharmacological Targeting of the CCL2-CCR2 Axis Ameliorates Atherosclerosis. Cell Metab 2018; 28(1): 175-182 e175. https://www.ncbi.nlm.nih.gov/pubmed/29861387
- Winter C, Soehnlein O. The potential of chronopharmacology for treatment of atherosclerosis. Curr Opin Lipidol 2018; 29(5): 368-374. https://www.ncbi.nlm.nih.gov/pubmed/30063471
- Winter C, Soehnlein O, Maegdefessel L. TIMPing the Aorta: Smooth Muscle Cell-Specific Deletion of BMAL1 Limits Murine Abdominal Aortic Aneurysm Development. Arterioscler Thromb Vasc Biol 2018; 38(5): 982-983. https://www.ncbi.nlm.nih.gov/pubmed/29695531
- Zhou Z, Schober A, Nazari-Jahantigh M. Dicer promotes endothelial recovery and limits lesion formation after vascular injury through miR-126-5p. Int J Cardiol 2018; 273: 199-202. https://www.ncbi.nlm.nih.gov/pubmed/30213595
- Ziegler T, Bahr A, Howe A, Klett K, Husada W, Weber C, Laugwitz KL, Kupatt C, Hinkel R. Tbeta4 Increases Neovascularization and Cardiac Function in Chronic Myocardial Ischemia of Normo- and Hypercholesterolemic Pigs. Mol Ther 2018; 26(7): 1706-1714. https://www.ncbi.nlm.nih.gov/pubmed/29929787
- Ziegler T, Hinkel R, Kupatt C. Induced pluripotent stem cell derived cardiac models: effects of Thymosin beta4. Expert Opin Biol Ther 2018; 18(sup1): 111-120. https://www.ncbi.nlm.nih.gov/pubmed/30063852
- A-Gonzalez N, Quintana JA, Garcia-Silva S, Mazariegos M, Gonzalez de la Aleja A, Nicolas-Avila JA, Walter W, Adrover JM, Crainiciuc G, Kuchroo VK, Rothlin CV, Peinado H, Castrillo A, Ricote M, Hidalgo A. Phagocytosis imprints heterogeneity in tissue-resident macrophages. J Exp Med 2017; 214(5): 1281-96. https://www.ncbi.nlm.nih.gov/pubmed/28432199
- Aarts S, Seijkens TTP, Kusters PJH, van der Pol SMA, Zarzycka B, Heijnen P, Beckers L, den Toom M, Gijbels MJJ, Boon L, Weber C, de Vries HE, Nicolaes GAF, Dijkstra CD, Kooij G, Lutgens E. Inhibition of CD40-TRAF6 interactions by the small molecule inhibitor 6877002 reduces neuroinflammation. J Neuroinflammation 2017; 14(1): 105. https://www.ncbi.nlm.nih.gov/pubmed/28494768
- Aarts S, Seijkens TTP, van Dorst KJF, Dijkstra CD, Kooij G, Lutgens E. The CD40-CD40L Dyad in Experimental Autoimmune Encephalomyelitis and Multiple Sclerosis. Front Immunol 2017; 8: 1791. https://www.ncbi.nlm.nih.gov/pubmed/29312317
- Asare Y, Ommer M, Azombo FA, Alampour-Rajabi S, Sternkopf M, Sanati M, Gijbels MJ, Schmitz C, Sinitski D, Tilstam PV, Lue H, Gessner A, Lange D, Schmid JA, Weber C, Dichgans M, Jankowski J, Pardi R, de Winther MP, Noels H, Bernhagen J. Inhibition of atherogenesis by the COP9 signalosome subunit 5 in vivo. Proc Natl Acad Sci U S A 2017; 114(13): E2766-E75. https://www.ncbi.nlm.nih.gov/pubmed/28292897
- Atzler D, McAndrew DJ, Cordts K, Schneider JE, Zervou S, Schwedhelm E, Neubauer S, Lygate CA. Dietary Supplementation with Homoarginine Preserves Cardiac Function in a Murine Model of Post-Myocardial Infarction Heart Failure. Circulation 2017; 135(4): 400-2. https://www.ncbi.nlm.nih.gov/pubmed/28115416
- Bamberg F, Hetterich H, Rospleszcz S, Lorbeer R, Auweter SD, Schlett CL, Schafnitzel A, Bayerl C, Schindler A, Saam T, Muller-Peltzer K, Sommer W, Zitzelsberger T, Machann J, Ingrisch M, Selder S, Rathmann W, Heier M, Linkohr B, Meisinger C, Weber C, Ertl-Wagner B, Massberg S, Reiser MF, Peters A. Subclinical Disease Burden as Assessed by Whole-Body MRI in Subjects With Prediabetes, Subjects With Diabetes, and Normal Control Subjects From the General Population: The KORA-MRI Study. Diabetes 2017; 66(1): 158-69. https://www.ncbi.nlm.nih.gov/pubmed/27999110
- Barthels C, Ogrinc A, Steyer V, Meier S, Simon F, Wimmer M, Blutke A, Straub T, Zimber-Strobl U, Lutgens E, Marconi P, Ohnmacht C, Garzetti D, Stecher B, Brocker T. CD40-signalling abrogates induction of RORgammat(+) Treg cells by intestinal CD103(+) DCs and causes fatal colitis. Nat Commun 2017; 8: 14715. https://www.ncbi.nlm.nih.gov/pubmed/28276457
- Beldman TJ, Senders ML, Alaarg A, Perez-Medina C, Tang J, Zhao Y, Fay F, Deichmoller J, Born B, Desclos E, van der Wel NN, Hoebe RA, Kohen F, Kartvelishvily E, Neeman M, Reiner T, Calcagno C, Fayad ZA, de Winther MPJ, Lutgens E, Mulder WJM, Kluza E. Hyaluronan Nanoparticles Selectively Target Plaque-Associated Macrophages and Improve Plaque Stability in Atherosclerosis. ACS Nano 2017; 11(6): 5785-99. https://www.ncbi.nlm.nih.gov/pubmed/28463501
- Bermudez B, Dahl TB, Medina I, Groeneweg M, Holm S, Montserrat-de la Paz S, Rousch M, Otten J, Herias V, Varela LM, Ranheim T, Yndestad A, Ortega-Gomez A, Abia R, Nagy L, Aukrust P, Muriana FJG, Halvorsen B, Biessen EAL. Leukocyte Overexpression of Intracellular NAMPT Attenuates Atherosclerosis by Regulating PPARgamma-Dependent Monocyte Differentiation and Function. Arterioscler Thromb Vasc Biol 2017; 37(6): 1157-67. https://www.ncbi.nlm.nih.gov/pubmed/28408371
- Bernelot Moens SJ, Neele AE, Kroon J, van der Valk FM, Van den Bossche J, Hoeksema MA, Hoogeveen RM, Schnitzler JG, Baccara-Dinet MT, Manvelian G, de Winther MPJ, Stroes ESG. PCSK9 monoclonal antibodies reverse the pro-inflammatory profile of monocytes in familial hypercholesterolaemia. Eur Heart J 2017; 38(20): 1584-93. https://www.ncbi.nlm.nih.gov/pubmed/28329114
- Chen Z, Xian W, Bellin M, Dorn T, Tian Q, Goedel A, Dreizehnter L, Schneider CM, Ward-van Oostwaard D, Ng JK, Hinkel R, Pane LS, Mummery CL, Lipp P, Moretti A, Laugwitz KL, Sinnecker D. Subtype-specific promoter-driven action potential imaging for precise disease modelling and drug testing in hiPSC-derived cardiomyocytes. Eur Heart J 2017; 38(4): 292-301. https://www.ncbi.nlm.nih.gov/pubmed/28182242
- Cheng HS, Besla R, Li A, Chen Z, Shikatani EA, Nazari-Jahantigh M, Hammoutene A, Nguyen MA, Geoffrion M, Cai L, Khyzha N, Li T, MacParland SA, Husain M, Cybulsky MI, Boulanger CM, Temel RE, Schober A, Rayner KJ, Robbins CS, Fish JE. Paradoxical Suppression of Atherosclerosis in the Absence of microRNA-146a. Circ Res 2017; 121(4): 354-67. https://www.ncbi.nlm.nih.gov/pubmed/28637783
- de Jong R, Leoni G, Drechsler M, Soehnlein O. The advantageous role of annexin A1 in cardiovascular disease. Cell Adh Migr 2017; 11(3): 261-74. https://www.ncbi.nlm.nih.gov/pubmed/27860536
- de Jong RJ, Paulin N, Lemnitzer P, Viola JR, Winter C, Ferraro B, Grommes J, Weber C, Reutelingsperger C, Drechsler M, Soehnlein O. Protective Aptitude of Annexin A1 in Arterial Neointima Formation in Atherosclerosis-Prone Mice-Brief Report. Arterioscler Thromb Vasc Biol 2017; 37(2): 312-5. https://www.ncbi.nlm.nih.gov/pubmed/28062503
- Degen H, Borst O, Ziegler M, Mojica Munoz AK, Jamasbi J, Walker B, Gobel S, Fassbender J, Adler K, Brandl R, Munch G, Lorenz R, Siess W, Gawaz M, Ungerer M. ADPase CD39 Fused to Glycoprotein VI-Fc Boosts Local Antithrombotic Effects at Vascular Lesions. J Am Heart Assoc 2017; 6(8): e005991. https://www.ncbi.nlm.nih.gov/pubmed/28751543
- Doring Y, Noels H, van der Vorst EPC, Neideck C, Egea V, Drechsler M, Mandl M, Pawig L, Jansen Y, Schroder K, Bidzhekov K, Megens RTA, Theelen W, Klinkhammer BM, Boor P, Schurgers L, van Gorp R, Ries C, Kusters PJH, van der Wal A, Hackeng TM, Gabel G, Brandes RP, Soehnlein O, Lutgens E, Vestweber D, Teupser D, Holdt LM, Rader DJ, Saleheen D, Weber C. Vascular CXCR4 Limits Atherosclerosis by Maintaining Arterial Integrity: Evidence From Mouse and Human Studies. Circulation 2017; 136(4): 388-403. https://www.ncbi.nlm.nih.gov/pubmed/28450349
- Doring Y, Soehnlein O, Weber C. Neutrophil Extracellular Traps in Atherosclerosis and Atherothrombosis. Circ Res 2017; 120(4): 736-43. https://www.ncbi.nlm.nih.gov/pubmed/28209798
- Duchene J, Novitzky-Basso I, Thiriot A, Casanova-Acebes M, Bianchini M, Etheridge SL, Hub E, Nitz K, Artinger K, Eller K, Caamano J, Rulicke T, Moss P, Megens RTA, von Andrian UH, Hidalgo A, Weber C, Rot A. Atypical chemokine receptor 1 on nucleated erythroid cells regulates hematopoiesis. Nat Immunol 2017; 18(7): 753-61. https://www.ncbi.nlm.nih.gov/pubmed/28553950
- Enamorado M, Iborra S, Priego E, Cueto FJ, Quintana JA, Martinez-Cano S, Mejias-Perez E, Esteban M, Melero I, Hidalgo A, Sancho D. Enhanced anti-tumour immunity requires the interplay between resident and circulating memory CD8(+) T cells. Nat Commun 2017; 8: 16073. https://www.ncbi.nlm.nih.gov/pubmed/28714465
- Feng S, Bowden N, Fragiadaki M, Souilhol C, Hsiao S, Mahmoud M, Allen S, Pirri D, Ayllon BT, Akhtar S, Thompson AAR, Jo H, Weber C, Ridger V, Schober A, Evans PC. Mechanical Activation of Hypoxia-Inducible Factor 1alpha Drives Endothelial Dysfunction at Atheroprone Sites. Arterioscler Thromb Vasc Biol 2017; 37(11): 2087-101. https://www.ncbi.nlm.nih.gov/pubmed/28882872
- Ferrari E, Lutgens E, Weber C, Gerdes N. Atherosclerosis: cell biology and lipoproteins focus on epigenetic modification and macrophage biology. Curr Opin Lipidol 2017; 28(2): 220-1. https://www.ncbi.nlm.nih.gov/pubmed/28272157
- Garg G, Nikolouli E, Hardtke-Wolenski M, Toker A, Ohkura N, Beckstette M, Miyao T, Geffers R, Floess S, Gerdes N, Lutgens E, Osterloh A, Hori S, Sakaguchi S, Jaeckel E, Huehn J. Unique properties of thymic antigen-presenting cells promote epigenetic imprinting of alloantigen-specific regulatory T cells. Oncotarget 2017; 8(22): 35542-57. https://www.ncbi.nlm.nih.gov/pubmed/28415767
- Hakimzadeh N, Pinas VA, Molenaar G, de Waard V, Lutgens E, van Eck-Smit BLF, de Bruin K, Piek JJ, Eersels JLH, Booij J, Verberne HJ, Windhorst AD. Novel molecular imaging ligands targeting matrix metalloproteinases 2 and 9 for imaging of unstable atherosclerotic plaques. PLoS One 2017; 12(11): e0187767. https://www.ncbi.nlm.nih.gov/pubmed/29190653
- Horckmans M, Ring L, Duchene J, Santovito D, Schloss MJ, Drechsler M, Weber C, Soehnlein O, Steffens S. Neutrophils orchestrate post-myocardial infarction healing by polarizing macrophages towards a reparative phenotype. Eur Heart J 2017; 38(3): 187-97. https://www.ncbi.nlm.nih.gov/pubmed/28158426
- Hyafil F, Pelisek J, Laitinen I, Schottelius M, Mohring M, Doring Y, van der Vorst EP, Kallmayer M, Steiger K, Poschenrieder A, Notni J, Fischer J, Baumgartner C, Rischpler C, Nekolla SG, Weber C, Eckstein HH, Wester HJ, Schwaiger M. Imaging the Cytokine Receptor CXCR4 in Atherosclerotic Plaques with the Radiotracer (68)Ga-Pentixafor for PET. J Nucl Med 2017; 58(3): 499-506. https://www.ncbi.nlm.nih.gov/pubmed/27789718
- Jamasbi J, Ayabe K, Goto S, Nieswandt B, Peter K, Siess W. Platelet receptors as therapeutic targets: Past, present and future. Thromb Haemost 2017; 117(7): 1249-57. https://www.ncbi.nlm.nih.gov/pubmed/28597906
- Jung C, Lichtenauer M, Strodthoff D, Winkels H, Wernly B, Burger C, Kamchybekov U, Lutgens E, Figulla HR, Gerdes N. Alterations in systemic levels of Th1, Th2, and Th17 cytokines in overweight adolescents and obese mice. Pediatr Diabetes 2017; 18(8): 714-21. https://www.ncbi.nlm.nih.gov/pubmed/27597513
- Krishnasamy K, Limbourg A, Kapanadze T, Gamrekelashvili J, Beger C, Hager C, Lozanovski VJ, Falk CS, Napp LC, Bauersachs J, Mack M, Haller H, Weber C, Adams RH, Limbourg FP. Blood vessel control of macrophage maturation promotes arteriogenesis in ischemia. Nat Commun 2017; 8(1): 952. https://www.ncbi.nlm.nih.gov/pubmed/29038527
- Kusters P, Seijkens T, Burger C, Legein B, Winkels H, Gijbels M, Barthels C, Bennett R, Beckers L, Atzler D, Biessen E, Brocker T, Weber C, Gerdes N, Lutgens E. Constitutive CD40 Signaling in Dendritic Cells Limits Atherosclerosis by Provoking Inflammatory Bowel Disease and Ensuing Cholesterol Malabsorption. Am J Pathol 2017; 187(12): 2912-9. https://www.ncbi.nlm.nih.gov/pubmed/28935569
- Ley K, Gerdes N, Winkels H. ATVB Distinguished Scientist Award: How Costimulatory and Coinhibitory Pathways Shape Atherosclerosis. Arterioscler Thromb Vasc Biol 2017; 37(5): 764-77. https://www.ncbi.nlm.nih.gov/pubmed/28360089
- Li JL, Zarbock A, Hidalgo A. Platelets as autonomous drones for hemostatic and immune surveillance. J Exp Med 2017; 214(8): 2193-204. https://www.ncbi.nlm.nih.gov/pubmed/28720569
- Lip GY, Weber C. A happy and prosperous New Year 2017 with "Thrombosis and Haemostasis" .... and our 60(th) Anniversary! Thromb Haemost 2017; 117(1): 1-2. https://www.ncbi.nlm.nih.gov/pubmed/28066853
- Lip GYH, Weber C. Thrombosis and Haemostasis: Past, present and future. Thromb Haemost 2017; 117(7): 1217-8. https://www.ncbi.nlm.nih.gov/pubmed/30457155
- Maffia P, Doring Y, Biessen EA, Mallat Z. Commentary: Indoleamine 2,3-Dioxygenase-Expressing Aortic Plasmacytoid Dendritic Cells Protect against Atherosclerosis by Induction of Regulatory T Cells. Front Immunol 2017; 8: 140. https://www.ncbi.nlm.nih.gov/pubmed/28243244
- Mitroulis I, Chen LS, Singh RP, Kourtzelis I, Economopoulou M, Kajikawa T, Troullinaki M, Ziogas A, Ruppova K, Hosur K, Maekawa T, Wang B, Subramanian P, Tonn T, Verginis P, von Bonin M, Wobus M, Bornhauser M, Grinenko T, Di Scala M, Hidalgo A, Wielockx B, Hajishengallis G, Chavakis T. Secreted protein Del-1 regulates myelopoiesis in the hematopoietic stem cell niche. J Clin Invest 2017; 127(10): 3624-39. https://www.ncbi.nlm.nih.gov/pubmed/28846069
- Mojica Munoz AK, Jamasbi J, Uhland K, Degen H, Munch G, Ungerer M, Brandl R, Megens R, Weber C, Lorenz R, Siess W. Recombinant GPVI-Fc added to single or dual antiplatelet therapy in vitro prevents plaque-induced platelet thrombus formation. Thromb Haemost 2017; 117(8): 1651-9. https://www.ncbi.nlm.nih.gov/pubmed/28569920
- Neele AE, Prange KH, Hoeksema MA, van der Velden S, Lucas T, Dimmeler S, Lutgens E, Van den Bossche J, de Winther MP. Macrophage Kdm6b controls the pro-fibrotic transcriptome signature of foam cells. Epigenomics 2017; 9(4): 383-91. https://www.ncbi.nlm.nih.gov/pubmed/28322580
- Newland SA, Mohanta S, Clement M, Taleb S, Walker JA, Nus M, Sage AP, Yin C, Hu D, Kitt LL, Finigan AJ, Rodewald HR, Binder CJ, McKenzie ANJ, Habenicht AJ, Mallat Z. Type-2 innate lymphoid cells control the development of atherosclerosis in mice. Nat Commun 2017; 8: 15781. https://www.ncbi.nlm.nih.gov/pubmed/28589929
- Nicolaou A, Zhao Z, Northoff BH, Sass K, Herbst A, Kohlmaier A, Chalaris A, Wolfrum C, Weber C, Steffens S, Rose-John S, Teupser D, Holdt LM. Adam17 Deficiency Promotes Atherosclerosis by Enhanced TNFR2 Signaling in Mice. Arterioscler Thromb Vasc Biol 2017; 37(2): 247-57. https://www.ncbi.nlm.nih.gov/pubmed/28062509
- Nicolas-Avila JA, Adrover JM, Hidalgo A. Neutrophils in Homeostasis, Immunity, and Cancer. Immunity 2017; 46(1): 15-28. https://www.ncbi.nlm.nih.gov/pubmed/28099862
- Paulin N, Doring Y, Kooijman S, Blanchet X, Viola JR, de Jong R, Mandl M, Hendrikse J, Schiener M, von Hundelshausen P, Vogt A, Weber C, Bdeir K, Hofmann SM, Rensen PCN, Drechsler M, Soehnlein O. Human Neutrophil Peptide 1 Limits Hypercholesterolemia-induced Atherosclerosis by Increasing Hepatic LDL Clearance. EBioMedicine 2017; 16: 204-11. https://www.ncbi.nlm.nih.gov/pubmed/28111237
- Pellico J, Lechuga-Vieco AV, Almarza E, Hidalgo A, Mesa-Nunez C, Fernandez-Barahona I, Quintana JA, Bueren J, Enriquez JA, Ruiz-Cabello J, Herranz F. In vivo imaging of lung inflammation with neutrophil-specific (68)Ga nano-radiotracer. Sci Rep 2017; 7(1): 13242. https://www.ncbi.nlm.nih.gov/pubmed/29038592
- Quiros M, Nishio H, Neumann PA, Siuda D, Brazil JC, Azcutia V, Hilgarth R, O'Leary MN, Garcia-Hernandez V, Leoni G, Feng M, Bernal G, Williams H, Dedhia PH, Gerner-Smidt C, Spence J, Parkos CA, Denning TL, Nusrat A. Macrophage-derived IL-10 mediates mucosal repair by epithelial WISP-1 signaling. J Clin Invest 2017; 127(9): 3510-20. https://www.ncbi.nlm.nih.gov/pubmed/28783045
- Rademakers T, van der Vorst EP, Daissormont IT, Otten JJ, Theodorou K, Theelen TL, Gijbels M, Anisimov A, Nurmi H, Lindeman JH, Schober A, Heeneman S, Alitalo K, Biessen EA. Adventitial lymphatic capillary expansion impacts on plaque T cell accumulation in atherosclerosis. Sci Rep 2017; 7: 45263. https://www.ncbi.nlm.nih.gov/pubmed/28349940
- Ridger VC, Boulanger CM, Angelillo-Scherrer A, Badimon L, Blanc-Brude O, Bochaton-Piallat ML, Boilard E, Buzas EI, Caporali A, Dignat-George F, Evans PC, Lacroix R, Lutgens E, Ketelhuth DFJ, Nieuwland R, Toti F, Tunon J, Weber C, Hoefer IE. Microvesicles in vascular homeostasis and diseases. Position Paper of the European Society of Cardiology (ESC) Working Group on Atherosclerosis and Vascular Biology. Thromb Haemost 2017; 117(7): 1296-316. https://www.ncbi.nlm.nih.gov/pubmed/28569921
- Rinne P, Rami M, Nuutinen S, Santovito D, van der Vorst EPC, Guillamat-Prats R, Lyytikainen LP, Raitoharju E, Oksala N, Ring L, Cai M, Hruby VJ, Lehtimaki T, Weber C, Steffens S. Melanocortin 1 Receptor Signaling Regulates Cholesterol Transport in Macrophages. Circulation 2017; 136(1): 83-97. https://www.ncbi.nlm.nih.gov/pubmed/28450348
- Rowinska Z, Koeppel TA, Sanati M, Schelzig H, Jankowski J, Weber C, Zernecke A, Liehn EA. Role of the CX3C chemokine receptor CX3CR1 in the pathogenesis of atherosclerosis after aortic transplantation. PLoS One 2017; 12(2): e0170644. https://www.ncbi.nlm.nih.gov/pubmed/28234900
- Santovito D. Fat or fit: The big oxymoron of (metabolically) healthy obesity. Atherosclerosis 2017; 262: 143-5. https://www.ncbi.nlm.nih.gov/pubmed/28499608
- Santovito D, Weber C. Atherosclerosis revisited from a clinical perspective: still an inflammatory disease? Thromb Haemost 2017; 117(2): 231-7. https://www.ncbi.nlm.nih.gov/pubmed/27975102
- Santovito D, Weber C. Zooming in on microRNAs for refining cardiovascular risk prediction in secondary prevention. Eur Heart J 2017; 38(7): 524-8. https://www.ncbi.nlm.nih.gov/pubmed/27371715
- Schloss MJ, Hilby M, Nitz K, Guillamat Prats R, Ferraro B, Leoni G, Soehnlein O, Kessler T, He W, Luckow B, Horckmans M, Weber C, Duchene J, Steffens S. Ly6C(high) Monocytes Oscillate in the Heart During Homeostasis and After Myocardial Infarction-Brief Report. Arterioscler Thromb Vasc Biol 2017; 37(9): 1640-5. https://www.ncbi.nlm.nih.gov/pubmed/28663258
- Soehnlein O, Silvestre-Roig C. Basic research: Standardizing animal atherosclerosis studies to improve reproducibility. Nat Rev Cardiol 2017; 14(10): 574-5. https://www.ncbi.nlm.nih.gov/pubmed/28880022
- Soehnlein O, Steffens S, Hidalgo A, Weber C. Neutrophils as protagonists and targets in chronic inflammation. Nat Rev Immunol 2017; 17(4): 248-61. https://www.ncbi.nlm.nih.gov/pubmed/28287106
- Steffens S, Winter C, Schloss MJ, Hidalgo A, Weber C, Soehnlein O. Circadian Control of Inflammatory Processes in Atherosclerosis and Its Complications. Arterioscler Thromb Vasc Biol 2017; 37(6): 1022-8. https://www.ncbi.nlm.nih.gov/pubmed/28450299
- Theodorou K, van der Vorst EPC, Gijbels MJ, Wolfs IMJ, Jeurissen M, Theelen TL, Sluimer JC, Wijnands E, Cleutjens JP, Li Y, Jansen Y, Weber C, Ludwig A, Bentzon JF, Bartsch JW, Biessen EAL, Donners M. Whole body and hematopoietic ADAM8 deficiency does not influence advanced atherosclerotic lesion development, despite its association with human plaque progression. Sci Rep 2017; 7(1): 11670. https://www.ncbi.nlm.nih.gov/pubmed/28916789
- Tufanli O, Telkoparan Akillilar P, Acosta-Alvear D, Kocaturk B, Onat UI, Hamid SM, Cimen I, Walter P, Weber C, Erbay E. Targeting IRE1 with small molecules counteracts progression of atherosclerosis. Proc Natl Acad Sci U S A 2017; 114(8): E1395-E404. https://www.ncbi.nlm.nih.gov/pubmed/28137856
- van den Berg SM, van Dam AD, Kusters PJH, Beckers L, den Toom M, van der Velden S, Van den Bossche J, van Die I, Boon MR, Rensen PCN, Lutgens E, de Winther MPJ. Helminth antigens counteract a rapid high-fat diet-induced decrease in adipose tissue eosinophils. J Mol Endocrinol 2017; 59(3): 245-55. https://www.ncbi.nlm.nih.gov/pubmed/28694301
- van den Berg SM, van Dam AD, Rensen PC, de Winther MP, Lutgens E. Immune Modulation of Brown(ing) Adipose Tissue in Obesity. Endocr Rev 2017; 38(1): 46-68. https://www.ncbi.nlm.nih.gov/pubmed/27849358
- van der Vorst EP, Zhao Z, Rami M, Holdt LM, Teupser D, Steffens S, Weber C. Contrasting effects of myeloid and endothelial ADAM17 on atherosclerosis development. Thromb Haemost 2017; 117(3): 644-6. https://www.ncbi.nlm.nih.gov/pubmed/28004058
- van der Vorst EPC, Maas SL, Ortega-Gomez A, Hameleers JMM, Bianchini M, Asare Y, Soehnlein O, Doring Y, Weber C, Megens RTA. Functional ex-vivo Imaging of Arterial Cellular Recruitment and Lipid Extravasation. Bio Protoc 2017; 7(12): e2344. https://www.ncbi.nlm.nih.gov/pubmed/28890907
- van der Vorst EPC, Theodorou K, Biessen EAL, Donners M. HDL and macrophages: explaining the clinical failures and advancing HDL-based therapeutics in cardiovascular diseases? Expert Rev Cardiovasc Ther 2017; 15(5): 343-4. https://www.ncbi.nlm.nih.gov/pubmed/28349717
- van der Vorst EPC, Theodorou K, Wu Y, Hoeksema MA, Goossens P, Bursill CA, Aliyev T, Huitema LFA, Tas SW, Wolfs IMJ, Kuijpers MJE, Gijbels MJ, Schalkwijk CG, Koonen DPY, Abdollahi-Roodsaz S, McDaniels K, Wang CC, Leitges M, Lawrence T, Plat J, Van Eck M, Rye KA, Touqui L, de Winther MPJ, Biessen EAL, Donners M. High-Density Lipoproteins Exert Pro-inflammatory Effects on Macrophages via Passive Cholesterol Depletion and PKC-NF-kappaB/STAT1-IRF1 Signaling. Cell Metab 2017; 25(1): 197-207. https://www.ncbi.nlm.nih.gov/pubmed/27866837
- Varasteh Z, Hyafil F, Anizan N, Diallo D, Aid-Launais R, Mohanta S, Li Y, Braeuer M, Steiger K, Vigne J, Qin Z, Nekolla SG, Fabre JE, Doring Y, Le Guludec D, Habenicht A, Vera DR, Schwaiger M. Targeting mannose receptor expression on macrophages in atherosclerotic plaques of apolipoprotein E-knockout mice using (111)In-tilmanocept. EJNMMI Res 2017; 7(1): 40. https://www.ncbi.nlm.nih.gov/pubmed/28470406
- von Hundelshausen P, Agten SM, Eckardt V, Blanchet X, Schmitt MM, Ippel H, Neideck C, Bidzhekov K, Leberzammer J, Wichapong K, Faussner A, Drechsler M, Grommes J, van Geffen JP, Li H, Ortega-Gomez A, Megens RT, Naumann R, Dijkgraaf I, Nicolaes GA, Doring Y, Soehnlein O, Lutgens E, Heemskerk JW, Koenen RR, Mayo KH, Hackeng TM, Weber C. Chemokine interactome mapping enables tailored intervention in acute and chronic inflammation. Sci Transl Med 2017; 9(384). https://www.ncbi.nlm.nih.gov/pubmed/28381538
- Weber C, Badimon L, Mach F, van der Vorst EPC. Therapeutic strategies for atherosclerosis and atherothrombosis: Past, present and future. Thromb Haemost 2017; 117(7): 1258-64. https://www.ncbi.nlm.nih.gov/pubmed/28594053
- Weber C, Lip GY. Editors' Choice 2016 papers in Thrombosis and Haemostasis. Thromb Haemost 2017; 117(1): 204-6. https://www.ncbi.nlm.nih.gov/pubmed/28066852
- Weber C, von Hundelshausen P. CANTOS Trial Validates the Inflammatory Pathogenesis of Atherosclerosis: Setting the Stage for a New Chapter in Therapeutic Targeting. Circ Res 2017; 121(10): 1119-21. https://www.ncbi.nlm.nih.gov/pubmed/29074528
- Winkels H, Meiler S, Lievens D, Engel D, Spitz C, Burger C, Beckers L, Dandl A, Reim S, Ahmadsei M, Hartwig H, Holdt LM, Hristov M, Megens RTA, Schmitt MM, Biessen EA, Borst J, Faussner A, Weber C, Lutgens E, Gerdes N. CD27 co-stimulation increases the abundance of regulatory T cells and reduces atherosclerosis in hyperlipidaemic mice. Eur Heart J 2017; 38(48): 3590-9. https://www.ncbi.nlm.nih.gov/pubmed/29045618
- Wolf D, Bukosza N, Engel D, Poggi M, Jehle F, Anto Michel N, Chen YC, Colberg C, Hoppe N, Dufner B, Boon L, Blankenbach H, Hilgendorf I, von Zur Muhlen C, Reinohl J, Sommer B, Marchini T, Febbraio MA, Weber C, Bode C, Peter K, Lutgens E, Zirlik A. Inflammation, but not recruitment, of adipose tissue macrophages requires signalling through Mac-1 (CD11b/CD18) in diet-induced obesity (DIO). Thromb Haemost 2017; 117(2): 325-38. https://www.ncbi.nlm.nih.gov/pubmed/27853810
- Wu Z, Rademakers T, Kiessling F, Vogt M, Westein E, Weber C, Megens RTA, van Zandvoort M. Multi-photon microscopy in cardiovascular research. Methods 2017; 130: 79-89. https://www.ncbi.nlm.nih.gov/pubmed/28434997
- Xu Y, Wang Y, Yan S, Zhou Y, Yang Q, Pan Y, Zeng X, An X, Liu Z, Wang L, Xu J, Cao Y, Fulton DJ, Weintraub NL, Bagi Z, Hoda MN, Wang X, Li Q, Hong M, Jiang X, Boison D, Weber C, Wu C, Huo Y. Intracellular adenosine regulates epigenetic programming in endothelial cells to promote angiogenesis. EMBO Mol Med 2017; 9(9): 1263-78. https://www.ncbi.nlm.nih.gov/pubmed/28751580
- Yin C, Mohanta S, Maffia P, Habenicht AJ. Editorial: Tertiary Lymphoid Organs (TLOs): Powerhouses of Disease Immunity. Front Immunol 2017; 8: 228. https://www.ncbi.nlm.nih.gov/pubmed/28321222
- Zahedi F, Nazari-Jahantigh M, Zhou Z, Subramanian P, Wei Y, Grommes J, Offermanns S, Steffens S, Weber C, Schober A. Dicer generates a regulatory microRNA network in smooth muscle cells that limits neointima formation during vascular repair. Cell Mol Life Sci 2017; 74(2): 359-72. https://www.ncbi.nlm.nih.gov/pubmed/27622243
- Zhao Z, Vajen T, Karshovska E, Dickhout A, Schmitt MM, Megens RTA, von Hundelshausen P, Koeppel TA, Hackeng TM, Weber C, Koenen RR. Deletion of junctional adhesion molecule A from platelets increases early-stage neointima formation after wire injury in hyperlipidemic mice. J Cell Mol Med 2017; 21(8): 1523-31. https://www.ncbi.nlm.nih.gov/pubmed/28211187
- Zhu M, Wei Y, Geissler C, Abschlag K, Corbalan Campos J, Hristov M, Mollmann J, Lehrke M, Karshovska E, Schober A. Hyperlipidemia-Induced MicroRNA-155-5p Improves beta-Cell Function by Targeting Mafb. Diabetes 2017; 66(12): 3072-84. https://www.ncbi.nlm.nih.gov/pubmed/28970282
- Ziegler T, Kraus M, Husada W, Gesenhues F, Jiang Q, Pinkenburg O, Trenkwalder T, Laugwitz KL, le Noble F, Weber C, Kupatt C, Hinkel R. Steerable Induction of the Thymosin beta4/MRTF-A Pathway via AAV-Based Overexpression Induces Therapeutic Neovascularization. Hum Gene Ther 2017; 29(12): 1407-1415. https://www.ncbi.nlm.nih.gov/pubmed/28726522
- Alam A, Leoni G, Quiros M, Wu H, Desai C, Nishio H, Jones RM, Nusrat A, Neish AS. The microenvironment of injured murine gut elicits a local pro-restitutive microbiota. Nat Microbiol 2016; 1: 15021. https://www.ncbi.nlm.nih.gov/pubmed/27571978
- Braster Q, Silvestre Roig C, Hartwig H, Beckers L, den Toom M, Doring Y, Daemen MJ, Lutgens E, Soehnlein O. Inhibition of NET Release Fails to Reduce Adipose Tissue Inflammation in Mice. PLoS One 2016; 11(10): e0163922. https://www.ncbi.nlm.nih.gov/pubmed/27701440
- Braster Q, Silvestre-Roig C, Hartwig H, Kusters P, Aarts S, den Toom M, Gallo RL, Weber C, Lutgens E, Soehnlein O. Cathelicidin regulates myeloid cell accumulation in adipose tissue and promotes insulin resistance during obesity. Thromb Haemost 2016; 115(6): 1237-9. https://www.ncbi.nlm.nih.gov/pubmed/26939624
- Campa CC, Germena G, Ciraolo E, Copperi F, Sapienza A, Franco I, Ghigo A, Camporeale A, Di Savino A, Martini M, Perino A, Megens RT, Kurz AR, Scheiermann C, Sperandio M, Gamba A, Hirsch E. Rac signal adaptation controls neutrophil mobilization from the bone marrow. Sci Signal 2016; 9(459): ra124. https://www.ncbi.nlm.nih.gov/pubmed/27999173
- Chong SZ, Evrard M, Devi S, Chen J, Lim JY, See P, Zhang Y, Adrover JM, Lee B, Tan L, Li JL, Liong KH, Phua C, Balachander A, Boey A, Liebl D, Tan SM, Chan JK, Balabanian K, Harris JE, Bianchini M, Weber C, Duchene J, Lum J, Poidinger M, Chen Q, Renia L, Wang CI, Larbi A, Randolph GJ, Weninger W, Looney MR, Krummel MF, Biswas SK, Ginhoux F, Hidalgo A, Bachelerie F, Ng LG. CXCR4 identifies transitional bone marrow premonocytes that replenish the mature monocyte pool for peripheral responses. J Exp Med 2016; 213(11): 2293-314. https://www.ncbi.nlm.nih.gov/pubmed/27811056
- Chubanov V, Ferioli S, Wisnowsky A, Simmons DG, Leitzinger C, Einer C, Jonas W, Shymkiv Y, Bartsch H, Braun A, Akdogan B, Mittermeier L, Sytik L, Torben F, Jurinovic V, van der Vorst EPC, Weber C, Yildirim ÖA, Sotlar K, Schürmann A, Zierler S, Zischka H, Ryazanov AG, Gudermann T. Author response: Epithelial magnesium transport by TRPM6 is essential for prenatal development and adult survival. eLife Sciences Publications, Ltd 2016.
- Daugherty A, Hegele RA, Mackman N, Rader DJ, Schmidt AM, Weber C. Complying With the National Institutes of Health Guidelines and Principles for Rigor and Reproducibility: Refutations. Arterioscler Thromb Vasc Biol 2016; 36(7): 1303-4. https://www.ncbi.nlm.nih.gov/pubmed/27335467
- de Jong R, Leoni G, Drechsler M, Soehnlein O. The advantageous role of annexin A1 in cardiovascular disease. Cell Adh Migr 2017; 11(3): 261-74. https://www.ncbi.nlm.nih.gov/pubmed/27860536
- Deppe J, Popp T, Egea V, Steinritz D, Schmidt A, Thiermann H, Weber C, Ries C. Impairment of hypoxia-induced HIF-1alpha signaling in keratinocytes and fibroblasts by sulfur mustard is counteracted by a selective PHD-2 inhibitor. Arch Toxicol 2016; 90(5): 1141-50. https://www.ncbi.nlm.nih.gov/pubmed/26082309
- Deppe J, Steinritz D, Santovito D, Egea V, Schmidt A, Weber C, Ries C. Upregulation of miR-203 and miR-210 affect growth and differentiation of keratinocytes after exposure to sulfur mustard in normoxia and hypoxia. Toxicol Lett 2016; 244: 81-7. https://www.ncbi.nlm.nih.gov/pubmed/26383628
- Finan B, Clemmensen C, Zhu Z, Stemmer K, Gauthier K, Muller L, De Angelis M, Moreth K, Neff F, Perez-Tilve D, Fischer K, Lutter D, Sanchez-Garrido MA, Liu P, Tuckermann J, Malehmir M, Healy ME, Weber A, Heikenwalder M, Jastroch M, Kleinert M, Jall S, Brandt S, Flamant F, Schramm KW, Biebermann H, Doring Y, Weber C, Habegger KM, Keuper M, Gelfanov V, Liu F, Kohrle J, Rozman J, Fuchs H, Gailus-Durner V, Hrabe de Angelis M, Hofmann SM, Yang B, Tschop MH, DiMarchi R, Muller TD. Chemical Hybridization of Glucagon and Thyroid Hormone Optimizes Therapeutic Impact for Metabolic Disease. Cell 2016; 167(3): 843-57 e14. https://www.ncbi.nlm.nih.gov/pubmed/27720451
- Gamrekelashvili J, Giagnorio R, Jussofie J, Soehnlein O, Duchene J, Briseno CG, Ramasamy SK, Krishnasamy K, Limbourg A, Kapanadze T, Ishifune C, Hinkel R, Radtke F, Strobl LJ, Zimber-Strobl U, Napp LC, Bauersachs J, Haller H, Yasutomo K, Kupatt C, Murphy KM, Adams RH, Weber C, Limbourg FP. Regulation of monocyte cell fate by blood vessels mediated by Notch signalling. Nat Commun 2016; 7: 12597. https://www.ncbi.nlm.nih.gov/pubmed/27576369
- Gerdes N, Seijkens T, Lievens D, Kuijpers MJ, Winkels H, Projahn D, Hartwig H, Beckers L, Megens RT, Boon L, Noelle RJ, Soehnlein O, Heemskerk JW, Weber C, Lutgens E. Platelet CD40 Exacerbates Atherosclerosis by Transcellular Activation of Endothelial Cells and Leukocytes. Arterioscler Thromb Vasc Biol 2016; 36(3): 482-90. https://www.ncbi.nlm.nih.gov/pubmed/26821950
- Hartmann D, Fiedler J, Sonnenschein K, Just A, Pfanne A, Zimmer K, Remke J, Foinquinos A, Butzlaff M, Schimmel K, Maegdefessel L, Hilfiker-Kleiner D, Lachmann N, Schober A, Froese N, Heineke J, Bauersachs J, Batkai S, Thum T. MicroRNA-Based Therapy of GATA2-Deficient Vascular Disease. Circulation 2016; 134(24): 1973-90. https://www.ncbi.nlm.nih.gov/pubmed/27780851
- Hartmann P, Zhou Z, Natarelli L, Wei Y, Nazari-Jahantigh M, Zhu M, Grommes J, Steffens S, Weber C, Schober A. Endothelial Dicer promotes atherosclerosis and vascular inflammation by miRNA-103-mediated suppression of KLF4. Nat Commun 2016; 7: 10521. https://www.ncbi.nlm.nih.gov/pubmed/26837267
- Hibender S, Franken R, van Roomen C, Ter Braake A, van der Made I, Schermer EE, Gunst Q, van den Hoff MJ, Lutgens E, Pinto YM, Groenink M, Zwinderman AH, Mulder BJ, de Vries CJ, de Waard V. Resveratrol Inhibits Aortic Root Dilatation in the Fbn1C1039G/+ Marfan Mouse Model. Arterioscler Thromb Vasc Biol 2016; 36(8): 1618-26. https://www.ncbi.nlm.nih.gov/pubmed/27283746
- Hu D, Yin C, Mohanta SK, Weber C, Habenicht AJ. Preparation of Single Cell Suspensions from Mouse Aorta. Bio Protoc 2016; 6(11): e1832. https://www.ncbi.nlm.nih.gov/pubmed/27335895
- Jamasbi J, Megens RT, Bianchini M, Uhland K, Munch G, Ungerer M, Sherman S, Faussner A, Brandl R, John C, Buchner J, Weber C, Lorenz R, Elia N, Siess W. Cross-Linking GPVI-Fc by Anti-Fc Antibodies Potentiates Its Inhibition of Atherosclerotic Plaque- and Collagen-Induced Platelet Activation. JACC Basic Transl Sci 2016; 1(3): 131-42. https://www.ncbi.nlm.nih.gov/pubmed/27766315
- Jansen MF, Hollander MR, van Royen N, Horrevoets AJ, Lutgens E. CD40 in coronary artery disease: a matter of macrophages? Basic Res Cardiol 2016; 111(4): 38. https://www.ncbi.nlm.nih.gov/pubmed/27146510
- Leiva M, Hidalgo A. Bidirectional dialog in the haematopoietic niche. Cell Cycle 2016; 15(8): 1027-8. https://www.ncbi.nlm.nih.gov/pubmed/27097370
- Leiva M, Quintana JA, Ligos JM, Hidalgo A. Haematopoietic ESL-1 enables stem cell proliferation in the bone marrow by limiting TGFbeta availability. Nat Commun 2016; 7: 10222. https://www.ncbi.nlm.nih.gov/pubmed/26742601
- Li J, McArdle S, Gholami A, Kimura T, Wolf D, Gerhardt T, Miller J, Weber C, Ley K. CCR5+T-bet+FoxP3+ Effector CD4 T Cells Drive Atherosclerosis. Circ Res 2016; 118(10): 1540-52. https://www.ncbi.nlm.nih.gov/pubmed/27021296
- Lip GYH, Weber C. May your New Year be happy and prosperous with “Thrombosis and Haemostasis”. Thrombosis and Haemostasis 2016; 115(01): 1-2. http://dx.doi.org/10.1160/th15-11-0912
- Mahl C, Egea V, Megens RT, Pitsch T, Santovito D, Weber C, Ries C. RECK (reversion-inducing cysteine-rich protein with Kazal motifs) regulates migration, differentiation and Wnt/beta-catenin signaling in human mesenchymal stem cells. Cell Mol Life Sci 2016; 73(7): 1489-501. https://www.ncbi.nlm.nih.gov/pubmed/26459448
- Martinez-Moreno M, Leiva M, Aguilera-Montilla N, Sevilla-Movilla S, Isern de Val S, Arellano-Sanchez N, Gutierrez NC, Maldonado R, Martinez-Lopez J, Buno I, Garcia-Marco JA, Sanchez-Mateos P, Hidalgo A, Garcia-Pardo A, Teixido J. In vivo adhesion of malignant B cells to bone marrow microvasculature is regulated by alpha4beta1 cytoplasmic-binding proteins. Leukemia 2016; 30(4): 861-72. https://www.ncbi.nlm.nih.gov/pubmed/26658839
- Meiler S, Smeets E, Winkels H, Shami A, Pascutti MF, Nolte MA, Beckers L, Weber C, Gerdes N, Lutgens E. Constitutive GITR Activation Reduces Atherosclerosis by Promoting Regulatory CD4+ T-Cell Responses-Brief Report. Arterioscler Thromb Vasc Biol 2016; 36(9): 1748-52. https://www.ncbi.nlm.nih.gov/pubmed/27444204
- Mohanta S, Yin C, Weber C, Hu D, Habenicht AJ. Aorta Atherosclerosis Lesion Analysis in Hyperlipidemic Mice. Bio Protoc 2016; 6(11): e1833. https://www.ncbi.nlm.nih.gov/pubmed/27366759
- Muhlstedt S, Ghadge SK, Duchene J, Qadri F, Jarve A, Vilianovich L, Popova E, Pohlmann A, Niendorf T, Boye P, Ozcelik C, Bader M. Cardiomyocyte-derived CXCL12 is not involved in cardiogenesis but plays a crucial role in myocardial infarction. J Mol Med (Berl) 2016; 94(9): 1005-14. https://www.ncbi.nlm.nih.gov/pubmed/27251706
- Nus M, Martinez-Poveda B, MacGrogan D, Chevre R, D'Amato G, Sbroggio M, Rodriguez C, Martinez-Gonzalez J, Andres V, Hidalgo A, de la Pompa JL. Endothelial Jag1-RBPJ signalling promotes inflammatory leucocyte recruitment and atherosclerosis. Cardiovasc Res 2016; 112(2): 568-80. https://www.ncbi.nlm.nih.gov/pubmed/27496872
- Ortega-Gomez A, Salvermoser M, Rossaint J, Pick R, Brauner J, Lemnitzer P, Tilgner J, de Jong RJ, Megens RT, Jamasbi J, Doring Y, Pham CT, Scheiermann C, Siess W, Drechsler M, Weber C, Grommes J, Zarbock A, Walzog B, Soehnlein O. Cathepsin G Controls Arterial But Not Venular Myeloid Cell Recruitment. Circulation 2016; 134(16): 1176-88. https://www.ncbi.nlm.nih.gov/pubmed/27660294
- Petzold T, Thienel M, Konrad I, Schubert I, Regenauer R, Hoppe B, Lorenz M, Eckart A, Chandraratne S, Lennerz C, Kolb C, Braun D, Jamasbi J, Brandl R, Braun S, Siess W, Schulz C, Massberg S. Oral thrombin inhibitor aggravates platelet adhesion and aggregation during arterial thrombosis. Sci Transl Med 2016; 8(367): 367ra168. https://www.ncbi.nlm.nih.gov/pubmed/27903864
- Rajasekaran D, Groning S, Schmitz C, Zierow S, Drucker N, Bakou M, Kohl K, Mertens A, Lue H, Weber C, Xiao A, Luker G, Kapurniotu A, Lolis E, Bernhagen J. Macrophage Migration Inhibitory Factor-CXCR4 Receptor Interactions: EVIDENCE FOR PARTIAL ALLOSTERIC AGONISM IN COMPARISON WITH CXCL12 CHEMOKINE. J Biol Chem 2016; 291(30): 15881-95. https://www.ncbi.nlm.nih.gov/pubmed/27226569
- Santovito D, Egea V, Weber C. Small but smart: MicroRNAs orchestrate atherosclerosis development and progression. Biochim Biophys Acta 2016; 1861(12 Pt B): 2075-86. https://www.ncbi.nlm.nih.gov/pubmed/26738655
- Schaftenaar F, Frodermann V, Kuiper J, Lutgens E. Atherosclerosis: the interplay between lipids and immune cells. Curr Opin Lipidol 2016; 27(3): 209-15. https://www.ncbi.nlm.nih.gov/pubmed/27031276
- Schloss MJ, Horckmans M, Nitz K, Duchene J, Drechsler M, Bidzhekov K, Scheiermann C, Weber C, Soehnlein O, Steffens S. The time-of-day of myocardial infarction onset affects healing through oscillations in cardiac neutrophil recruitment. EMBO Mol Med 2016; 8(8): 937-48. https://www.ncbi.nlm.nih.gov/pubmed/27226028
- Schmohl J, Santovito D, Guenther T, Sutanto W, Kroell T, Salih H, Pitsch T, Egea V, Weber C, Schmetzer H, Ries C. Expression of surface-associated 82kDa-proMMP-9 in primary acute leukemia blast cells inversely correlates with patients' risk. Exp Hematol 2016; 44(5): 358-62 e5. https://www.ncbi.nlm.nih.gov/pubmed/26845021
- Schober A, Weber C. Mechanisms of MicroRNAs in Atherosclerosis. Annu Rev Pathol 2016; 11(1): 583-616. https://www.ncbi.nlm.nih.gov/pubmed/27193456
- Silvestre-Roig C, Hidalgo A, Soehnlein O. Neutrophil heterogeneity: implications for homeostasis and pathogenesis. Blood 2016; 127(18): 2173-81. https://www.ncbi.nlm.nih.gov/pubmed/27002116
- Simsekyilmaz S, Liehn EA, Weinandy S, Schreiber F, Megens RT, Theelen W, Smeets R, Jockenhovel S, Gries T, Moller M, Klee D, Weber C, Zernecke A. Targeting In-Stent-Stenosis with RGD- and CXCL1-Coated Mini-Stents in Mice. PLoS One 2016; 11(5): e0155829. https://www.ncbi.nlm.nih.gov/pubmed/27192172
- Soehnlein O. Monocytes Chat With Atherosclerotic Lesions. Arterioscler Thromb Vasc Biol 2016; 36(9): 1720-1. https://www.ncbi.nlm.nih.gov/pubmed/27559145
- Spitz C, Winkels H, Burger C, Weber C, Lutgens E, Hansson GK, Gerdes N. Regulatory T cells in atherosclerosis: critical immune regulatory function and therapeutic potential. Cell Mol Life Sci 2016; 73(5): 901-22. https://www.ncbi.nlm.nih.gov/pubmed/26518635
- Spronck B, Megens RT, Reesink KD, Delhaas T. A method for three-dimensional quantification of vascular smooth muscle orientation: application in viable murine carotid arteries. Biomech Model Mechanobiol 2016; 15(2): 419-32. https://www.ncbi.nlm.nih.gov/pubmed/26174758
- Srikakulapu P, Hu D, Yin C, Mohanta SK, Bontha SV, Peng L, Beer M, Weber C, McNamara CA, Grassia G, Maffia P, Manz RA, Habenicht AJ. Artery Tertiary Lymphoid Organs Control Multilayered Territorialized Atherosclerosis B-Cell Responses in Aged ApoE-/- Mice. Arterioscler Thromb Vasc Biol 2016; 36(6): 1174-85. https://www.ncbi.nlm.nih.gov/pubmed/27102965
- Steffens S. M1 signature mediators in atheroma-derived single cell secretome of symptomatic plaques. Thromb Haemost 2016; 115(5): 871. https://www.ncbi.nlm.nih.gov/pubmed/27052888
- Tilgner J, von Trotha KT, Gombert A, Jacobs MJ, Drechsler M, Doring Y, Soehnlein O, Grommes J. Aspirin, but Not Tirofiban Displays Protective Effects in Endotoxin Induced Lung Injury. PLoS One 2016; 11(9): e0161218. https://www.ncbi.nlm.nih.gov/pubmed/27583400
- van Dam AD, Bekkering S, Crasborn M, van Beek L, van den Berg SM, Vrieling F, Joosten SA, van Harmelen V, de Winther MPJ, Lutjohann D, Lutgens E, Boon MR, Riksen NP, Rensen PCN, Berbee JFP. BCG lowers plasma cholesterol levels and delays atherosclerotic lesion progression in mice. Atherosclerosis 2016; 251: 6-14. https://www.ncbi.nlm.nih.gov/pubmed/27232458
- Viola J, Soehnlein O. Atherosclerosis - A matter of unresolved inflammation. Semin Immunol 2015; 27(3): 184-93. https://www.ncbi.nlm.nih.gov/pubmed/25865626
- Viola JR, Lemnitzer P, Jansen Y, Csaba G, Winter C, Neideck C, Silvestre-Roig C, Dittmar G, Doring Y, Drechsler M, Weber C, Zimmer R, Cenac N, Soehnlein O. Resolving Lipid Mediators Maresin 1 and Resolvin D2 Prevent Atheroprogression in Mice. Circ Res 2016; 119(9): 1030-8. https://www.ncbi.nlm.nih.gov/pubmed/27531933
- Weber C, Doring Y, Noels H. Potential cell-specific functions of CXCR4 in atherosclerosis. Hamostaseologie 2016; 36(2): 97-102. https://www.ncbi.nlm.nih.gov/pubmed/25586789
- Weber C, Shantsila E, Hristov M, Caligiuri G, Guzik T, Heine GH, Hoefer IE, Monaco C, Peter K, Rainger E, Siegbahn A, Steffens S, Wojta J, Lip GY. Role and analysis of monocyte subsets in cardiovascular disease. Joint consensus document of the European Society of Cardiology (ESC) Working Groups "Atherosclerosis & Vascular Biology" and "Thrombosis". Thromb Haemost 2016; 116(4): 626-37. https://www.ncbi.nlm.nih.gov/pubmed/27412877
- Wei Y, Schober A. MicroRNA regulation of macrophages in human pathologies. Cell Mol Life Sci 2016; 73(18): 3473-95. https://www.ncbi.nlm.nih.gov/pubmed/27137182
- Wichapong K, Alard JE, Ortega-Gomez A, Weber C, Hackeng TM, Soehnlein O, Nicolaes GA. Structure-Based Design of Peptidic Inhibitors of the Interaction between CC Chemokine Ligand 5 (CCL5) and Human Neutrophil Peptides 1 (HNP1). J Med Chem 2016; 59(9): 4289-301. https://www.ncbi.nlm.nih.gov/pubmed/26871718
- Yin C, Mohanta SK, Srikakulapu P, Weber C, Habenicht AJ. Artery Tertiary Lymphoid Organs: Powerhouses of Atherosclerosis Immunity. Front Immunol 2016; 7: 387. https://www.ncbi.nlm.nih.gov/pubmed/27777573
- Ziegler T, Horstkotte M, Lange P, Ng J, Bongiovanni D, Hinkel R, Laugwitz KL, Sperandio M, Horstkotte J, Kupatt C. Endothelial RAGE exacerbates acute postischaemic cardiac inflammation. Thromb Haemost 2016; 116(2): 300-8. https://www.ncbi.nlm.nih.gov/pubmed/27412300
- Ahmadsei M, Lievens D, Weber C, von Hundelshausen P, Gerdes N. Immune-mediated and lipid-mediated platelet function in atherosclerosis. Curr Opin Lipidol 2015; 26(5): 438-48. https://www.ncbi.nlm.nih.gov/pubmed/26270811
- Akhtar S, Hartmann P, Karshovska E, Rinderknecht FA, Subramanian P, Gremse F, Grommes J, Jacobs M, Kiessling F, Weber C, Steffens S, Schober A. Endothelial Hypoxia-Inducible Factor-1alpha Promotes Atherosclerosis and Monocyte Recruitment by Upregulating MicroRNA-19a. Hypertension 2015; 66(6): 1220-6. https://www.ncbi.nlm.nih.gov/pubmed/26483345
- Alampour-Rajabi S, El Bounkari O, Rot A, Muller-Newen G, Bachelerie F, Gawaz M, Weber C, Schober A, Bernhagen J. MIF interacts with CXCR7 to promote receptor internalization, ERK1/2 and ZAP-70 signaling, and lymphocyte chemotaxis. FASEB J 2015; 29(11): 4497-511. https://www.ncbi.nlm.nih.gov/pubmed/26139098
- Alard JE, Ortega-Gomez A, Wichapong K, Bongiovanni D, Horckmans M, Megens RT, Leoni G, Ferraro B, Rossaint J, Paulin N, Ng J, Ippel H, Suylen D, Hinkel R, Blanchet X, Gaillard F, D'Amico M, von Hundelshausen P, Zarbock A, Scheiermann C, Hackeng TM, Steffens S, Kupatt C, Nicolaes GA, Weber C, Soehnlein O. Recruitment of classical monocytes can be inhibited by disturbing heteromers of neutrophil HNP1 and platelet CCL5. Sci Transl Med 2015; 7(317): 317ra196. https://www.ncbi.nlm.nih.gov/pubmed/26659570
- Azghandi S, Prell C, van der Laan SW, Schneider M, Malik R, Berer K, Gerdes N, Pasterkamp G, Weber C, Haffner C, Dichgans M. Deficiency of the stroke relevant HDAC9 gene attenuates atherosclerosis in accord with allele-specific effects at 7p21.1. Stroke 2015; 46(1): 197-202. https://www.ncbi.nlm.nih.gov/pubmed/25388417
- Back M, Weber C, Lutgens E. Regulation of atherosclerotic plaque inflammation. J Intern Med 2015; 278(5): 462-82. https://www.ncbi.nlm.nih.gov/pubmed/25823439
- Bernlochner I, Goedel A, Plischke C, Schupke S, Haller B, Schulz C, Mayer K, Morath T, Braun S, Schunkert H, Siess W, Kastrati A, Laugwitz KL. Impact of immature platelets on platelet response to ticagrelor and prasugrel in patients with acute coronary syndrome. Eur Heart J 2015; 36(45): 3202-10. https://www.ncbi.nlm.nih.gov/pubmed/26216931
- Burger C, Weber C, Lutgens E, Gerdes N. Atherosclerosis: cell biology and lipoproteins-focus on CD40 signaling, PCSK9, and novel animal models. Curr Opin Lipidol 2015; 26(3): 245-6. https://www.ncbi.nlm.nih.gov/pubmed/25950709
- Curaj A, Wu Z, Fokong S, Liehn EA, Weber C, Burlacu A, Lammers T, van Zandvoort M, Kiessling F. Noninvasive molecular ultrasound monitoring of vessel healing after intravascular surgical procedures in a preclinical setup. Arterioscler Thromb Vasc Biol 2015; 35(6): 1366-73. https://www.ncbi.nlm.nih.gov/pubmed/25838431
- Doring Y. Not growth but death: GM-CSF/IL-23 axis drives atherosclerotic plaque vulnerability by enhancing macrophage and DC apoptosis. Circ Res 2015; 116(2): 222-4. https://www.ncbi.nlm.nih.gov/pubmed/25593270
- Doring Y, Drechsler M, Soehnlein O, Weber C. Neutrophils in atherosclerosis: from mice to man. Arterioscler Thromb Vasc Biol 2015; 35(2): 288-95. https://www.ncbi.nlm.nih.gov/pubmed/25147339
- Drechsler M, de Jong R, Rossaint J, Viola JR, Leoni G, Wang JM, Grommes J, Hinkel R, Kupatt C, Weber C, Doring Y, Zarbock A, Soehnlein O. Annexin A1 counteracts chemokine-induced arterial myeloid cell recruitment. Circ Res 2015; 116(5): 827-35. https://www.ncbi.nlm.nih.gov/pubmed/25520364
- Drechsler M, Duchene J, Soehnlein O. Chemokines control mobilization, recruitment, and fate of monocytes in atherosclerosis. Arterioscler Thromb Vasc Biol 2015; 35(5): 1050-5. https://www.ncbi.nlm.nih.gov/pubmed/25792446
- Duchene J, von Hundelshausen P. Platelet-derived chemokines in atherosclerosis. Hamostaseologie 2015; 35(2): 137-41. https://www.ncbi.nlm.nih.gov/pubmed/25592448
- Hartmann P, Schober A, Weber C. Chemokines and microRNAs in atherosclerosis. Cell Mol Life Sci 2015; 72(17): 3253-66. https://www.ncbi.nlm.nih.gov/pubmed/26001902
- Hartwig H, Silvestre Roig C, Daemen M, Lutgens E, Soehnlein O. Neutrophils in atherosclerosis. A brief overview. Hamostaseologie 2015; 35(2): 121-7. https://www.ncbi.nlm.nih.gov/pubmed/25385255
- Hartwig H, Silvestre-Roig C, Hendrikse J, Beckers L, Paulin N, Van der Heiden K, Braster Q, Drechsler M, Daemen MJ, Lutgens E, Soehnlein O. Atherosclerotic Plaque Destabilization in Mice: A Comparative Study. PLoS One 2015; 10(10): e0141019. https://www.ncbi.nlm.nih.gov/pubmed/26492161
- Hinkel R, Lange P, Petersen B, Gottlieb E, Ng JK, Finger S, Horstkotte J, Lee S, Thormann M, Knorr M, El-Aouni C, Boekstegers P, Reichart B, Wenzel P, Niemann H, Kupatt C. Heme Oxygenase-1 Gene Therapy Provides Cardioprotection Via Control of Post-Ischemic Inflammation: An Experimental Study in a Pre-Clinical Pig Model. J Am Coll Cardiol 2015; 66(2): 154-65. https://www.ncbi.nlm.nih.gov/pubmed/26160631
- Hoefer IE, Steffens S, Ala-Korpela M, Back M, Badimon L, Bochaton-Piallat ML, Boulanger CM, Caligiuri G, Dimmeler S, Egido J, Evans PC, Guzik T, Kwak BR, Landmesser U, Mayr M, Monaco C, Pasterkamp G, Tunon J, Weber C, Atherosclerosis ESCWG, Vascular B. Novel methodologies for biomarker discovery in atherosclerosis. Eur Heart J 2015; 36(39): 2635-42. https://www.ncbi.nlm.nih.gov/pubmed/26049157
- Hristov M, Weber C. Myocardial infarction and inflammation: lost in the biomarker labyrinth. Circ Res 2015; 116(5): 781-3. https://www.ncbi.nlm.nih.gov/pubmed/25722440
- Hu D, Mohanta SK, Yin C, Peng L, Ma Z, Srikakulapu P, Grassia G, MacRitchie N, Dever G, Gordon P, Burton FL, Ialenti A, Sabir SR, McInnes IB, Brewer JM, Garside P, Weber C, Lehmann T, Teupser D, Habenicht L, Beer M, Grabner R, Maffia P, Weih F, Habenicht AJ. Artery Tertiary Lymphoid Organs Control Aorta Immunity and Protect against Atherosclerosis via Vascular Smooth Muscle Cell Lymphotoxin beta Receptors. Immunity 2015; 42(6): 1100-15. https://www.ncbi.nlm.nih.gov/pubmed/26084025
- Ippel H, Miller MC, Berbis MA, Suylen D, Andre S, Hackeng TM, Canada FJ, Weber C, Gabius HJ, Jimenez-Barbero J, Mayo KH. (1)H, (13)C, and (15)N backbone and side-chain chemical shift assignments for the 36 proline-containing, full length 29 kDa human chimera-type galectin-3. Biomol NMR Assign 2015; 9(1): 59-63. https://www.ncbi.nlm.nih.gov/pubmed/24504927
- Jamasbi J, Megens RT, Bianchini M, Munch G, Ungerer M, Faussner A, Sherman S, Walker A, Goyal P, Jung S, Brandl R, Weber C, Lorenz R, Farndale R, Elia N, Siess W. Differential Inhibition of Human Atherosclerotic Plaque-Induced Platelet Activation by Dimeric GPVI-Fc and Anti-GPVI Antibodies: Functional and Imaging Studies. J Am Coll Cardiol 2015; 65(22): 2404-15. https://www.ncbi.nlm.nih.gov/pubmed/26046734
- Karshovska E, Zhao Z, Blanchet X, Schmitt MM, Bidzhekov K, Soehnlein O, von Hundelshausen P, Mattheij NJ, Cosemans JM, Megens RT, Koeppel TA, Schober A, Hackeng TM, Weber C, Koenen RR. Hyperreactivity of junctional adhesion molecule A-deficient platelets accelerates atherosclerosis in hyperlipidemic mice. Circ Res 2015; 116(4): 587-99. https://www.ncbi.nlm.nih.gov/pubmed/25472975
- Klapproth S, Sperandio M, Pinheiro EM, Prunster M, Soehnlein O, Gertler FB, Fassler R, Moser M. Loss of the Rap1 effector RIAM results in leukocyte adhesion deficiency due to impaired beta2 integrin function in mice. Blood 2015; 126(25): 2704-12. https://www.ncbi.nlm.nih.gov/pubmed/26337492
- Kornmann LM, Zernecke A, Curfs DM, Janssen BJ, Weber C, de Winther MP, Reneman RS, Hoeks AP, Reesink KD. Echogenic perfluorohexane-loaded macrophages adhere in vivo to activated vascular endothelium in mice, an explorative study. Cardiovasc Ultrasound 2015; 13: 1. https://www.ncbi.nlm.nih.gov/pubmed/25567641
- Kuijpers MJ, Mattheij NJ, Cipolla L, van Geffen JP, Lawrence T, Donners MM, Boon L, Lievens D, Torti M, Noels H, Gerdes N, Cosemans JM, Lutgens E, Heemskerk JW. Platelet CD40L Modulates Thrombus Growth Via Phosphatidylinositol 3-Kinase beta, and Not Via CD40 and IkappaB Kinase alpha. Arterioscler Thromb Vasc Biol 2015; 35(6): 1374-81. https://www.ncbi.nlm.nih.gov/pubmed/25908768
- Kusters PJH, Lutgens E. Cytokines and Immune Responses in Murine Atherosclerosis. In: Methods in Molecular Biology. Springer New York 2015; pp. 17-40.
- Legein B, Janssen EM, Theelen TL, Gijbels MJ, Walraven J, Klarquist JS, Hennies CM, Wouters K, Seijkens TT, Wijnands E, Sluimer JC, Lutgens E, Zenke M, Hildner K, Biessen EA, Temmerman L. Ablation of CD8alpha(+) dendritic cell mediated cross-presentation does not impact atherosclerosis in hyperlipidemic mice. Sci Rep 2015; 5: 15414. https://www.ncbi.nlm.nih.gov/pubmed/26486587
- Leoni G, Neumann PA, Kamaly N, Quiros M, Nishio H, Jones HR, Sumagin R, Hilgarth RS, Alam A, Fredman G, Argyris I, Rijcken E, Kusters D, Reutelingsperger C, Perretti M, Parkos CA, Farokhzad OC, Neish AS, Nusrat A. Annexin A1-containing extracellular vesicles and polymeric nanoparticles promote epithelial wound repair. J Clin Invest 2015; 125(3): 1215-27. https://www.ncbi.nlm.nih.gov/pubmed/25664854
- Leoni G, Neumann PA, Sumagin R, Denning TL, Nusrat A. Wound repair: role of immune-epithelial interactions. Mucosal Immunol 2015; 8(5): 959-68. https://www.ncbi.nlm.nih.gov/pubmed/26174765
- Lichtenauer M, Franz M, Fritzenwanger M, Figulla HR, Gerdes N, Jung C. Elevated plasma levels of interleukin-12p40 and interleukin-16 in overweight adolescents. Biomed Res Int 2015; 2015: 940910. https://www.ncbi.nlm.nih.gov/pubmed/25710036
- Lip GY, Weber C. A happy new year from Thrombosis and Haemostasis. A 5 year reflection from the editorial team. Thromb Haemost 2015; 113(1): 1-2. https://www.ncbi.nlm.nih.gov/pubmed/25567473
- Lundeberg E, Van Der Does AM, Kenne E, Soehnlein O, Lindbom L. Assessing large-vessel endothelial permeability using near-infrared fluorescence imaging--brief report. Arterioscler Thromb Vasc Biol 2015; 35(4): 783-6. https://www.ncbi.nlm.nih.gov/pubmed/25675996
- Mandl M, Drechsler M, Jansen Y, Neideck C, Noels H, Faussner A, Soehnlein O, Weber C, Doring Y. Evaluation of the BDCA2-DTR Transgenic Mouse Model in Chronic and Acute Inflammation. PLoS One 2015; 10(8): e0134176. https://www.ncbi.nlm.nih.gov/pubmed/26252890
- Mandolini C, Santovito D, Marcantonio P, Buttitta F, Bucci M, Ucchino S, Mezzetti A, Cipollone F. Identification of microRNAs 758 and 33b as potential modulators of ABCA1 expression in human atherosclerotic plaques. Nutr Metab Cardiovasc Dis 2015; 25(2): 202-9. https://www.ncbi.nlm.nih.gov/pubmed/25445880
- Medina I, Cougoule C, Drechsler M, Bermudez B, Koenen RR, Sluimer J, Wolfs I, Doring Y, Herias V, Gijbels M, Bot I, de Jager S, Weber C, Cleutjens J, van Berkel TJC, Sikkink KJ, Mocsai A, Maridonneau-Parini I, Soehnlein O, Biessen EAL. Hck/Fgr Kinase Deficiency Reduces Plaque Growth and Stability by Blunting Monocyte Recruitment and Intraplaque Motility. Circulation 2015; 132(6): 490-501. https://www.ncbi.nlm.nih.gov/pubmed/26068045
- Megens RT, Bianchini M, Schmitt MM, Weber C. Optical imaging innovations for atherosclerosis research: multiphoton microscopy and optical nanoscopy. Arterioscler Thromb Vasc Biol 2015; 35(6): 1339-46. https://www.ncbi.nlm.nih.gov/pubmed/25908769
- Megens RTA, Soehnlein O. Intravital Microscopy for Atherosclerosis Research. In: Methods in Molecular Biology. Springer New York 2015; pp. 41-60.
- Molica F, Morel S, Kwak BR, Rohner-Jeanrenaud F, Steffens S. Adipokines at the crossroad between obesity and cardiovascular disease. Thromb Haemost 2015; 113(3): 553-66. https://www.ncbi.nlm.nih.gov/pubmed/25338625
- Natarelli L, Schober A. MicroRNAs and the response to injury in atherosclerosis. Hamostaseologie 2015; 35(2): 142-50. https://www.ncbi.nlm.nih.gov/pubmed/25612846
- Nazari-Jahantigh M, Egea V, Schober A, Weber C. MicroRNA-specific regulatory mechanisms in atherosclerosis. J Mol Cell Cardiol 2015; 89(Pt A): 35-41. https://www.ncbi.nlm.nih.gov/pubmed/25450610
- Njock MS, Cheng HS, Dang LT, Nazari-Jahantigh M, Lau AC, Boudreau E, Roufaiel M, Cybulsky MI, Schober A, Fish JE. Endothelial cells suppress monocyte activation through secretion of extracellular vesicles containing antiinflammatory microRNAs. Blood 2015; 125(20): 3202-12. https://www.ncbi.nlm.nih.gov/pubmed/25838349
- Pawig L, Klasen C, Weber C, Bernhagen J, Noels H. Diversity and Inter-Connections in the CXCR4 Chemokine Receptor/Ligand Family: Molecular Perspectives. Front Immunol 2015; 6: 429. https://www.ncbi.nlm.nih.gov/pubmed/26347749
- Renz M, Otten C, Faurobert E, Rudolph F, Zhu Y, Boulday G, Duchene J, Mickoleit M, Dietrich AC, Ramspacher C, Steed E, Manet-Dupe S, Benz A, Hassel D, Vermot J, Huisken J, Tournier-Lasserve E, Felbor U, Sure U, Albiges-Rizo C, Abdelilah-Seyfried S. Regulation of beta1 integrin-Klf2-mediated angiogenesis by CCM proteins. Dev Cell 2015; 32(2): 181-90. https://www.ncbi.nlm.nih.gov/pubmed/25625207
- Santovito D, Egea V, Weber C. DNA methylation and epigenetics: exploring the terra incognita of the atherosclerotic landscape. Eur Heart J 2015; 36(16): 956-8. https://www.ncbi.nlm.nih.gov/pubmed/25527822
- Santovito D, Weber C. Fibronectin extradomain A: balancing atherosclerotic plaque burden and stability. Thromb Haemost 2015; 114(1): 4. https://www.ncbi.nlm.nih.gov/pubmed/26062571
- Schober A, Nazari-Jahantigh M, Weber C. MicroRNA-mediated mechanisms of the cellular stress response in atherosclerosis. Nat Rev Cardiol 2015; 12(6): 361-74. https://www.ncbi.nlm.nih.gov/pubmed/25855604
- Selle J, Asare Y, Kohncke J, Alampour-Rajabi S, Shagdarsuren G, Klos A, Weber C, Jankowski J, Shagdarsuren E. Atheroprotective role of C5ar2 deficiency in apolipoprotein E-deficient mice. Thromb Haemost 2015; 114(4): 848-58. https://www.ncbi.nlm.nih.gov/pubmed/26084965
- Soehnlein O. (Re)solving atherosclerosis. Sci Transl Med 2015; 7(275): 275fs7. https://www.ncbi.nlm.nih.gov/pubmed/25695998
- Soehnlein O, Ortega-Gomez A, Doring Y, Weber C. Neutrophil-macrophage interplay in atherosclerosis: protease-mediated cytokine processing versus NET release. Thromb Haemost 2015; 114(4): 866-7. https://www.ncbi.nlm.nih.gov/pubmed/26310276
- Steffens S, Pacher P. The activated endocannabinoid system in atherosclerosis: driving force or protective mechanism? Curr Drug Targets 2015; 16(4): 334-41. https://www.ncbi.nlm.nih.gov/pubmed/25469884
- Stoppe C, Rex S, Goetzenich A, Kraemer S, Emontzpohl C, Soppert J, Averdunk L, Sun Y, Rossaint R, Lue H, Huang C, Song Y, Pantouris G, Lolis E, Leng L, Schulte W, Bucala R, Weber C, Bernhagen J. Interaction of MIF Family Proteins in Myocardial Ischemia/Reperfusion Damage and Their Influence on Clinical Outcome of Cardiac Surgery Patients. Antioxid Redox Signal 2015; 23(11): 865-79. https://www.ncbi.nlm.nih.gov/pubmed/26234719
- van Dam AD, Nahon KJ, Kooijman S, van den Berg SM, Kanhai AA, Kikuchi T, Heemskerk MM, van Harmelen V, Lombes M, van den Hoek AM, de Winther MP, Lutgens E, Guigas B, Rensen PC, Boon MR. Salsalate activates brown adipose tissue in mice. Diabetes 2015; 64(5): 1544-54. https://www.ncbi.nlm.nih.gov/pubmed/25475439
- van den Berg SM, Seijkens TT, Kusters PJ, Zarzycka B, Beckers L, den Toom M, Gijbels MJ, Chatzigeorgiou A, Weber C, de Winther MP, Chavakis T, Nicolaes GA, Lutgens E. Blocking CD40-TRAF6 interactions by small-molecule inhibitor 6860766 ameliorates the complications of diet-induced obesity in mice. Int J Obes (Lond) 2015; 39(5): 782-90. https://www.ncbi.nlm.nih.gov/pubmed/25394307
- van der Vorst EP, Doring Y, Weber C. Chemokines and their receptors in Atherosclerosis. J Mol Med (Berl) 2015; 93(9): 963-71. https://www.ncbi.nlm.nih.gov/pubmed/26175090
- van der Vorst EP, Doring Y, Weber C. MIF and CXCL12 in Cardiovascular Diseases: Functional Differences and Similarities. Front Immunol 2015; 6: 373. https://www.ncbi.nlm.nih.gov/pubmed/26257740
- van der Vorst EP, Doring Y, Weber C. Chemokines. Arterioscler Thromb Vasc Biol 2015; 35(11): e52-6. https://www.ncbi.nlm.nih.gov/pubmed/26490276
- Viola J, Soehnlein O. Atherosclerosis - A matter of unresolved inflammation. Semin Immunol 2015; 27(3): 184-93. https://www.ncbi.nlm.nih.gov/pubmed/25865626
- von Hundelshausen P, Oexle K, Bidzhekov K, Schmitt MM, Hristov M, Blanchet X, Kaemmerer H, Matyas G, Meitinger T, Weber C. Recurrent spontaneous coronary dissections in a patient with a de novo fibrillin-1 mutation without Marfan syndrome. Thromb Haemost 2015; 113(3): 668-70. https://www.ncbi.nlm.nih.gov/pubmed/25519456
- Wang J, Sun C, Gerdes N, Liu C, Liao M, Liu J, Shi MA, He A, Zhou Y, Sukhova GK, Chen H, Cheng XW, Kuzuya M, Murohara T, Zhang J, Cheng X, Jiang M, Shull GE, Rogers S, Yang CL, Ke Q, Jelen S, Bindels R, Ellison DH, Jarolim P, Libby P, Shi GP. Interleukin 18 function in atherosclerosis is mediated by the interleukin 18 receptor and the Na-Cl co-transporter. Nat Med 2015; 21(7): 820-6. https://www.ncbi.nlm.nih.gov/pubmed/26099046
- Weber C, Hristov M. Atherogenesis and inflammation. From cellular mediators to regulatory mechanisms of inflammation in atherosclerosis. Hamostaseologie 2015; 35(2): 99, 101. https://www.ncbi.nlm.nih.gov/pubmed/25943077
- Weber C, Lip GY. Editors' Choice papers in Thrombosis and Haemostasis. Thromb Haemost 2015; 113(1): 217-20. https://www.ncbi.nlm.nih.gov/pubmed/25567474
- Wei Y, Zhu M, Corbalan-Campos J, Heyll K, Weber C, Schober A. Regulation of Csf1r and Bcl6 in macrophages mediates the stage-specific effects of microRNA-155 on atherosclerosis. Arterioscler Thromb Vasc Biol 2015; 35(4): 796-803. https://www.ncbi.nlm.nih.gov/pubmed/25810298
- Wertenbruch S, Drescher H, Grossarth V, Kroy D, Giebeler A, Erschfeld S, Heinrichs D, Soehnlein O, Trautwein C, Brandenburg LO, Streetz K. The Anti-Microbial Peptide LL-37/CRAMP Is Elevated in Patients with Liver Diseases and Acts as a Protective Factor during Mouse Liver Injury. Digestion 2015; 91(4): 307-17. https://www.ncbi.nlm.nih.gov/pubmed/25998843
- Wirtz TH, Tillmann S, Strussmann T, Kraemer S, Heemskerk JW, Grottke O, Gawaz M, von Hundelshausen P, Bernhagen J. Platelet-derived MIF: a novel platelet chemokine with distinct recruitment properties. Atherosclerosis 2015; 239(1): 1-10. https://www.ncbi.nlm.nih.gov/pubmed/25561410
- Yamano T, Nedjic J, Hinterberger M, Steinert M, Koser S, Pinto S, Gerdes N, Lutgens E, Ishimaru N, Busslinger M, Brors B, Kyewski B, Klein L. Thymic B Cells Are Licensed to Present Self Antigens for Central T Cell Tolerance Induction. Immunity 2015; 42(6): 1048-61. https://www.ncbi.nlm.nih.gov/pubmed/26070482
- Yin C, Mohanta S, Ma Z, Weber C, Hu D, Weih F, Habenicht A. Generation of Aorta Transcript Atlases of Wild-Type and Apolipoprotein E-null Mice by Laser Capture Microdissection-Based mRNA Expression Microarrays. In: Methods in Molecular Biology. Springer New York 2015; pp. 297-308.
- Zarzycka B, Nicolaes GA, Lutgens E. Targeting the adaptive immune system: new strategies in the treatment of atherosclerosis. Expert Rev Clin Pharmacol 2015; 8(3): 297-313. https://www.ncbi.nlm.nih.gov/pubmed/25843158
- Zarzycka B, Seijkens T, Nabuurs SB, Ritschel T, Grommes J, Soehnlein O, Schrijver R, van Tiel CM, Hackeng TM, Weber C, Giehler F, Kieser A, Lutgens E, Vriend G, Nicolaes GA. Discovery of small molecule CD40-TRAF6 inhibitors. J Chem Inf Model 2015; 55(2): 294-307. https://www.ncbi.nlm.nih.gov/pubmed/25622654
- Zirlik A, Lutgens E. An inflammatory link in atherosclerosis and obesity. Co-stimulatory molecules. Hamostaseologie 2015; 35(3): 272-8. https://www.ncbi.nlm.nih.gov/pubmed/26225729
- Aoqui C, Chmielewski S, Scherer E, Eissler R, Sollinger D, Heid I, Braren R, Schmaderer C, Megens RT, Weber C, Heemann U, Tschop M, Baumann M. Microvascular dysfunction in the course of metabolic syndrome induced by high-fat diet. Cardiovasc Diabetol 2014; 13: 31. https://www.ncbi.nlm.nih.gov/pubmed/24490784
- Bang C, Batkai S, Dangwal S, Gupta SK, Foinquinos A, Holzmann A, Just A, Remke J, Zimmer K, Zeug A, Ponimaskin E, Schmiedl A, Yin X, Mayr M, Halder R, Fischer A, Engelhardt S, Wei Y, Schober A, Fiedler J, Thum T. Cardiac fibroblast-derived microRNA passenger strand-enriched exosomes mediate cardiomyocyte hypertrophy. J Clin Invest 2014; 124(5): 2136-46. https://www.ncbi.nlm.nih.gov/pubmed/24743145
- Blanchet X, Cesarek K, Brandt J, Herwald H, Teupser D, Kuchenhoff H, Karshovska E, Mause SF, Siess W, Wasmuth H, Soehnlein O, Koenen RR, Weber C, von Hundelshausen P. Inflammatory role and prognostic value of platelet chemokines in acute coronary syndrome. Thromb Haemost 2014; 112(6): 1277-87. https://www.ncbi.nlm.nih.gov/pubmed/25183015
- Brantl SA, Khandoga AL, Siess W. Mechanism of platelet activation induced by endocannabinoids in blood and plasma. Platelets 2014; 25(3): 151-61. https://www.ncbi.nlm.nih.gov/pubmed/23789792
- Brantl SA, Khandoga AL, Siess W. Activation of platelets by the endocannabinoids 2-arachidonoylglycerol and virodhamine is mediated by their conversion to arachidonic acid and thromboxane A2, not by activation of cannabinoid receptors. Platelets 2014; 25(6): 465-6. https://www.ncbi.nlm.nih.gov/pubmed/24102401
- Chatzigeorgiou A, Chung KJ, Garcia-Martin R, Alexaki VI, Klotzsche-von Ameln A, Phieler J, Sprott D, Kanczkowski W, Tzanavari T, Bdeir M, Bergmann S, Cartellieri M, Bachmann M, Nikolakopoulou P, Androutsellis-Theotokis A, Siegert G, Bornstein SR, Muders MH, Boon L, Karalis KP, Lutgens E, Chavakis T. Dual role of B7 costimulation in obesity-related nonalcoholic steatohepatitis and metabolic dysregulation. Hepatology 2014; 60(4): 1196-210. https://www.ncbi.nlm.nih.gov/pubmed/24845056
- Chatzigeorgiou A, Seijkens T, Zarzycka B, Engel D, Poggi M, van den Berg S, van den Berg S, Soehnlein O, Winkels H, Beckers L, Lievens D, Driessen A, Kusters P, Biessen E, Garcia-Martin R, Klotzsche-von Ameln A, Gijbels M, Noelle R, Boon L, Hackeng T, Schulte KM, Xu A, Vriend G, Nabuurs S, Chung KJ, Willems van Dijk K, Rensen PC, Gerdes N, de Winther M, Block NL, Schally AV, Weber C, Bornstein SR, Nicolaes G, Chavakis T, Lutgens E. Blocking CD40-TRAF6 signaling is a therapeutic target in obesity-associated insulin resistance. Proc Natl Acad Sci U S A 2014; 111(7): 2686-91. https://www.ncbi.nlm.nih.gov/pubmed/24492375
- Chevre R, Gonzalez-Granado JM, Megens RT, Sreeramkumar V, Silvestre-Roig C, Molina-Sanchez P, Weber C, Soehnlein O, Hidalgo A, Andres V. High-resolution imaging of intravascular atherogenic inflammation in live mice. Circ Res 2014; 114(5): 770-9. https://www.ncbi.nlm.nih.gov/pubmed/24366169
- de Winther MP, Lutgens E. MiR-92a: at the heart of lipid-driven endothelial dysfunction. Circ Res 2014; 114(3): 399-401. https://www.ncbi.nlm.nih.gov/pubmed/24481837
- Doring Y, Noels H, Mandl M, Kramp B, Neideck C, Lievens D, Drechsler M, Megens RT, Tilstam PV, Langer M, Hartwig H, Theelen W, Marth JD, Sperandio M, Soehnlein O, Weber C. Deficiency of the sialyltransferase St3Gal4 reduces Ccl5-mediated myeloid cell recruitment and arrest: short communication. Circ Res 2014; 114(6): 976-81. https://www.ncbi.nlm.nih.gov/pubmed/24425712
- Doring Y, Pawig L, Weber C, Noels H. The CXCL12/CXCR4 chemokine ligand/receptor axis in cardiovascular disease. Front Physiol 2014; 5: 212. https://www.ncbi.nlm.nih.gov/pubmed/24966838
- Doring Y, Soehnlein O, Weber C. Neutrophils cast NETs in atherosclerosis: employing peptidylarginine deiminase as a therapeutic target. Circ Res 2014; 114(6): 931-4. https://www.ncbi.nlm.nih.gov/pubmed/24625721
- Duarte Campos DF, Vogt M, Lindner M, Kirsten A, Weber M, Megens RT, Pyta J, Zenke M, Van Zandvoort M, Fischer H. Two-photon laser scanning microscopy as a useful tool for imaging and evaluating macrophage-, IL-4 activated macrophage- and osteoclast-based in vitro degradation of beta-tricalcium phosphate bone substitute material. Microsc Res Tech 2014; 77(2): 143-52. https://www.ncbi.nlm.nih.gov/pubmed/24282165
- Giebeler A, Streetz KL, Soehnlein O, Neumann U, Wang JM, Brandenburg LO. Deficiency of formyl peptide receptor 1 and 2 is associated with increased inflammation and enhanced liver injury after LPS-stimulation. PLoS One 2014; 9(6): e100522. https://www.ncbi.nlm.nih.gov/pubmed/24956481
- Hartmann P, Schober A, Weber C. MicroRNA-155 and macrophages: a fatty liaison. Cardiovasc Res 2014; 103(1): 5-6. https://www.ncbi.nlm.nih.gov/pubmed/24907979
- Hartwig H, Drechsler M, Lievens D, Kramp B, von Hundelshausen P, Lutgens E, Weber C, Doring Y, Soehnlein O. Platelet-derived PF4 reduces neutrophil apoptosis following arterial occlusion. Thromb Haemost 2014; 111(3): 562-4. https://www.ncbi.nlm.nih.gov/pubmed/24258616
- Hinkel R, Trenkwalder T, Petersen B, Husada W, Gesenhues F, Lee S, Hannappel E, Bock-Marquette I, Theisen D, Leitner L, Boekstegers P, Cierniewski C, Muller OJ, le Noble F, Adams RH, Weinl C, Nordheim A, Reichart B, Weber C, Olson E, Posern G, Deindl E, Niemann H, Kupatt C. MRTF-A controls vessel growth and maturation by increasing the expression of CCN1 and CCN2. Nat Commun 2014; 5(1): 3970. https://www.ncbi.nlm.nih.gov/pubmed/24910328
- Hoeksema MA, Gijbels MJ, Van den Bossche J, van der Velden S, Sijm A, Neele AE, Seijkens T, Stoger JL, Meiler S, Boshuizen MC, Dallinga-Thie GM, Levels JH, Boon L, Mullican SE, Spann NJ, Cleutjens JP, Glass CK, Lazar MA, de Vries CJ, Biessen EA, Daemen MJ, Lutgens E, de Winther MP. Targeting macrophage Histone deacetylase 3 stabilizes atherosclerotic lesions. EMBO Mol Med 2014; 6(9): 1124-32. https://www.ncbi.nlm.nih.gov/pubmed/25007801
- Jaczewska J, Abdulreda MH, Yau CY, Schmitt MM, Schubert I, Berggren PO, Weber C, Koenen RR, Moy VT, Wojcikiewicz EP. TNF-alpha and IFN-gamma promote lymphocyte adhesion to endothelial junctional regions facilitating transendothelial migration. J Leukoc Biol 2014; 95(2): 265-74. https://www.ncbi.nlm.nih.gov/pubmed/24072879
- Kapopara PR, von Felden J, Soehnlein O, Wang Y, Napp LC, Sonnenschein K, Wollert KC, Schieffer B, Gaestel M, Bauersachs J, Bavendiek U. Deficiency of MAPK-activated protein kinase 2 (MK2) prevents adverse remodelling and promotes endothelial healing after arterial injury. Thromb Haemost 2014; 112(6): 1264-76. https://www.ncbi.nlm.nih.gov/pubmed/25120198
- Kwak BR, Back M, Bochaton-Piallat ML, Caligiuri G, Daemen MJ, Davies PF, Hoefer IE, Holvoet P, Jo H, Krams R, Lehoux S, Monaco C, Steffens S, Virmani R, Weber C, Wentzel JJ, Evans PC. Biomechanical factors in atherosclerosis: mechanisms and clinical implications. Eur Heart J 2014; 35(43): 3013-20, 20a-20d. https://www.ncbi.nlm.nih.gov/pubmed/25230814
- Li X, Zhu M, Penfold ME, Koenen RR, Thiemann A, Heyll K, Akhtar S, Koyadan S, Wu Z, Gremse F, Kiessling F, van Zandvoort M, Schall TJ, Weber C, Schober A. Activation of CXCR7 limits atherosclerosis and improves hyperlipidemia by increasing cholesterol uptake in adipose tissue. Circulation 2014; 129(11): 1244-53. https://www.ncbi.nlm.nih.gov/pubmed/24374972
- Lip GYH, Weber C. A very happy new year 2014 from Thrombosis and Haemostasis! Reflections on the past, the present and the future 2014; 111(01): 1-2. http://www.thieme-connect.de/products/ejournals/abstract/10.1055/s-0037-1608911
- Lutgens E. CD40-CD40L: a Janus-faced interaction. Thromb Haemost 2014; 112(2): 223. https://www.ncbi.nlm.nih.gov/pubmed/25007918
- Mandl M, Schmitz S, Weber C, Hristov M. Characterization of the CD14++CD16+ monocyte population in human bone marrow. PLoS One 2014; 9(11): e112140. https://www.ncbi.nlm.nih.gov/pubmed/25369328
- Mastropasqua R, Toto L, Cipollone F, Santovito D, Carpineto P, Mastropasqua L. Role of microRNAs in the modulation of diabetic retinopathy. Prog Retin Eye Res 2014; 43: 92-107. https://www.ncbi.nlm.nih.gov/pubmed/25128741
- Merres J, Hoss J, Albrecht LJ, Kress E, Soehnlein O, Jansen S, Pufe T, Tauber SC, Brandenburg LO. Role of the cathelicidin-related antimicrobial peptide in inflammation and mortality in a mouse model of bacterial meningitis. J Innate Immun 2014; 6(2): 205-18. https://www.ncbi.nlm.nih.gov/pubmed/23969854
- Mion F, D'Inca F, Danelli L, Toffoletto B, Guarnotta C, Frossi B, Burocchi A, Rigoni A, Gerdes N, Lutgens E, Tripodo C, Colombo MP, Rivera J, Vitale G, Pucillo CE. Mast cells control the expansion and differentiation of IL-10-competent B cells. J Immunol 2014; 193(9): 4568-79. https://www.ncbi.nlm.nih.gov/pubmed/25267976
- Mohanta SK, Yin C, Peng L, Srikakulapu P, Bontha V, Hu D, Weih F, Weber C, Gerdes N, Habenicht AJ. Artery tertiary lymphoid organs contribute to innate and adaptive immune responses in advanced mouse atherosclerosis. Circ Res 2014; 114(11): 1772-87. https://www.ncbi.nlm.nih.gov/pubmed/24855201
- Natarelli L, Schober A. Janus-faced role of Kruppel-like factor 2-dependent regulation of microRNAs in endothelial proliferation. Arterioscler Thromb Vasc Biol 2014; 34(8): 1605-6. https://www.ncbi.nlm.nih.gov/pubmed/25031325
- Nencioni A, da Silva RF, Fraga-Silva RA, Steffens S, Fabre M, Bauer I, Caffa I, Magnone M, Sociali G, Quercioli A, Pelli G, Lenglet S, Galan K, Burger F, Vazquez Calvo S, Bertolotto M, Bruzzone S, Ballestrero A, Patrone F, Dallegri F, Santos RA, Stergiopulos N, Mach F, Vuilleumier N, Montecucco F. Nicotinamide phosphoribosyltransferase inhibition reduces intraplaque CXCL1 production and associated neutrophil infiltration in atherosclerotic mice. Thromb Haemost 2014; 111(2): 308-22. https://www.ncbi.nlm.nih.gov/pubmed/24196571
- Noels H, Zhou B, Tilstam PV, Theelen W, Li X, Pawig L, Schmitz C, Akhtar S, Simsekyilmaz S, Shagdarsuren E, Schober A, Adams RH, Bernhagen J, Liehn EA, Doring Y, Weber C. Deficiency of endothelial CXCR4 reduces reendothelialization and enhances neointimal hyperplasia after vascular injury in atherosclerosis-prone mice. Arterioscler Thromb Vasc Biol 2014; 34(6): 1209-20. https://www.ncbi.nlm.nih.gov/pubmed/24723559
- Oldekamp S, Pscheidl S, Kress E, Soehnlein O, Jansen S, Pufe T, Wang JM, Tauber SC, Brandenburg LO. Lack of formyl peptide receptor 1 and 2 leads to more severe inflammation and higher mortality in mice with of pneumococcal meningitis. Immunology 2014; 143(3): 447-61. https://www.ncbi.nlm.nih.gov/pubmed/24863484
- Popp T, Steinritz D, Breit A, Deppe J, Egea V, Schmidt A, Gudermann T, Weber C, Ries C. Wnt5a/beta-catenin signaling drives calcium-induced differentiation of human primary keratinocytes. J Invest Dermatol 2014; 134(8): 2183-91. https://www.ncbi.nlm.nih.gov/pubmed/24658506
- Projahn D, Simsekyilmaz S, Singh S, Kanzler I, Kramp BK, Langer M, Burlacu A, Bernhagen J, Klee D, Zernecke A, Hackeng TM, Groll J, Weber C, Liehn EA, Koenen RR. Controlled intramyocardial release of engineered chemokines by biodegradable hydrogels as a treatment approach of myocardial infarction. J Cell Mol Med 2014; 18(5): 790-800. https://www.ncbi.nlm.nih.gov/pubmed/24512349
- Rassaf T, Weber C, Bernhagen J. Macrophage migration inhibitory factor in myocardial ischaemia/reperfusion injury. Cardiovasc Res 2014; 102(2): 321-8. https://www.ncbi.nlm.nih.gov/pubmed/24675723
- Richter R, Jochheim-Richter A, Ciuculescu F, Kollar K, Seifried E, Forssmann U, Verzijl D, Smit MJ, Blanchet X, von Hundelshausen P, Weber C, Forssmann WG, Henschler R. Identification and characterization of circulating variants of CXCL12 from human plasma: effects on chemotaxis and mobilization of hematopoietic stem and progenitor cells. Stem Cells Dev 2014; 23(16): 1959-74. https://www.ncbi.nlm.nih.gov/pubmed/24708339
- Ries C. Cytokine functions of TIMP-1. Cell Mol Life Sci 2014; 71(4): 659-72. https://www.ncbi.nlm.nih.gov/pubmed/23982756
- Ring L, Neth P, Weber C, Steffens S, Faussner A. beta-Catenin-dependent pathway activation by both promiscuous "canonical" WNT3a-, and specific "noncanonical" WNT4- and WNT5a-FZD receptor combinations with strong differences in LRP5 and LRP6 dependency. Cell Signal 2014; 26(2): 260-7. https://www.ncbi.nlm.nih.gov/pubmed/24269653
- Rossaint J, Herter JM, Van Aken H, Napirei M, Doring Y, Weber C, Soehnlein O, Zarbock A. Synchronized integrin engagement and chemokine activation is crucial in neutrophil extracellular trap-mediated sterile inflammation. Blood 2014; 123(16): 2573-84. https://www.ncbi.nlm.nih.gov/pubmed/24335230
- Santovito D, De Nardis V, Marcantonio P, Mandolini C, Paganelli C, Vitale E, Buttitta F, Bucci M, Mezzetti A, Consoli A, Cipollone F. Plasma exosome microRNA profiling unravels a new potential modulator of adiponectin pathway in diabetes: effect of glycemic control. J Clin Endocrinol Metab 2014; 99(9): E1681-5. https://www.ncbi.nlm.nih.gov/pubmed/24937531
- Schiener M, Hossann M, Viola JR, Ortega-Gomez A, Weber C, Lauber K, Lindner LH, Soehnlein O. Nanomedicine-based strategies for treatment of atherosclerosis. Trends Mol Med 2014; 20(5): 271-81. https://www.ncbi.nlm.nih.gov/pubmed/24594264
- Schmitt MM, Fraemohs L, Hackeng TM, Weber C, Koenen RR. Atherogenic mononuclear cell recruitment is facilitated by oxidized lipoprotein-induced endothelial junctional adhesion molecule-A redistribution. Atherosclerosis 2014; 234(2): 254-64. https://www.ncbi.nlm.nih.gov/pubmed/24704627
- Schmitt MM, Megens RT, Zernecke A, Bidzhekov K, van den Akker NM, Rademakers T, van Zandvoort MA, Hackeng TM, Koenen RR, Weber C. Endothelial junctional adhesion molecule-a guides monocytes into flow-dependent predilection sites of atherosclerosis. Circulation 2014; 129(1): 66-76. https://www.ncbi.nlm.nih.gov/pubmed/24065611
- Schober A, Nazari-Jahantigh M, Wei Y, Bidzhekov K, Gremse F, Grommes J, Megens RT, Heyll K, Noels H, Hristov M, Wang S, Kiessling F, Olson EN, Weber C. MicroRNA-126-5p promotes endothelial proliferation and limits atherosclerosis by suppressing Dlk1. Nat Med 2014; 20(4): 368-76. https://www.ncbi.nlm.nih.gov/pubmed/24584117
- Seijkens T, Hoeksema MA, Beckers L, Smeets E, Meiler S, Levels J, Tjwa M, de Winther MP, Lutgens E. Hypercholesterolemia-induced priming of hematopoietic stem and progenitor cells aggravates atherosclerosis. FASEB J 2014; 28(5): 2202-13. https://www.ncbi.nlm.nih.gov/pubmed/24481967
- Seijkens T, Kusters P, Chatzigeorgiou A, Chavakis T, Lutgens E. Immune cell crosstalk in obesity: a key role for costimulation? Diabetes 2014; 63(12): 3982-91. https://www.ncbi.nlm.nih.gov/pubmed/25414012
- Silvestre-Roig C, de Winther MP, Weber C, Daemen MJ, Lutgens E, Soehnlein O. Atherosclerotic plaque destabilization: mechanisms, models, and therapeutic strategies. Circ Res 2014; 114(1): 214-26. https://www.ncbi.nlm.nih.gov/pubmed/24385514
- Simsekyilmaz S, Cabrera-Fuentes HA, Meiler S, Kostin S, Baumer Y, Liehn EA, Weber C, Boisvert WA, Preissner KT, Zernecke A. Role of extracellular RNA in atherosclerotic plaque formation in mice. Circulation 2014; 129(5): 598-606. https://www.ncbi.nlm.nih.gov/pubmed/24201302
- Simsekyilmaz S, Cabrera-Fuentes HA, Meiler S, Kostin S, Baumer Y, Liehn EA, Weber C, Boisvert WA, Preissner KT, Zernecke A. Response to letter regarding article "Role of extracellular RNA in atherosclerotic plaque formation in mice". Circulation 2014; 130(16): e144-5. https://www.ncbi.nlm.nih.gov/pubmed/25311624
- Soehnlein O. Macrophages shine bright. Blood 2014; 124(15): 2320-2. https://www.ncbi.nlm.nih.gov/pubmed/25301333
- Soehnlein O. The ABC of Thrombopoiesis. Arterioscler Thromb Vasc Biol 2014; 34(4): 700-1. https://www.ncbi.nlm.nih.gov/pubmed/24665122
- Sreeramkumar V, Adrover JM, Ballesteros I, Cuartero MI, Rossaint J, Bilbao I, Nacher M, Pitaval C, Radovanovic I, Fukui Y, McEver RP, Filippi MD, Lizasoain I, Ruiz-Cabello J, Zarbock A, Moro MA, Hidalgo A. Neutrophils scan for activated platelets to initiate inflammation. Science 2014; 346(6214): 1234-8. https://www.ncbi.nlm.nih.gov/pubmed/25477463
- Steffens S. Fine tuning effector and regulatory T-cell dynamics: a novel tool for plaque regression? Cardiovasc Res 2014; 102(1): 3-5. https://www.ncbi.nlm.nih.gov/pubmed/24556952
- Tilstam PV, Gijbels MJ, Habbeddine M, Cudejko C, Asare Y, Theelen W, Zhou B, Doring Y, Drechsler M, Pawig L, Simsekyilmaz S, Koenen RR, de Winther MP, Lawrence T, Bernhagen J, Zernecke A, Weber C, Noels H. Bone marrow-specific knock-in of a non-activatable Ikkalpha kinase mutant influences haematopoiesis but not atherosclerosis in Apoe-deficient mice. PLoS One 2014; 9(2): e87452. https://www.ncbi.nlm.nih.gov/pubmed/24498325
- von Hundelshausen P, Schmitt MM. Platelets and their chemokines in atherosclerosis-clinical applications. Front Physiol 2014; 5: 294. https://www.ncbi.nlm.nih.gov/pubmed/25152735
- Wan M, Soehnlein O, Tang X, van der Does AM, Smedler E, Uhlen P, Lindbom L, Agerberth B, Haeggstrom JZ. Cathelicidin LL-37 induces time-resolved release of LTB4 and TXA2 by human macrophages and triggers eicosanoid generation in vivo. FASEB J 2014; 28(8): 3456-67. https://www.ncbi.nlm.nih.gov/pubmed/24736410
- Weber C, Lip GYH. Editors’ Choice papers in Thrombosis and Haemostasis. Thromb Haemost 2014; 111(01): 183-188. http://www.thieme-connect.de/products/ejournals/abstract/10.1055/s-0037-1608912
- Wild J, Soehnlein O, Dietel B, Urschel K, Garlichs CD, Cicha I. Rubbing salt into wounded endothelium: sodium potentiates proatherogenic effects of TNF-alpha under non-uniform shear stress. Thromb Haemost 2014; 112(1): 183-95. https://www.ncbi.nlm.nih.gov/pubmed/24573382
- Wildhagen KC, Garcia de Frutos P, Reutelingsperger CP, Schrijver R, Areste C, Ortega-Gomez A, Deckers NM, Hemker HC, Soehnlein O, Nicolaes GA. Nonanticoagulant heparin prevents histone-mediated cytotoxicity in vitro and improves survival in sepsis. Blood 2014; 123(7): 1098-101. https://www.ncbi.nlm.nih.gov/pubmed/24264231
- Wildhagen KC, Schrijver R, Beckers L, ten Cate H, Reutelingsperger CP, Lutgens E, Nicolaes GA. Effects of exogenous recombinant APC in mouse models of ischemia reperfusion injury and of atherosclerosis. PLoS One 2014; 9(7): e101446. https://www.ncbi.nlm.nih.gov/pubmed/25032959
- Winkels H, Weber C, Lutgens E, Gerdes N. Atherosclerosis: cell biology and lipoproteins focus on iNKT cells and CD40/CD40L in atherosclerosis and metabolic disorders. Curr Opin Lipidol 2014; 25(5): 408-9. https://www.ncbi.nlm.nih.gov/pubmed/25186203
- Zernecke A, Weber C. Chemokines in atherosclerosis: proceedings resumed. Arterioscler Thromb Vasc Biol 2014; 34(4): 742-50. https://www.ncbi.nlm.nih.gov/pubmed/24436368
- Akhtar S, Gremse F, Kiessling F, Weber C, Schober A. CXCL12 promotes the stabilization of atherosclerotic lesions mediated by smooth muscle progenitor cells in Apoe-deficient mice. Arterioscler Thromb Vasc Biol 2013; 33(4): 679-686. https://www.ncbi.nlm.nih.gov/pubmed/23393393
- Asare Y, Shagdarsuren E, Schmid JA, Tilstam PV, Grommes J, El Bounkari O, Schutz AK, Weber C, de Winther MP, Noels H, Bernhagen J. Endothelial CSN5 impairs NF-kappaB activation and monocyte adhesion to endothelial cells and is highly expressed in human atherosclerotic lesions. Thromb Haemost 2013; 110(1): 141-152. https://www.ncbi.nlm.nih.gov/pubmed/23636414
- Badr Eslam R, Lang IM, Koppensteiner R, Calatzis A, Panzer S, Gremmel T. Residual platelet activation through protease-activated receptors (PAR)-1 and -4 in patients on P2Y12 inhibitors. Int J Cardiol 2013; 168(1): 403-406. https://www.ncbi.nlm.nih.gov/pubmed/23041015
- Borissoff JI, Otten JJ, Heeneman S, Leenders P, van Oerle R, Soehnlein O, Loubele ST, Hamulyak K, Hackeng TM, Daemen MJ, Degen JL, Weiler H, Esmon CT, van Ryn J, Biessen EA, Spronk HM, ten Cate H. Genetic and pharmacological modifications of thrombin formation in apolipoprotein e-deficient mice determine atherosclerosis severity and atherothrombosis onset in a neutrophil-dependent manner. PLoS One 2013; 8(2): e55784. https://www.ncbi.nlm.nih.gov/pubmed/23409043
- Bras G, Bochenska O, Rapala-Kozik M, Guevara-Lora I, Faussner A, Kamysz W, Kozik A. Release of biologically active kinin peptides, Met-Lys-bradykinin and Leu-Met-Lys-bradykinin from human kininogens by two major secreted aspartic proteases of Candida parapsilosis. Peptides 2013; 48: 114-123. https://www.ncbi.nlm.nih.gov/pubmed/23954712
- Casanova-Acebes M, Pitaval C, Weiss LA, Nombela-Arrieta C, Chevre R, N AG, Kunisaki Y, Zhang D, van Rooijen N, Silberstein LE, Weber C, Nagasawa T, Frenette PS, Castrillo A, Hidalgo A. Rhythmic modulation of the hematopoietic niche through neutrophil clearance. Cell 2013; 153(5): 1025-1035. https://www.ncbi.nlm.nih.gov/pubmed/23706740
- Doring Y, Weber C, Soehnlein O. Footprints of neutrophil extracellular traps as predictors of cardiovascular risk. Arterioscler Thromb Vasc Biol 2013; 33(8): 1735-1736. https://www.ncbi.nlm.nih.gov/pubmed/23818484
- Drechsler M, Soehnlein O. The complexity of arterial classical monocyte recruitment. J Innate Immun 2013; 5(4): 358-366. https://www.ncbi.nlm.nih.gov/pubmed/23571485
- Drechsler M, Soehnlein O, Weber C. Nitric oxide-donating statins upgrade the benefits of lipid-lowering in vascular inflammation by desensitizing neutrophil activation: editorial to: "Nitric oxide-donating atorvastatin attenuates neutrophil recruitment during vascular inflammation independent of changes in plasma cholesterol" by R. Baetta et al. Cardiovasc Drugs Ther 2013; 27(3): 183-185. https://www.ncbi.nlm.nih.gov/pubmed/23440356
- Fujita B, Strodthoff D, Fritzenwanger M, Pfeil A, Ferrari M, Goebel B, Figulla HR, Gerdes N, Jung C. Altered red blood cell distribution width in overweight adolescents and its association with markers of inflammation. Pediatr Obes 2013; 8(5): 385-391. https://www.ncbi.nlm.nih.gov/pubmed/23239558
- Gerdes N, Winkels H, Weber C. Atherosclerosis: cell biology and lipoproteins-focus on anti-inflammatory mechanisms as therapeutic options. Curr Opin Lipidol 2013; 24(2): 187-188. https://www.ncbi.nlm.nih.gov/pubmed/23481233
- Ghosh M, van den Akker NM, Wijnands KA, Poeze M, Weber C, McQuade LE, Pluth MD, Lippard SJ, Post MJ, Molin DG, van Zandvoort MA. Specific visualization of nitric oxide in the vasculature with two-photon microscopy using a copper based fluorescent probe. PLoS One 2013; 8(9): e75331. https://www.ncbi.nlm.nih.gov/pubmed/24086509
- Goyal P, Pandey D, Brunnert D, Hammer E, Zygmunt M, Siess W. Cofilin oligomer formation occurs in vivo and is regulated by cofilin phosphorylation. PLoS One 2013; 8(8): e71769. https://www.ncbi.nlm.nih.gov/pubmed/23951242
- Heymans S, Corsten MF, Verhesen W, Carai P, van Leeuwen RE, Custers K, Peters T, Hazebroek M, Stoger L, Wijnands E, Janssen BJ, Creemers EE, Pinto YM, Grimm D, Schurmann N, Vigorito E, Thum T, Stassen F, Yin X, Mayr M, de Windt LJ, Lutgens E, Wouters K, de Winther MP, Zacchigna S, Giacca M, van Bilsen M, Papageorgiou AP, Schroen B. Macrophage microRNA-155 promotes cardiac hypertrophy and failure. Circulation 2013; 128(13): 1420-1432. https://www.ncbi.nlm.nih.gov/pubmed/23956210
- Kanzler I, Tuchscheerer N, Steffens G, Simsekyilmaz S, Konschalla S, Kroh A, Simons D, Asare Y, Schober A, Bucala R, Weber C, Bernhagen J, Liehn EA. Differential roles of angiogenic chemokines in endothelial progenitor cell-induced angiogenesis. Basic Res Cardiol 2013; 108(1): 310. https://www.ncbi.nlm.nih.gov/pubmed/23184390
- Karshovska E, Weber C, von Hundelshausen P. Platelet chemokines in health and disease. Thromb Haemost 2013; 110(5): 894-902. https://www.ncbi.nlm.nih.gov/pubmed/23783401
- Klingenberg R, Gerdes N, Badeau RM, Gistera A, Strodthoff D, Ketelhuth DF, Lundberg AM, Rudling M, Nilsson SK, Olivecrona G, Zoller S, Lohmann C, Luscher TF, Jauhiainen M, Sparwasser T, Hansson GK. Depletion of FOXP3+ regulatory T cells promotes hypercholesterolemia and atherosclerosis. J Clin Invest 2013; 123(3): 1323-1334. https://www.ncbi.nlm.nih.gov/pubmed/23426179
- Kozik A, Faussner A, Blonska B, Guevara-Lora I. Kinin-generating cellular model obtained from human glioblastoma cell line U-373. Acta Biochimica Polonica 2013; 60(3). http://dx.doi.org/10.18388/abp.2013_1985
- Kramp BK, Megens RT, Sarabi A, Winkler S, Projahn D, Weber C, Koenen RR, von Hundelshausen P. Exchange of extracellular domains of CCR1 and CCR5 reveals confined functions in CCL5-mediated cell recruitment. Thromb Haemost 2013; 110(4): 795-806. https://www.ncbi.nlm.nih.gov/pubmed/23925484
- Kumar N, Ippel H, Weber C, Hackeng T, Mayo KH. Protein lysine-Nzeta alkylation and O-phosphorylation mediated by DTT-generated reactive oxygen species. Protein Sci 2013; 22(3): 327-346. https://www.ncbi.nlm.nih.gov/pubmed/23315912
- Langer HF, Weber C, Gawaz M. The platelet--thrombosis and beyond. Thromb Haemost 2013; 110(5): 857-858. https://www.ncbi.nlm.nih.gov/pubmed/24108387
- Legein B, Temmerman L, Biessen EA, Lutgens E. Inflammation and immune system interactions in atherosclerosis. Cell Mol Life Sci 2013; 70(20): 3847-3869. https://www.ncbi.nlm.nih.gov/pubmed/23430000
- Lenglet S, Thomas A, Soehnlein O, Montecucco F, Burger F, Pelli G, Galan K, Cravatt B, Staub C, Steffens S. Fatty acid amide hydrolase deficiency enhances intraplaque neutrophil recruitment in atherosclerotic mice. Arterioscler Thromb Vasc Biol 2013; 33(2): 215-223. https://www.ncbi.nlm.nih.gov/pubmed/23241405
- Leschner J, Wennerberg G, Feierler J, Bermudez M, Welte B, Kalatskaya I, Wolber G, Faussner A. Interruption of the ionic lock in the bradykinin B2 receptor results in constitutive internalization and turns several antagonists into strong agonists. J Pharmacol Exp Ther 2013; 344(1): 85-95. https://www.ncbi.nlm.nih.gov/pubmed/23086229
- Liehn EA, Kanzler I, Konschalla S, Kroh A, Simsekyilmaz S, Sonmez TT, Bucala R, Bernhagen J, Weber C. Compartmentalized protective and detrimental effects of endogenous macrophage migration-inhibitory factor mediated by CXCR2 in a mouse model of myocardial ischemia/reperfusion. Arterioscler Thromb Vasc Biol 2013; 33(9): 2180-2186. https://www.ncbi.nlm.nih.gov/pubmed/23868943
- Lievens D, Habets KL, Robertson AK, Laouar Y, Winkels H, Rademakers T, Beckers L, Wijnands E, Boon L, Mosaheb M, Ait-Oufella H, Mallat Z, Flavell RA, Rudling M, Binder CJ, Gerdes N, Biessen EA, Weber C, Daemen MJ, Kuiper J, Lutgens E. Abrogated transforming growth factor beta receptor II (TGFbetaRII) signalling in dendritic cells promotes immune reactivity of T cells resulting in enhanced atherosclerosis. Eur Heart J 2013; 34(48): 3717-3727. https://www.ncbi.nlm.nih.gov/pubmed/22613345
- Lundberg AM, Ketelhuth DF, Johansson ME, Gerdes N, Liu S, Yamamoto M, Akira S, Hansson GK. Toll-like receptor 3 and 4 signalling through the TRIF and TRAM adaptors in haematopoietic cells promotes atherosclerosis. Cardiovasc Res 2013; 99(2): 364-373. https://www.ncbi.nlm.nih.gov/pubmed/23417039
- Manthey HD, Cochain C, Barnsteiner S, Karshovska E, Pelisek J, Koch M, Chaudhari SM, Busch M, Eckstein HH, Weber C, Koenen RR, Zernecke A. CCR6 selectively promotes monocyte mediated inflammation and atherogenesis in mice. Thromb Haemost 2013; 110(6): 1267-1277. https://www.ncbi.nlm.nih.gov/pubmed/24114205
- Molica F, Burger F, Thomas A, Staub C, Tailleux A, Staels B, Pelli G, Zimmer A, Cravatt B, Matter CM, Pacher P, Steffens S. Endogenous cannabinoid receptor CB1 activation promotes vascular smooth-muscle cell proliferation and neointima formation. J Lipid Res 2013; 54(5): 1360-1368. https://www.ncbi.nlm.nih.gov/pubmed/23479425
- Nakahata AM, Mayer B, Neth P, Hansen D, Sampaio MU, Oliva ML. Blocking the proliferation of human tumor cell lines by peptidase inhibitors from Bauhinia seeds. Planta Med 2013; 79(3-4): 227-235. https://www.ncbi.nlm.nih.gov/pubmed/23345168
- Neth P, Nazari-Jahantigh M, Schober A, Weber C. MicroRNAs in flow-dependent vascular remodelling. Cardiovasc Res 2013; 99(2): 294-303. https://www.ncbi.nlm.nih.gov/pubmed/23612583
- Oral H, Kanzler I, Tuchscheerer N, Curaj A, Simsekyilmaz S, Sonmez TT, Radu E, Postea O, Weber C, Schuh A, Liehn EA. CXC chemokine KC fails to induce neutrophil infiltration and neoangiogenesis in a mouse model of myocardial infarction. J Mol Cell Cardiol 2013; 60: 1-7. https://www.ncbi.nlm.nih.gov/pubmed/23598282
- Ortega-Gomez A, Perretti M, Soehnlein O. Resolution of inflammation: an integrated view. EMBO Mol Med 2013; 5(5): 661-674. https://www.ncbi.nlm.nih.gov/pubmed/23592557
- Petzold T, Ruppert R, Pandey D, Barocke V, Meyer H, Lorenz M, Zhang L, Siess W, Massberg S, Moser M. beta1 integrin-mediated signals are required for platelet granule secretion and hemostasis in mouse. Blood 2013; 122(15): 2723-2731. https://www.ncbi.nlm.nih.gov/pubmed/24004668
- Poti F, Gualtieri F, Sacchi S, Weissen-Plenz G, Varga G, Brodde M, Weber C, Simoni M, Nofer JR. KRP-203, sphingosine 1-phosphate receptor type 1 agonist, ameliorates atherosclerosis in LDL-R-/- mice. Arterioscler Thromb Vasc Biol 2013; 33(7): 1505-1512. https://www.ncbi.nlm.nih.gov/pubmed/23640484
- Preissner KT, Weber C. Go with the flow: the passion for vascular biology research. Highlights from IVBM 2012. Thromb Haemost 2013; 109(3): 366-367. https://www.ncbi.nlm.nih.gov/pubmed/23407867
- Schaffer S, Tandon R, Zipse H, Siess W, Schmidt A, Jamasbi J, Karshovska E, Steglich W, Lorenz R. Stereo specific platelet inhibition by the natural LXR agonist 22(R)-OH-cholesterol and its fluorescence labelling with preserved bioactivity and chiral handling in macrophages. Biochem Pharmacol 2013; 86(2): 279-285. https://www.ncbi.nlm.nih.gov/pubmed/23665353
- Seijkens T, Kusters P, Engel D, Lutgens E. CD40-CD40L: linking pancreatic, adipose tissue and vascular inflammation in type 2 diabetes and its complications. Diab Vasc Dis Res 2013; 10(2): 115-122. https://www.ncbi.nlm.nih.gov/pubmed/22965071
- Smeets E, Meiler S, Lutgens E. Lymphocytic tumor necrosis factor receptor superfamily co-stimulatory molecules in the pathogenesis of atherosclerosis. Curr Opin Lipidol 2013; 24(6): 518-524. https://www.ncbi.nlm.nih.gov/pubmed/24184937
- Soehnlein O. Myeloid cells in traffic. J Innate Immun 2013; 5(4): 301-303. https://www.ncbi.nlm.nih.gov/pubmed/23594523
- Soehnlein O, Drechsler M, Doring Y, Lievens D, Hartwig H, Kemmerich K, Ortega-Gomez A, Mandl M, Vijayan S, Projahn D, Garlichs CD, Koenen RR, Hristov M, Lutgens E, Zernecke A, Weber C. Distinct functions of chemokine receptor axes in the atherogenic mobilization and recruitment of classical monocytes. EMBO Mol Med 2013; 5(3): 471-481. https://www.ncbi.nlm.nih.gov/pubmed/23417922
- Soehnlein O, Swirski FK. Hypercholesterolemia links hematopoiesis with atherosclerosis. Trends Endocrinol Metab 2013; 24(3): 129-136. https://www.ncbi.nlm.nih.gov/pubmed/23228326
- Strodthoff D, Lundberg AM, Agardh HE, Ketelhuth DF, Paulsson-Berne G, Arner P, Hansson GK, Gerdes N. Lack of invariant natural killer T cells affects lipid metabolism in adipose tissue of diet-induced obese mice. Arterioscler Thromb Vasc Biol 2013; 33(6): 1189-1196. https://www.ncbi.nlm.nih.gov/pubmed/23520162
- Strussmann T, Tillmann S, Wirtz T, Bucala R, von Hundelshausen P, Bernhagen J. Platelets are a previously unrecognised source of MIF. Thromb Haemost 2013; 110(5): 1004-1013. https://www.ncbi.nlm.nih.gov/pubmed/23846621
- von Hundelshausen P, Weber C. [Chronic inflammation and atherosclerosis]. Dtsch Med Wochenschr 2013; 138(37): 1839-1844. https://www.ncbi.nlm.nih.gov/pubmed/24006166
- Wantha S, Alard JE, Megens RT, van der Does AM, Doring Y, Drechsler M, Pham CT, Wang MW, Wang JM, Gallo RL, von Hundelshausen P, Lindbom L, Hackeng T, Weber C, Soehnlein O. Neutrophil-derived cathelicidin promotes adhesion of classical monocytes. Circ Res 2013; 112(5): 792-801. https://www.ncbi.nlm.nih.gov/pubmed/23283724
- Weber C. MicroRNAs: from basic mechanisms to clinical application in cardiovascular medicine. Arterioscler Thromb Vasc Biol 2013; 33(2): 168-169. https://www.ncbi.nlm.nih.gov/pubmed/23325472
- Weber C, Lip GYH. Editors’ Choice papers in Thrombosis and Haemostasis. Thrombosis and Haemostasis 2013; 109(01): 170-173. http://dx.doi.org/10.1055/s-0037-1609008
- Weber C, Lip GYH. A Happy New Year 2013 for Thrombosis and Haemostasis …. Thrombosis and Haemostasis 2013; 109(01): 1-2. http://dx.doi.org/10.1055/s-0037-1609007
- Wei Y, Nazari-Jahantigh M, Chan L, Zhu M, Heyll K, Corbalan-Campos J, Hartmann P, Thiemann A, Weber C, Schober A. The microRNA-342-5p fosters inflammatory macrophage activation through an Akt1- and microRNA-155-dependent pathway during atherosclerosis. Circulation 2013; 127(15): 1609-1619. https://www.ncbi.nlm.nih.gov/pubmed/23513069
- Wei Y, Nazari-Jahantigh M, Neth P, Weber C, Schober A. MicroRNA-126, -145, and -155: a therapeutic triad in atherosclerosis? Arterioscler Thromb Vasc Biol 2013; 33(3): 449-454. https://www.ncbi.nlm.nih.gov/pubmed/23324496
- Wei Y, Schober A, Weber C. Pathogenic arterial remodeling: the good and bad of microRNAs. Am J Physiol Heart Circ Physiol 2013; 304(8): H1050-1059. https://www.ncbi.nlm.nih.gov/pubmed/23396454
- Wu Z, Curaj A, Fokong S, Liehn EA, Weber C, Lammers T, Kiessling F, Zandvoort van M. Rhodamine-loaded intercellular adhesion molecule-1-targeted microbubbles for dual-modality imaging under controlled shear stresses. Circ Cardiovasc Imaging 2013; 6(6): 974-981. https://www.ncbi.nlm.nih.gov/pubmed/24036383
- Yla-Herttuala S, Bentzon JF, Daemen M, Falk E, Garcia-Garcia HM, Herrmann J, Hoefer I, Jauhiainen S, Jukema JW, Krams R, Kwak BR, Marx N, Naruszewicz M, Newby A, Pasterkamp G, Serruys PW, Waltenberger J, Weber C, Tokgozoglu L, Atherosclerosis ESCWGo, Vascular B. Stabilization of atherosclerotic plaques: an update. Eur Heart J 2013; 34(42): 3251-3258. https://www.ncbi.nlm.nih.gov/pubmed/23966311
- Ziegler T, Horstkotte J, Schwab C, Pfetsch V, Weinmann K, Dietzel S, Rohwedder I, Hinkel R, Gross L, Lee S, Hu J, Soehnlein O, Franz WM, Sperandio M, Pohl U, Thomas M, Weber C, Augustin HG, Fassler R, Deutsch U, Kupatt C. Angiopoietin 2 mediates microvascular and hemodynamic alterations in sepsis. J Clin Invest 2013; 123(8): 3436-3445. https://www.ncbi.nlm.nih.gov/pubmed/23863629
- Zimmermann R, Krueger J, Filipovic MR, Ivanovic-Burmazovic I, Calatzis A, Weiss DR, Eckstein R. A detailed examination of platelet function inhibition by nitric oxide in platelet-rich plasma and whole blood. Clin Lab 2013; 59(5-6): 629-638. https://www.ncbi.nlm.nih.gov/pubmed/23865363
- Bampalis VG, Brantl SA, Siess W. Why and how to eliminate spontaneous platelet aggregation in blood measured by multiple electrode aggregometry. J Thromb Haemost 2012; 10(8): 1710-1714. https://www.ncbi.nlm.nih.gov/pubmed/22712617
- Bidzhekov K, Gan L, Denecke B, Rostalsky A, Hristov M, Koeppel TA, Zernecke A, Weber C. microRNA expression signatures and parallels between monocyte subsets and atherosclerotic plaque in humans. Thromb Haemost 2012; 107(4): 619-625. https://www.ncbi.nlm.nih.gov/pubmed/22370758
- Blanchet X, Langer M, Weber C, Koenen RR, von Hundelshausen P. Touch of chemokines. Front Immunol 2012; 3: 175. https://www.ncbi.nlm.nih.gov/pubmed/22807925
- Bras G, Bochenska O, Rapala-Kozik M, Guevara-Lora I, Faussner A, Kozik A. Extracellular aspartic protease SAP2 of Candida albicans yeast cleaves human kininogens and releases proinflammatory peptides, Met-Lys-bradykinin and des-Arg(9)-Met-Lys-bradykinin. Biol Chem 2012; 393(8): 829-839. https://www.ncbi.nlm.nih.gov/pubmed/22944684
- Brauner R, Johannes C, Ploessl F, Bracher F, Lorenz RL. Phytosterols reduce cholesterol absorption by inhibition of 27-hydroxycholesterol generation, liver X receptor alpha activation, and expression of the basolateral sterol exporter ATP-binding cassette A1 in Caco-2 enterocytes. J Nutr 2012; 142(6): 981-989. https://www.ncbi.nlm.nih.gov/pubmed/22535758
- Cardilo-Reis L, Gruber S, Schreier SM, Drechsler M, Papac-Milicevic N, Weber C, Wagner O, Stangl H, Soehnlein O, Binder CJ. Interleukin-13 protects from atherosclerosis and modulates plaque composition by skewing the macrophage phenotype. EMBO Mol Med 2012; 4(10): 1072-1086. https://www.ncbi.nlm.nih.gov/pubmed/23027612
- Djafarzadeh R, Sauter M, Notohamiprodjo S, Noessner E, Goyal P, Siess W, Wornle M, Ribeiro A, Himmelein S, Sitter T, Nelson PJ. Recombinant GPI-anchored TIMP-1 stimulates growth and migration of peritoneal mesothelial cells. PLoS One 2012; 7(4): e33963. https://www.ncbi.nlm.nih.gov/pubmed/22558080
- Doring Y, Drechsler M, Wantha S, Kemmerich K, Lievens D, Vijayan S, Gallo RL, Weber C, Soehnlein O. Lack of neutrophil-derived CRAMP reduces atherosclerosis in mice. Circ Res 2012; 110(8): 1052-1056. https://www.ncbi.nlm.nih.gov/pubmed/22394519
- Doring Y, Manthey HD, Drechsler M, Lievens D, Megens RT, Soehnlein O, Busch M, Manca M, Koenen RR, Pelisek J, Daemen MJ, Lutgens E, Zenke M, Binder CJ, Weber C, Zernecke A. Auto-antigenic protein-DNA complexes stimulate plasmacytoid dendritic cells to promote atherosclerosis. Circulation 2012; 125(13): 1673-1683. https://www.ncbi.nlm.nih.gov/pubmed/22388324
- Doring Y, Noels H, Weber C. The use of high-throughput technologies to investigate vascular inflammation and atherosclerosis. Arterioscler Thromb Vasc Biol 2012; 32(2): 182-195. https://www.ncbi.nlm.nih.gov/pubmed/22258901
- Doring Y, Soehnlein O, Drechsler M, Shagdarsuren E, Chaudhari SM, Meiler S, Hartwig H, Hristov M, Koenen RR, Hieronymus T, Zenke M, Weber C, Zernecke A. Hematopoietic interferon regulatory factor 8-deficiency accelerates atherosclerosis in mice. Arterioscler Thromb Vasc Biol 2012; 32(7): 1613-1623. https://www.ncbi.nlm.nih.gov/pubmed/22556330
- Doring Y, Zernecke A. Plasmacytoid dendritic cells in atherosclerosis. Front Physiol 2012; 3: 230. https://www.ncbi.nlm.nih.gov/pubmed/22754539
- Egea V, Schober A, Weber C. Circulating miRNAs: messengers on the move in cardiovascular disease. Thromb Haemost 2012; 108(4): 590-591. https://www.ncbi.nlm.nih.gov/pubmed/22955179
- Egea V, Zahler S, Rieth N, Neth P, Popp T, Kehe K, Jochum M, Ries C. Tissue inhibitor of metalloproteinase-1 (TIMP-1) regulates mesenchymal stem cells through let-7f microRNA and Wnt/beta-catenin signaling. Proc Natl Acad Sci U S A 2012; 109(6): E309-316. https://www.ncbi.nlm.nih.gov/pubmed/22223664
- Faussner A, Schussler S, Feierler J, Bermudez M, Pfeifer J, Schnatbaum K, Tradler T, Jochum M, Wolber G, Gibson C. Binding characteristics of [3H]-JSM10292: a new cell membrane-permeant non-peptide bradykinin B2 receptor antagonist. Br J Pharmacol 2012; 167(4): 839-853. https://www.ncbi.nlm.nih.gov/pubmed/22646218
- Grismayer B, Sato S, Kopitz C, Ries C, Soelch S, Schmitt M, Baretton G, Kruger A, Luther T, Kotzsch M, Magdolen V. Overexpression of the urokinase receptor splice variant uPAR-del4/5 in breast cancer cells affects cell adhesion and invasion in a dose-dependent manner and modulates transcription of tumor-associated genes. Biol Chem 2012; 393(12): 1449-1455. https://www.ncbi.nlm.nih.gov/pubmed/23667902
- Grommes J, Alard JE, Drechsler M, Wantha S, Morgelin M, Kuebler WM, Jacobs M, von Hundelshausen P, Markart P, Wygrecka M, Preissner KT, Hackeng TM, Koenen RR, Weber C, Soehnlein O. Disruption of platelet-derived chemokine heteromers prevents neutrophil extravasation in acute lung injury. Am J Respir Crit Care Med 2012; 185(6): 628-636. https://www.ncbi.nlm.nih.gov/pubmed/22246174
- Grommes J, Morgelin M, Soehnlein O. Pioglitazone attenuates endotoxin-induced acute lung injury by reducing neutrophil recruitment. Eur Respir J 2012; 40(2): 416-423. https://www.ncbi.nlm.nih.gov/pubmed/22267758
- Grommes J, Vijayan S, Drechsler M, Hartwig H, Morgelin M, Dembinski R, Jacobs M, Koeppel TA, Binnebosel M, Weber C, Soehnlein O. Simvastatin reduces endotoxin-induced acute lung injury by decreasing neutrophil recruitment and radical formation. PLoS One 2012; 7(6): e38917. https://www.ncbi.nlm.nih.gov/pubmed/22701728
- Hamesch K, Subramanian P, Li X, Dembowsky K, Chevalier E, Weber C, Schober A. The CXCR4 antagonist POL5551 is equally effective as sirolimus in reducing neointima formation without impairing re-endothelialisation. Thromb Haemost 2012; 107(2): 356-368. https://www.ncbi.nlm.nih.gov/pubmed/22234341
- Hristov M, Schmitz S, Nauwelaers F, Weber C. A flow cytometric protocol for enumeration of endothelial progenitor cells and monocyte subsets in human blood. J Immunol Methods 2012; 381(1-2): 9-13. https://www.ncbi.nlm.nih.gov/pubmed/22537800
- Kamchybekov U, Figulla HR, Gerdes N, Jung C. Macrophage migration inhibitory factor is elevated in obese adolescents. Arch Physiol Biochem 2012; 118(4): 204-209. https://www.ncbi.nlm.nih.gov/pubmed/22676646
- Kanzler I, Liehn EA, Koenen RR, Weber C. Anti-inflammatory therapeutic approaches to reduce acute atherosclerotic complications. Curr Pharm Biotechnol 2012; 13(1): 37-45. https://www.ncbi.nlm.nih.gov/pubmed/21470163
- Karshovska E, Weber C. Atherosclerosis: cell biology and lipoproteins--new mechanistic links in atherosclerosis: chemokines mediating the effects of lipids, platelets and dendritic cells. Curr Opin Lipidol 2012; 23(4): 400-401. https://www.ncbi.nlm.nih.gov/pubmed/22801391
- Koenen R, Weber C. Chemokines and Their Receptors as Therapeutic Targets in Atherosclerosis. In: Atherosclerosis: Treatment and Prevention. Pan Stanford Publishing; 2012: 1-30. http://dx.doi.org/10.1201/b13723-2
- Kolben T, Perobner I, Fernsebner K, Lechner F, Geissler C, Ruiz-Heinrich L, Capovilla S, Jochum M, Neth P. Dissecting the impact of Frizzled receptors in Wnt/beta-catenin signaling of human mesenchymal stem cells. Biol Chem 2012; 393(12): 1433-1447. https://www.ncbi.nlm.nih.gov/pubmed/23152409
- Liehn EA, Bucur O, Weber C. Role of microparticles as messengers enhancing stem cell activity after genetic engineering. Circ Res 2012; 111(3): 265-267. https://www.ncbi.nlm.nih.gov/pubmed/22821904
- Lip GYH, Weber C. Welcome to a new year in Thrombosis and Haemostasis…. Thrombosis and Haemostasis 2012; 107(01): 1-2. http://dx.doi.org/10.1055/s-0037-1608982
- Lutgens E, Leiner T, Weber C. RANK(L)-ing biomarkers as surrogates for coronary calcium score. Thromb Haemost 2012; 107(1): 3. https://www.ncbi.nlm.nih.gov/pubmed/22159710
- Matusik P, Guzik B, Weber C, Guzik TJ. Do we know enough about the immune pathogenesis of acute coronary syndromes to improve clinical practice? Thromb Haemost 2012; 108(3): 443-456. https://www.ncbi.nlm.nih.gov/pubmed/22872109
- Megens RT, Vijayan S, Lievens D, Doring Y, van Zandvoort MA, Grommes J, Weber C, Soehnlein O. Presence of luminal neutrophil extracellular traps in atherosclerosis. Thromb Haemost 2012; 107(3): 597-598. https://www.ncbi.nlm.nih.gov/pubmed/22318427
- Nazari-Jahantigh M, Wei Y, Noels H, Akhtar S, Zhou Z, Koenen RR, Heyll K, Gremse F, Kiessling F, Grommes J, Weber C, Schober A. MicroRNA-155 promotes atherosclerosis by repressing Bcl6 in macrophages. J Clin Invest 2012; 122(11): 4190-4202. https://www.ncbi.nlm.nih.gov/pubmed/23041630
- Nazari-Jahantigh M, Wei Y, Schober A. The role of microRNAs in arterial remodelling. Thromb Haemost 2012; 107(4): 611-618. https://www.ncbi.nlm.nih.gov/pubmed/22371089
- Noels H, Bernhagen J, Weber C. MIF in Atherosclerosis. In: The MIF Handbook. WORLD SCIENTIFIC; 2012: 321-345. http://dx.doi.org/10.1142/9789814335362_0017
- Perobner I, Karow M, Jochum M, Neth P. LRP6 mediates Wnt/beta-catenin signaling and regulates adipogenic differentiation in human mesenchymal stem cells. Int J Biochem Cell Biol 2012; 44(11): 1970-1982. https://www.ncbi.nlm.nih.gov/pubmed/22871567
- Postea O, Vasina EM, Cauwenberghs S, Projahn D, Liehn EA, Lievens D, Theelen W, Kramp BK, Butoi ED, Soehnlein O, Heemskerk JW, Ludwig A, Weber C, Koenen RR. Contribution of platelet CX(3)CR1 to platelet-monocyte complex formation and vascular recruitment during hyperlipidemia. Arterioscler Thromb Vasc Biol 2012; 32(5): 1186-1193. https://www.ncbi.nlm.nih.gov/pubmed/22383701
- Poti F, Costa S, Bergonzini V, Galletti M, Pignatti E, Weber C, Simoni M, Nofer JR. Effect of sphingosine 1-phosphate (S1P) receptor agonists FTY720 and CYM5442 on atherosclerosis development in LDL receptor deficient (LDL-R(-)/(-)) mice. Vascul Pharmacol 2012; 57(1): 56-64. https://www.ncbi.nlm.nih.gov/pubmed/22459073
- Projahn D, Koenen RR. Platelets: key players in vascular inflammation. J Leukoc Biol 2012; 92(6): 1167-1175. https://www.ncbi.nlm.nih.gov/pubmed/22923486
- Raffetseder U, Liehn EA, Weber C, Mertens PR. Role of cold shock Y-box protein-1 in inflammation, atherosclerosis and organ transplant rejection. Eur J Cell Biol 2012; 91(6-7): 567-575. https://www.ncbi.nlm.nih.gov/pubmed/21943779
- Redondo S, Gonzalez-Rocafort A, Navarro-Dorado J, Ramajo M, Hristov M, Gordillo-Moscoso A, Reguillo F, Carnero M, Martinez-Gonzalez J, Rodriguez E, Weber C, Tejerina T. Decreased pre-surgical CD34+/CD144+ cell number in patients undergoing coronary artery bypass grafting compared to coronary artery disease-free valvular patients. J Cardiothorac Surg 2012; 7: 2. https://www.ncbi.nlm.nih.gov/pubmed/22214418
- Rohwedder I, Montanez E, Beckmann K, Bengtsson E, Duner P, Nilsson J, Soehnlein O, Fassler R. Plasma fibronectin deficiency impedes atherosclerosis progression and fibrous cap formation. EMBO Mol Med 2012; 4(7): 564-576. https://www.ncbi.nlm.nih.gov/pubmed/22514136
- Rowinska Z, Zander S, Zernecke A, Jacobs M, Langer S, Weber C, Merx MW, Koeppel TA. Non- invasive in vivo analysis of a murine aortic graft using high resolution ultrasound microimaging. Eur J Radiol 2012; 81(2): 244-249. https://www.ncbi.nlm.nih.gov/pubmed/21334152
- Schober A, Siess W. Lysophosphatidic acid in atherosclerotic diseases. Br J Pharmacol 2012; 167(3): 465-482. https://www.ncbi.nlm.nih.gov/pubmed/22568609
- Schuh A, Kroh A, Konschalla S, Liehn EA, Sobota RM, Biessen EA, Bot I, Sonmez TT, Schober A, Marx N, Weber C, Sasse A. Myocardial regeneration by transplantation of modified endothelial progenitor cells expressing SDF-1 in a rat model. J Cell Mol Med 2012; 16(10): 2311-2320. https://www.ncbi.nlm.nih.gov/pubmed/22288686
- Schuh A, Sasse A, Konschalla S, Kroh A, Merx MW, Weber C, Liehn EA. Repetitive transplantation of different cell types sequentially improves heart function after infarction. J Cell Mol Med 2012; 16(7): 1640-1647. https://www.ncbi.nlm.nih.gov/pubmed/22050647
- Schwartz V, Kruttgen A, Weis J, Weber C, Ostendorf T, Lue H, Bernhagen J. Role for CD74 and CXCR4 in clathrin-dependent endocytosis of the cytokine MIF. Eur J Cell Biol 2012; 91(6-7): 435-449. https://www.ncbi.nlm.nih.gov/pubmed/22014447
- Soehnlein O. Multiple roles for neutrophils in atherosclerosis. Circ Res 2012; 110(6): 875-888. https://www.ncbi.nlm.nih.gov/pubmed/22427325
- Soehnlein O, Weber C. Neutrophils and their granule proteins in the treatment of athero-sclerosis. In: Atherosclerosis: Treatment and Prevention. Pan Stanford Publishing; 2012: 1-30. http://dx.doi.org/10.1201/b13723-2
- Stoger JL, Gijbels MJ, van der Velden S, Manca M, van der Loos CM, Biessen EA, Daemen MJ, Lutgens E, de Winther MP. Distribution of macrophage polarization markers in human atherosclerosis. Atherosclerosis 2012; 225(2): 461-468. https://www.ncbi.nlm.nih.gov/pubmed/23078881
- Van de Vijver P, Schmitt M, Suylen D, Scheer L, Thomassen MC, Schurgers LJ, Griffin JH, Koenen RR, Hackeng TM. Incorporation of disulfide containing protein modules into multivalent antigenic conjugates: generation of antibodies against the thrombin-sensitive region of murine protein S. J Am Chem Soc 2012; 134(47): 19318-19321. https://www.ncbi.nlm.nih.gov/pubmed/23066897
- Weber C, Lip GYH. Highlights and hot topics from 2011 in Thrombosis and Haemostasis. Thrombosis and Haemostasis 2012; 107(01): 196-199. http://dx.doi.org/10.1055/s-0037-1608981
- Zernecke A, Weber C. Improving the treatment of atherosclerosis by linking anti-inflammatory and lipid modulating strategies. Heart 2012; 98(21): 1600-1606. https://www.ncbi.nlm.nih.gov/pubmed/23086996
- Bampalis VG, Dwivedi S, Shai E, Brandl R, Varon D, Siess W. Effect of 5-HT2A receptor antagonists on human platelet activation in blood exposed to physiologic stimuli and atherosclerotic plaque. J Thromb Haemost 2011; 9(10): 2112-2115. https://www.ncbi.nlm.nih.gov/pubmed/21848639
- Butoi ED, Gan AM, Manduteanu I, Stan D, Calin M, Pirvulescu M, Koenen RR, Weber C, Simionescu M. Cross talk between smooth muscle cells and monocytes/activated monocytes via CX3CL1/CX3CR1 axis augments expression of pro-atherogenic molecules. Biochim Biophys Acta 2011; 1813(12): 2026-2035. https://www.ncbi.nlm.nih.gov/pubmed/21888931
- Daissormont IT, Christ A, Temmerman L, Sampedro Millares S, Seijkens T, Manca M, Rousch M, Poggi M, Boon L, van der Loos C, Daemen M, Lutgens E, Halvorsen B, Aukrust P, Janssen E, Biessen EA. Plasmacytoid dendritic cells protect against atherosclerosis by tuning T-cell proliferation and activity. Circ Res 2011; 109(12): 1387-1395. https://www.ncbi.nlm.nih.gov/pubmed/22021930
- de Jager SC, Bermudez B, Bot I, Koenen RR, Bot M, Kavelaars A, de Waard V, Heijnen CJ, Muriana FJ, Weber C, van Berkel TJ, Kuiper J, Lee SJ, Abia R, Biessen EA. Growth differentiation factor 15 deficiency protects against atherosclerosis by attenuating CCR2-mediated macrophage chemotaxis. J Exp Med 2011; 208(2): 217-225. https://www.ncbi.nlm.nih.gov/pubmed/21242297
- Douma K, Megens RT, van Zandvoort MA. Optical molecular imaging of atherosclerosis using nanoparticles: shedding new light on the darkness. Wiley Interdiscip Rev Nanomed Nanobiotechnol 2011; 3(4): 376-388. https://www.ncbi.nlm.nih.gov/pubmed/21448988
- Drechsler M, Doring Y, Megens RT, Soehnlein O. Neutrophilic granulocytes - promiscuous accelerators of atherosclerosis. Thromb Haemost 2011; 106(5): 839-848. https://www.ncbi.nlm.nih.gov/pubmed/22012406
- Engel D, Beckers L, Wijnands E, Seijkens T, Lievens D, Drechsler M, Gerdes N, Soehnlein O, Daemen MJ, Stan RV, Biessen EA, Lutgens E. Caveolin-1 deficiency decreases atherosclerosis by hampering leukocyte influx into the arterial wall and generating a regulatory T-cell response. FASEB J 2011; 25(11): 3838-3848. https://www.ncbi.nlm.nih.gov/pubmed/21795505
- Frithiof R, Soehnlein O, Eriksson S, Fenhammar J, Hjelmqvist H, Lindbom L, Rundgren M. The effects of isoflurane anesthesia and mechanical ventilation on renal function during endotoxemia. Acta Anaesthesiol Scand 2011; 55(4): 401-410. https://www.ncbi.nlm.nih.gov/pubmed/21391922
- Gerdes N, Zhu L, Ersoy M, Hermansson A, Hjemdahl P, Hu H, Hansson GK, Li N. Platelets regulate CD4(+) T-cell differentiation via multiple chemokines in humans. Thromb Haemost 2011; 106(2): 353-362. https://www.ncbi.nlm.nih.gov/pubmed/21655676
- Gerdes N, Zirlik A. Co-stimulatory molecules in and beyond co-stimulation - tipping the balance in atherosclerosis? Thromb Haemost 2011; 106(5): 804-813. https://www.ncbi.nlm.nih.gov/pubmed/21979444
- Goyal P, Behring A, Kumar A, Siess W. STK35L1 associates with nuclear actin and regulates cell cycle and migration of endothelial cells. PLoS One 2011; 6(1): e16249. https://www.ncbi.nlm.nih.gov/pubmed/21283756
- Grommes J, Soehnlein O. Contribution of neutrophils to acute lung injury. Mol Med 2011; 17(3-4): 293-307. https://www.ncbi.nlm.nih.gov/pubmed/21046059
- Heinrichs D, Knauel M, Offermanns C, Berres ML, Nellen A, Leng L, Schmitz P, Bucala R, Trautwein C, Weber C, Bernhagen J, Wasmuth HE. Macrophage migration inhibitory factor (MIF) exerts antifibrotic effects in experimental liver fibrosis via CD74. Proc Natl Acad Sci U S A 2011; 108(42): 17444-17449. https://www.ncbi.nlm.nih.gov/pubmed/21969590
- Hristov M, Weber C. Differential role of monocyte subsets in atherosclerosis. Thromb Haemost 2011; 106(5): 757-762. https://www.ncbi.nlm.nih.gov/pubmed/21901241
- Khandoga AL, Pandey D, Welsch U, Brandl R, Siess W. GPR92/LPA(5) lysophosphatidate receptor mediates megakaryocytic cell shape change induced by human atherosclerotic plaques. Cardiovasc Res 2011; 90(1): 157-164. https://www.ncbi.nlm.nih.gov/pubmed/21106562
- Koenen RR, Weber C. Chemokines: established and novel targets in atherosclerosis. EMBO Mol Med 2011; 3(12): 713-725. https://www.ncbi.nlm.nih.gov/pubmed/22038924
- Kraemer S, Lue H, Zernecke A, Kapurniotu A, Andreetto E, Frank R, Lennartz B, Weber C, Bernhagen J. MIF-chemokine receptor interactions in atherogenesis are dependent on an N-loop-based 2-site binding mechanism. FASEB J 2011; 25(3): 894-906. https://www.ncbi.nlm.nih.gov/pubmed/21106938
- Kramp BK, Sarabi A, Koenen RR, Weber C. Heterophilic chemokine receptor interactions in chemokine signaling and biology. Exp Cell Res 2011; 317(5): 655-663. https://www.ncbi.nlm.nih.gov/pubmed/21146524
- Kuijpers MJ, Megens RT, Nikookhesal E, Feijge MA, De Mey JG, oude Egbrink MG, van Giezen JJ, Heemskerk JW. Role of newly formed platelets in thrombus formation in rat after clopidogrel treatment: comparison to the reversible binding P2Y(1)(2) antagonist ticagrelor. Thromb Haemost 2011; 106(6): 1179-1188. https://www.ncbi.nlm.nih.gov/pubmed/22071958
- Liehn EA, Tuchscheerer N, Kanzler I, Drechsler M, Fraemohs L, Schuh A, Koenen RR, Zander S, Soehnlein O, Hristov M, Grigorescu G, Urs AO, Leabu M, Bucur I, Merx MW, Zernecke A, Ehling J, Gremse F, Lammers T, Kiessling F, Bernhagen J, Schober A, Weber C. Double-edged role of the CXCL12/CXCR4 axis in experimental myocardial infarction. J Am Coll Cardiol 2011; 58(23): 2415-2423. https://www.ncbi.nlm.nih.gov/pubmed/22115649
- Lievens D, von Hundelshausen P. Platelets in atherosclerosis. Thromb Haemost 2011; 106(5): 827-838. https://www.ncbi.nlm.nih.gov/pubmed/22012554
- Lip GY, Weber C. Clinical and basic science articles from Thrombosis and Haemostasis. Thromb Haemost 2011; 105(1): 202-205. https://www.ncbi.nlm.nih.gov/pubmed/21249716
- Lutgens E, Binder CJ. Immunology of atherosclerosis. Thromb Haemost 2011; 106(5): 755-756. https://www.ncbi.nlm.nih.gov/pubmed/22011700
- Megens RT, Kemmerich K, Pyta J, Weber C, Soehnlein O. Intravital imaging of phagocyte recruitment. Thromb Haemost 2011; 105(5): 802-810. https://www.ncbi.nlm.nih.gov/pubmed/21437362
- Megens RT, Soehnlein O. Seeing is believing: an update on modalities to image inflammation in vivo. Thromb Haemost 2011; 105(5): 774-775. https://www.ncbi.nlm.nih.gov/pubmed/21437354
- Noels H, Weber C. Catching up with important players in atherosclerosis: type I interferons and neutrophils. Curr Opin Lipidol 2011; 22(2): 144-145. https://www.ncbi.nlm.nih.gov/pubmed/21415605
- Poggi M, Engel D, Christ A, Beckers L, Wijnands E, Boon L, Driessen A, Cleutjens J, Weber C, Gerdes N, Lutgens E. CD40L deficiency ameliorates adipose tissue inflammation and metabolic manifestations of obesity in mice. Arterioscler Thromb Vasc Biol 2011; 31(10): 2251-2260. https://www.ncbi.nlm.nih.gov/pubmed/21817098
- Rana OR, Saygili E, Gemein C, Zink MD, Buhr A, Saygili E, Mischke K, Nolte KW, Weis J, Weber C, Marx N, Schauerte P. Chronic electrical neuronal stimulation increases cardiac parasympathetic tone by eliciting neurotrophic effects. Circ Res 2011; 108(10): 1209-1219. https://www.ncbi.nlm.nih.gov/pubmed/21441135
- Reitsma S, Oude Egbrink MG, Heijnen VV, Megens RT, Engels W, Vink H, Slaaf DW, van Zandvoort MA. Endothelial glycocalyx thickness and platelet-vessel wall interactions during atherogenesis. Thromb Haemost 2011; 106(5): 939-946. https://www.ncbi.nlm.nih.gov/pubmed/21901228
- Sarabi A, Kramp BK, Drechsler M, Hackeng TM, Soehnlein O, Weber C, Koenen RR, Von Hundelshausen P. CXCL4L1 inhibits angiogenesis and induces undirected endothelial cell migration without affecting endothelial cell proliferation and monocyte recruitment. J Thromb Haemost 2011; 9(1): 209-219. https://www.ncbi.nlm.nih.gov/pubmed/20961394
- Saygili E, Schauerte P, Pekassa M, Saygili E, Rackauskas G, Schwinger RH, Weis J, Weber C, Marx N, Rana OR. Sympathetic neurons express and secrete MMP-2 and MT1-MMP to control nerve sprouting via pro-NGF conversion. Cell Mol Neurobiol 2011; 31(1): 17-25. https://www.ncbi.nlm.nih.gov/pubmed/20683769
- Schober A, Hristov M, Kofler S, Forbrig R, Lohr B, Heussen N, Zhe Z, Akhtar S, Schumann U, Krotz F, Leibig M, Konig A, Kaczmarek I, Reichart B, Klauss V, Weber C, Sohn HY. CD34+CD140b+ cells and circulating CXCL12 correlate with the angiographically assessed severity of cardiac allograft vasculopathy. Eur Heart J 2011; 32(4): 476-484. https://www.ncbi.nlm.nih.gov/pubmed/21036775
- Schober A, Weber C. Bone marrow-derived smooth muscle cells are breaking bad in atherogenesis. Arterioscler Thromb Vasc Biol 2011; 31(6): 1258-1259. https://www.ncbi.nlm.nih.gov/pubmed/21593459
- Schober LJ, Khandoga AL, Dwivedi S, Penz SM, Maruyama T, Brandl R, Siess W. The role of PGE(2) in human atherosclerotic plaque on platelet EP(3) and EP(4) receptor activation and platelet function in whole blood. J Thromb Thrombolysis 2011; 32(2): 158-166. https://www.ncbi.nlm.nih.gov/pubmed/21424266
- Simons D, Grieb G, Hristov M, Pallua N, Weber C, Bernhagen J, Steffens G. Hypoxia-induced endothelial secretion of macrophage migration inhibitory factor and role in endothelial progenitor cell recruitment. J Cell Mol Med 2011; 15(3): 668-678. https://www.ncbi.nlm.nih.gov/pubmed/20178462
- Soehnlein O, Wantha S, Simsekyilmaz S, Doring Y, Megens RT, Mause SF, Drechsler M, Smeets R, Weinandy S, Schreiber F, Gries T, Jockenhoevel S, Moller M, Vijayan S, van Zandvoort MA, Agerberth B, Pham CT, Gallo RL, Hackeng TM, Liehn EA, Zernecke A, Klee D, Weber C. Neutrophil-derived cathelicidin protects from neointimal hyperplasia. Sci Transl Med 2011; 3(103): 103ra198. https://www.ncbi.nlm.nih.gov/pubmed/21974936
- Vasina EM, Cauwenberghs S, Feijge MA, Heemskerk JW, Weber C, Koenen RR. Microparticles from apoptotic platelets promote resident macrophage differentiation. Cell Death Dis 2011; 2(9): e211. https://www.ncbi.nlm.nih.gov/pubmed/21956548
- Vonend O, Ockenfels N, Gao X, Allolio B, Lang K, Mai K, Quack I, Saleh A, Degenhart C, Seufert J, Seiler L, Beuschlein F, Quinkler M, Podrabsky P, Bidlingmaier M, Lorenz R, Reincke M, Rump LC, German Conn's R. Adrenal venous sampling: evaluation of the German Conn's registry. Hypertension 2011; 57(5): 990-995. https://www.ncbi.nlm.nih.gov/pubmed/21383311
- Weber C, Lip G. Commencing 2011 with Thrombosis and Haemostasis – and looking to the future. Thrombosis and Haemostasis 2011; 105(01): 1-2. http://dx.doi.org/10.1055/s-0037-1609003
- Weber C, Meiler S, Doring Y, Koch M, Drechsler M, Megens RT, Rowinska Z, Bidzhekov K, Fecher C, Ribechini E, van Zandvoort MA, Binder CJ, Jelinek I, Hristov M, Boon L, Jung S, Korn T, Lutz MB, Forster I, Zenke M, Hieronymus T, Junt T, Zernecke A. CCL17-expressing dendritic cells drive atherosclerosis by restraining regulatory T cell homeostasis in mice. J Clin Invest 2011; 121(7): 2898-2910. https://www.ncbi.nlm.nih.gov/pubmed/21633167
- Weber C, Noels H. Atherosclerosis: current pathogenesis and therapeutic options. Nat Med 2011; 17(11): 1410-1422. https://www.ncbi.nlm.nih.gov/pubmed/22064431
- Weber C, Soehnlein O. ApoE controls the interface linking lipids and inflammation in atherosclerosis. J Clin Invest 2011; 121(10): 3825-3827. https://www.ncbi.nlm.nih.gov/pubmed/21968109
- Wildhagen KC, Lutgens E, Loubele ST, ten Cate H, Nicolaes GA. The structure-function relationship of activated protein C. Lessons from natural and engineered mutations. Thromb Haemost 2011; 106(6): 1034-1045. https://www.ncbi.nlm.nih.gov/pubmed/22072231
- Yla-Herttuala S, Bentzon JF, Daemen M, Falk E, Garcia-Garcia HM, Herrmann J, Hoefer I, Jukema JW, Krams R, Kwak BR, Marx N, Naruszewicz M, Newby A, Pasterkamp G, Serruys PW, Waltenberger J, Weber C, Tokgozoglu L. Stabilisation of atherosclerotic plaques. Position paper of the European Society of Cardiology (ESC) Working Group on atherosclerosis and vascular biology. Thromb Haemost 2011; 106(1): 1-19. https://www.ncbi.nlm.nih.gov/pubmed/21670845
- Zhou Z, Subramanian P, Sevilmis G, Globke B, Soehnlein O, Karshovska E, Megens R, Heyll K, Chun J, Saulnier-Blache JS, Reinholz M, van Zandvoort M, Weber C, Schober A. Lipoprotein-derived lysophosphatidic acid promotes atherosclerosis by releasing CXCL1 from the endothelium. Cell Metab 2011; 13(5): 592-600. https://www.ncbi.nlm.nih.gov/pubmed/21531341
- Bai L, Beckers L, Wijnands E, Lutgens SP, Herias MV, Saftig P, Daemen MJ, Cleutjens K, Lutgens E, Biessen EA, Heeneman S. Cathepsin K gene disruption does not affect murine aneurysm formation. Atherosclerosis 2010; 209(1): 96-103. https://www.ncbi.nlm.nih.gov/pubmed/19775691
- Bampalis VG, Khandoga AL, Siess W. Fluoxetine inhibition of 5-HT-potentiated platelet aggregation in whole blood. Thromb Haemost 2010; 104(6): 1272-4. https://www.ncbi.nlm.nih.gov/pubmed/20806122
- Berres ML, Koenen RR, Rueland A, Zaldivar MM, Heinrichs D, Sahin H, Schmitz P, Streetz KL, Berg T, Gassler N, Weiskirchen R, Proudfoot A, Weber C, Trautwein C, Wasmuth HE. Antagonism of the chemokine Ccl5 ameliorates experimental liver fibrosis in mice. J Clin Invest 2010; 120(11): 4129-40. https://www.ncbi.nlm.nih.gov/pubmed/20978355
- Braunersreuther V, Pellieux C, Pelli G, Burger F, Steffens S, Montessuit C, Weber C, Proudfoot A, Mach F, Arnaud C. Chemokine CCL5/RANTES inhibition reduces myocardial reperfusion injury in atherosclerotic mice. J Mol Cell Cardiol 2010; 48(4): 789-98. https://www.ncbi.nlm.nih.gov/pubmed/19665464
- Drechsler M, Megens RT, van Zandvoort M, Weber C, Soehnlein O. Hyperlipidemia-triggered neutrophilia promotes early atherosclerosis. Circulation 2010; 122(18): 1837-45. https://www.ncbi.nlm.nih.gov/pubmed/20956207
- Dwivedi S, Pandey D, Khandoga AL, Brandl R, Siess W. Rac1-mediated signaling plays a central role in secretion-dependent platelet aggregation in human blood stimulated by atherosclerotic plaque. J Transl Med 2010; 8: 128. https://www.ncbi.nlm.nih.gov/pubmed/21134286
- Felker P, Sere K, Lin Q, Becker C, Hristov M, Hieronymus T, Zenke M. TGF-beta1 accelerates dendritic cell differentiation from common dendritic cell progenitors and directs subset specification toward conventional dendritic cells. J Immunol 2010; 185(9): 5326-35. https://www.ncbi.nlm.nih.gov/pubmed/20881193
- Gerdes N. From bystander to commander: how smooth muscle cells promote lymphoid tissue neogenesis. Arterioscler Thromb Vasc Biol 2010; 30(3): 393-4. https://www.ncbi.nlm.nih.gov/pubmed/20139359
- Goossens P, Gijbels MJ, Zernecke A, Eijgelaar W, Vergouwe MN, van der Made I, Vanderlocht J, Beckers L, Buurman WA, Daemen MJ, Kalinke U, Weber C, Lutgens E, de Winther MP. Myeloid type I interferon signaling promotes atherosclerosis by stimulating macrophage recruitment to lesions. Cell Metab 2010; 12(2): 142-53. https://www.ncbi.nlm.nih.gov/pubmed/20674859
- Hristov M, Gumbel D, Lutgens E, Zernecke A, Weber C. Soluble CD40 ligand impairs the function of peripheral blood angiogenic outgrowth cells and increases neointimal formation after arterial injury. Circulation 2010; 121(2): 315-24. https://www.ncbi.nlm.nih.gov/pubmed/20048211
- Hristov M, Leyendecker T, Schuhmann C, von Hundelshausen P, Heussen N, Kehmeier E, Krotz F, Sohn HY, Klauss V, Weber C. Circulating monocyte subsets and cardiovascular risk factors in coronary artery disease. Thromb Haemost 2010; 104(2): 412-4. https://www.ncbi.nlm.nih.gov/pubmed/20431842
- Jung C, Gerdes N, Fritzenwanger M, Figulla HR. Circulating levels of interleukin-1 family cytokines in overweight adolescents. Mediators Inflamm 2010; 2010: 958403. https://www.ncbi.nlm.nih.gov/pubmed/20169140
- Kenne E, Soehnlein O, Genove G, Rotzius P, Eriksson EE, Lindbom L. Immune cell recruitment to inflammatory loci is impaired in mice deficient in basement membrane protein laminin alpha4. J Leukoc Biol 2010; 88(3): 523-8. https://www.ncbi.nlm.nih.gov/pubmed/20483922
- Koenen RR, Weber C. Therapeutic targeting of chemokine interactions in atherosclerosis. Nat Rev Drug Discov 2010; 9(2): 141-53. https://www.ncbi.nlm.nih.gov/pubmed/20118962
- Koenen RR, Weber C. Platelet-derived chemokines in vascular remodeling and atherosclerosis. Semin Thromb Hemost 2010; 36(2): 163-9. https://www.ncbi.nlm.nih.gov/pubmed/20414831
- Liehn EA, Piccinini AM, Koenen RR, Soehnlein O, Adage T, Fatu R, Curaj A, Popescu A, Zernecke A, Kungl AJ, Weber C. A new monocyte chemotactic protein-1/chemokine CC motif ligand-2 competitor limiting neointima formation and myocardial ischemia/reperfusion injury in mice. J Am Coll Cardiol 2010; 56(22): 1847-57. https://www.ncbi.nlm.nih.gov/pubmed/21087715
- Lievens D, Gerdes N, Schober A, Weber C. Atherosclerosis: cell biology and lipoproteins. Curr Opin Lipidol 2010; 21(3): 284-5. https://www.ncbi.nlm.nih.gov/pubmed/20463476
- Lievens D, Zernecke A, Seijkens T, Soehnlein O, Beckers L, Munnix IC, Wijnands E, Goossens P, van Kruchten R, Thevissen L, Boon L, Flavell RA, Noelle RJ, Gerdes N, Biessen EA, Daemen MJ, Heemskerk JW, Weber C, Lutgens E. Platelet CD40L mediates thrombotic and inflammatory processes in atherosclerosis. Blood 2010; 116(20): 4317-27. https://www.ncbi.nlm.nih.gov/pubmed/20705757
- Linder A, Soehnlein O, Akesson P. Roles of heparin-binding protein in bacterial infections. J Innate Immun 2010; 2(5): 431-8. https://www.ncbi.nlm.nih.gov/pubmed/20505311
- Loges S, Schmidt T, Tjwa M, van Geyte K, Lievens D, Lutgens E, Vanhoutte D, Borgel D, Plaisance S, Hoylaerts M, Luttun A, Dewerchin M, Jonckx B, Carmeliet P. Malignant cells fuel tumor growth by educating infiltrating leukocytes to produce the mitogen Gas6. Blood 2010; 115(11): 2264-73. https://www.ncbi.nlm.nih.gov/pubmed/19965679
- Lutgens E, Lievens D, Beckers L, Wijnands E, Soehnlein O, Zernecke A, Seijkens T, Engel D, Cleutjens J, Keller AM, Naik SH, Boon L, Oufella HA, Mallat Z, Ahonen CL, Noelle RJ, de Winther MP, Daemen MJ, Biessen EA, Weber C. Deficient CD40-TRAF6 signaling in leukocytes prevents atherosclerosis by skewing the immune response toward an antiinflammatory profile. J Exp Med 2010; 207(2): 391-404. https://www.ncbi.nlm.nih.gov/pubmed/20100871
- Mause SF, Ritzel E, Liehn EA, Hristov M, Bidzhekov K, Muller-Newen G, Soehnlein O, Weber C. Platelet microparticles enhance the vasoregenerative potential of angiogenic early outgrowth cells after vascular injury. Circulation 2010; 122(5): 495-506. https://www.ncbi.nlm.nih.gov/pubmed/20644015
- Mause SF, Weber C. Microparticles: protagonists of a novel communication network for intercellular information exchange. Circ Res 2010; 107(9): 1047-57. https://www.ncbi.nlm.nih.gov/pubmed/21030722
- Mause SF, Weber C, Sampol J, Dignat-George F. New horizons in vascular biology and thrombosis: Highlights from EMVBM 2009. Thromb Haemost 2010; 104(3): 421-3. https://www.ncbi.nlm.nih.gov/pubmed/20694282
- Meuwese MC, Broekhuizen LN, Kuikhoven M, Heeneman S, Lutgens E, Gijbels MJ, Nieuwdorp M, Peutz CJ, Stroes ES, Vink H, van den Berg BM. Endothelial surface layer degradation by chronic hyaluronidase infusion induces proteinuria in apolipoprotein E-deficient mice. PLoS One 2010; 5(12): e14262. https://www.ncbi.nlm.nih.gov/pubmed/21170388
- Noels H, Weber C. Fractalkine as an important target of aspirin in the prevention of atherogenesis : Editorial to: "Aspirin inhibits fractalkine expression in atherosclerotic plaques and reduces atherosclerosis in ApoE gene knockout mice" by H. Liu et al. Cardiovasc Drugs Ther 2010; 24(1): 1-3. https://www.ncbi.nlm.nih.gov/pubmed/20033269
- Penz SM, Bernlochner I, Toth O, Lorenz R, Calatzis A, Siess W. Selective and rapid monitoring of dual platelet inhibition by aspirin and P2Y12 antagonists by using multiple electrode aggregometry. Thromb J 2010; 8: 9. https://www.ncbi.nlm.nih.gov/pubmed/20465804
- Preissner K, Lip G, Weber C. Editor´s choice articles 2008–2009. Thrombosis and Haemostasis 2017; 103(01): 3-6. http://dx.doi.org/10.1055/s-0037-1608916
- Rana OR, Schauerte P, Kluttig R, Schroder JW, Koenen RR, Weber C, Nolte KW, Weis J, Hoffmann R, Marx N, Saygili E. Acetylcholine as an age-dependent non-neuronal source in the heart. Auton Neurosci 2010; 156(1-2): 82-9. https://www.ncbi.nlm.nih.gov/pubmed/20510655
- Reininger AJ, Bernlochner I, Penz SM, Ravanat C, Smethurst P, Farndale RW, Gachet C, Brandl R, Siess W. A 2-step mechanism of arterial thrombus formation induced by human atherosclerotic plaques. J Am Coll Cardiol 2010; 55(11): 1147-58. https://www.ncbi.nlm.nih.gov/pubmed/20223370
- Ren M, Guo Q, Guo L, Lenz M, Qian F, Koenen RR, Xu H, Schilling AB, Weber C, Ye RD, Dinner AR, Tang WJ. Polymerization of MIP-1 chemokine (CCL3 and CCL4) and clearance of MIP-1 by insulin-degrading enzyme. EMBO J 2010; 29(23): 3952-66. https://www.ncbi.nlm.nih.gov/pubmed/20959807
- Rotzius P, Thams S, Soehnlein O, Kenne E, Tseng CN, Bjorkstrom NK, Malmberg KJ, Lindbom L, Eriksson EE. Distinct infiltration of neutrophils in lesion shoulders in ApoE-/- mice. Am J Pathol 2010; 177(1): 493-500. https://www.ncbi.nlm.nih.gov/pubmed/20472897
- Saygili E, Schauerte P, Kuppers F, Heck L, Weis J, Weber C, Schwinger RH, Hoffmann R, Schroder JW, Marx N, Rana OR. Electrical stimulation of sympathetic neurons induces autocrine/paracrine effects of NGF mediated by TrkA. J Mol Cell Cardiol 2010; 49(1): 79-87. https://www.ncbi.nlm.nih.gov/pubmed/20138055
- Schober LJ, Khandoga AL, Penz SM, Siess W. The EP3-agonist sulprostone, but not prostaglandin E2 potentiates platelet aggregation in human blood. Thromb Haemost 2010; 103(6): 1268-9. https://www.ncbi.nlm.nih.gov/pubmed/20431854
- Schreinemachers MC, Doorschodt BM, Florquin S, van den Bergh Weerman MA, Zernecke A, Idu MM, Tolba RH, van Gulik TM. Pulsatile perfusion preservation of warm ischaemia-damaged experimental kidney grafts. Br J Surg 2010; 97(3): 349-58. https://www.ncbi.nlm.nih.gov/pubmed/20095019
- Schwarz N, Pruessmeyer J, Hess FM, Dreymueller D, Pantaler E, Koelsch A, Windoffer R, Voss M, Sarabi A, Weber C, Sechi AS, Uhlig S, Ludwig A. Requirements for leukocyte transmigration via the transmembrane chemokine CX3CL1. Cell Mol Life Sci 2010; 67(24): 4233-48. https://www.ncbi.nlm.nih.gov/pubmed/20559678
- Seijkens T, Engel D, Tjwa M, Lutgens E. The role of CD154 in haematopoietic development. Thromb Haemost 2010; 104(4): 693-701. https://www.ncbi.nlm.nih.gov/pubmed/20694278
- Shagdarsuren E, Bidzhekov K, Mause SF, Simsekyilmaz S, Polakowski T, Hawlisch H, Gessner JE, Zernecke A, Weber C. C5a receptor targeting in neointima formation after arterial injury in atherosclerosis-prone mice. Circulation 2010; 122(10): 1026-36. https://www.ncbi.nlm.nih.gov/pubmed/20733098
- Soehnlein O, Eriksson S, Hjelmqvist H, Andersson A, Morgelin M, Lindbom L, Rundgren M, Frithiof R. Anesthesia aggravates lung damage and precipitates hypotension in endotoxemic sheep. Shock 2010; 34(4): 412-9. https://www.ncbi.nlm.nih.gov/pubmed/20844413
- Soehnlein O, Lindbom L. Phagocyte partnership during the onset and resolution of inflammation. Nat Rev Immunol 2010; 10(6): 427-39. https://www.ncbi.nlm.nih.gov/pubmed/20498669
- Subramanian P, Karshovska E, Reinhard P, Megens RT, Zhou Z, Akhtar S, Schumann U, Li X, van Zandvoort M, Ludin C, Weber C, Schober A. Lysophosphatidic acid receptors LPA1 and LPA3 promote CXCL12-mediated smooth muscle progenitor cell recruitment in neointima formation. Circ Res 2010; 107(1): 96-105. https://www.ncbi.nlm.nih.gov/pubmed/20360252
- Subramanian P, Schober A. Neointima formation after vascular injury: is it all about CD39? Thromb Haemost 2010; 103(2): 257-8. https://www.ncbi.nlm.nih.gov/pubmed/20076840
- van Triest HJ, Megens RT, van Assen HC, ter Haar Romeny BM, van Zandvoort MA. Arterial radius estimation from microscopic data using a new algorithm for circle parameter estimation. J Biomed Opt 2010; 15(2): 026012. https://www.ncbi.nlm.nih.gov/pubmed/20459257
- Vasina E, Heemskerk JW, Weber C, Koenen RR. Platelets and platelet-derived microparticles in vascular inflammatory disease. Inflamm Allergy Drug Targets 2010; 9(5): 346-54. https://www.ncbi.nlm.nih.gov/pubmed/21054257
- Weber C. Far from the heart: Receptor cross-talk in remote conditioning. Nat Med 2010; 16(7): 760-2. https://www.ncbi.nlm.nih.gov/pubmed/20613755
- Weber C. Obstacles and options in the quest for drug candidates against vascular disease. Thromb Haemost 2010; 104(1): 1-3. https://www.ncbi.nlm.nih.gov/pubmed/20508900
- Weber C, Lip GY. Moving forward with a new editorial team for Thrombosis and Haemostasis. Thromb Haemost 2010; 103(1): 1-2. https://www.ncbi.nlm.nih.gov/pubmed/20062942
- Weber C, Schober A, Zernecke A. MicroRNAs in arterial remodelling, inflammation and atherosclerosis. Curr Drug Targets 2010; 11(8): 950-6. https://www.ncbi.nlm.nih.gov/pubmed/20415650
- Wiesner C, Faix J, Himmel M, Bentzien F, Linder S. KIF5B and KIF3A/KIF3B kinesins drive MT1-MMP surface exposure, CD44 shedding, and extracellular matrix degradation in primary macrophages. Blood 2010; 116(9): 1559-69. https://www.ncbi.nlm.nih.gov/pubmed/20505159
- Zaldivar MM, Pauels K, von Hundelshausen P, Berres ML, Schmitz P, Bornemann J, Kowalska MA, Gassler N, Streetz KL, Weiskirchen R, Trautwein C, Weber C, Wasmuth HE. CXC chemokine ligand 4 (Cxcl4) is a platelet-derived mediator of experimental liver fibrosis. Hepatology 2010; 51(4): 1345-53. https://www.ncbi.nlm.nih.gov/pubmed/20162727
- Zernecke A, Weber C. Chemokines in the vascular inflammatory response of atherosclerosis. Cardiovasc Res 2010; 86(2): 192-201. https://www.ncbi.nlm.nih.gov/pubmed/20007309
- Zimmermann HW, Seidler S, Nattermann J, Gassler N, Hellerbrand C, Zernecke A, Tischendorf JJ, Luedde T, Weiskirchen R, Trautwein C, Tacke F. Functional contribution of elevated circulating and hepatic non-classical CD14CD16 monocytes to inflammation and human liver fibrosis. PLoS One 2010; 5(6): e11049. https://www.ncbi.nlm.nih.gov/pubmed/20548789
- Doorschodt BM, Schreinemachers MC, Florquin S, Lai W, Sitzia M, Zernecke A, Tolba RH. Evaluation of a novel system for hypothermic oxygenated pulsatile perfusion preservation. Int J Artif Organs 2009; 32(10): 728-738. https://www.ncbi.nlm.nih.gov/pubmed/19943234
- Goetzenich A, Hatam N, Zernecke A, Weber C, Czarnotta T, Autschbach R, Christiansen S. Alteration of matrix metalloproteinases in selective left ventricular adriamycin-induced cardiomyopathy in the pig. J Heart Lung Transplant 2009; 28(10): 1087-1093. https://www.ncbi.nlm.nih.gov/pubmed/19782292
- Hristov M, Schmitz S, Schuhmann C, Leyendecker T, von Hundelshausen P, Krotz F, Sohn HY, Nauwelaers FA, Weber C. An optimized flow cytometry protocol for analysis of angiogenic monocytes and endothelial progenitor cells in peripheral blood. Cytometry A 2009; 75(10): 848-853. https://www.ncbi.nlm.nih.gov/pubmed/19739088
- Hristov M, Weber C. Progenitor cell trafficking in the vascular wall. J Thromb Haemost 2009; 7 Suppl 1: 31-34. https://www.ncbi.nlm.nih.gov/pubmed/19630763
- Karlmark KR, Weiskirchen R, Zimmermann HW, Gassler N, Ginhoux F, Weber C, Merad M, Luedde T, Trautwein C, Tacke F. Hepatic recruitment of the inflammatory Gr1+ monocyte subset upon liver injury promotes hepatic fibrosis. Hepatology 2009; 50(1): 261-274. https://www.ncbi.nlm.nih.gov/pubmed/19554540
- Koenen RR, Pruessmeyer J, Soehnlein O, Fraemohs L, Zernecke A, Schwarz N, Reiss K, Sarabi A, Lindbom L, Hackeng TM, Weber C, Ludwig A. Regulated release and functional modulation of junctional adhesion molecule A by disintegrin metalloproteinases. Blood 2009; 113(19): 4799-4809. https://www.ncbi.nlm.nih.gov/pubmed/19258599
- Koenen RR, von Hundelshausen P, Nesmelova IV, Zernecke A, Liehn EA, Sarabi A, Kramp BK, Piccinini AM, Paludan SR, Kowalska MA, Kungl AJ, Hackeng TM, Mayo KH, Weber C. Disrupting functional interactions between platelet chemokines inhibits atherosclerosis in hyperlipidemic mice. Nat Med 2009; 15(1): 97-103. https://www.ncbi.nlm.nih.gov/pubmed/19122657
- Landsman L, Bar-On L, Zernecke A, Kim KW, Krauthgamer R, Shagdarsuren E, Lira SA, Weissman IL, Weber C, Jung S. CX3CR1 is required for monocyte homeostasis and atherogenesis by promoting cell survival. Blood 2009; 113(4): 963-972. https://www.ncbi.nlm.nih.gov/pubmed/18971423
- Lievens D, Eijgelaar WJ, Biessen EA, Daemen MJ, Lutgens E. The multi-functionality of CD40L and its receptor CD40 in atherosclerosis. Thromb Haemost 2009; 102(2): 206-214. https://www.ncbi.nlm.nih.gov/pubmed/19652870
- Malycha F, Eggermann T, Hristov M, Schena FP, Mertens PR, Zerres K, Floege J, Eitner F. No evidence for a role of cosmc-chaperone mutations in European IgA nephropathy patients. Nephrol Dial Transplant 2009; 24(1): 321-324. https://www.ncbi.nlm.nih.gov/pubmed/18840896
- Matthijsen RA, de Winther MP, Kuipers D, van der Made I, Weber C, Herias MV, Gijbels MJ, Buurman WA. Macrophage-specific expression of mannose-binding lectin controls atherosclerosis in low-density lipoprotein receptor-deficient mice. Circulation 2009; 119(16): 2188-2195. https://www.ncbi.nlm.nih.gov/pubmed/19380618
- Mause SF, Weber C. Intrusion through the fragile back door: immature plaque microvessels as entry portals for leukocytes and erythrocytes in atherosclerosis. J Am Coll Cardiol 2009; 53(17): 1528-1531. https://www.ncbi.nlm.nih.gov/pubmed/19389563
- Noels H, Bernhagen J, Weber C. Macrophage migration inhibitory factor: a noncanonical chemokine important in atherosclerosis. Trends Cardiovasc Med 2009; 19(3): 76-86. https://www.ncbi.nlm.nih.gov/pubmed/19679264
- Noels H, Somers R, Liu H, Ye H, Du MQ, De Wolf-Peeters C, Marynen P, Baens M. Auto-ubiquitination-induced degradation of MALT1-API2 prevents BCL10 destabilization in t(11;18)(q21;q21)-positive MALT lymphoma. PLoS One 2009; 4(3): e4822. https://www.ncbi.nlm.nih.gov/pubmed/19279678
- Quast T, Tappertzhofen B, Schild C, Grell J, Czeloth N, Forster R, Alon R, Fraemohs L, Dreck K, Weber C, Lammermann T, Sixt M, Kolanus W. Cytohesin-1 controls the activation of RhoA and modulates integrin-dependent adhesion and migration of dendritic cells. Blood 2009; 113(23): 5801-5810. https://www.ncbi.nlm.nih.gov/pubmed/19346499
- Raffetseder U, Rauen T, Djudjaj S, Kretzler M, En-Nia A, Tacke F, Zimmermann HW, Nelson PJ, Frye BC, Floege J, Stefanidis I, Weber C, Mertens PR. Differential regulation of chemokine CCL5 expression in monocytes/macrophages and renal cells by Y-box protein-1. Kidney Int 2009; 75(2): 185-196. https://www.ncbi.nlm.nih.gov/pubmed/18800033
- Rana OR, Saygili E, Meyer C, Gemein C, Kruttgen A, Andrzejewski MG, Ludwig A, Schotten U, Schwinger RH, Weber C, Weis J, Mischke K, Rassaf T, Kelm M, Schauerte P. Regulation of nerve growth factor in the heart: the role of the calcineurin-NFAT pathway. J Mol Cell Cardiol 2009; 46(4): 568-578. https://www.ncbi.nlm.nih.gov/pubmed/19150448
- Saygili E, Rana OR, Meyer C, Gemein C, Andrzejewski MG, Ludwig A, Weber C, Schotten U, Kruttgen A, Weis J, Schwinger RH, Mischke K, Rassaf T, Kelm M, Schauerte P. The angiotensin-calcineurin-NFAT pathway mediates stretch-induced up-regulation of matrix metalloproteinases-2/-9 in atrial myocytes. Basic Res Cardiol 2009; 104(4): 435-448. https://www.ncbi.nlm.nih.gov/pubmed/19148693
- Schroder K, Kohnen A, Aicher A, Liehn EA, Buchse T, Stein S, Weber C, Dimmeler S, Brandes RP. NADPH oxidase Nox2 is required for hypoxia-induced mobilization of endothelial progenitor cells. Circ Res 2009; 105(6): 537-544. https://www.ncbi.nlm.nih.gov/pubmed/19679834
- Schuh A, Liehn EA, Sasse A, Schneider R, Neuss S, Weber C, Kelm M, Merx MW. Improved left ventricular function after transplantation of microspheres and fibroblasts in a rat model of myocardial infarction. Basic Res Cardiol 2009; 104(4): 403-411. https://www.ncbi.nlm.nih.gov/pubmed/19139948
- Schwartz V, Lue H, Kraemer S, Korbiel J, Krohn R, Ohl K, Bucala R, Weber C, Bernhagen J. A functional heteromeric MIF receptor formed by CD74 and CXCR4. FEBS Lett 2009; 583(17): 2749-2757. https://www.ncbi.nlm.nih.gov/pubmed/19665027
- Segerer S, Johnson Z, Rek A, Baltus T, von Hundelshausen P, Kungl AJ, Proudfoot AE, Weber C, Nelson PJ. The basic residue cluster (55)KKWVR(59) in CCL5 is required for in vivo biologic function. Mol Immunol 2009; 46(13): 2533-2538. https://www.ncbi.nlm.nih.gov/pubmed/19524301
- Shagdarsuren E, Djalali-Talab Y, Aurrand-Lions M, Bidzhekov K, Liehn EA, Imhof BA, Weber C, Zernecke A. Importance of junctional adhesion molecule-C for neointimal hyperplasia and monocyte recruitment in atherosclerosis-prone mice-brief report. Arterioscler Thromb Vasc Biol 2009; 29(8): 1161-1163. https://www.ncbi.nlm.nih.gov/pubmed/19520977
- Soehnlein O. An elegant defense: how neutrophils shape the immune response. Trends Immunol 2009; 30(11): 511-512. https://www.ncbi.nlm.nih.gov/pubmed/19709929
- Soehnlein O. Direct and alternative antimicrobial mechanisms of neutrophil-derived granule proteins. J Mol Med (Berl) 2009; 87(12): 1157-1164. https://www.ncbi.nlm.nih.gov/pubmed/19641860
- Soehnlein O, Drechsler M, Hristov M, Weber C. Functional alterations of myeloid cell subsets in hyperlipidaemia: relevance for atherosclerosis. J Cell Mol Med 2009; 13(11-12): 4293-4303. https://www.ncbi.nlm.nih.gov/pubmed/19900213
- Soehnlein O, Lindbom L. Neutrophil-derived azurocidin alarms the immune system. J Leukoc Biol 2009; 85(3): 344-351. https://www.ncbi.nlm.nih.gov/pubmed/18955543
- Soehnlein O, Lindbom L, Weber C. Mechanisms underlying neutrophil-mediated monocyte recruitment. Blood 2009; 114(21): 4613-4623. https://www.ncbi.nlm.nih.gov/pubmed/19696199
- Soehnlein O, Weber C. Myeloid cells in atherosclerosis: initiators and decision shapers. Semin Immunopathol 2009; 31(1): 35-47. https://www.ncbi.nlm.nih.gov/pubmed/19238385
- Soehnlein O, Weber C, Lindbom L. Neutrophil granule proteins tune monocytic cell function. Trends Immunol 2009; 30(11): 538-546. https://www.ncbi.nlm.nih.gov/pubmed/19699683
- Soehnlein O, Zernecke A, Weber C. Neutrophils launch monocyte extravasation by release of granule proteins. Thromb Haemost 2009; 102(2): 198-205. https://www.ncbi.nlm.nih.gov/pubmed/19652869
- Taylor J, Weber C. European Perspectives - Spotlight: Christian Weber, MD, FESC - FESC Aiming to Selectively Target Platelet Chemokine Heteromers and Macrophage Migration Inhibitory Factor Receptors to Diagnose, Treat, and Prevent Atherosclerosis. Circulation 2009; 119(24): f139-f141. https://www.ahajournals.org/doi/abs/10.1161/CIRCULATIONAHA.109.192208
- Taylor J, Weber C. European Perspectives - Team 2009: Institute for Molecular Cardiovascular Research, Aachen, Germany. Circulation 2009; 119(24): f142-f143. https://www.ahajournals.org/doi/abs/10.1161/CIRCULATIONAHA.109.192208
- Taylor J, Weber C. European Perspectives - Initiatives in cardiovascular Research: the Euregio Cardiovascular Research School. Circulation 2009; 119(24): f144. https://www.ahajournals.org/doi/abs/10.1161/CIRCULATIONAHA.109.192208
- Tjwa M, Moons L, Lutgens E. Pleiotropic role of growth arrest-specific gene 6 in atherosclerosis. Curr Opin Lipidol 2009; 20(5): 386-392. https://www.ncbi.nlm.nih.gov/pubmed/19644365
- von Hundelshausen P, Koenen RR, Weber C. Platelet-mediated enhancement of leukocyte adhesion. Microcirculation 2009; 16(1): 84-96. https://www.ncbi.nlm.nih.gov/pubmed/19115139
- Weber C. Frontiers of vascular biology: mechanisms of inflammation and immunoregulation during arterial remodelling. Thromb Haemost 2009; 102(2): 188-190. https://www.ncbi.nlm.nih.gov/pubmed/19652867
- Weber C. Monozyten und Leukozyten. In: Pötzsch B, Madlener K, eds. Hämostaseologie. Berlin, Heidelberg: Springer Berlin Heidelberg; 2010: 105-111. https://doi.org/10.1007/978-3-642-01544-1_13
- Wojcikiewicz EP, Koenen RR, Fraemohs L, Minkiewicz J, Azad H, Weber C, Moy VT. LFA-1 binding destabilizes the JAM-A homophilic interaction during leukocyte transmigration. Biophys J 2009; 96(1): 285-293. https://www.ncbi.nlm.nih.gov/pubmed/18849408
- Zernecke A, Bidzhekov K, Noels H, Shagdarsuren E, Gan L, Denecke B, Hristov M, Koppel T, Jahantigh MN, Lutgens E, Wang S, Olson EN, Schober A, Weber C. Delivery of microRNA-126 by apoptotic bodies induces CXCL12-dependent vascular protection. Sci Signal 2009; 2(100): ra81. https://www.ncbi.nlm.nih.gov/pubmed/19996457
- Zouggari Y, Ait-Oufella H, Waeckel L, Vilar J, Loinard C, Cochain C, Recalde A, Duriez M, Levy BI, Lutgens E, Mallat Z, Silvestre JS. Regulatory T cells modulate postischemic neovascularization. Circulation 2009; 120(14): 1415-1425. https://www.ncbi.nlm.nih.gov/pubmed/19770391
- Buccione R, Gimona M, Linder S. FEBS workshop: invadopodia podosomes and focal adhesions in tissue invasion. Eur J Cell Biol 2008; 87(8-9): 457-750. https://www.sciencedirect.com/journal/european-journal-of-cell-biology/vol/87/issue/8
- Dragomir E, Manduteanu I, Calin M, Gan AM, Stan D, Koenen RR, Weber C, Simionescu M. High glucose conditions induce upregulation of fractalkine and monocyte chemotactic protein-1 in human smooth muscle cells. Thromb Haemost 2008; 100(6): 1155-1165. https://www.ncbi.nlm.nih.gov/pubmed/19132243
- Gimona M, Buccione R, Courtneidge SA, Linder S. Assembly and biological role of podosomes and invadopodia. Curr Opin Cell Biol 2008; 20(2): 235-41. https://www.ncbi.nlm.nih.gov/pubmed/18337078
- Khandoga AL, Fujiwara Y, Goyal P, Pandey D, Tsukahara R, Bolen A, Guo H, Wilke N, Liu J, Valentine WJ, Durgam GG, Miller DD, Jiang G, Prestwich GD, Tigyi G, Siess W. Lysophosphatidic acid-induced platelet shape change revealed through LPA(1-5) receptor-selective probes and albumin. Platelets 2008; 19(6): 415-27. https://www.ncbi.nlm.nih.gov/pubmed/18925509
- Krump-Konvalinkova V, Chwalla I, Siess W. FTY720 inhibits S1P-mediated endothelial healing: relationship to S1P1-receptor surface expression. Biochem Biophys Res Commun 2008; 370(4): 603-8. https://www.ncbi.nlm.nih.gov/pubmed/18402775
- Reichel CA, Rehberg M, Bihari P, Moser CM, Linder S, Khandoga A, Krombach F. Gelatinases mediate neutrophil recruitment in vivo: evidence for stimulus specificity and a critical role in collagen IV remodeling. J Leukoc Biol 2008; 83(4): 864-74. https://www.ncbi.nlm.nih.gov/pubmed/18174361
- Rode S, Rubic T, Lorenz RL. alpha-Tocopherol disturbs macrophage LXRalpha regulation of ABCA1/G1 and cholesterol handling. Biochem Biophys Res Commun 2008; 369(3): 868-72. https://www.ncbi.nlm.nih.gov/pubmed/18328805
- Schulz C, Konrad I, Sauer S, Orschiedt L, Koellnberger M, Lorenz R, Walter U, Massberg S. Effect of chronic treatment with acetylsalicylic acid and clopidogrel on atheroprogression and atherothrombosis in ApoE-deficient mice in vivo. Thromb Haemost 2008; 99(1): 190-5. https://www.ncbi.nlm.nih.gov/pubmed/18217153
- Schulz C, Penz S, Hoffmann C, Langer H, Gillitzer A, Schneider S, Brandl R, Seidl S, Massberg S, Pichler B, Kremmer E, Stellos K, Schonberger T, Siess W, Gawaz M. Platelet GPVI binds to collagenous structures in the core region of human atheromatous plaque and is critical for atheroprogression in vivo. Basic Res Cardiol 2008; 103(4): 356-67. https://www.ncbi.nlm.nih.gov/pubmed/18431526
- Thal D, Xavier CP, Rosentreter A, Linder S, Friedrichs B, Waha A, Pietsch T, Stumpf M, Noegel A, Clemen C. Expression of coronin-3 (coronin-1C) in diffuse gliomas is related to malignancy. J Pathol 2008; 214(4): 415-24. https://www.ncbi.nlm.nih.gov/pubmed/18189330
- Weinmeister P, Lukowski R, Linder S, Traidl-Hoffmann C, Hengst L, Hofmann F, Feil R. Cyclic guanosine monophosphate-dependent protein kinase I promotes adhesion of primary vascular smooth muscle cells. Mol Biol Cell 2008; 19(10): 4434-41. https://www.ncbi.nlm.nih.gov/pubmed/18685080
- Chellaiah MA, Kuppuswamy D, Lasky L, Linder S. Phosphorylation of a Wiscott-Aldrich syndrome protein-associated signal complex is critical in osteoclast bone resorption. J Biol Chem 2007; 282(13): 10104-16. https://www.ncbi.nlm.nih.gov/pubmed/17283076
- Erl W. Atorvastatin-induced downregulation of survivin and vascular smooth muscle cell apoptosis: a causal relationship in restenosis? Cardiovasc Drugs Ther 2007; 21(3): 141-4. https://www.ncbi.nlm.nih.gov/pubmed/17486302
- Kumar A, Tyagi NK, Goyal P, Pandey D, Siess W, Kinne RK. Sodium-independent low-affinity D-glucose transport by human sodium/D-glucose cotransporter 1: critical role of tryptophan 561. Biochemistry 2007; 46(10): 2758-66. https://www.ncbi.nlm.nih.gov/pubmed/17288452
- Linder S. The matrix corroded: podosomes and invadopodia in extracellular matrix degradation. Trends Cell Biol 2007; 17(3): 107-17. https://www.ncbi.nlm.nih.gov/pubmed/17275303
- Newill H, Loske R, Wagner J, Johannes C, Lorenz RL, Lehmann L. Oxidation products of stigmasterol interfere with the action of the female sex hormone 17beta-estradiol in cultured human breast and endometrium cell lines. Mol Nutr Food Res 2007; 51(7): 888-98. https://www.ncbi.nlm.nih.gov/pubmed/17579897
- Pandey D, Goyal P, Siess W. Lysophosphatidic acid stimulation of platelets rapidly induces Ca2+-dependent dephosphorylation of cofilin that is independent of dense granule secretion and aggregation. Blood Cells Mol Dis 2007; 38(3): 269-79. https://www.ncbi.nlm.nih.gov/pubmed/17321765
- Penz SM, Reininger AJ, Toth O, Deckmyn H, Brandl R, Siess W. Glycoprotein Ibalpha inhibition and ADP receptor antagonists, but not aspirin, reduce platelet thrombus formation in flowing blood exposed to atherosclerotic plaques. Thromb Haemost 2007; 97(3): 435-43. https://www.ncbi.nlm.nih.gov/pubmed/17334511
- Trasak C, Zenner G, Vogel A, Yuksekdag G, Rost R, Haase I, Fischer M, Israel L, Imhof A, Linder S, Schleicher M, Aepfelbacher M. Yersinia protein kinase YopO is activated by a novel G-actin binding process. J Biol Chem 2007; 282(4): 2268-77. https://www.ncbi.nlm.nih.gov/pubmed/17121817
- Tyagi NK, Kumar A, Goyal P, Pandey D, Siess W, Kinne RK. D-Glucose-recognition and phlorizin-binding sites in human sodium/D-glucose cotransporter 1 (hSGLT1): a tryptophan scanning study. Biochemistry 2007; 46(47): 13616-28. https://www.ncbi.nlm.nih.gov/pubmed/17983207
- Daub K, Langer H, Seizer P, Stellos K, May AE, Goyal P, Bigalke B, Schonberger T, Geisler T, Siegel-Axel D, Oostendorp RA, Lindemann S, Gawaz M. Platelets induce differentiation of human CD34+ progenitor cells into foam cells and endothelial cells. FASEB J 2006; 20(14): 2559-2561. https://www.ncbi.nlm.nih.gov/pubmed/17077283
- Goyal P, Pandey D, Siess W. Phosphorylation-dependent regulation of unique nuclear and nucleolar localization signals of LIM kinase 2 in endothelial cells. J Biol Chem 2006; 281(35): 25223-25230. https://www.ncbi.nlm.nih.gov/pubmed/16820362
- Gringel A, Walz D, Rosenberger G, Minden A, Kutsche K, Kopp P, Linder S. PAK4 and alphaPIX determine podosome size and number in macrophages through localized actin regulation. J Cell Physiol 2006; 209(2): 568-579. https://www.ncbi.nlm.nih.gov/pubmed/16897755
- Kopp P, Lammers R, Aepfelbacher M, Woehlke G, Rudel T, Machuy N, Steffen W, Linder S. The kinesin KIF1C and microtubule plus ends regulate podosome dynamics in macrophages. Mol Biol Cell 2006; 17(6): 2811-2823. https://www.ncbi.nlm.nih.gov/pubmed/16554367
- Linder S. Proceedings of the Adhesion Meeting, Munich, Germany, April 28-30, 2005. Eur J Cell Biol 2006; 85(3-4): 143-332. https://www.ncbi.nlm.nih.gov/pubmed/16546555
- Massberg S, Konrad I, Schurzinger K, Lorenz M, Schneider S, Zohlnhoefer D, Hoppe K, Schiemann M, Kennerknecht E, Sauer S, Schulz C, Kerstan S, Rudelius M, Seidl S, Sorge F, Langer H, Peluso M, Goyal P, Vestweber D, Emambokus NR, Busch DH, Frampton J, Gawaz M. Platelets secrete stromal cell-derived factor 1alpha and recruit bone marrow-derived progenitor cells to arterial thrombi in vivo. J Exp Med 2006; 203(5): 1221-1233. https://www.ncbi.nlm.nih.gov/pubmed/16618794
- Pandey D, Goyal P, Bamburg JR, Siess W. Regulation of LIM-kinase 1 and cofilin in thrombin-stimulated platelets. Blood 2006; 107(2): 575-583. https://www.ncbi.nlm.nih.gov/pubmed/16219803
- Pfrommer CA, Erl W, Weber PC. Docosahexaenoic acid induces ciap1 mRNA and protects human endothelial cells from stress-induced apoptosis. Am J Physiol Heart Circ Physiol 2006; 290(6): H2178-2186. https://www.ncbi.nlm.nih.gov/pubmed/16473961
- Rubic T, Lorenz RL. Downregulated CD36 and oxLDL uptake and stimulated ABCA1/G1 and cholesterol efflux as anti-atherosclerotic mechanisms of interleukin-10. Cardiovasc Res 2006; 69(2): 527-535. https://www.ncbi.nlm.nih.gov/pubmed/16336952
- Schroder A, Schroder B, Roppenser B, Linder S, Sinha B, Fassler R, Aepfelbacher M. Staphylococcus aureus fibronectin binding protein-A induces motile attachment sites and complex actin remodeling in living endothelial cells. Mol Biol Cell 2006; 17(12): 5198-5210. https://www.ncbi.nlm.nih.gov/pubmed/17021255
- Siess W. Platelet interaction with bioactive lipids formed by mild oxidation of low-density lipoprotein. Pathophysiol Haemost Thromb 2006; 35(3-4): 292-304. https://www.ncbi.nlm.nih.gov/pubmed/16877878
- Toth O, Calatzis A, Penz S, Losonczy H, Siess W. Multiple electrode aggregometry: a new device to measure platelet aggregation in whole blood. Thromb Haemost 2006; 96(6): 781-788. https://www.ncbi.nlm.nih.gov/pubmed/17139373
- Ussar S, Wang HV, Linder S, Fassler R, Moser M. The Kindlins: subcellular localization and expression during murine development. Exp Cell Res 2006; 312(16): 3142-3151. https://www.ncbi.nlm.nih.gov/pubmed/16876785
- Weber GF, Gaertner FC, Erl W, Janssen KP, Blechert B, Holzmann B, Weighardt H, Essler M. IL-22-mediated tumor growth reduction correlates with inhibition of ERK1/2 and AKT phosphorylation and induction of cell cycle arrest in the G2-M phase. J Immunol 2006; 177(11): 8266-8272. https://www.ncbi.nlm.nih.gov/pubmed/17114505
- Bu DX, Erl W, de Martin R, Hansson GK, Yan ZQ. IKKbeta-dependent NF-kappaB pathway controls vascular inflammation and intimal hyperplasia. FASEB J 2005; 19(10): 1293-5. https://www.ncbi.nlm.nih.gov/pubmed/15939736
- Durgam GG, Virag T, Walker MD, Tsukahara R, Yasuda S, Liliom K, van Meeteren LA, Moolenaar WH, Wilke N, Siess W, Tigyi G, Miller DD. Synthesis, structure-activity relationships, and biological evaluation of fatty alcohol phosphates as lysophosphatidic acid receptor ligands, activators of PPARgamma, and inhibitors of autotaxin. J Med Chem 2005; 48(15): 4919-30. https://www.ncbi.nlm.nih.gov/pubmed/16033271
- Erl W. Statin-induced vascular smooth muscle cell apoptosis: a possible role in the prevention of restenosis? Curr Drug Targets Cardiovasc Haematol Disord 2005; 5(2): 135-44. https://www.ncbi.nlm.nih.gov/pubmed/15853755
- Gimona M, Grashoff C, Kopp P. Oktoberfest for adhesion structures. EMBO Rep 2005; 6(10): 922-6. https://www.ncbi.nlm.nih.gov/pubmed/16170307
- Gopfert MS, Siedler F, Siess W, Sellmayer A. Structural identification of oxidized acyl-phosphatidylcholines that induce platelet activation. J Vasc Res 2005; 42(2): 120-32. https://www.ncbi.nlm.nih.gov/pubmed/15665547
- Goyal P, Pandey D, Behring A, Siess W. Inhibition of nuclear import of LIMK2 in endothelial cells by protein kinase C-dependent phosphorylation at Ser-283. J Biol Chem 2005; 280(30): 27569-77. https://www.ncbi.nlm.nih.gov/pubmed/15923181
- Kim HJ, Vosseler CA, Weber PC, Erl W. Docosahexaenoic acid induces apoptosis in proliferating human endothelial cells. J Cell Physiol 2005; 204(3): 881-8. https://www.ncbi.nlm.nih.gov/pubmed/15795939
- Krump-Konvalinkova V, Yasuda S, Rubic T, Makarova N, Mages J, Erl W, Vosseler C, Kirkpatrick CJ, Tigyi G, Siess W. Stable knock-down of the sphingosine 1-phosphate receptor S1P1 influences multiple functions of human endothelial cells. Arterioscler Thromb Vasc Biol 2005; 25(3): 546-52. https://www.ncbi.nlm.nih.gov/pubmed/15618544
- Linder S. Understanding cell-matrix contacts with the help of nucleofection. Amexa Newsletter 2005; 6(11).
- Linder S, Kopp P. Podosomes at a glance. J Cell Sci 2005; 118(Pt 10): 2079-82. https://www.ncbi.nlm.nih.gov/pubmed/15890982
- Osiak AE, Zenner G, Linder S. Subconfluent endothelial cells form podosomes downstream of cytokine and RhoGTPase signaling. Exp Cell Res 2005; 307(2): 342-53. https://www.ncbi.nlm.nih.gov/pubmed/15894313
- Penz S, Reininger AJ, Brandl R, Goyal P, Rabie T, Bernlochner I, Rother E, Goetz C, Engelmann B, Smethurst PA, Ouwehand WH, Farndale R, Nieswandt B, Siess W. Human atheromatous plaques stimulate thrombus formation by activating platelet glycoprotein VI. FASEB J 2005; 19(8): 898-909. https://www.ncbi.nlm.nih.gov/pubmed/15923400
- Tyagi NK, Goyal P, Kumar A, Pandey D, Siess W, Kinne RK. High-yield functional expression of human sodium/d-glucose cotransporter1 in Pichia pastoris and characterization of ligand-induced conformational changes as studied by tryptophan fluorescence. Biochemistry 2005; 44(47): 15514-24. https://www.ncbi.nlm.nih.gov/pubmed/16300400